A Machine Learning Algorithm Predicting Risk of Dilating VUR Among Infants With Hydronephrosis Using UTD Classification
Urinary Tract Dilation (UTD) classification has been designed to be a more objective grading system to evaluate antenatal and post-natal UTD. Due to unclear association between UTD classifications to specific anomalies such as vesico-ureteral reflux (VUR), management recommendations tend to be subjective. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 8, 2023 Category: Urology & Nephrology Authors: Hsin-Hsiao Scott Wang, Michael Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow, Caleb Nelson Source Type: research

The Effect of Botulinum Toxin A in Children with Non-Neurogenic Therapy-Refractory Dysfunctional Voiding – A Systematic Review
Dysfunctional voiding (DV) is a habitual voiding disorder caused by involuntary contraction or non-relaxation of the external urethral sphincter (EUS) during voiding. This contraction causes high post-void residuals (PVR), urinary incontinence and urinary tract infections (UTIs). Various treatments for DV are available, but some children do not respond. Intersphincteric Botulinum Toxin-A (BTX-A) may be a possible treatment for therapy-refractory children with DV. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 7, 2023 Category: Urology & Nephrology Authors: S.A.A. Hoelscher, I.B. de Angst, Z. Buijnsters, W.M. Bramer, F. Akkermans, M. Kuindersma, J.R. Scheepe, L.A. ’t Hoen Tags: Review Article Source Type: research

Urethrocutaneous fistula and glans dehiscence formation of hypospadias surgery in patients receiving caudal block vs. non-caudal block: A meta-analysis
This meta-analysis aimed to evaluate the difference in postoperative complications as urethrocutaneous fistula or glans dehiscence, in children undergoing primary hypospadias repair with caudal block (CB) versus non-caudal block (NCB). (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 7, 2023 Category: Urology & Nephrology Authors: Yujie Xia, Zhenzhen Yang, Jiayi, Pei Liu, Honcheng Song, Ning Sun, Lijing Li, Weiping Zhang Tags: Review Article Source Type: research

What the editors are reading: social media
(Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 6, 2023 Category: Urology & Nephrology Authors: Diana Cardona-Grau, Christopher E. Bayne Tags: What the Editors are Reading Source Type: research

Response to commentary re "Quantification of vesicoureteral reflux using machine learning"
We sincerely appreciate the remarks provided throughout the review of our work. This is an additional impetus to continue our efforts in establishing uniform standardization of subjective scores, terminologies, and methodologies in the field of pediatric urology. We strongly hold the belief that this process of standardization is not only crucial but also offers a chance for the incorporation of artificial intelligence (AI) that could improve accuracy and uniformity in diagnosis and treatment strategies. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 4, 2023 Category: Urology & Nephrology Authors: Saidul Kabir, Muhammad E.H. Chowdhury, Tariq Abbas Tags: Letter to the Editor Source Type: research

Response to Commentary re  Quantification of Vesicoureteral Reflux using Machine Learning  Utilizing Artificial Intelligence to Enhance Objective Description in The Field of Pediatric Urology
We sincerely appreciate the remarks provided throughout the review of our work. This is an additional impetus to continue our efforts in establishing uniform standardization of subjective scores, terminologies, and methodologies in the field of pediatric urology. We strongly hold the belief that this process of standardization is not only crucial but also offers a chance for the incorporation of artificial intelligence (AI) that could improve accuracy and uniformity in diagnosis and treatment strategies. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 4, 2023 Category: Urology & Nephrology Authors: Saidul Kabir, Muhammad E.H. Chowdhury, Tariq Abbas Tags: Letter to the Editor Source Type: research

Commentary to “Heresy - Is there a role for ultrasound in management of the non-palpable testicle?”
This study entitled “Heresy - Is There a Role for Ultrasound in Management of the Non-Palpable Testicle?” by Press et al. undertakes a retrospective examination of the utilization of pre-operative ultrasound in the context of non-palpable cryptorchidism, a topic of considerable interest and one that engenders cont roversy concerning the recommendations set forth in the American Urological Association (AUA) cryptorchidism guidelines [1,2]. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Michael E. Chua, Martin A. Koyle Source Type: research

Commentary to “Decreased percent change in renal pelvis diameter on diuretic functional magnetic resonance urography following administration of furosemide may help characterize unilateral uretero-pelvic junction obstruction”
The authors present an MRI-based study examining renal pelvis expansion as a response to diuresis, the first such paper pairing this modality and metric [1]. Pelvis expansion is interesting, in part as renal pelvic size change behaves so differently as an absolute number and as a percentage. There are three clinical circumstances to which diuretic fMRU could be applied: dilated/obstructed, dilated/not obstructed, and not dilated. In terms of how compliant the systems are in absolute increase in size after lasix, the dilated/not obstructed group distended the most, followed by the dilated/obstructed group, followed by the n...
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Michael P. Kurtz Source Type: research

