Nutrition, Phosphorus, and Keto-Analogues in Hemodialysis Patients: A Chinese Perspective
The optimal dietary protein requirements in maintenance hemodialysis (HD) patients and how to balance the treatments between the nutritional intervention and other approaches are still controversies among nephrologists. In China, excessive dietary intake, low dose of dialysis, and lack of non-calcium-containing phosphorus binders are the main causes of hyperphosphatemia among HD patients. If the daily protein intake reached the recommended dose of 1.2 g/kg body weight per the Kidney Disease Outcomes Quality Initiative guidelines, the net accumulation of phosphorus in patients receiving conventional thrice-weekly low-flux H...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Jing Chen Tags: ISRNM Proceedings Source Type: research

Effect of Low-Protein Diet Supplemented With Keto Acids on Progression of Chronic Kidney Disease
Hypoproteic diets are most often discussed for patients with chronic kidney disease (CKD) who do not receive dialysis.A very low-protein diet supplemented with ketoanalogues of essential amino acids (keto-diet) proved effective in ameliorating metabolic disturbances of advanced CKD and delaying the initiation of dialysis without deleterious effects on nutritional status.Several recent studies report that the keto-diet could also slow down the rate of decline in renal function, with better outcomes after the initiation of dialysis. Results of a single-center randomized controlled trial addressing the rate of CKD progression...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Liliana Garneata, Gabriel Mircescu Tags: ISRNM Proceedings Source Type: research

Obesity and Body Composition for Transplant Wait-List Candidacy—Challenging or Maintaining the BMI Limits?
Most kidney transplantation programs have a maximum body mass index (BMI) above which they will not place a patient on the active waiting list. However, obesity is common among patients with end-stage renal disease (ESRD), and weight loss is difficult, resulting in many patients being denied the opportunity to be considered for a transplant. BMI limits are in place because of data that outcomes are worse among obese transplant recipients than among those with lower BMI. However, the data to suggest that patient and graft survival are affected by obesity are not consistent, and obese patients with ESRD have better survival ...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Kirsten L. Johansen Tags: ISRNM Proceedings Source Type: research

Role of HDL Dysfunction in End-Stage Renal Disease: A Double-Edged Sword
End-stage renal disease (ESRD) is associated with a significant propensity for development of atherosclerosis and cardiovascular mortality. The atherogenic diathesis associated with ESRD is driven by inflammation, oxidative stress, and dyslipidemia. Reduced high-density lipoprotein cholesterol (HDL-C) level and high-density lipoprotein (HDL) dysfunction are the hallmarks of ESRD-related dyslipidemia. Clinical and laboratory studies have revealed that ESRD is associated with significantly reduced serum apolipoprotein A-I (ApoA-I) and HDL-C level as well as altered HDL composition. Furthermore, although ESRD is associated wi...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Hamid Moradi, Nosratola D. Vaziri, Moti L. Kashyap, Hamid M. Said, Kamyar Kalantar-Zadeh Tags: ISRNM Proceedings Source Type: research

Nutritional Evaluation of Patients Receiving Dialysis for the Management of Protein-Energy Wasting: What is Old and What is New?
Advances in the nutritional support of hospitalized patients in the early 1970s led to the recognition that tools were needed to evaluate the nutritional status of patients. The observation that malnutrition in patients receiving dialysis was associated with increased morbidity and mortality prompted many expert groups to develop nutritional scoring systems to be applied in these patients. Given the diverse and confusing terminologies that emerged from these publications, the International Society of Renal Nutritional and Metabolism convened an expert panel to recommend a new nomenclature and preferred methods to evaluate ...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Miguel C. Riella Tags: ISRNM Proceedings Source Type: research

World Renal Nutrition Week Congress: From Hawaii to Germany
In this issue of the journal, we present several important contributions that were presented in Honolulu, Hawaii, during the recent XVI International Congress on Nutrition and Metabolism in Renal Disease (ICRND) part of World Renal Nutrition Week (www.RenalNutritionWeek.com) June 25 to 30, 2012. The International Society for Renal Nutrition and Metabolism (ISRNM) has organized these Congresses since 1977 to promote research, education, and clinical use of nutrition and metabolism for the benefit of people with kidney disease. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Harold Franch, Kamyar Kalantar-Zadeh Tags: ISRNM Proceedings Source Type: research

Masthead
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Source Type: research

