DSM-5 Pocket Guide for Elder Mental Health
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Book Review Source Type: research

Does Involuntary Admission With Bipolar Disorder Differ From Involuntary Admission With Schizophrenia and Related Disorders? A Report From the Dublin Involuntary Admission Study (DIAS)
Background: While involuntary psychiatric admission and treatment are common, little is known about what impact different diagnoses have on specific features of involuntary admission and on how involuntary status is terminated (eg, by psychiatrists or tribunals, which are independent, court-like bodies reviewing involuntary admissions). Methods: We studied 2940 admissions, 423 (14.4%) of which were involuntary, at 3 psychiatry units covering a population of 552,019 individuals in Dublin, Ireland. Results: Involuntary patients were more likely than voluntary patients to be male and unmarried. The median length of st...
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Practitioner’S Corner Source Type: research

Brain and Behavior: Commentary on Two Cases Involving the Effect of Structural Brain Lesions on Psychiatric Disorders
In this issue of the journal, 2 case reports are presented that illustrate explicit influences of structural brain lesions on psychiatric symptoms. In both cases, the patients had preexisting, classically diagnosed psychiatric disorders—schizophrenia in the first case and bipolar I disorder in the second case. In the first case, a 61-year-old woman with chronic paranoid schizophrenia experienced a marked reduction in psychotic symptoms after bilateral frontal strokes. In the second case, a 60-year-old man who had experienced manic and depressive episodes since his 20s developed partial complex seizures after having r...
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Differentiating Symptoms of Bipolar Disorder From Those of Temporal Lobe Epilepsy: A Case Report
We describe an individual with a history of bipolar I disorder who developed right temporal lobe epilepsy after several head injuries. He subsequently exhibited symptoms consistent with interictal personality syndrome that were independent of his bipolar symptomatology. Better understanding of these disorders can lead to improved diagnosis and symptom management. The similarities may also point to a partially shared neuropathology. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Poststroke Psychosis Reduction: A Case Report
In this report, we review poststroke psychiatric manifestations, and then present the case of a woman with schizophrenia whose thought disorder improved following a hemorrhagic stroke. Not only did she require less medication, but her remaining symptoms were significantly less impairing than they had previously been. We then compare and contrast the effects of this stroke with ablative neurosurgery. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Clinical Necessity Guidelines for Psychotherapy, Insurance Medical Necessity and Utilization Review Protocols, and Mental Health Parity
The founding members of the Coalition for Psychotherapy Parity present Clinical Necessity Guidelines for Psychotherapy, Insurance Medical Necessity and Utilization Review Protocols, and Mental Health Parity. These guidelines support access to psychotherapy as prescribed by the clinician without arbitrary limitations on duration or frequency. The authors of the guidelines first review the evidence that psychotherapy is effective, cost-effective, and often provides a cost-offset in decreased overall medical expenses, morbidity, mortality, and disability. They highlight the disparity between clinicians’ knowledge of gen...
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Column Source Type: research

Predictors of Lifetime Suicide Attempts in Individuals With Attenuated Psychosis Syndrome
Conclusions: Suicidality is a prominent feature of APS, and a number of risk factors increase the likelihood of suicide attempts in this population. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Perinatal Mental Health Treatment Needs, Preferences, and Barriers in Parents of Multiples
Conclusions: There is a large, unmet need for mental health treatment in parents of multiples in the perinatal period, especially the early postpartum months. eHealth strategies seem particularly feasible and acceptable in this population and may help circumvent common barriers to care. Clinical recommendations and considerations in treatment development are discussed. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Symptom Dimensions and Trajectories of Functioning Among Bipolar Youth: A Cluster Analysis
This study used a full diagnostic instrument to examine symptom patterns among youth with BD. Method: Trained interviewers completed the Washington University Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) with 71 children (7 to 13 y of age) and families as part of the baseline assessment for a randomized clinical trial of Child- and Family-focused Cognitive-Behavioral Therapy (CFF-CBT) compared with treatment as usual (TAU) for pediatric BD. All participants met DSM-IV-TR criteria for a bipolar spectrum disorder. Hierarchical and K-means cluster analyses were performed. Resultant cluste...
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Characteristics of Successful Transitions From Inpatient to Outpatient Electroconvulsive Therapy
Objectives: The purpose of this study was to identify clinical and psychosocial factors involved in transitioning hospitalized patients receiving electroconvulsive therapy (ECT) from the inpatient to the outpatient setting and to propose an algorithm to guide clinicians with this process. Methods: A retrospective chart review was completed for adult patients discharged from a psychiatric hospital from 2002 to 2012 who had an acute course of ECT that was initiated in the hospital and completed as an outpatient. We reviewed demographic and clinical information and outcomes, including ECT treatments. Results: Among th...
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Multiples
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - May 1, 2018 Category: Psychiatry Tags: From the Editor Source Type: research

