Three-Dimensional Cultured Human Rotator Cuff Spheroids: tendon-related Marker Expression and Efficacy in Rat Rotator Cuff Repair Model
In this study, we hypothesized that spheroids of human rotator cuff-derived cells obtained from three-dimensional culture would have higher levels of gene expression and protein concentrations involved in rotator cuff regeneration and healing than cells obtained from two-dimensional culture. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Takahio Furukawa, Yutaka Mifune, Atsuyuki Inui, Tatsuo Kato, Masaya Kusunose, Shunsaku Takigami, Takeshi Kokubu Source Type: research

Correlation analysis of the histological degeneration in a torn supraspinatus tendon with the clinical findings in arthroscopic rotator cuff repair
Retear after arthroscopic rotator cuff repair (ARCR) is not rare, and prognostic factors include tear size and fatty infiltration of the rotator cuff (RC) muscle. We have previously demonstrated that severe histological degeneration of the torn supraspinatus tendon on Bonar scoring is a predictor of post-ARCR retear. However, the factors associated with the histological findings of torn supraspinatus tendons remain unclear. Herein, we aimed to identify the clinical factors that correlate with the degree of histological degeneration in the tendon stump of patients undergoing ARCR for full-thickness tears. (Source: Journal o...
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Takuya Tokunaga, Tatsuki Karasugi, Shuntaro Tanimura, Yuko Fukuma, Katsumasa Ideo, Ryuji Yonemitsu, Takeshi Miyamoto Source Type: research

Effect over the stability of acromioclavicular and coracoclavicular ligament on acromioclavicular joint dislocation using a cadaver model
Dislocation of the acromioclavicular joint (ACJ) leads to upper clavicular instability when the acromioclavicular ligament (AC) and coracoclavicular ligaments (CC) are torn. Surgery is indicated for Rockwood classification of dislocations type 3 or higher. Although CC reconstruction alone has been used previously, posterior instability is possible. AC reconstruction is essential for overall stability and has been shown to increase posterior stability. Previous biomechanical studies on ACJ stability were conducted on dissected bones, muscles, and ligaments using AC or CC resection. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Fumiya Hattori, Eiko Hashimoto, Shohei Ise, Kenta Inagaki, Yu Hiraoka, Taro Akiyama, Fumihide Terakawa, Nobuyasu Ochiai Source Type: research

Glenoid defect size increases with infrequent resorption of the bone fragment in shoulders with recurrent anterior instability
In recurrent anterior instability, the bone fragment of a bony Bankart lesion is often smaller than that of a glenoid defect. The purpose of the present study was to clarify the changes to both the bone fragment and glenoid defect over time in a single patient. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Shigeto Nakagawa, Tatsuo Mae, Rhohei Uchida Source Type: research

Does the improvement of supraspinatus atrophy affect long-term postoperative outcomes?
This study aimed to determine whether improvement in supraspinatus atrophy affects long-term postoperative outcomes. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Yuya Kotagiri, Yukihiko Hata, Norio Ishigaki Source Type: research

Inferior subscapularis and hypertrophic teres minor contribute to preventing superior migration of humeral head
This study evaluated the correlation between the atrophy of superior and inferior SSc muscle and the degree of superior migration of the humeral head in patients with RCTs involving atrophic supraspinatus (SSP), ISP, and hypertrophic TM. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Toshifumi Tamura, Kenshi Kikukawa, Takashi Araki Source Type: research

Morphological evaluation of the scapula related to the development of rotator cuff tears using a homologous model
The overall shape of the scapula was clarified by extracting variables representing morphological variations using a 3D homologous model. Based on this, morphological characteristics of the scapula in rotator cuff tears are clarified. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Ryo Tokita, Hajime Toda, Rui Imamura, Akira Sugi, Yuji Shibayama Source Type: research

Long-term outcomes of hemiarthroplasty and rotator cuff reconstruction in patients with cuff tear arthropathy
This study aimed to evaluate the outcomes of small-head hemiarthroplasty and rotator cuff reconstruction in patients with cuff tear arthropathy (CTA) over 10 years. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Chika Yoshioka, Naoki Suenaga, Naomi Oizumi, Shintaro Yamane, Yukiyoshi Hisada, Tomoya Matsuhashi, Naoki Miyoshi Source Type: research