Early Versus Late Initiation of Dialysis and Nutrition: Does a Transition Mean a Change in Dietary Protein Intake?
Over the last 15 to 20 years, there has been an increasing trend toward early initiation of dialysis in patients with chronic kidney disease (CKD). This was based on early retrospective studies suggesting better clinical outcomes with an early start of dialysis, resulting in guidelines advocating an early start of dialysis in stage 5 CKD patients. However, this clinical practice came into question when more recent observational cohort studies reported higher mortality rates among CKD patients who started dialysis early. In this article, we review the current controversies relating to the timing of initiation of dialysis in...
Source: Journal of Renal Nutrition - March 25, 2013 Category: Urology & Nephrology Authors: Angela Yee-Moon Wang, Jean Woo Tags: ISRNM Proceedings Source Type: research

Systemic and Local Impact of Glucose and Glucose Degradation Products in Peritoneal Dialysis Solution
The main osmotic agent used in the peritoneal dialysis (PD) solution is glucose because of its great osmotic power, simple metabolism, and safety. Once into the systemic circulation, however, glucose can be a cause for metabolic complications including hyperglycemia, obesity, and dyslipidemia. The glucose absorbed from peritoneal cavity leads to insulin resistance and hyperglycemia, which is associated with oxidative stress. Long-term exposure of peritoneal membrane to glucose in PD solution also has local effects such as functional and structural changes leading to peritoneal membrane failure. Moreover, the intraperitonea...
Source: Journal of Renal Nutrition - March 18, 2013 Category: Urology & Nephrology Authors: Yong-Lim Kim, Jang-Hee Cho, Ji-Young Choi, Chan-Duck Kim, Sun-Hee Park Tags: ISRNM Proceedings Source Type: research

Assessing Glycemic Control in Diabetic Patients With Severe Nephropathy
Diabetes mellitus is the leading cause of chronic kidney disease and end-stage renal failure in westernized societies, including the United States. In addition to renal manifestations, complications of poorly controlled diabetes include accelerated atherosclerosis, congestive heart failure, neuropathy, and retinopathy. The estimated total cost of diabetes care in the United States was $174 billion in 2007—a number expected to increase markedly in the coming decades. Clinicians must be able to accurately recognize patients with poor glycemic control to have opportunities to intensify treatment and potentially reduce h...
Source: Journal of Renal Nutrition - March 18, 2013 Category: Urology & Nephrology Authors: Todd W. Robinson, Barry I. Freedman Tags: ISRNM Proceedings Source Type: research

Soy Milk Consumption and Blood Pressure Among Type 2 Diabetic Patients With Nephropathy
Conclusions: Soy milk consumption was associated with better blood pressure control among diabetic patients with nephropathy. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 15, 2013 Category: Urology & Nephrology Authors: Maryam Sadat Miraghajani, Mojgan Mortazavi Najafabadi, Pamela J. Surkan, Ahmad Esmaillzadeh, Maryam Mirlohi, Leila Azadbakht Tags: Original Research Source Type: research

Nutritional Evaluation and Management of AKI Patients
Protein-energy wasting is common in patients with acute kidney injury (AKI) and represents a major negative prognostic factor. Nutritional support as parenteral and/or enteral nutrition is frequently needed because the early phases of this are often a highly catabolic state, although the optimal nutritional requirements and nutrient intake composition remain a partially unresolved issue. Nutrient needs of patients with AKI are highly heterogeneous, depending on different pathogenetic mechanisms, catabolic rate, acute and chronic comorbidities, and renal replacement therapy (RRT) modalities. Thus, quantitative and qualitati...
Source: Journal of Renal Nutrition - March 13, 2013 Category: Urology & Nephrology Authors: Enrico Fiaccadori, Umberto Maggiore, Aderville Cabassi, Santo Morabito, Giuseppe Castellano, Giuseppe Regolisti Tags: ISRNM Proceedings Source Type: research

Autonomic Function is Associated With Health-Related Quality of Life in Patients With End-Stage Renal Disease: A Case-Control Study
Conclusions: Impaired autonomic function is significantly associated with fatigue and impaired QOL in dialysis patients. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 1, 2013 Category: Urology & Nephrology Authors: Hisako Fujii, Hidenori Koyama, Sanae Fukuda, Hidekichi Tokai, Seiki Tajima, Jun-ichi Koizumi, Kouji Yamaguti, Hirohiko Kuratsune, Yasuyoshi Watanabe, Yoshinobu Hirayama, Tetsuo Shoji, Masaaki Inaba, Yoshiki Nishizawa Tags: Original Research Source Type: research