Bipolar, Not So Much: Understanding Your Mood Swings and Depression
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Book Review Source Type: research

Beyond Social Media: A Cross-Sectional Survey of Other Internet and Mobile Phone Applications in a Community Psychiatry Population
Conclusions: Our findings indicate that use of several popular forms of media is not uncommon in a community psychiatry population, but that rates of use differ on the basis of age and education. As the digital divide between people with severe mental illness and the general population is lessening, further research is needed to determine how to best leverage various types of media to support mental health recovery and complement clinical care. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Practitioner's Corner Source Type: research

Commentary on 2 Cases of Rare but Serious Side Effects of Commonly Used Medications: Dilemmas in Clinical Decision-making
In this issue of the journal, 2 case reports are presented that describe rare but serious side effects of commonly used medications. These cases illustrate dilemmas in clinical decision-making. The first describes the induction of seizures by low-dose venlafaxine in a predisposed individual, and the second describes the development of mild but significant leukopenia with sequential trials of olanzapine and risperidone. The association between a drug and a rare but potentially serious side effect in an individual patient can be difficult to determine with precision, and the decision to press ahead and try to work around the...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Olanzapine-induced and Risperidone-induced Leukopenia: A Case of Synergistic Adverse Reaction?
We report a case of an antipsychotic-naive patient with schizophrenia who developed leukopenia after a single dose of olanzapine, which worsened during subsequent treatment with risperidone. Normalization of the white blood cell counts occurred within 24 hours of risperidone discontinuation. Possible synergistic mechanisms underlying olanzapine-induced and risperidone-induced leukopenia are discussed. This case highlights the challenges in identifying and managing nonclozapine antipsychotic-induced leukopenia in a susceptible patient. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Seizure Induced by a Therapeutic Dose of Venlafaxine ER: A Case Report
We report the case of a 44-year-old woman undergoing antituberculosis therapy who suffered complex partial seizures after ingestion of a low therapeutic dose of venlafaxine extended release (ER). Her first seizure was observed soon after venlafaxine ER was titrated from 37.5 to 75 mg daily, with a total of 9 witnessed complex partial seizures. After titrating the dose of the venlafaxine ER back down to 37.5 mg daily and beginning lamotrigine anticonvulsant therapy, the patient exhibited no further seizures. The development of seizure activity under therapeutic dosing of venlafaxine should be brought to the at...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Clinical and Insurance Perspectives on Intermediate Levels of Care in Psychiatry
This column compares a clinical perspective on the continuum of care for mental health and substance use disorders with a different perspective derived from publicly available insurance company documents and experience dealing with managed care utilization reviewers. The latter perspective tends to determine the need for access to levels of care based on the need for crisis stabilization, whereas the generally accepted clinical standard is more nuanced than the need for crisis stabilization alone. The column proposes that this discrepancy in perspectives makes a substantial contribution to disagreements between treating cl...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

CNS Drug Development, Lessons Learned, Part 5: How Preclinical and Human Safety Studies Inform the Approval and Subsequent Use of a New Drug—Suvorexant as an Example
This column is the fifth in a series examining the advances being made in central nervous system drug development because of advances in molecular pharmacology and an improved understanding of the neurobiology underlying disturbances in brain function including psychiatric illnesses. This column covers the special animal and human studies conducted as part of the development of suvorexant, which is the first in the class of dual orexin 1 and 2 receptor antagonists to be approved; it has an indication for the treatment of disturbances in sleep onset and maintenance. The animal studies included determination of the therapeut...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