Does KUB play a role in the diagnosis of bladder bowel dysfunction?
Kidney ureter bladder radiography (KUB) is widely used for the evaluation of constipation in children with bladder and bowel dysfunction (BBD); however, there is varying evidence to support its routine diagnostic use. One drawback to KUB is radiation exposure. The dangers of radiation in children are well-documented, and per As Low As Reasonably Achievable, non-beneficial radiation should be avoided. This risk is especially high in children who undergo repeated imaging in the follow up of constipation treatment. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Alexandra R. Siegal, Megan Paul, Neha R. Malhotra, Erin Miller, Patrick Ho, Joy Masseaux, Eva M. Baldisserotto, J. Antonio Quiros, Fernando A. Ferrer Source Type: research

Commentary to Quantification of Vesicoureteral Reflux using Machine Learning
The authors have taken on an incredibly difficult task with this paper as they try to apply a relatively nascent technology to facilitate and simplify clinical decision making in vesicoureteric reflux1. Radiological findings can often pose a diagnostic dilemma not only in treatment for paediatric urologists, but important in risk stratification and communication with parents/caregivers. Not unsurprisingly, this is usually not at the extremes of IRCC grading but in the subjective grey areas of Grade 2 vs 3, or Grade 3 vs 4. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Fardod O ’Kelly Source Type: research

Review comment on: Decreased Percent Change in Renal Pelvis Diameter on Diuretic Functional Magnetic Resonance Urography Following Administration of Furosemide May Help Characterize Unilateral Uretero-Pelvic Junction Obstruction
The authors present an MRI-based study examining renal pelvis expansion as a response to diuresis, the first such paper pairing this modality and metric1. Pelvis expansion is interesting, in part as renal pelvic size change behaves so differently as an absolute number and as a percentage. There are three clinical circumstances to which diuretic fMRU could be applied: dilated/obstructed, dilated/not obstructed, and not dilated. In terms of how compliant the systems are in absolute increase in size after lasix, the dilated/not obstructed group distended the most, followed by the dilated/obstructed group, followed by the non-...
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Michael P. Kurtz Source Type: research

Response to Commentary re Decreased Percent Change in Renal Pelvis Diameter on Diuretic Functional Magnetic Resonance Urography Following Administration of Furosemide May Help Characterize Unilateral Uretero-Pelvic Junction Obstruction
We would like to thank you for your thoughtful commentary and insightful feedback. The comment to the editor you provided summarizes the findings of our study quite nicely. We utilized fMRU (functional Magnetic Resonance Urography) to analyze renal pelvis expansion in patients with congenital hydronephrosis following diuretic administration. The study found that non-obstructive hydronephrosis resulted in nearly double the renal pelvis expansion compared to obstructive hydronephrosis following furosemide administration. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Leann Linam, Joo Cho, Andrew Kirsch, Karmon Janssen Tags: Letter to the Editor Source Type: research

Commentary to “Heresy - Is There a Role for Ultrasound in Management of the Non- palpable Testicle?”
This study entitled "Heresy - Is There a Role for Ultrasound in Management of the Non-Palpable Testicle?" by Press et al undertakes a retrospective examination of the utilization of pre-operative ultrasound in the context of non-palpable cryptorchidism, a topic of considerable interest and one that engenders controversy concerning the recommendations set forth in the American Urological Association (AUA) cryptorchidism guidelines (1,2). (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Michael Chua, Martin A. Koyle Source Type: research

Response to Commentary to Heresy - Is There a Role for Ultrasound in Management of the Non Palpable Testicle?
In 1986, we published a paper stating that ultrasound was not as accurate as a careful physical exam in detecting an undescended testis. (1) This was true then, but with continued improvements in ultrasound technology, with ever higher frequency transducers allowing for increased contrast resolution, ultrasound is now able to reliably detect testes located just proximal to the internal ring or in the pelvis behind the bladder. This technologic improvement and the findings of our study will not affect the management of those urologists who prefer laparoscopy for the first step in management of all non-palpable undescended t...
Source: Journal of Pediatric Urology - November 3, 2023 Category: Urology & Nephrology Authors: Robert M. Weiss Tags: Letter to the Editor Source Type: research

Enlarged prostatic utricle and vagina masculinus
I have read with interest the manuscript written by Guirguis et al. [1] entitled “ Insights Into Enlarged Prostatic Utricles And Müllerian Duct System Remnants Associated With Posterior Hypospadias”. I would respectfully disagree with the authors on some points. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - November 2, 2023 Category: Urology & Nephrology Authors: Smail Acimi Tags: Letter to the Editor Source Type: research