The Effect of Ergocalciferol on Uremic Pruritus Severity: A Randomized Controlled Trial
Conclusion: In conclusion, we did not find ergocalciferol to be effective for the treatment of uremic pruritus. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 1, 2013 Category: Urology & Nephrology Authors: Shayan Shirazian, Mary Schanler, Shuba Shastry, Shaunak Dwivedi, Maanvi Kumar, Kathleen Rice, Nobuyuki Miyawaki, Samiran Ghosh, Steven Fishbane Tags: Original Research Source Type: research

Dietary Protein Restriction for Renal Patients: Don't Forget Protein-Free Foods
Conclusions: The use of these products may help in reducing protein, phosphorus, and sodium intake while supplying an adequate energy intake, which represents the basis for a nutritionally safe and successful dietary treatment of advanced CKD patients. Manufacturers and food technology should make more efforts to finding new solutions to improve the taste and texture of protein-free products. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 22, 2013 Category: Urology & Nephrology Authors: Claudia D’Alessandro, Andrea Rossi, Maurizio Innocenti, Guido Ricchiuti, Laura Bozzoli, Giulietta Sbragia, Mario Meola, Adamasco Cupisti Tags: Research Briefs Source Type: research

Author's Reply to Letter to the Editor
I appreciate and read with interest the Letter to Editor by Jackson entitled “Moving the Issue of Renal Dietitian Forward: An International Perspective,” which is a response to my article “Moving the Issue of Renal Nutrition Forward,” in the September 2012 issue of the Journal of Renal Nutrition. The letter presents an opportunity to make a few brief observations. First, the involvement of dietitians in Australia with increasing the number of patients using home dialysis modalities is admirable and something that their international counterparts can perhaps strive to replicate. Along with having sur...
Source: Journal of Renal Nutrition - February 22, 2013 Category: Urology & Nephrology Authors: William A. Wolfe Tags: Letters to the Editor Source Type: research

Table of Contents
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Editorial Board
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Masthead
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Thank You to Our Reviewers
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Acknowledgments Source Type: research

March Meeting Announcements
March 9-12, 2013 Annual Dialysis Conference (33rd Annual Dialysis Conference/19th International Symposium on Hemodialysis/24th Annual Symposium on Pediatric Dialysis), Washington State Convention & Trade Center, Seattle, WA. Visit http://som.missouri.edu/dialysis or call (573) 882-4105. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Announcements Source Type: research

Hemodialysis (HD) Patients with Liver Disease: Intradialytic Parenteral Nutrition (IDPN)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Concurrent Validation of Subjective Global Assessment (SGA) in Nondialysis-Dependent Chronic Kidney Disease Patients (NDD-CKD)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

The “Phosphorus Olympics”: A Self-Management Approach for Enhancing Phosphorus Education in a Multi-Site Dialysis Program
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Sarcopenia and Dynapenia are Associated with Worse Quality of Life in Elderly HD Patients
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Sarcopenia, Dynapenia and Muscle Atrophy: Are They Associated with Worse Clinical Condition in Elderly Hemodialysis Patients?
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Supports and Barriers of Registered Dietitians (RDs) in Using a Chronic Kidney Disease (CKD) Guideline
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Relationship Between Phosphorus Levels, Race and Age in Chronic Kidney Disease (CKD) Patients on Hemodialysis (HD)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Renal Dietitian’s Subjective Assessments Of Dietary Intakes Show Differences Compared to NKF-KDOQI Guidelines: A Pilot Study
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

A Feasibility Study to Test the Effect of Online Nutrition Care Algorithm vs. Additional Patient Care Time on Patient Care and Outcomes
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

The Benefit of In-Center Oral Protein Supplementation on Hemodialysis Patients
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Effects of Changing From Conventional To Home HD, The Irish Experience
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Aerobic Exercise: An Effective Intervention to Reduce Visceral Fat in Obese Men with CKD
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Diagnosis of Sarcopenia in Chronic Kidney Disease: Comparison of 3 Methods
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

National Kidney Foundation 2013 Spring Clinical Meetings Abstracts April 2-6, 2013
Diagnosis of Sarcopenia in Chronic Kidney Disease: Comparison of 3 Methods (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM)
Protein-energy wasting (PEW), a term proposed by the International Society of Renal Nutrition and Metabolism (ISRNM), refers to the multiple nutritional and catabolic alterations that occur in chronic kidney disease (CKD) and associate with morbidity and mortality. To increase awareness, identify research needs, and provide the basis for future work to understand therapies and consequences of PEW, ISRNM provides this consensus statement of current knowledge on the etiology of PEW syndrome in CKD. Although insufficient food intake (true undernutrition) due to poor appetite and dietary restrictions contribute, other highly p...
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Authors: Juan Jesús Carrero, Peter Stenvinkel, Lilian Cuppari, T. Alp Ikizler, Kamyar Kalantar-Zadeh, George Kaysen, William E. Mitch, S. Russ Price, Christoph Wanner, Angela Y.M. Wang, Pieter ter Wee, Harold A. Franch Tags: Review Article Source Type: research