Does Late-onset Anorexia Nervosa Exist? Findings From a Comparative Study in Singapore
Conclusions: Although differences exist between early-onset and late-onset cases of AN, these are few. Until stronger evidence emerges over time, there currently seems to be minimal justification to accord late-onset AN a unique position in psychiatric nosology. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

What Therapies are Favored in the Treatment of the Psychological Sequelae of Trauma in Human Trafficking Victims?
Human trafficking is a major public health concern that brings about deleterious psychological consequences and sequelae. Although a number of risk and protective factors for the health consequences of human trafficking victims have been identified, there is a dearth of information in the area of treatment. Specifically, we found no articles comparing the different components of prevailing trauma treatment strategies, and the potential usefulness of these strategies in the treatment of human trafficking victims. To this end, we compared and contrasted the different therapeutic treatments typically implemented with victims ...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Psychiatry’s Role in the Management of Human Trafficking Victims: An Integrated Care Approach
Human trafficking is an outrageous human rights violation with potentially devastating consequences to individuals and the public health. Victims are often underrecognized and there are few guidelines for how best to identify, care for, and safely reintegrate victims back into the community. The purpose of this paper is to propose a multifaceted, interdisciplinary, and interprofessional guideline for providing care and services to human trafficking victims. Databases such as PubMed and PsycINFO were searched for papers outlining human trafficking programs with a primary psychiatric focus. No integrated care models that pro...
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Relationship Between Antipsychotic Medications and Cerebrovascular Disease in Patients With Serious Mental Illness
Conclusions: In this study, in contrast to previous reports, use of antipsychotic medications and the presence of SMI were not associated with an increased risk of CVD. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Human Trafficking
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - March 1, 2018 Category: Psychiatry Tags: From the Editor Source Type: research

Clinical Manual of Child and Adolescent Psychopharmacology, Third Edition
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Book Review Source Type: research

Examining the Feasibility and Acceptability of an Online Yoga Class for Mood Disorders: A MoodNetwork Study
Discussion: These preliminary data support the utility of online yoga tailored specifically for people with mood disorders as a possible adjunctive intervention that warrants further investigation. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Practitioner's Corner Source Type: research

Ketamine Use for Suicidal Ideation in the General Hospital: Case Report and Short Review
We report on the use of ketamine as an efficient, well-tolerated treatment for persistent suicidal ideation in a patient hospitalized in a general hospital after a severe suicide attempt. Based on data in the literature, we suggest that the benefit-risk ratio for ketamine use in such a context is highly favorable. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Cannabinoid Hyperemesis Syndrome and the Consulting Psychiatrist: A Case Study of Diagnosis and Treatment for an Emerging Disorder in Psychiatric Practice
We present a case of cannabinoid hyperemesis syndrome that required psychiatric consultation for diagnostic clarification and effective treatment with intravenous haloperidol. Literature from emergency medicine, toxicology, and gastroenterology is reviewed, including proposed diagnostic criteria for cannabinoid hyperemesis syndrome and reported off-label treatment options, with a specific focus on clinical questions facing the practicing psychiatrist regarding this emerging disorder. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

The Mask of Happiness: Unmasking Coercive Control in Intimate Relationships
This article defines and exemplifies the dynamic of coercive control, a more insidious and difficult to identify process of domination and exploitation that victims have a hard time labeling on their own. Further reading and resources are also provided. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

Two New Psychotherapy Studies: Back to the Future?
This column reviews 2 recent high-quality psychotherapy research studies. One study by Steinert and colleagues suggests that psychodynamic therapy is equivalent to cognitive behavioral therapy (CBT) (or medication when this was the comparator) for a range of disorders. A second study by Barlow and colleagues finds Unified Protocol CBT targeting underlying emotional dysregulation to be equivalent to single disorder-specific CBT for a range of anxiety disorders. Taken together, these studies help bridge the gap between CBT and psychodynamic therapy and refocus us on the realities of clinical settings, where most patients pre...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

