Table of Contents
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Editorial Board
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Food, Food Components, and Botanicals Affecting Drug Metabolism in Transplantation
In 2006, the US Food and Drug Administration (FDA) issued the draft guidance document “Complementary and Alternative Medicine Products and Their Regulation by the Food and Drug Administration” partly because of the increasingly widespread use of complementary and alternative medicine (CAM) providers and CAM products in the United States. CAM products are subject to regulation in the United States. The terms complementary and alternative represent 2 categories—1 complements traditional medicine and the other is an alternative to traditional medicine. One of the 4 domains of CAM includes biologically based ...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Linda W. Moore Tags: Patient Education Source Type: research

Gluten-Free Protein Bar Options
Celiac disease is an autoimmune disorder that is triggered by the ingestion of gluten. The prevalence of celiac disease in the United States is 1 in 141 persons. With advances in diagnostic testing, more patients are being diagnosed with this disease. On the other hand, many consumers are jumping on the bandwagon and using gluten-free products because they may believe that these products are healthier or that they may help them with weight loss. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Laura Bishop Tags: Product Update Source Type: research

May Meeting Announcements
May 4-7, 2013 American Society of Pediatric Nephrology 2013 ASPN/PAS Annual Meeting, Washington, DC. Visit http://www.aspneph.com or call 281-419-0052. May 15-17, 2013 American Society of Hypertension 2013 Annual Scientific Meeting, San Francisco Marriott, San Francisco, California. Visit www.ash-us.org or call 800-292-8130. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Tags: Announcements Source Type: research

Does More Frequent Hemodialysis Provide Dietary Freedom?
Proponents of more frequent hemodialysis have suggested that this modality may improve nutritional status. A review of trials performed in the past 10 years was carried out to substantiate this claim. Three daily hemodialysis trials and 5 nocturnal hemodialysis trials were identified. More frequent hemodialysis did not appear to consistently improve serum albumin levels, weight after dialysis, protein catabolic rate, or protein or energy intake as measured by food diaries, except in 1 study with an average duration of conventional dialysis of 9.8 years before patients were switched to short daily hemodialysis and a mean fo...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Michael V. Rocco Tags: ISRNM Proceedings Source Type: research

Fibroblast Growth Factor 23, Klotho, and Disordered Mineral Metabolism in Chronic Kidney Disease: Unraveling the Intricate Tapestry of Events and Implications for Therapy
Fibroblast growth factor 23 (FGF23) and Klotho play key roles, along with serum phosphate and parathyroid hormone (PTH), in disordered mineral metabolism in chronic kidney disease (CKD). Through independent and combined effects on renal phosphorus and vitamin D metabolism, alterations in FGF23 and Klotho expression are essential for maintaining mineral homeostasis in kidney disease. However, increasing evidence showing that disturbances in FGF23 and Klotho expression produce direct cardiovascular and renal toxicity has accelerated interest in therapies that directly target these hormones in the interest of improving outcom...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Orlando M. Gutiérrez Tags: ISRNM Proceedings Source Type: research

Protein Energy Wasting and Transplantation
In patients with advanced renal failure or those undergoing dialysis, protein energy wasting (PEW) is a frequently occurring complication that is associated with increased cardiovascular morbidity and mortality. Fewer data are available for patients after transplantation. In this article, the available data on nutritional status after kidney transplantation is reviewed. It was also found that signs of PEW and microinflammation in patients undergoing kidney transplantation are associated with both impaired transplantation outcomes and decreased patient survival. Data are lacking on nutritional support and outcomes after tra...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Piet M. ter Wee Tags: ISRNM Proceedings Source Type: research

Traditional and Novel Dietary Interventions for Preventing Progression of Chronic Kidney Disease
This article reviews the various interventions using such a strategy to prevent or slow the progression of CKD, with special focus on recent advances in this field. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Csaba P. Kovesdy Tags: ISRNM Proceedings Source Type: research

Nutritional Issues in Peritoneal Dialysis Patients: How Do They Differ From That of Patients Undergoing Hemodialysis?
In conclusion, it is important to consider these unique nutritional considerations when providing care to patients undergoing PD. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Rajnish Mehrotra Tags: ISRNM Proceedings Source Type: research

Implications and Importance of Skeletal Muscle Mass in Estimating Glomerular Filtration Rate at Dialysis Initiation
There is a trend toward “early” initiation of dialysis for renal replacement therapy. However, several observational studies showed an association of increased mortality at higher estimated glomerular filtration rate (eGFR) at dialysis initiation. This surprising result is due to errors in estimation of glomerular filtration rate (GFR). In malnourished patients with low muscle mass, serum-creatinine-based equations overestimate GFR. In patients with higher muscle mass, these equations underestimate GFR. This spurious association of higher prevalence of malnutrition in patients with higher eGFR compared with tho...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Tahir Zaman, Rebecca Filipowicz, Srinivasan Beddhu Tags: ISRNM Proceedings Source Type: research