Spot Urine Tests in Predicting 24-Hour Urine Sodium Excretion in Asian Patients
Conclusion: Spot urine sodium can help monitor a patient's sodium intake when used in the derived 5-variable equation. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 11, 2013 Category: Urology & Nephrology Authors: Srinivas Subramanian, Boon Wee Teo, Qi Chun Toh, Yun Yin Koh, Jialiang Li, Sunil Sethi, Evan J.C. Lee Tags: Original Research Source Type: research

The Prevalence of Phosphorus-Containing Food Additives in Top-Selling Foods in Grocery Stores
Conclusion: Phosphorus additives are common in best-selling processed groceries and contribute significantly to their phosphorus content. Moreover, phosphorus additive foods are less costly than phosphorus additive-free foods. As a result, persons with chronic kidney disease may purchase these popular low-cost groceries and unknowingly increase their intake of highly bioavailable phosphorus. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 11, 2013 Category: Urology & Nephrology Authors: Janeen B. León, Catherine M. Sullivan, Ashwini R. Sehgal Tags: Original Research Source Type: research

Strategies for Setting Medical Nutrition Therapy Priorities for Patients With Stage 3 and 4 Chronic Kidney Disease
The provision of medical nutrition therapy (MNT) for patients with early chronic kidney disease (CKD) has become more common since Medicare began reimbursing for this service in January 2002. This is good news for patients. It has been demonstrated that nutrition care for predialysis patients can improve survival during the first year of dialysis. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - January 21, 2013 Category: Urology & Nephrology Authors: Lynn Munson Tags: Patient Education Source Type: research

Is Going Gluten Free the Next Fad Diet?
Gluten-free dieting has gained considerable popularity. Once regarded as a niche product that was of interest only to individuals who could not tolerate gluten, gluten-free products have been transformed quickly into a mainstream sensation. According to a 2012 report, the US gluten-free market reached an estimated $4.2 billion in retail sales. The consumer survey by Packaged Facts shows that 18% of adults are buying or consuming food products tagged as gluten free. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - January 14, 2013 Category: Urology & Nephrology Authors: Pamela S. Kent Tags: Product Update Source Type: research

Let Them Eat During Dialysis: An Overlooked Opportunity to Improve Outcomes in Maintenance Hemodialysis Patients
In individuals with chronic kidney disease, surrogates of protein-energy wasting, including a relatively low serum albumin and fat or muscle wasting, are by far the strongest death risk factor compared with any other condition. There are data to indicate that hypoalbuminemia responds to nutritional interventions, which may save lives in the long run. Monitored, in-center provision of high-protein meals and/or oral nutritional supplements during hemodialysis is a feasible, inexpensive, and patient-friendly strategy despite concerns such as postprandial hypotension, aspiration risk, infection control and hygiene, dialysis st...
Source: Journal of Renal Nutrition - January 11, 2013 Category: Urology & Nephrology Authors: Kamyar Kalantar-Zadeh, T. Alp Ikizler Tags: Review Article Source Type: research

Insulin Resistance and Protein Metabolism in Chronic Hemodialysis Patients
Objective: Loss of lean body mass (sarcopenia) is associated with increased morbidity and mortality in patients receiving chronic hemodialysis (CHD). Insulin resistance (IR), which is highly prevalent in patients receiving CHD, has been proposed to play a critical role in the development of sarcopenia. The aim of this study was to examine the effect of IR on amino acid metabolism in patients receiving CHD.Design: This was a cross-sectional study.Subjects: The study included 12 prevalent (i.e., patients that have been on dialysis for more than 90 days) African American patients receiving CHD.Methods: IR was measured as gluc...
Source: Journal of Renal Nutrition - November 29, 2012 Category: Urology & Nephrology Authors: Serpil M. Deger, Mary B. Sundell, Edward D. Siew, Phyllis Egbert, Charles D. Ellis, Feng Sha, T. Alp Ikizler, Adriana M. Hung Tags: Original Research Source Type: research

