Journal of Tissue Engineering and Regenerative Medicine 
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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 11, 2018 Category: Biotechnology Source Type: research
Four and a half domain 2 (FHL2) scaffolding protein is a marker of connective tissues of developing digits and regulates fibrogenic differentiation of limb mesodermal progenitors
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 7, 2018 Category: Biotechnology Source Type: research
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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 7, 2018 Category: Biotechnology Source Type: research
Enhanced bone regeneration and visual monitoring via superparamagnetic iron oxide nanoparticle scaffold in rats
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 6, 2018 Category: Biotechnology Source Type: research
Evaluation of an ovary ‐on‐a‐chip in large mammalian models: Species specificity and influence of follicle isolation status
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 6, 2018 Category: Biotechnology Source Type: research
An intervertebral disc whole organ culture system to investigate proinflammatory and degenerative disc disease condition
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 6, 2018 Category: Biotechnology Source Type: research
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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 6, 2018 Category: Biotechnology Source Type: research
Enhanced bone regeneration and visual monitoring via superparamagnetic iron oxide nanoparticle scaffold in rats
In conclusion, good visibility on MRI and enhanced regeneration of bone can be obtained by implanting SPIONs‐GS in vivo without using an external magnetic field. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - February 6, 2018 Category: Biotechnology Authors: Shuying Hu, Yi Zhou, Yantao Zhao, Yang Xu, Feimin Zhang, Ning Gu, Junqing Ma, Mark A. Reynolds, Yang Xia, Hockin H.K. Xu Tags: RESEARCH ARTICLE Source Type: research
Activated platelet ‐rich plasma (PRP) improves cartilage regeneration using adipose stem cells encapsulated in a 3D alginate scaffold
Abstract
In the current study the effect of superimposing platelet‐rich plasma (PRP) on different culture mediums in a three‐dimensional (3D) alginate scaffold encapsulated with adipose mesenchymal stem cells (ADSCs) for cartilage tissue repair is reported. The 3D alginate scaffolds with co‐administration of PRP and/or chondrogenic supplements had a significant effect on the differentiation of ADSCs into mature cartilage, as assessed by evaluation of the expression of cartilage related markers of Sox9, Collagen II, Aggrecan and collagen and glycosaminoglycan assays. For in vivo studies, following induction of osteoch...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 1, 2018 Category: Biotechnology Authors: Mohammad ‐Hossein Beigi, Atefeh Atefi, Hamid‐Reza Ghanaei, Sheyda Labbaf, Fatemeh Ejeian, Mohammad‐Hossein Nasr‐Esfahani Tags: RESEARCH ARTICLE Source Type: research
A bilayer photoreceptor ‐retinal tissue model with gradient cell density design: a study of microvalve‐based bioprinting
Abstract
ARPE‐19 and Y79 cells were precisely and effectively delivered to form an in vitro retinal tissue model via 3D cell bioprinting technology. The samples were characterized by cell viability assay, hematoxylin and eosin (HE) and immunofluorescent staining, scanning electrical microscopy (SEM) and confocal microscopy etc. The bioprinted ARPE‐19 cells formed a high‐quality cell monolayer in 14 days. Manually seeded ARPE‐19 cells were poorly controlled during and after cell seeding, and they aggregated to form uneven cell layer. The Y79 cells were subsequently bioprinted on the ARPE‐19 cell monolayer to form ...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 1, 2018 Category: Biotechnology Authors: Pujiang Shi, Tan Yong Sheng Edgar, Wai Yee Yeong, Li Hoi Yeung, Augustinus Laude Tags: RESEARCH ARTICLE Source Type: research
Functional collagen conduits combined with human mesenchymal stem cells promote regeneration after sciatic nerve transection in dogs
In this study, we attempted to bridge 3.5‐cm defects of the sciatic nerve with a longitudinally‐oriented collagen conduit (LOCC) loaded with human umbilical cord mesenchymal stem cells (hUC‐MSCs). The LOCC contains a bundle of longitudinally‐aligned collagenous fibers enclosed in a hollow collagen tube. Our previous studies showed that an LOCC combined with neurotrophic factors enhances peripheral nerve regeneration. However, it remained unknown whether an LOCC seeded with hUC‐MSCs could also promote regeneration. In the present study, using various histological and electrophysiological analyses, we found that an...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 1, 2018 Category: Biotechnology Authors: Yi Cui, Yao Yao, Yannan Zhao, Zhifeng Xiao, Zongfu Cao, Sufang Han, Xing Li, Yong Huan, Juli Pan, Jianwu Dai Tags: RESEARCH ARTICLE Source Type: research
Simvastatin improves oral implant osseointegration via enhanced autophagy and osteogenesis of BMSCs and inhibited osteoclast activity
Abstract
Dental implants have become a widely accepted and successful treatment for fully and partially edentulous patients. Simvastatin has been applied to improve and accelerate the osseointegration of implants by increasing the quantity and quality of bone tissue. However, its potential mechanism has not been elucidated completely. Here, we found that simvastatin significantly enhanced the autophagy level of jaw‐derived bone marrow stromal cells (BMSCs) and alleviated production of reactive oxygen species under unfavourable conditions. Simvastatin promoted osteogenic differentiation of BMSCs via enhanced autophagy. Fu...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 1, 2018 Category: Biotechnology Authors: Rongyao Xu, Guanghui Shi, Ling Xu, Qinyi Gu, Yu Fu, Ping Zhang, Jie Cheng, Hongbing Jiang Tags: RESEARCH ARTICLE Source Type: research
