Anti-fibrotic Therapies for Prevention of Abdominal Adhesion
We present a novel pre-clinical rodent model of AA treated with human placental stem cells (hPSC), their anti-inflammatory products (conditioned media, CM) and barrier hydrogel therapies for adhesion prevention. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Samuel P. Carmichael, Prafulla K. Chandra, John W. Vaughan, John B. Holcomb, Anthony J. Atala Tags: General Surgery Source Type: research

Application of the Predictive Optimal Trees in Emergency Surgery Risk Calculator (POTTER) to Emergency Surgical Debridement for Necrotizing Skin and Soft Tissue Infection
The Predictive OpTimal Trees in Emergency Surgery Risk calculator (POTTER) has been effective in addressing the need for a dynamic, non-linear risk assessment tool for emergency surgical procedures at large, though there is no data to suggest that it is equally effective for all types of emergency operations. The present study examines the accuracy of POTTER when used to assess likelihood of morbidity from any cause following surgical debridement for necrotizing skin and soft tissue infections (NSSTI). (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Zachary Lawrence, Seungjun Kim, Edie Y. Chan Tags: General Surgery Source Type: research

Association Between Preoperative Blood Transfusion and Postoperative Pulmonary Embolism
Approximately 0.85% of patients requiring non-elective surgery in the U.S. receive preoperative transfusion of packed red blood cells (PRBCs). In addition, approximately 0.32% of patients requiring non-elective surgery are subsequently found to have a Pulmonary Embolism (PE), an outcome with an untreated mortality greater than 30%. We investigated the association between preoperative PRBC transfusion and postoperative PE. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Warren C. Rehrer, Joseph R. Rinaldi, Brandon O. Boyd, Rebecca L. Toonkel, No ël C. Barengo Tags: General Surgery Source Type: research

Associations Between Preoperatively Predicted Postoperative Complications in American College of Surgeons NSQIP Patients
The Surgical Risk Preoperative Assessment System (SURPAS) produces preoperative risk profiles of patients ’ probabilities of 12 adverse postoperative outcomes. Little is known about the associations between these probabilities. We aimed to describe relationships between preoperatively predicted risks in a diverse, multicenter database to help guide risk-mitigation interventions. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Helen J. Madsen, Robert A. Meguid, Michael R. Bronsert, Adam R. Dyas, Kathryn Colborn L, Anne Lambert-Kerzner, William G. Henderson Tags: General Surgery Source Type: research

Comparing Functional Outcomes in Minimally Invasive vs Open Inguinal Herniorrhaphy Using the Army Physical Fitness Test
The advantages of minimally invasive (MIS) inguinal herniorrhaphy over open repair continue to be debated. We compared MIS to open herniorrhaphy utilizing the Army Physical Fitness Test (APFT) as an outcome measure. The three-component APFT (comprising push-ups, sit-ups and a two-mile run) is scored on a normalized scale from 0 to 300 and taken semiannually by an active-duty military population available for study. Herein, the APFT has been used as a unique measure of functional outcomes and an objective, valid and reliable measure of maximal physical effort. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Adam J. Kaplan, Dwayne A. Nelson, Joseph D. Bozzay, John D. Ritchie, Daniel R. Clifton, Daniel B. Edgeworth, Patricia A. Deuster, Shaun R. Brown Tags: General Surgery Source Type: research

Compliance with Guideline-indicated Venous Thromboembolism Prophylaxis in Elective Surgical Procedures: A Single Health System Evaluation
Venous thromboembolism (VTE) remains a major modifiable source of postoperative morbidity and mortality across surgical specialties. As a patient safety indicator (AHRQ PSI-12), healthcare systems are incentivized to reduce VTE complications. However, compliance to VTE practice guidelines remains uncertain. We therefore aimed to determine the utilization and impact of Caprini guideline-indicated VTE prophylaxis in surgical patients across our multistate health system. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Michael A. Edwards, Aaron Spaulding, Shalmali R. Borkar, Pablo Moreno Franco, Mark D. Tyson, Elizabeth B. Habermann, Basel A. Sharaf, Dorin T. Colibaseanu Tags: General Surgery Source Type: research

COVID-19 Impact on Elective Surgery and Hospital Finances
The COVID-19 pandemic prompted to temporarily cease all elective surgery. Elective surgery represents a disproportionate share of the revenue for hospitals, placing them under potential financial stress. The study sought to determine the reduction in surgical volume and the economic impact across service lines and geographical region. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Elizabeth M. Spitz, Young K. Hong, RIchard Sensenig, Syed A. Daniyal, Sushni Mukkamalla, Ashley Amundson, Michael A. Curry, Shivani Rao Tags: General Surgery Source Type: research