Lifestyle and physical activity of elderly patients with asymptomatic rotator cuff tears
This study aimed to evaluate the course of asymptomatic rotator cuff tears in elderly individuals and analyze the lifestyle and physical activity of those who remained asymptomatic. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Hitoshi Koda, Yoshihiro Kai, Noriyuki Kida, Yuichiro Miura, Hideaki Fukushima, Hiromi Kondo, Minoru Takeshima, Toru Morihara Source Type: research

Prospective randomized study on the effect of disinfectants on suture contamination in arthroscopic rotator cuff repair
Cutibacterium acnes is a common cause of postoperative infections following shoulder surgery, with a higher incidence in males. In arthroscopic surgery, sutures are considered a source of infection. Several studies have been conducted on the effectiveness of disinfectants in preventing suture contamination; however, there is no consensus on disinfectant selection for the prevention of Cutibacterium acnes infection. This prospective, randomized, comparative study aimed to evaluate the effectiveness of disinfectants in preventing suture contamination during arthroscopic rotator cuff repair. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Hideki Kamijo, Norimasa Takahashi, Keisuke Matsuki, Yuu Sasaki, Yusuke Ueda, Shota Hoshika, Tomoyuki Matsuba, Tasuku Kiyuna, Tomoshige Tamaki, Ryo Haraguchi Source Type: research

Antioxidants accelerate tendon-to-bone healing after rotator cuff repair surgery
This study aimed to investigate the effects of reduction of oxidative stress induced by antioxidants such as N-acetylcysteine (NAC) and vitamin C (VC) on rotator cuff repair in a rotator cuff repair model in rats. Infraspinatus tendon was ruptured in 48 rats and repaired 1 week later. Rats were divided into 3 groups: NAC group, VC group, or control group, and were administered NAC, VC, or distilled water respectively. The specimens were collected at 3, 6, and 12 weeks after repair. Histological evaluation was performed using hematoxylin/eosin and toluidine blue staining, and oxidative stress was evaluated using dihydroethi...
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Hirohisa Uehara, Yoshiaki Itoigawa, Daichi Morikawa, Akihisa Koga, Hironori Tsurukami, Muneaki Ishijima Source Type: research

Infraspinatus shows earlier and stronger degeneration than supraspinatus and subscapularis after massive rotator cuff tear
Muscle atrophy and fatty infiltration (FI) result from rotator cuff tear, which makes operative repair difficult. Irreversible degeneration after multiple tendon ruptures is common among elderly patients, and the underlying mechanisms remain elusive. In addition, while all muscles constituting the rotator cuff should be investigated, only the supraspinatus has been targeted in previous studies. We evaluated the degeneration of each muscle in the mice to reveal the mechanisms of degeneration. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Takayuki Seto, Takumi Nakamura, Ryosuke Tsujisaka, Yuki Yoshida, Yuhei Takada, Hideyuki Shirasawa, Noboru Matsumura Source Type: research

Is the subscapularis function preserved after the Latarjet procedure?
After the Latarjet procedure, the range of internal rotation is reported to be limited compared to iliac crest bone graft procedure. We hypothesized that the conjoint tendon which crosses over the subscapularis muscle might suppress the normal movement of the muscle. The purpose of this study was to evaluate the subscapularis activity using positron emission tomography (PET) in patients after the Latarjet procedure. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Kazuho Aizawa, Nobuyuki Yamamoto, Jun Kawami, Kiyotsugu Shinagawa, Hideaki Nagamoto, Toshimi Aizawa, Eiji Itoi Source Type: research

Effects of glutaminase 1 inhibitor on rotator cuff derived cells
In this study, we evaluated the effects of GLS1 inhibitors on human degenerated rotator cuff-derived cells. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Tatsuo Kato, Yutaka Mifune, Atsuyuki Inui, Tomoya Yoshikawa, Issei Shinohara, Takahiro Furukawa, Masaya Kusunose, Takeshi Kokubu Source Type: research

Effect of aging on recruitment of tenogenic progenitor during tendon-to-bone healing in a rat rotator cuff repair model
Although elderly patients have a higher rate of retear afterrotator cuff (RC) repair, the effects of aging on the tendon-to-bone healingprocess remain unclear. We previously reported that scleraxis (Scx)-positivetenogenic cells may form tough, tendon-like tissue in a rat RC healing model.Here, we aimed to investigate the effects of aging on the recruitment oftenogenic cells and the mechanical strength at the repair site during tendon-tobonehealing after RC repair in rats. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 11, 2024 Category: Orthopaedics Authors: Shuntaro Tanimura, Takuya Tokunaga, Yuko Fukuma, Katsumasa Ideo, Tatsuki Karasugi, Takeshi Miyamoto Source Type: research