Effects of amphetamine and morphine on respiration, body temperature, and locomotor activity relative to time of administration in rats
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Jonelle R. May, Kyle P. O'Donohue, Anson L. Phillips, Jill A. Dalton, Theodore J. Baird (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Comparison of impact of administration route (oral gavage and continuous infusion) on whole body plethysmography results using a respiratory stimulant in conscious rats
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Allister Williams, Marcus Chamberlain, Jill Nichols, Angela Batman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Changes in the housing arrangement (single versus paired) in cynomolgus monkeys and the impact on telemetry data in drug safety evaluations
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): David L. Holdsworth, Kyle P. O'Donohue, Jordan T. Van Hall, Jill A. Dalton, Theodore J. Baird (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Non-invasive chronic glucose sampling in a diabetic porcine model: Refinement and utility of continuous blood glucose monitors
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Rebecca Ober, Beth Geist (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Use of vascular access buttons (VABs) in rodent telemetry safety studies
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Matt Skinner, Alan McCarthy (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Impact of enforced and normal social housing on stress level and cardiovascular response in rat telemetry study
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Vijay Urmaliya, Hanne Daems, Fetene Tekle, Ard Teisman, David J. Gallacher (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Drug schedule control status does not limit profit growth: Comparative 4-year analysis
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Zachary J. Zimmermann, David V. Gauvin, Joshua D. Yoder, Theodore J. Baird, Jill A. Dalton, Mary Jeanne Kallman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

“INSPIRE”: A European training network in safety pharmacology creating opportunities for 15 PhD students
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Pieter-Jan Guns (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

SEND 3.1: A path to readiness for safety pharmacology study data
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Karla Lancaster (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Is enough, enough? SEND data processing considerations when changing the logging rate
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Kate Voss, Cory Appleby, Kenneth Kearney, Brian M. Roche (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Enhancing stem cell-based toxicity assays by engineering the culture niche in a high-throughput, assay-agnostic manner
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Nicholas A. Geisse, Jesse Macadangdang, Bonnie Berry, Rajneesh Jha, Kevin Gray, Alec S.T. Smith, Deok-Ho Kim (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Controlled large-scale manufacturing of hiPSC-derived cardiomyocytes in stirred-tank bioreactors for high-throughput safety assessment in drug discovery and development
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Tessa de Korte, Jessica Veenman, Karin Langenberg, Pieter van Loenen, Peter Nacken, Farbod Famili, Arie Reijerkerk (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Matthias Gossmann, Ulrich Thomas, Andras Horvath, Elena Dragicevic, Sonja Stoelzle-Feix, Niels Fertig, Alexander Jung, Aravind H. Raman, Manfred Staat, Peter Linder (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Evaluation of human induced pluripotent stem cell (hiPSC)—derived peripheral neurons as an in vitro model to screen for compounds that modulate neurite growth and stability
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Liang Guo, John Hamre, Sandy Eldridge, Ralph Parchment, Elizabeth Glaze (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Integrated analysis of human induced pluripotent stem cell-derived cardiomyocytes in diversity and disease modeling
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): David Majewski, Jing Liu, Souameng Lor, Giorgia Salvagiotto, Simon Hilcove, Eugenia Jones (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research