Different voltage dependence of ICaL blockade in nonselective IKr blockers causes their opposite effects on early afterdepolarization in drug-induced arrhythmia
Publication date: Available online 5 June 2021Source: Journal of Pharmacological SciencesAuthor(s): Akira Kimura, Shingo Murakami (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - June 6, 2021 Category: Drugs & Pharmacology Source Type: research

Diverse intracellular signaling pathways mediate the effects of neurotensin on the excitability of type II neurons in the rat dorsolateral bed nucleus of the stria terminalis
Publication date: Available online 5 June 2021Source: Journal of Pharmacological SciencesAuthor(s): Tomoyuki Kaneko, Ryuto Hara, Taiju Amano, Masabumi Minami (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - June 6, 2021 Category: Drugs & Pharmacology Source Type: research

Local administration of ReveromycinA ointment suppressed alveolar bone loss in mice
Publication date: Available online 27 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Ken Miyazawa, Yuichiro Asano, Masako Tabuchi, Shunsuke Kako, Makoto Kawatani, Hiroyuki Osada, Hatsuhiko Maeda, Shigemi Goto (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 28, 2021 Category: Drugs & Pharmacology Source Type: research

Nicotine enhances object recognition memory through inhibition of voltage-dependent potassium 7 channels in the medial prefrontal cortex of mice
Publication date: Available online 24 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Hirohito Esaki, Shoma Izumi, Akari Fukao, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaneda (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 25, 2021 Category: Drugs & Pharmacology Source Type: research

Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2
Publication date: Available online 23 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Titilayo O. Johnson, Abayomi Emmanuel Adegboyega, Opeyemi Iwaloye, Omokehinde Abiodun Eseola, Winfried Plass, Boluwatife Afolabi, Damilare Rotimi, Eman I. Ahmed, Ashraf Albrakati, Gaber E. Batiha, Oluyomi Stephen Adeyemi (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia
Publication date: Available online 23 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Megumi Kikuya, Kenta Furuichi, Takuya Hirao, Satoshi Endo, Naoki Toyooka, Kousei Ito, Shigeki Aoki (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Vascular sympathetic neurotransmission and its serotonergic regulation are modified by chronic fluoxetine treatment
Publication date: Available online 23 May 2021Source: Journal of Pharmacological SciencesAuthor(s): José Ángel García-Pedraza, Cristina López, Juan Francisco Fernández-González, María Luisa Martín, Asunción Morán, Mónica García-Domingo (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Calunduloside E inhibits HepG2 cell proliferation and migration via p38/JNK-HMGB1 signalling axis
Publication date: Available online 24 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Shengnan Wang, Xuelei Chen, Jin Cheng, Tianyu Cai, Xiaoming Wu, Zhenyu Cheng, Shimei Qi, Zhilin Qi (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways
Publication date: Available online 24 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Ziheng Wei, Yurun Xue, Yucong Xue, Jie Cheng, Guoping Lv, Li Chu, Zhihong Ma, Shengjiang Guan (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Andrographolide improves PCP-induced schizophrenia-like behaviors through blocking interaction between NRF2 and KEAP1
Publication date: Available online 24 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Xiying Wang, Jia Liu, Zhiping Dai, Yuxiu Sui (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Resolvins as potential candidates for the treatment of major depressive disorder
Publication date: Available online 24 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Satoshi Deyama, Masabumi Minami, Katsuyuki Kaneda (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 24, 2021 Category: Drugs & Pharmacology Source Type: research

Linalyl acetate as a potential preventive agent against muscle wasting in rheumatoid arthritis rats chronically exposed to nicotine
Publication date: Available online 21 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Eunhye Seo, You Kyoung Shin, Yu Shan Hsieh, Jeong-Min Lee, Geun Hee Seol (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 22, 2021 Category: Drugs & Pharmacology Source Type: research

Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway
Publication date: Available online 11 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Fang Xianjun, Xian Xirui, Tang Jie, Mu Huiwen, Zheng Shaojun, Ling Qiaoyun, Liu Yunxin, Sun Xuqun (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 11, 2021 Category: Drugs & Pharmacology Source Type: research

Lymphangiogenesis and angiogenesis rescue murine ischemic hindlimb via transient receptor potential vanilloid 4
Publication date: Available online 11 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Hideaki Yamada, Naoaki Sakata, Tomoko Tanaka, Hideaki Tagashira, Gumpei Yoshimatsu, Ryo Kawakami, Hideichi Wada, Takahiro Iwamoto, Shohta Kodama (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 11, 2021 Category: Drugs & Pharmacology Source Type: research

Emodin-induced autophagic cell death hinders epithelial–mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis
Publication date: Available online 1 May 2021Source: Journal of Pharmacological SciencesAuthor(s): Wei Liu, Renyi Gu, Yujiao Lou, Chunfeng He, Qingchuan Zhang, Dongmei Li (Source: Journal of Pharmacological Sciences)
Source: Journal of Pharmacological Sciences - May 7, 2021 Category: Drugs & Pharmacology Source Type: research