Dietary Sodium: A Therapeutic Target in the Treatment of Hypertension and CKD
Interventional trials of dietary sodium reduction have demonstrated improvements in blood pressure, cardiovascular events, and chronic kidney disease (CKD). Furthermore, public health initiatives to reduce population sodium intake in Finland and Japan have shown similar benefit in blood pressure and stroke reduction. Recent follow-up data from large cohort trials that suggest increased mortality among individuals with lower urinary sodium excretion have generated controversy regarding the optimal sodium intake. This paper reviews the evidence for the reduction of dietary sodium to prevent and manage chronic diseases, inclu...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Sarah Sanghavi, Joseph A. Vassalotti Tags: ISRNM Proceedings Source Type: research

Nutrition, Phosphorus, and Keto-Analogues in Hemodialysis Patients: A Chinese Perspective
The optimal dietary protein requirements in maintenance hemodialysis (HD) patients and how to balance the treatments between the nutritional intervention and other approaches are still controversies among nephrologists. In China, excessive dietary intake, low dose of dialysis, and lack of non-calcium-containing phosphorus binders are the main causes of hyperphosphatemia among HD patients. If the daily protein intake reached the recommended dose of 1.2 g/kg body weight per the Kidney Disease Outcomes Quality Initiative guidelines, the net accumulation of phosphorus in patients receiving conventional thrice-weekly low-flux H...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Jing Chen Tags: ISRNM Proceedings Source Type: research

Effect of Low-Protein Diet Supplemented With Keto Acids on Progression of Chronic Kidney Disease
Hypoproteic diets are most often discussed for patients with chronic kidney disease (CKD) who do not receive dialysis.A very low-protein diet supplemented with ketoanalogues of essential amino acids (keto-diet) proved effective in ameliorating metabolic disturbances of advanced CKD and delaying the initiation of dialysis without deleterious effects on nutritional status.Several recent studies report that the keto-diet could also slow down the rate of decline in renal function, with better outcomes after the initiation of dialysis. Results of a single-center randomized controlled trial addressing the rate of CKD progression...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Liliana Garneata, Gabriel Mircescu Tags: ISRNM Proceedings Source Type: research

Obesity and Body Composition for Transplant Wait-List Candidacy—Challenging or Maintaining the BMI Limits?
Most kidney transplantation programs have a maximum body mass index (BMI) above which they will not place a patient on the active waiting list. However, obesity is common among patients with end-stage renal disease (ESRD), and weight loss is difficult, resulting in many patients being denied the opportunity to be considered for a transplant. BMI limits are in place because of data that outcomes are worse among obese transplant recipients than among those with lower BMI. However, the data to suggest that patient and graft survival are affected by obesity are not consistent, and obese patients with ESRD have better survival ...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Kirsten L. Johansen Tags: ISRNM Proceedings Source Type: research

Role of HDL Dysfunction in End-Stage Renal Disease: A Double-Edged Sword
End-stage renal disease (ESRD) is associated with a significant propensity for development of atherosclerosis and cardiovascular mortality. The atherogenic diathesis associated with ESRD is driven by inflammation, oxidative stress, and dyslipidemia. Reduced high-density lipoprotein cholesterol (HDL-C) level and high-density lipoprotein (HDL) dysfunction are the hallmarks of ESRD-related dyslipidemia. Clinical and laboratory studies have revealed that ESRD is associated with significantly reduced serum apolipoprotein A-I (ApoA-I) and HDL-C level as well as altered HDL composition. Furthermore, although ESRD is associated wi...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Hamid Moradi, Nosratola D. Vaziri, Moti L. Kashyap, Hamid M. Said, Kamyar Kalantar-Zadeh Tags: ISRNM Proceedings Source Type: research

Nutritional Evaluation of Patients Receiving Dialysis for the Management of Protein-Energy Wasting: What is Old and What is New?
Advances in the nutritional support of hospitalized patients in the early 1970s led to the recognition that tools were needed to evaluate the nutritional status of patients. The observation that malnutrition in patients receiving dialysis was associated with increased morbidity and mortality prompted many expert groups to develop nutritional scoring systems to be applied in these patients. Given the diverse and confusing terminologies that emerged from these publications, the International Society of Renal Nutritional and Metabolism convened an expert panel to recommend a new nomenclature and preferred methods to evaluate ...
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Miguel C. Riella Tags: ISRNM Proceedings Source Type: research