Development and Implementation of a Surgical Equity Center for Vulnerable Patients with Surgical Diseases
Patients marginalized on the basis of sociodemographic hierarchies bear a disproportionate burden of surgical disease. These vulnerable patients face a large burden of emergency surgery with higher associated complexity, morbidity, and mortality. Our center aims to provide gold-standard surgical care for vulnerable patients in our city. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Carrie Zimmerman, W.h.i.t.n.e.y. Orji, Alyssa Civantos, Kevin Zhang, Cindy Zhao, Erin L. Fischer, Alan Herbst, Matthew Goldshore, Jon B. Morris, of the Center for Surgical Health Tags: General Surgery Source Type: research

Diagnosis of Recurrent Inguinal Hernia on CT Is Often Pseudo-recurrence at a Single Institution
Inguinal hernias are one of the most commonly repaired hernias. Minimally invasive (laparoscopic and robotic) repairs have become an increasing option for patients. Computed Tomography (CT) of the Abdomen and Pelvis in addition to clinical exam are used to diagnose recurrent inguinal hernias. Often, CT scans are limited in differentiating cord lipomas, commonly identified as pseudo-recurrence, from actual recurrence. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Martha Menchaca, Mokunfayo Fajemisin, Heng Wang, Patrice Frederick Tags: General Surgery Source Type: research

Did We STOP-IT? a Population-Based Interrupted Time Series Analysis of Antimicrobial Duration for Intra-abdominal Infections Before and after the Publication of a Landmark Randomized Controlled Trial
In May 2015, the STOP-IT randomized controlled trial showed equivalent outcomes between short-course (four days following source control) and clinically-determined antimicrobial duration for complicated intra-abdominal infection (CIAI). We aimed to quantify the effect of this trial on antimicrobial prescribing for CIAI in Calgary, Alberta. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Joshua S. Ng, Andrea Soo, Paul B. McBeth, Ori D. Rotstein, Danny J. Zuege, Daniel Gregson, Christopher Doig, Henry T. Stelfox, Daniel Niven Tags: General Surgery Source Type: research

Epidemiology of Parastomal Hernia Repair in the US: A NSQIP Analysis
Parastomal hernia (PSH) is a common complication following stoma creation. While both open and laparoscopic repair options exist, the utilization of either repair type is not well characterized, particularly in recent cohorts. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Mark Eid, Robert Shaw, Brent White Tags: General Surgery Source Type: research

Evaluation of Extended View Totally Extra-peritoneal Approach for Repair of Ventral Hernia
Ventral Hernia (VH) repair is undergoing a paradigm shift with introduction of numerous techniques. Extended-view Totally Extraperitoneal (eTEP) is a minimally invasive approach introduced in 2016. It follows the principles of retro-muscular, pre-peritoneal mesh placement over a giant visceral peritoneal sac. This avoids complications of intra-peritoneal mesh with better outcomes. This approach can be combined with TAR for large hernias. As there is limited literature on a larger population, we conducted a Midterm analysis of this approach. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Atul Mishra, Harmandeep S. Jabbal, Amandeep S. Nar, Rochan Mangla, Ravinder Pal S. Babra, Akashi Mishra, Priyanka Sharma Tags: General Surgery Source Type: research

Is Surgery with General Anesthesia a Safe Option in Asymptomatic COVID-19 Positive Patients?
This study evaluates outcomes in patients undergoing urgent surgery with GET unrelated to their asymptomatic COVID-19 infection. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Noor Habboosh, Benjamin J. Pomy, Joseph Devlin, Robyn A. Macsata, Anton N. Sidawy, Salim Lala Tags: General Surgery Source Type: research

Locoregional Anesthesia for Major Surgery in Frail Adults May Reduce Postoperative Morbidity and Mortality
Frail patients have an increased risk of postoperative morbidity and mortality, and there is an urgent need for interventions to improve outcomes in this vulnerable group. We hypothesized that using locoregional rather than general anesthesia would significantly reduce morbidity and mortality for frail patients having complex surgery. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Jennie Meier, Audrey R. Stevens, Miles Berger, Munro Cullum, Cynthia J. Brown, Courtney Balentine Tags: General Surgery Source Type: research

Management of Upper Gastrointestinal Tract Leaks Using Endoluminal Vacuum Therapy: 10-years ’ Experience of a Specialist Esophago-gastric Center
We report the outcomes for patients with UGI leaks treated with EVT in a tertiary UK hospital over a 10-year period. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - October 22, 2021 Category: Surgery Authors: Zeeshan Afzal, Stavros Gourgiotis, Richard H. Hardwick, Peter M. Safranek, Vijay Sujendran, John Bennett, J. Robert O'Neill, Ayesha Noorani, Andrew Hindmarsh Tags: General Surgery Source Type: research