Transient congenital hypothyroidism & #8211; too short to be transient
K SubramaniamJournal of Postgraduate Medicine 2021 67(4):238-240
Congenital hypothyroidism (CH) occurs due to thyroid dysgenesis, thyroid ectopy, and dyshormonogenesis. A proportion of CH is transient which might be due to iodine deficiency/excess or maternal antibody-mediated. Certain forms of dyshormonogenetic defects may cause transient hypothyroidism. Here is a report of a neonate with overt clinical and biochemical hypothyroidism, who on evaluation was found to have dyshormonogenesis with a homozygous mutation in dual oxidase 2 (DUOX2) gene. During infancy, she became euthyroid. Severe in utero deficiency of thyroid ...
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: K Subramaniam Source Type: research
Recurrent aplastic anemia with donor-type aplasia: A rare occurrence in the Indian subcontinent
A Majumder, S Misra, V KumarJournal of Postgraduate Medicine 2021 67(4):235-237
Donor-type aplasia (DTA) is a condition where an individual continues to be aplastic even after a successful engraftment of a hematopoeitic stem cell transplant with a majority of donor type cells in the bone marrow. This entity has been seen with varying frequency around the world, especially in Southeast Asia. However, its incidence in the Indian subcontinent remains fairly low. Here is a case of a 17-year-old child with DTA who had a 89% population of donor cells after a successful transplant and presented with recurrent severe a...
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: A Majumder S Misra V Kumar Source Type: research
A rare case of duodenal inversum- A laparoscopically manageable entity
P Dasgupta, S Somasundaram, S Balasubramanian, S PalanisamyJournal of Postgraduate Medicine 2021 67(4):232-234
Duodenal inversum is a rare disease not frequently encountered in clinical practice. The diagnosis is usually made late due to its rarity. Many other causes of abdominal pain like ulcer disease, pancreatitis, malrotation are mostly thought of initially and the diagnosis is usually missed. Only a few cases of duodenal inversum present with outlet obstruction. Duodenojejunostomy is perhaps the ideal management for duodenal inversum if the patient presents with outlet obstruction. Our intention is to create awarenes...
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: P Dasgupta S Somasundaram S Balasubramanian S Palanisamy Source Type: research
Bilateral idiopathic temporal bone meningoencephaloceles - An unusual presentation
We report a case of bilateral idiopathic temporal bone MECs with a rare presentation of autophony as the chief complaint. The differentiating features on computed tomography scan and magnetic resonance imaging and the surgical management are discussed. (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: SN Muranjan DD Singhal SH Shah AK Shah Source Type: research
Sequelae of COVID-19 pneumonia: Is it correct to label everything as post-COVID lung fibrosis ?
M Garg, M Maralakunte, S DhooriaJournal of Postgraduate Medicine 2021 67(4):224-227
One of the common long-term consequences observed in survivors of COVID-19 pneumonia is the persistence of respiratory symptoms and/or radiological lung abnormalities. The exact prevalence of these post-COVID pulmonary changes is yet unclear. Few authors, based on their early observations, have labeled these persistent computed tomography (CT) abnormalities as post-COVID lung fibrosis, which appears to be an overstatement. Lately, it is being observed that many of the changes seen in post-COVID lungs are temporary and tend to show resoluti...
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: M Garg M Maralakunte S Dhooria Source Type: research
The importance of small samples in medical research
A Indrayan, A MishraJournal of Postgraduate Medicine 2021 67(4):219-223
Almost all bio-statisticians and medical researchers believe that a large sample is always helpful in providing more reliable results. Whereas this is true for some specific cases, a large sample may not be helpful in more situations than we contemplate because of the higher possibility of errors and reduced validity. Many medical breakthroughs have occurred with self-experimentation and single experiments. Studies, particularly analytical studies, may provide more truthful results with a small sample because intensive efforts can be made to control a...
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: A Indrayan A Mishra Source Type: research
Factors determining outcome of post-angiogram-negative subarachnoid hemorrhage
Conclusions: At time of admission, presence of hypertension, diabetes mellitus, history of alcohol consumption, and poor grades of HHS and WFNS scale are predictors of poor outcome of angio-negative SAH. (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: N Kumar S Gupta Source Type: research
Effect of mobile voice calls on treatment initiation among patients diagnosed with tuberculosis in a tertiary care hospital of Puducherry: A randomized controlled trial
Conclusion: Mobile voice call reminder to patients is a feasible intervention and can reduce PTLFU among referred TB patients. (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: MG Majella P Thekkur AM Kumar P Chinnakali VK Saka G Roy Source Type: research
Impact of the COVID-19 pandemic on the management of surgical patients presenting in an emergency setting -Report from a tertiary referral centre
Conclusions: The number of COVID-19 positive patients rose serially over the study period. The outcome was not affected by the COVID-19 status in mild cases. A high rate of COVID-19 positivity was seen in patients requiring emergency surgery. Universal precautions ensured delivering treatment to emergency patients in standard time. Testing should continue for all as screening alone is not effective as the virus spreads into the population. Proper protocols helped us to protect the health care workers. (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: AA Deshpande AA Das SB Deotale YP Takalkar Source Type: research
Donor-type aplasia after stem cell transplantation in aplastic anaemia: Current understanding and intervention
K GhoshJournal of Postgraduate Medicine 2021 67(4):196-197 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: K Ghosh Source Type: research
Leveraging mHealth intervention to ensure initiation of treatment for tuberculosis
VR KeshriJournal of Postgraduate Medicine 2021 67(4):194-195 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: VR Keshri Source Type: research
Published a research paper ? What next ? ?
CA Divecha, MS Tullu, S KarandeJournal of Postgraduate Medicine 2021 67(4):189-193 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - November 26, 2021 Category: Internal Medicine Authors: CA Divecha MS Tullu S Karande Source Type: research
Spontaneous breast hematoma following thrombolytic therapy
N Moorthy, JH Venkatappa, A Palakshachar, R RamalingamJournal of Postgraduate Medicine 2021 67(3):188-188 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - August 20, 2021 Category: Internal Medicine Authors: N Moorthy JH Venkatappa A Palakshachar R Ramalingam Source Type: research
Post-traumatic hepatic artery pseudoaneurysm with recurrent hemoperitoneum and repeated laparotomies treated by endovascular coil embolization
S Mohakud, PK Sasmal, D Das, P KumarJournal of Postgraduate Medicine 2021 67(3):186-187 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - August 20, 2021 Category: Internal Medicine Authors: S Mohakud PK Sasmal D Das P Kumar Source Type: research
Isolated aquagenic acrokeratoderma of dorsal hands
P Pande, K Poonia, J KaurJournal of Postgraduate Medicine 2021 67(3):184-185 (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - August 20, 2021 Category: Internal Medicine Authors: P Pande K Poonia J Kaur Source Type: research
