A/J mice are more susceptible than C57BL/6 to acetaminophen-induced hepatotoxicity
Publication date: Available online 22 March 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Lorena Bavia (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - March 22, 2021 Category: Drugs & Pharmacology Source Type: research

Strategies to encourage the adoption of social housing during cardiovascular telemetry recordings in non-rodents
Publication date: Available online 5 March 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Helen Prior, Mark Holbrook (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - March 5, 2021 Category: Drugs & Pharmacology Source Type: research

An immunoblot assay for cysteine oxidation by reactive oxygen species allows detection of novel thioprotective efficacy of black tea extracts
Publication date: Available online 23 February 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Philip C. Burcham, Julie Le, Louis Ma (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - February 24, 2021 Category: Drugs & Pharmacology Source Type: research

Genomics Integrated Systems Transgenesis (GENISYST) for gain-of-function disease modelling in Göttingen Minipigs
Publication date: Available online 18 February 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Joachim Maxeiner, Rahul Sharma, Carolin Amrhein, Frederic Gervais, Maria Duda, Jonathan Ward, Lars Friis Mikkelsen, Roy Forster, Michal Malewicz, Jaya Krishnan (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - February 20, 2021 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: January–February 2021Source: Journal of Pharmacological and Toxicological Methods, Volume 107Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - January 28, 2021 Category: Drugs & Pharmacology Source Type: research

Development of an easy and rapid analytical method for the extraction and preconcentration of chloroquine phosphate from human biofluids prior to GC–MS analysis
Publication date: Available online 24 January 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Süleyman Bodur, Sezin Erarpat, Ömer Tahir Günkara, Sezgin Bakırdere (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - January 25, 2021 Category: Drugs & Pharmacology Source Type: research

A new group housing approach for non-human primate metabolism studies
Publication date: Available online 9 January 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Ruth Stow, John Kendrick, Neil Ibbotson, Georgina Adjin-tettey, Beverley Murphy, Richard Trojca, James Miller, Gitte Konradsen, Kirstine Øvlisen, Hans Helleberg, Jesper Juhl Hansen (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - January 9, 2021 Category: Drugs & Pharmacology Source Type: research

Peanut butter as an alternative dose delivery method to prevent strain-dependent orogastric gavage-induced stress in mouse teratogenicity studies
Publication date: Available online 30 December 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Melanie R. Warren, Andreea Radulescu, Peter Dornbos, Danila Cuomo, Shelby Zumwalt, Diana Bueso-Mendoza, Megan Nitcher, John J. LaPres, David W. Threadgill (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - January 1, 2021 Category: Drugs & Pharmacology Source Type: research

LC-MS/MS method for rapid and accurate detection of caffeine in a suspected overdose case
Publication date: Available online 1 December 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Kiyotaka Usui, Yuji Fujita, Yoshito Kamijo, Yui Igari, Masato Funayama (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - December 2, 2020 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: November–December 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 106Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 18, 2020 Category: Drugs & Pharmacology Source Type: research

Evaluation of an in silico model APD prediction against 3 detection methods of delayed repolarization in hiPSC cardiomyocytes
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Steven K. Engle, Matthew M. Abernathy, Derek D. Best, Evan B. Wang, Thomas K. Baker, Derek J. Leishman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Validation of cardiac toxicity testing using in vitro methods of CiPA initiative
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Ki-Suk Kim (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Evaluating the impact of electrocardiogram analysis methods on the accurate identification of drug-induced changes to QT interval
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Nicholas Ether, Derek J. Leishman, Marc Bailie, Adam Lauver (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Does CiPA appropriately account for clinical exposure in predicting the risk of torsade de pointes?
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Derek J. Leishman, Matthew M. Abernathy, Evan B. Wang (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research

Towards an understanding of hERG potency variability derived from patch clamp protocols
Publication date: September 2020Source: Journal of Pharmacological and Toxicological Methods, Volume 105Author(s): Evan B. Wang, Derek J. Leishman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 2, 2020 Category: Drugs & Pharmacology Source Type: research