A Brief Interview to Detect Panic Attacks and Panic Disorder in Emergency Department Patients with Cardiopulmonary Complaints
Conclusions: Patients with panic attacks or panic disorder commonly present to the ED, but often go unrecognized. A brief 7-item clinician rating scale accurately identifies these patients among those ED patients presenting with cardiopulmonary complaints. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Reducing the Risk of Type 2 Diabetes in Nonselected Outpatients With Schizophrenia: A 30-Month Program
Conclusion: The study found that positive outcomes were associated with female sex and a longer duration of illness. Negative outcomes with worsening of risk factors were associated with being newly diagnosed with schizophrenia and male sex. It was possible to produce improvements in some risk factors through individual health-oriented lifestyle interventions, especially in LT patients. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Botulinum Toxin as a Treatment for Depression in a Real-world Setting
Objectives: A series of randomized controlled trials have shown the efficacy of glabellar botulinum toxin (BTX) injection as a treatment for depression in women. We wanted to extend these findings and assess how they may be translated to a real-world setting. Methods: For that purpose, 42 patients with severe, in most cases chronic and treatment-resistant depression received adjunctive treatment with BTX in private practice. Depression severity was rated before and 3 weeks after the treatment using the Hamilton Depression Rating Scale, the Montgomery Åsberg Depression Rating Scale, and the Beck Depression Invent...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

An Examination of Fluoxetine for the Treatment of Selective Mutism Using a Nonconcurrent Multiple-Baseline Single-Case Design Across 5 Cases
This study examined the utility of fluoxetine in the treatment of 5 children, aged 5 to 14 years, diagnosed with selective mutism who also demonstrated symptoms of social anxiety. A nonconcurrent, randomized, multiple-baseline, single-case design with a single-blind placebo-controlled procedure was used. Parents and the study psychiatrist completed multiple methods of assessment including Direct Behavior Ratings and questionnaires. Treatment outcomes were evaluated by calculating effect sizes for each participant as an individual and for the participants as a group. Information regarding adverse effects with an emphasis on...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Out of the Box
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: From the Editor Source Type: research

Clinical Manual of Child and Adolescent Psychopharmacology, Third Edition
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Book Review Source Type: research

Examining the Feasibility and Acceptability of an Online Yoga Class for Mood Disorders: A MoodNetwork Study
Discussion: These preliminary data support the utility of online yoga tailored specifically for people with mood disorders as a possible adjunctive intervention that warrants further investigation. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Practitioner's Corner Source Type: research

Ketamine Use for Suicidal Ideation in the General Hospital: Case Report and Short Review
We report on the use of ketamine as an efficient, well-tolerated treatment for persistent suicidal ideation in a patient hospitalized in a general hospital after a severe suicide attempt. Based on data in the literature, we suggest that the benefit-risk ratio for ketamine use in such a context is highly favorable. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Cannabinoid Hyperemesis Syndrome and the Consulting Psychiatrist: A Case Study of Diagnosis and Treatment for an Emerging Disorder in Psychiatric Practice
We present a case of cannabinoid hyperemesis syndrome that required psychiatric consultation for diagnostic clarification and effective treatment with intravenous haloperidol. Literature from emergency medicine, toxicology, and gastroenterology is reviewed, including proposed diagnostic criteria for cannabinoid hyperemesis syndrome and reported off-label treatment options, with a specific focus on clinical questions facing the practicing psychiatrist regarding this emerging disorder. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

The Mask of Happiness: Unmasking Coercive Control in Intimate Relationships
This article defines and exemplifies the dynamic of coercive control, a more insidious and difficult to identify process of domination and exploitation that victims have a hard time labeling on their own. Further reading and resources are also provided. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

Two New Psychotherapy Studies: Back to the Future?
This column reviews 2 recent high-quality psychotherapy research studies. One study by Steinert and colleagues suggests that psychodynamic therapy is equivalent to cognitive behavioral therapy (CBT) (or medication when this was the comparator) for a range of disorders. A second study by Barlow and colleagues finds Unified Protocol CBT targeting underlying emotional dysregulation to be equivalent to single disorder-specific CBT for a range of anxiety disorders. Taken together, these studies help bridge the gap between CBT and psychodynamic therapy and refocus us on the realities of clinical settings, where most patients pre...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Columns Source Type: research

