Ending the overdose epidemic by ending the war on drug users: Can this work?
J Psychiatry Neurosci. 2024 Feb 21;49(1):E77-E80. doi: 10.1503/jpn.240003. Print 2024 Jan-Feb.NO ABSTRACTPMID:38383036 | DOI:10.1503/jpn.240003 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 21, 2024 Category: Psychiatry Authors: Marco Leyton R Michael Krausz Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia
CONCLUSION: Epigenetic modifications of the immune system are associated with symptom severity at onset and subsequent treatment response in schizophrenia.PMID:38359932 | DOI:10.1503/jpn.230099 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Yuanhao Tang Yunlong Tan Lena Palaniyappan Yin Yao Qiang Luo Yanli Li Source Type: research

Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review
CONCLUSION: Pharmacologically enhanced TMS largely parallels findings from ex vivo preparations. As this area expands and novel targets are tested, adequately powered samples in healthy and clinical populations will inform the mechanisms of TMS-induced plasticity in health and disease.PMID:38359933 | DOI:10.1503/jpn.230090 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 15, 2024 Category: Psychiatry Authors: Myren N Sohn Joshua C Brown Prayushi Sharma Ulf Ziemann Alexander McGirr Source Type: research

Reviving: restoring depression-like behaviour through glial cell-derived neurotrophic factor treatment in the medial prefrontal cortex
CONCLUSION: Our findings support a positive effect of exogenous GDNF on synaptic plasticity, mediated by DRD1 signalling in the mPFC, which could facilitate depression remission in Parkinson disease.PMID:38302136 | PMC:PMC10843345 | DOI:10.1503/jpn.230079 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 1, 2024 Category: Psychiatry Authors: Yehao Liu Xiaoyu Zhou Ke Xue Ruiao Sun Yan Tang Chuanxi Tang Source Type: research

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia
CONCLUSION: We found global HPTM alterations consistent with an aberrantly permissive epigenome in schizophrenia. Further studies to elucidate the significance of enhanced permissive HPTMs in schizophrenia and its association with the mechanism of action of antipsychotic drugs are encouraged.PMID:38302137 | PMC:PMC10843339 | DOI:10.1503/jpn.230054 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - February 1, 2024 Category: Psychiatry Authors: Oihane Mart ínez-Peula Benito Morentin Luis F Callado J Javier Meana Guadalupe Rivero Alfredo Ramos-Miguel Source Type: research