Journal of Pharmacy and Pharmacology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Nanomedicine: a new paradigm to overcome drug incompatibilities
ConclusionsThere is a new era of exploiting nanomaterials in overcoming various types of physicochemical incompatibilities, with additional benefits of further improvements in pharmacokinetic profiles and pharmacological actions of the administered drugs. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 20, 2020 Category: Drugs & Pharmacology Authors: Ayat Abdelkader, Heba A. Fathi, Mostafa A. Hamad, Mahmoud Elsabahy Tags: Review Source Type: research

Curcumin alleviates OGD/R ‐induced PC12 cell damage via repressing CCL3 and inactivating TLR4/MyD88/MAPK/NF‐κB to suppress inflammation and apoptosis
ConclusionsOur study manifested that curcumin might be a meritorious drug for the treatment of cerebral ischaemia by acting on CCL3. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 20, 2020 Category: Drugs & Pharmacology Authors: Chao Wang, Yong ‐Hong Yang, Liang Zhou, Xin‐Li Ding, Ying‐Chun Meng, Ke Han Tags: Research Paper Source Type: research

The inhibitory effects of shikonin and β,β‐dimethylacrylshikonin on tramadol metabolism in vitro and in vivo
ConclusionsThe results of this study suggest that shikonin and DSK can inhibit tramadol metabolism bothin vitro andin vivo. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 18, 2020 Category: Drugs & Pharmacology Authors: Mi Jin, Dawei Shi, Hui Jin, Ziye Zhou, Chenxiang Wang Tags: Research Paper Source Type: research

A çaí berries (Euterpe oleracea Mart.) dried extract improves ethanol‐induced ulcer in rats
ConclusionsOur findings suggest that DAE reduces the inflammation and maintains the oxidative balance of gastric mucosa, therefore being a promising natural resource or useful nutraceutical to protect gastric mucosa. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 18, 2020 Category: Drugs & Pharmacology Authors: Benhur Judah Cury, Thaise Boeing, Lincon Bordignon Somensi, Luisa Nath ália Bolda Mariano, Sergio Faloni Andrade, Eduardo Breviglieri, Luiz Carlos Klein‐Junior, Priscila Souza, Luisa Mota Silva Tags: Research Paper Source Type: research

Serum metabolomics reveals the intervention mechanism and compatible regularity of Chaihu Shu Gan San on chronic unpredictable mild stress ‐induced depression rat model
ConclusionsCSGS produced an obvious antidepressant activity. The comprehensive and holistic metabolomics approach could be a powerful tool to study the intervention mechanism and the compatibility rule of traditional Chinese medicine. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 16, 2020 Category: Drugs & Pharmacology Authors: Hongye Zhang, Huimin Huang, Hui Song, Bonnie Chin, Hua Zheng, Junxiang Ruan, Fang Wu, Bang Cheng, Jinxia Wu, Xuwen Liu, Yonghong Liang, Fangming Song, Zhaoni Chen, Chaoling Tang, Shiyin Lu, Hongwei Guo, Zhongmei Zou, Zhiheng Su Tags: Research Paper Source Type: research

14,15 β‐dihydroxyklaineanone inhibits HepG2 cell proliferation and migration through p38MAPK pathway
Conclusions14,15 β‐dihydroxyklaineanone inhibited cell proliferation and migration through regulating p38 MAPK pathway in HCC cells. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 16, 2020 Category: Drugs & Pharmacology Authors: Xiao ‐Dong Pei, Song‐Qing He, Li‐Qun Shen, Jing‐Chen Wei, Xue‐Sheng Li, Yan‐Yan Wei, Yu‐Meng Zhang, Xin‐Yu Wang, Feng Lin, Zhi‐Long He, Li‐He Jiang Tags: Research Paper Source Type: research

Astragaloside IV ameliorates radiation ‐induced senescence via antioxidative mechanism
ConclusionsThese data suggest that AS ‐IV can antagonize radiation‐induced brain cells senescence; and its mechanism may be related to p53‐p21 and p16‐RB signalling pathways of ageing regulation. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 14, 2020 Category: Drugs & Pharmacology Authors: Xin Liu, Shuying Shang, Weiwei Chu, Liang Ma, Chenxin Jiang, Yanping Ding, Jianlin Wang, Shengxiang Zhang, Baoping Shao Tags: Research Paper Source Type: research

Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR ‐143‐3p/TGF‐β1 axis
ConclusionsOur studies demonstrated that the protective effect of MET on DN was attributed to the inhibition of proliferation, inflammation and ECM accumulation in mesangial cells via H19/miR ‐143‐3p/TGF‐β1 axis, which suggested that the H19/miR‐143‐3p/TGF‐β1 axis could be a valuable target for DN therapies. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 10, 2020 Category: Drugs & Pharmacology Authors: Jiang Xu, Ping Xiang, Linqing Liu, Jianran Sun, Shandong Ye Tags: Research Paper Source Type: research