Journal of Tissue Engineering and Regenerative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Biomimetic fetal rotation bioreactor for engineering bone tissues —Effect of cyclic strains on upregulation of osteogenic gene expression
This study introduces a multimodal bioreactor system that allows application of cyclic compressive strains on premature bone grafts that are cultured under biaxial rotation (chamber rotation about 2 axes) conditions for bone tissue engineering. The bioreactor is integrated with sensors for dissolved oxygen levels and pH that allow real‐time, non‐invasive monitoring of the culture parameters. Mesenchymal stem cells‐seeded polycaprolactone–β‐tricalcium phosphate scaffolds were cultured in this bioreactor over 2 weeks in 4 different modes—static, cyclic compression, biaxial rotation, and multimodal (combination ...
Source: Journal of Tissue Engineering and Regenerative Medicine - January 25, 2018 Category: Biotechnology Authors: Akhilandeshwari Ravichandran, Feng Wen, Jing Lim, Mark Seow Khoon Chong, Jerry K.Y. Chan, Swee ‐Hin Teoh Tags: RESEARCH ARTICLE Source Type: research

Decellularized human liver extracellular matrix (hDLM) ‐mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs)
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 21, 2018 Category: Biotechnology Source Type: research

Characterization of costal cartilage and its suitability as a cell source for articular cartilage tissue engineering
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 21, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 21, 2018 Category: Biotechnology Source Type: research

Decellularized human liver extracellular matrix (hDLM) ‐mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs)
Abstract Liver tissue engineering has emerged as a promising approach in organ transplantation but has been hampered by the lack of a reliable and readily available cell source. Human induced pluripotent stem cells hiPSCs have been highlighted as a desirable source, due to their differentiation potential, ability to self‐renew, and the possibility of making patient‐specific cells. We developed a decellularization protocol that efficiently removes cellular material while retaining extracellular matrix components. Subsequently, hiPSCs were differentiated on decellularized human liver extracellular matrix (hDLM) scaffolds...
Source: Journal of Tissue Engineering and Regenerative Medicine - January 21, 2018 Category: Biotechnology Authors: Maria Jaramillo, Heidi Yeh, Martin L. Yarmush, Basak E. Uygun Tags: RESEARCH ARTICLE Source Type: research

Human dental stem cell derived transgene ‐free iPSCs generate functional neurons via embryoid body‐mediated and direct induction methods
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 17, 2018 Category: Biotechnology Source Type: research

Bone marrow transplantation improves motor activity in a mouse model of ataxia
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 17, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 17, 2018 Category: Biotechnology Source Type: research

Improvement of islet function and survival by integration of perfluorodecalin into microcapsules in vivo and in vitro
In conclusion, integration of PFD in alginate microcapsules improved islet function and survival by minimizing the hypoxic damage of islets after intraperitoneal transplantation. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 12, 2018 Category: Biotechnology Authors: Sang ‐Ho Lee, Heon‐Seok Park, Yeoree Yang, Eun‐Young Lee, Ji‐Won Kim, Gilson Khang, Kun‐Ho Yoon Tags: RESEARCH ARTICLE Source Type: research

Enhanced bone regeneration and visual monitoring via super ‐paramagnetic iron oxide nanoparticle‐scaffold in rats
In conclusion, good visibility on MRI and enhanced regeneration of bone can be obtained by implanting SPIONs‐GS in vivo without using an external magnetic field. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 12, 2018 Category: Biotechnology Authors: Shuying Hu, Yi Zhou, Yantao Zhao, Yang Xu, Feimin Zhang, Ning Gu, Junqing Ma, Mark A. Reynolds, Yang Xia, Hockin H.K. Xu Tags: RESEARCH ARTICLE Source Type: research

Regenerative effects of human embryonic stem cell ‐derived neural crest cells for treatment of peripheral nerve injury.
In this study, neural crest cells were differentiated from human embryonic stem cells. The differentiated cells exhibited typical stellate morphology and protein expression signatures that were comparable to native neural crest. Conditioned media harvested from the differentiated cells contained a range of biologically active trophic factors and was able to stimulate in vitro neurite outgrowth. Differentiated neural crest cells were seeded into a biodegradable nerve conduit and their regeneration potential was assessed in a rat sciatic nerve injury model. A robust regeneration front was observed across the entire width of ...
Source: Journal of Tissue Engineering and Regenerative Medicine - January 12, 2018 Category: Biotechnology Authors: Iwan Jones, Liudmila N. Novikova, Lev N. Novikov, Monika Renardy, Andreas Ullrich, Mikael Wiberg, Leif Carlsson, Paul J. Kingham Tags: RESEARCH ARTICLE Source Type: research

Dendrimers: Breaking the paradigm of current musculoskeletal autoimmune therapies
Journal of Tissue Engineering and Regenerative Medicine, Page e1796-e1812, August 2018. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 11, 2018 Category: Biotechnology Authors: Daniel B.Rodrigues , Joaquim M.Oliveira , T írcia C.Santos , Rui L.Reis Source Type: research

An endochondral ossification approach to early ‐stage bone repair: Use of tissue‐engineered hypertrophic cartilage constructs as primordial templates for weight‐bearing bone repair
In this study, we demonstrate that tissue‐engineered hypertrophically‐primed cartilage constructs can be developed from collagen‐based scaffolds cultured with mesenchymal stem cells. These constructs were subsequently implanted into femoral defects in rats. It was evident that the constructs could support enhanced early‐stage healing at 4 weeks of these weight‐bearing femoral bone defects compared to untreated defects. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 11, 2018 Category: Biotechnology Authors: Amos Matsiko, Emmet M. Thompson, Cai Lloyd ‐Griffith, Gráinne M. Cunniffe, Tatiana Vinardell, John P. Gleeson, Daniel J. Kelly, Fergal J. O'Brien Tags: SHORT COMMUNICATION Source Type: research