Journal of Psychiatry and Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Reviving: restoring depression-like behaviour through glial cell-derived neurotrophic factor treatment in the medial prefrontal cortex
CONCLUSION: Our findings support a positive effect of exogenous GDNF on synaptic plasticity, mediated by DRD1 signalling in the mPFC, which could facilitate depression remission in Parkinson disease.PMID:38302136 | PMC:PMC10843345 | DOI:10.1503/jpn.230079 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 1, 2024 Category: Psychiatry Authors: Yehao Liu Xiaoyu Zhou Ke Xue Ruiao Sun Yan Tang Chuanxi Tang Source Type: research

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia
CONCLUSION: We found global HPTM alterations consistent with an aberrantly permissive epigenome in schizophrenia. Further studies to elucidate the significance of enhanced permissive HPTMs in schizophrenia and its association with the mechanism of action of antipsychotic drugs are encouraged.PMID:38302137 | PMC:PMC10843339 | DOI:10.1503/jpn.230054 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 1, 2024 Category: Psychiatry Authors: Oihane Mart ínez-Peula Benito Morentin Luis F Callado J Javier Meana Guadalupe Rivero Alfredo Ramos-Miguel Source Type: research

Different levels of prepulse inhibition among patients with first-episode schizophrenia, bipolar disorder and major depressive disorder
CONCLUSION: The level of prepulse inhibition among patients with first-episode schizophrenia was the lowest, with levels among patients with BD, patients with MDD and healthy controls increasingly higher. The PSS-PPI paradigm was more effective than PSC-PPI to recognize deficits in prepulse inhibition. These results provide a basis for further research on biological indicators that can assist differential diagnoses in psychosis.PMID:38238035 | PMC:PMC10803101 | DOI:10.1503/jpn.230083 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - January 18, 2024 Category: Psychiatry Authors: Yue Sun Qijing Bo Zhen Mao Qing Tian Fang Dong Liang Li Chuanyue Wang Source Type: research

State- and trait-related dysfunctions in bipolar disorder across different mood states: a graph theory study
CONCLUSION: Mood-specific whole-brain network metrics could serve as potential biomarkers in BD for transitions between mood states. Moreover, these findings contribute to evidence of trait-related frontolimbic circuit irregularities, shedding light on underlying pathophysiological mechanisms in BD.PMID:38238036 | PMC:PMC10803102 | DOI:10.1503/jpn.230069 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - January 18, 2024 Category: Psychiatry Authors: Yifan Chen Pengfei Zhao Chunyu Pan Miao Chang Xizhe Zhang Jia Duan Yange Wei Yanqing Tang Fei Wang Source Type: research

Meta-analysis of cortical thickness reduction in adult schizophrenia
CONCLUSION: The meta-analysis suggested robust cortical thickness reduction in the IFG, insula and STG among adult patients with schizophrenia, particularly in those with chronic schizophrenia. The results provide useful insights to understanding the underlying pathophysiology of schizophrenia.PMID:38123240 | PMC:PMC10743639 | DOI:10.1503/jpn.230081 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - December 20, 2023 Category: Psychiatry Authors: Shilin Sun Shu Xiao Zixuan Guo Jiaying Gong Guixian Tang Li Huang Ying Wang Source Type: research

Missed diagnosis of longstanding narcolepsy
J Psychiatry Neurosci. 2023 Dec 20;48(6):E472-E473. doi: 10.1503/jpn.230097. Print 2023 Nov-Dec.NO ABSTRACTPMID:38123241 | PMC:PMC10743625 | DOI:10.1503/jpn.230097 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - December 20, 2023 Category: Psychiatry Authors: Craig Chepke Source Type: research

Abnormal interhemispheric functional cooperation in schizophrenia follows the neurotransmitter profiles
CONCLUSION: Regional abnormalities in interhemispheric cooperation may contribute to the clinical symptoms of schizophrenia. These CFH abnormalities may be associated with dysfunction in neurotransmitter systems strongly implicated in schizophrenia.PMID:38123242 | PMC:PMC10743641 | DOI:10.1503/jpn.230037 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - December 20, 2023 Category: Psychiatry Authors: Kongliang He Qiang Hua Qianqian Li Yan Zhang Xiaoqing Yao Yinian Yang Wenqiang Xu Jinmei Sun Lu Wang Anzhen Wang Gong-Jun Ji Kai Wang Source Type: research

Correction to: "Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness"
J Psychiatry Neurosci. 2023 Dec 20;48(6):E471. doi: 10.1503/jpn.230160. Print 2023 Nov-Dec.NO ABSTRACTPMID:38123243 | PMC:PMC10743624 | DOI:10.1503/jpn.230160 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - December 20, 2023 Category: Psychiatry Source Type: research