Cardiovascular assessments in juvenile monkeys using jacketed telemetry: Background data and the effects of heart rate on QT correction
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Nataliya Sadekova, Kevin Norton (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Telemetered left-ventricular pressure in Yucatan mini-pigs: Chronic evaluation in a novel genetic model of non-obstructed hypertrophic cardiomyopathy
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Beth Geist, Bradley L. Youngblood, Yukie Ueyama, Amanda LaRose, Robert Hamlin, Marc J. Evanchik, Carlos del Rio (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Evaluation of seizure liabilities of epileptogenic but non-convulsive agents in rats
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Simon Loiodice, Julien Modolo, Emilie Cayre, Anne-Sophie Denibaud, Bertrand Rion, Geoffrey Viardot, Philippe L'Hostis, Fabrice Wendling, Christophe Drieu La Rochelle (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

PhysioTel M-series telemetry is a viable alternative to jacketed telemetry for continuous cardiovascular data collection on toxicology studies
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): John Kremer, Kerry Kopelke, Alexandra Sielaff, Michael Taschwer, Jill Nichols (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Assessment of relative sensitivities of crossover and ascending-dose study designs for cardiovascular telemetry evaluation in cynomolgus monkeys
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Mark E. Sheffield, Kelly Ashcroft-Hawley (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Cardiovascular effects of RTR2996, a single stranded oligonucleotide, in the minipig
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Sonia Roberts, Andrea Greiter-Wilke, David Waiz, Roland Jenni, Christian Weile, Marco Zihlmann, Yann Tessier, Annamaria Braendli-Baiocco, Matthias Festag (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Comparison of different QTc formulae for correction of QT interval in cynomolgus monkeys
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Xinchao Xia, Rui Wu, Shanshan An, Rui Li, Sue Mcpherson (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Implementation of DSI FinePointe® whole body plethysmography method in freely moving rats
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Raafat Fares, Christophe Bory, Christophe Valgalier, Stephane Baudet (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Rodent respiratory findings with mGlu5 positive allosteric modulator RG7342, translation to non-rodent and man
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Theo Dinklo, David Waiz, Sonia Roberts, Stefan Sturm, Roland Jenni, Monika Aegler, Andrea Greiter-Wilke (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Evaluation of respiratory rate measurements derived from blood pressure waveforms in telemetered dogs
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Hai-Ming Tang (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Novel Methods for the Assessment of Safety Pharmacology and Toxicology Parameters in Anesthetized and Ventilated Dogs Receiving Inhaled Drugs
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Kim Bujold, Juergen Pfeiffer, Simon Authier, Richard Malcolmson, Jim Fink, Jeff Tepper (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

A role for the M1 muscarinic receptor in gastrointestinal motility
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Stephen Jenkinson, Lisa Nottebaum, Asser Bassyouni, John Lazzaro, Betty Pettersen, Jennifer Davoren (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Cardiovascular assessment during paired feeding in telemetry implanted monkeys
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Peter Harris, Philip Gerwin, Jennifer Colangelo, Corey Petrella, Isaac Rosado, Laura Singer, Ricardo Fernandez, Todd Wisialowski (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Computer-aided design of ECG telemetry systems for online cardiac monitoring
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Yaël Kolasa, Jean-Philippe Georges, Thierry Bastogne (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

The harm in harm benefit analysis terminology and safety pharmacology
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Lewis B. Kinter, Matt Terazi, Lou DeTolla, David K. Johnson (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research