A Brief Interview to Detect Panic Attacks and Panic Disorder in Emergency Department Patients with Cardiopulmonary Complaints
Conclusions: Patients with panic attacks or panic disorder commonly present to the ED, but often go unrecognized. A brief 7-item clinician rating scale accurately identifies these patients among those ED patients presenting with cardiopulmonary complaints. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Reducing the Risk of Type 2 Diabetes in Nonselected Outpatients With Schizophrenia: A 30-Month Program
Conclusion: The study found that positive outcomes were associated with female sex and a longer duration of illness. Negative outcomes with worsening of risk factors were associated with being newly diagnosed with schizophrenia and male sex. It was possible to produce improvements in some risk factors through individual health-oriented lifestyle interventions, especially in LT patients. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Botulinum Toxin as a Treatment for Depression in a Real-world Setting
Objectives: A series of randomized controlled trials have shown the efficacy of glabellar botulinum toxin (BTX) injection as a treatment for depression in women. We wanted to extend these findings and assess how they may be translated to a real-world setting. Methods: For that purpose, 42 patients with severe, in most cases chronic and treatment-resistant depression received adjunctive treatment with BTX in private practice. Depression severity was rated before and 3 weeks after the treatment using the Hamilton Depression Rating Scale, the Montgomery Åsberg Depression Rating Scale, and the Beck Depression Invent...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

An Examination of Fluoxetine for the Treatment of Selective Mutism Using a Nonconcurrent Multiple-Baseline Single-Case Design Across 5 Cases
This study examined the utility of fluoxetine in the treatment of 5 children, aged 5 to 14 years, diagnosed with selective mutism who also demonstrated symptoms of social anxiety. A nonconcurrent, randomized, multiple-baseline, single-case design with a single-blind placebo-controlled procedure was used. Parents and the study psychiatrist completed multiple methods of assessment including Direct Behavior Ratings and questionnaires. Treatment outcomes were evaluated by calculating effect sizes for each participant as an individual and for the participants as a group. Information regarding adverse effects with an emphasis on...
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: Articles Source Type: research

Out of the Box
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - January 1, 2018 Category: Psychiatry Tags: From the Editor Source Type: research

Becoming Mindful: Integrating Mindfulness Into Your Psychiatric Practice
No abstract available (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - November 1, 2017 Category: Psychiatry Tags: Book Review Source Type: research

Reward Dysfunction in the Manic Spectrum: Unable to Win? The Use of Biographical Information to Refine Neurobiological Modeling
Conclusions: The experience and neural correlates of hedonic processing may be impaired in the manic spectrum. Possible mechanisms for this impairment and its dissociation from the earlier stage of reward processing characterized by hyperactive reward pursuit are considered. Clinical reports and longitudinal, life-based follow-up can provide important data to supplement more experimentally based neurobiological models of reward dysfunction in bipolar disorders. (Source: Journal of Psychiatric Practice)
Source: Journal of Psychiatric Practice - November 1, 2017 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research

Voltage-gated Potassium Channel Antibody Autoimmune Encephalopathy Presenting With Isolated Psychosis in an Adolescent
Antibody-mediated encephalopathies associated with serum or cerebrospinal fluid antibodies directed against neuronal structures may present with a multitude of neuropsychiatric syndromes. Although some of the antibody-driven conditions are now well recognized in adults (eg, N-methyl-D-aspartate receptor antibody encephalitis), the spectrum of neuropsychiatric manifestations in the pediatric population is less clear. Psychosis, confusion, catatonia, and additional behavioral changes, along with seizures, encephalopathy, and movement disorders, may be initial manifestations or concurrent features in all age groups. Psychosis...
Source: Journal of Psychiatric Practice - November 1, 2017 Category: Psychiatry Tags: Clinical Case Discussions Source Type: research