World Renal Nutrition Week Congress: From Hawaii to Germany
In this issue of the journal, we present several important contributions that were presented in Honolulu, Hawaii, during the recent XVI International Congress on Nutrition and Metabolism in Renal Disease (ICRND) part of World Renal Nutrition Week (www.RenalNutritionWeek.com) June 25 to 30, 2012. The International Society for Renal Nutrition and Metabolism (ISRNM) has organized these Congresses since 1977 to promote research, education, and clinical use of nutrition and metabolism for the benefit of people with kidney disease. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Authors: Harold Franch, Kamyar Kalantar-Zadeh Tags: ISRNM Proceedings Source Type: research

Masthead
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 23, 2013 Category: Urology & Nephrology Source Type: research

Early Versus Late Initiation of Dialysis and Nutrition: Does a Transition Mean a Change in Dietary Protein Intake?
Over the last 15 to 20 years, there has been an increasing trend toward early initiation of dialysis in patients with chronic kidney disease (CKD). This was based on early retrospective studies suggesting better clinical outcomes with an early start of dialysis, resulting in guidelines advocating an early start of dialysis in stage 5 CKD patients. However, this clinical practice came into question when more recent observational cohort studies reported higher mortality rates among CKD patients who started dialysis early. In this article, we review the current controversies relating to the timing of initiation of dialysis in...
Source: Journal of Renal Nutrition - March 25, 2013 Category: Urology & Nephrology Authors: Angela Yee-Moon Wang, Jean Woo Tags: ISRNM Proceedings Source Type: research

Systemic and Local Impact of Glucose and Glucose Degradation Products in Peritoneal Dialysis Solution
The main osmotic agent used in the peritoneal dialysis (PD) solution is glucose because of its great osmotic power, simple metabolism, and safety. Once into the systemic circulation, however, glucose can be a cause for metabolic complications including hyperglycemia, obesity, and dyslipidemia. The glucose absorbed from peritoneal cavity leads to insulin resistance and hyperglycemia, which is associated with oxidative stress. Long-term exposure of peritoneal membrane to glucose in PD solution also has local effects such as functional and structural changes leading to peritoneal membrane failure. Moreover, the intraperitonea...
Source: Journal of Renal Nutrition - March 18, 2013 Category: Urology & Nephrology Authors: Yong-Lim Kim, Jang-Hee Cho, Ji-Young Choi, Chan-Duck Kim, Sun-Hee Park Tags: ISRNM Proceedings Source Type: research

Assessing Glycemic Control in Diabetic Patients With Severe Nephropathy
Diabetes mellitus is the leading cause of chronic kidney disease and end-stage renal failure in westernized societies, including the United States. In addition to renal manifestations, complications of poorly controlled diabetes include accelerated atherosclerosis, congestive heart failure, neuropathy, and retinopathy. The estimated total cost of diabetes care in the United States was $174 billion in 2007—a number expected to increase markedly in the coming decades. Clinicians must be able to accurately recognize patients with poor glycemic control to have opportunities to intensify treatment and potentially reduce h...
Source: Journal of Renal Nutrition - March 18, 2013 Category: Urology & Nephrology Authors: Todd W. Robinson, Barry I. Freedman Tags: ISRNM Proceedings Source Type: research

Soy Milk Consumption and Blood Pressure Among Type 2 Diabetic Patients With Nephropathy
Conclusions: Soy milk consumption was associated with better blood pressure control among diabetic patients with nephropathy. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 15, 2013 Category: Urology & Nephrology Authors: Maryam Sadat Miraghajani, Mojgan Mortazavi Najafabadi, Pamela J. Surkan, Ahmad Esmaillzadeh, Maryam Mirlohi, Leila Azadbakht Tags: Original Research Source Type: research

Nutritional Evaluation and Management of AKI Patients
Protein-energy wasting is common in patients with acute kidney injury (AKI) and represents a major negative prognostic factor. Nutritional support as parenteral and/or enteral nutrition is frequently needed because the early phases of this are often a highly catabolic state, although the optimal nutritional requirements and nutrient intake composition remain a partially unresolved issue. Nutrient needs of patients with AKI are highly heterogeneous, depending on different pathogenetic mechanisms, catabolic rate, acute and chronic comorbidities, and renal replacement therapy (RRT) modalities. Thus, quantitative and qualitati...
Source: Journal of Renal Nutrition - March 13, 2013 Category: Urology & Nephrology Authors: Enrico Fiaccadori, Umberto Maggiore, Aderville Cabassi, Santo Morabito, Giuseppe Castellano, Giuseppe Regolisti Tags: ISRNM Proceedings Source Type: research

