Journal of Pharmacological and Toxicological Methods This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Translation of in vitro cannabinoid 1 receptor agonist activity to in vivo pharmacodynamic endpoints
Publication date: Available online 21 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Stephen Jenkinson, Susan M.G. Goody, Asser Bassyouni, Rhys Jones, Annie Otto-Bruc, Stephanie Duquennoy, Jamie K. DaSilva, Paul Butler, Andy Mead (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 21, 2020 Category: Drugs & Pharmacology Source Type: research

Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation
Publication date: Available online 12 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Eric I. Rossman, Frank Cools, Jason Cordes, Deborah Dhuyvetter, Jennifer M. Doyle, Gregory S. Friedrichs, Brian Guth, Moni B. Neradilek, Stanley T. Parish, Jennifer B. Pierson, Nayak Polissar, Hai-Ming Tang (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 12, 2020 Category: Drugs & Pharmacology Source Type: research

Dynamic features of cardiac vector as alternative markers of drug-induced spatial dispersion
Publication date: Available online 6 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Pablo Daniel Cruces, Drago Torkar, Pedro David Arini (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 7, 2020 Category: Drugs & Pharmacology Source Type: research

Inotropic Assessment in Engineered 3D Cardiac Tissues using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in the BiowireTM II Platform
Publication date: Available online 3 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Yusheng Qu, Nicole Feric, Isabella Pallotta, Rishabh Singh, Rooz Sobbi, Hugo M. Vargas (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 4, 2020 Category: Drugs & Pharmacology Source Type: research

Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment
Publication date: Available online 3 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Matthias Goßmann, Peter Linder, Ulrich Thomas, Krisztina Juhasz, Marta Lemme, Michael George, Niels Fertig, Elena Dragicevic, Sonja Stoelzle-Feix (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 4, 2020 Category: Drugs & Pharmacology Source Type: research

Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method
Publication date: Available online 3 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Mahnaz Maddah, Mohammad A. Mandegar, Keri Dame, Francis Grafton, Kevin Loewke, Alexandre J.S. Ribeiro (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 4, 2020 Category: Drugs & Pharmacology Source Type: research

Characterization of an i.p. D-galactose-induced cataract model in rats
Publication date: Available online 3 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Lei Zhong, Tao Wang, Ting Wang, Huanhuan Cheng, Juan Deng, Hui Ye, Weihua Li, Shiqi Ling (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 4, 2020 Category: Drugs & Pharmacology Source Type: research

Use of the Actiwatch-Mini® in dog safety studies as an early indicator for drug-induced behavioural changes
Publication date: Available online 3 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Frank Cools, Ivan Kopljar, Tekle Fetene, Herman Borghys (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 4, 2020 Category: Drugs & Pharmacology Source Type: research

Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes
Publication date: Available online 1 July 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Yoshiko Okai, Keiko Matsune, Kazunori Yamanaka, Toshikatsu Matsui, Emily Pfeiffer Kaushik, Kosuke Harada, Hiroshi Kohara, Akimitsu Miyawaki, Harushige Ozaki, Matthew Wagoner, Tadahiro Shinozawa (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 2, 2020 Category: Drugs & Pharmacology Source Type: research

Voltage-sensing optical recording: A method of choice for high-throughput assessment of cardiotropic effects
Publication date: Available online 21 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Stéphane Bedut, Ralf Kettenhofen, Jean-Marc D'Angelo (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 22, 2020 Category: Drugs & Pharmacology Source Type: research

A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model
Publication date: Available online 21 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Xiaomei Han, Mohammadreza Samieegohar, Bradley J. Ridder, Wendy W. Wu, Aaron Randolph, Phu Tran, Jiansong Sheng, Sonja Stoelzle-Feix, Nina Brinkwirth, Maria Giustina Rotordam, Nadine Becker, Søren Friis, Markus Rapedius, Tom A. Goetze, Tim Strassmaier, George Okeyo, James Kramer, Yuri Kuryshev, Caiyun Wu, David G. Strauss (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 21, 2020 Category: Drugs & Pharmacology Source Type: research

INSPIRE: A European training network to Foster research and training in cardiovascular safety pharmacology
Publication date: Available online 18 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Pieter-Jan D. Guns, Brian D. Guth, Stefan Braam, Georgios Kosmidis, Elena Matsa, Annie Delaunois, Vitalina Gryshkova, Sylvain Bernasconi, Harry Knot, Yair Shemesh, Alon Chen, Michael Markert, Miguel Fernandez, Damiano Lombardi, Céline Grandmont, Berta Cillero-Pastor, Ron M.A. Heeren, Wim Martinet, Jeanette Woolard, Matt Skinner (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 20, 2020 Category: Drugs & Pharmacology Source Type: research

Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment
Publication date: Available online 18 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Nina Brinkwirth, Kiyoshi Takasuna, Masafumi Doi, Nadine Becker, Alison Obergrussberger, Søren Friis, Hatsue Furukawa, Yuka Hasegawa, Takayuki Oka, Atsushi Ohtsuki, Niels Fertig, Sonja Stoelzle-Feix (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 20, 2020 Category: Drugs & Pharmacology Source Type: research

An improved two-step method for extraction and purification of primary cardiomyocytes from neonatal mice
Publication date: Available online 11 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Chengbao Li, Xuli Rong, Jing Qin, Sheng Wang (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 12, 2020 Category: Drugs & Pharmacology Source Type: research

Intrapulmonary inoculation of multicellular spheroids to construct an orthotopic lung cancer xenograft model that mimics four clinical stages of non-small cell lung cancer
Publication date: Available online 10 June 2020Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Yingbo Huang, Yifan Lu, Mallika Vadlamudi, Shen Zhao, Melanie Felmlee, Roshanak Rahimian, Xin Guo (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - June 10, 2020 Category: Drugs & Pharmacology Source Type: research