Can Renal Nutrition Education Improve Adherence to a Low-Protein Diet in Patients With Stages 3 to 5 Chronic Kidney Disease?
This study included adult patients with an estimated glomerular filtration rate (eGFR) (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - November 29, 2012 Category: Urology & Nephrology Authors: Juliana Giglio Paes-Barreto, Maria Inês Barreto Silva, Abdul Rashid Qureshi, Rachel Bregman, Vicente Faria Cervante, Juan Jesús Carrero, Carla Maria Avesani Tags: Original Research Source Type: research

Moving the Issue of Renal Dietitian Staffing Forward: An International Perspective
Nutrition intervention in renal disease has long been recognized as important, with dietitians showing enthusiasm and resolve in furthering advancing nutritional care of renal patients, evidenced by progression from early use of low-protein diets in the 1800s to rigorously abstracted clinical practice guidelines. Advancements in the evidence base have allowed for the development of increasingly sophisticated care standards that have emerged globally in the last decade. Key features are the focus on the detection, prevention, and treatment of malnutrition, specifically noting the fundamental requirement of access to a ...
Source: Journal of Renal Nutrition - November 9, 2012 Category: Urology & Nephrology Authors: Suzy Jackson Tags: Letters to the Editor Source Type: research

Limb/Trunk Lean Mass Ratio as a Risk Factor for Mortality in Peritoneal Dialysis Patients
Conclusions: LTLM is associated with other lean mass indices, nutritional status, and mortality in CAPD patients. Therefore, LTLM is a novel marker that is useful for the prediction of the nutritional status and mortality in patients with CAPD. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - November 9, 2012 Category: Urology & Nephrology Authors: Seok Hui Kang, Jong Won Park, Kyung Woo Yoon, Jun Young Do Tags: Original Research Source Type: research

Effects of Zinc Supplementation on Antioxidant Status and Lipid Peroxidation in Hemodialysis Patients
This study was designed to determine the effects of zinc supplementation on oxidative stress in hemodialysis (HD) patients through evaluating total antioxidant capacity (TAC), whole blood glutathione peroxidase (GSH) level, superoxide dismutase (SOD) activity, and malondialdehyde (MDA) level.Design and Setting: Double-blinded randomized controlled trialfrom October 2006 to December 2007 at Tabriz Imam Khomeini Hospital.Subjects: Sixty-five HD patients were randomly enrolled into 2 groups.Intervention: Patients received placebo in group A and zinc (100 mg/day) in group B for 2 months. After a washout period for 2 month...
Source: Journal of Renal Nutrition - November 8, 2012 Category: Urology & Nephrology Authors: Mohammad Mazani, Hassan Argani, Nadereh Rashtchizadeh, Amir Ghorbanihaghjo, Amir Hamdi, Mehrdad Asghari Estiar, Nariman Nezami Tags: Original Research Source Type: research

Urinary Phosphate Excretion and Fibroblast Growth Factor 23 in Chronic Kidney Disease
We read with great interest the paper of Houston and colleagues entitled “Associations of Dietary Phosphorus Intake, Urinary Phosphate Excretion, and Fibroblast Growth Factor 23 With Vascular Stiffness in Chronic Kidney Disease”. In a cross-sectional study, the authors studied 74 adult chronic kidney disease (CKD) patients (mean age 64 years, mean creatinine clearance 51 ± 19 mL/min, 64% males, 12% black, 29% diabetic, and 30% received calcium supplements) and declared that fibroblast growth factor 23 (FGF-23) was associated with serum phosphate (r = 0.24, P
Source: Journal of Renal Nutrition - November 5, 2012 Category: Urology & Nephrology Authors: Biagio R. Di Iorio, Serena Torraca, Maria Luisa Sirico, Lucia Di Micco Tags: Letter to the Editor Source Type: research

Effects of Urate-Lowering Therapy in Hyperuricemia on Slowing the Progression of Renal Function: A Meta-Analysis
Uric acid (UA) is generally regarded as an independent risk factor for poor prognosis of patients with kidney disease. However, urate-lowering therapy (ULT) in asymptomatic hyperuricemia is conservative. Whether the beneficial effect on renal function can be achieved by lowering UA remains uncertain. A compound search for randomized controlled trials was conducted in databases consisting of MEDLINE, EMBASE, the Cochrane Library, the Chinese Biomedical Literature Database, and Chinese Science and Technology periodical databases. Two investigators independently screened these studies, assessed the included trials, and extrac...
Source: Journal of Renal Nutrition - November 5, 2012 Category: Urology & Nephrology Authors: Huan Wang, Yong Wei, Xianglei Kong, Dongmei Xu Tags: Review Source Type: research