Autonomic Function is Associated With Health-Related Quality of Life in Patients With End-Stage Renal Disease: A Case-Control Study
Conclusions: Impaired autonomic function is significantly associated with fatigue and impaired QOL in dialysis patients. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 1, 2013 Category: Urology & Nephrology Authors: Hisako Fujii, Hidenori Koyama, Sanae Fukuda, Hidekichi Tokai, Seiki Tajima, Jun-ichi Koizumi, Kouji Yamaguti, Hirohiko Kuratsune, Yasuyoshi Watanabe, Yoshinobu Hirayama, Tetsuo Shoji, Masaaki Inaba, Yoshiki Nishizawa Tags: Original Research Source Type: research

The Effect of Ergocalciferol on Uremic Pruritus Severity: A Randomized Controlled Trial
Conclusion: In conclusion, we did not find ergocalciferol to be effective for the treatment of uremic pruritus. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - March 1, 2013 Category: Urology & Nephrology Authors: Shayan Shirazian, Mary Schanler, Shuba Shastry, Shaunak Dwivedi, Maanvi Kumar, Kathleen Rice, Nobuyuki Miyawaki, Samiran Ghosh, Steven Fishbane Tags: Original Research Source Type: research

Dietary Protein Restriction for Renal Patients: Don't Forget Protein-Free Foods
Conclusions: The use of these products may help in reducing protein, phosphorus, and sodium intake while supplying an adequate energy intake, which represents the basis for a nutritionally safe and successful dietary treatment of advanced CKD patients. Manufacturers and food technology should make more efforts to finding new solutions to improve the taste and texture of protein-free products. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 22, 2013 Category: Urology & Nephrology Authors: Claudia D’Alessandro, Andrea Rossi, Maurizio Innocenti, Guido Ricchiuti, Laura Bozzoli, Giulietta Sbragia, Mario Meola, Adamasco Cupisti Tags: Research Briefs Source Type: research

Author's Reply to Letter to the Editor
I appreciate and read with interest the Letter to Editor by Jackson entitled “Moving the Issue of Renal Dietitian Forward: An International Perspective,” which is a response to my article “Moving the Issue of Renal Nutrition Forward,” in the September 2012 issue of the Journal of Renal Nutrition. The letter presents an opportunity to make a few brief observations. First, the involvement of dietitians in Australia with increasing the number of patients using home dialysis modalities is admirable and something that their international counterparts can perhaps strive to replicate. Along with having sur...
Source: Journal of Renal Nutrition - February 22, 2013 Category: Urology & Nephrology Authors: William A. Wolfe Tags: Letters to the Editor Source Type: research

Table of Contents
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Editorial Board
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Masthead
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Frontmatter Source Type: research

Thank You to Our Reviewers
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Acknowledgments Source Type: research

March Meeting Announcements
March 9-12, 2013 Annual Dialysis Conference (33rd Annual Dialysis Conference/19th International Symposium on Hemodialysis/24th Annual Symposium on Pediatric Dialysis), Washington State Convention & Trade Center, Seattle, WA. Visit http://som.missouri.edu/dialysis or call (573) 882-4105. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: Announcements Source Type: research

Hemodialysis (HD) Patients with Liver Disease: Intradialytic Parenteral Nutrition (IDPN)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Concurrent Validation of Subjective Global Assessment (SGA) in Nondialysis-Dependent Chronic Kidney Disease Patients (NDD-CKD)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

The “Phosphorus Olympics”: A Self-Management Approach for Enhancing Phosphorus Education in a Multi-Site Dialysis Program
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Sarcopenia and Dynapenia are Associated with Worse Quality of Life in Elderly HD Patients
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Sarcopenia, Dynapenia and Muscle Atrophy: Are They Associated with Worse Clinical Condition in Elderly Hemodialysis Patients?
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Supports and Barriers of Registered Dietitians (RDs) in Using a Chronic Kidney Disease (CKD) Guideline
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Relationship Between Phosphorus Levels, Race and Age in Chronic Kidney Disease (CKD) Patients on Hemodialysis (HD)
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Renal Dietitian’s Subjective Assessments Of Dietary Intakes Show Differences Compared to NKF-KDOQI Guidelines: A Pilot Study
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

A Feasibility Study to Test the Effect of Online Nutrition Care Algorithm vs. Additional Patient Care Time on Patient Care and Outcomes
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

The Benefit of In-Center Oral Protein Supplementation on Hemodialysis Patients
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Effects of Changing From Conventional To Home HD, The Irish Experience
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Aerobic Exercise: An Effective Intervention to Reduce Visceral Fat in Obese Men with CKD
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

Diagnosis of Sarcopenia in Chronic Kidney Disease: Comparison of 3 Methods
(Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research

National Kidney Foundation 2013 Spring Clinical Meetings Abstracts April 2-6, 2013
Diagnosis of Sarcopenia in Chronic Kidney Disease: Comparison of 3 Methods (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - February 21, 2013 Category: Urology & Nephrology Tags: National Kidney Foundation 2013 Spring Clinical Meetings Abstracts Source Type: research