Reducing resource utilization for patients with uncomplicated appendicitis through use of same-day discharge and elimination of postoperative antibiotics
There is controversy over certain aspects of post-appendectomy care for children with uncomplicated appendicitis. Some institutions have embraced the practice of same-day discharge after appendectomy, while others are hesitant due to concerns about increased readmissions or emergency department (ED) visits. Similarly, some surgeons have transitioned to treating gangrenous appendicitis with a single perioperative dose, while others are concerned about increased risk of infection in this population. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 29, 2020 Category: Surgery Authors: Courtney L. Devin, Roshan D'Cruz, Allison F. Linden, Sharon English, Charles D. Vinocur, Kirk W. Reichard, Loren Berman Source Type: research

Outcomes in the giant omphalocele population: A single center comprehensive experience
Morbidity and mortality in the giant omphalocele population is complicated by large abdominal wall defects, physiologic aberrancies, and congenital anomalies.We hypothesized different anomalies and treatment types would affect outcomes. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 28, 2020 Category: Surgery Authors: Heather R. Nolan, Monica L. Wagner, Todd Jenkins, Foong-Yen Lim Source Type: research

Surgical tray reduction for cost saving in pediatric surgical cases: A qualitative systematic review
Standardization of surgical instrument trays and doctor preference cards (DPC) are known to reduce the cost of adult surgical cases. The practice in pediatric surgery may be more complex owing to a wide range of patient age, leading to difficulty with practice implementation and loss of potential financial savings, which underscore the importance of the review of this topic. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 27, 2020 Category: Surgery Authors: Charlene Dekonenko, Tolulope A. Oyetunji, Rebecca M. Rentea Source Type: research

Making the diagnosis of midgut volvulus: Limited abdominal ultrasound has changed our clinical practice
To assess the diagnostic accuracy of limited abdominal ultrasound (US) examination for midgut volvulus (MGV) and to evaluate how clinical practice has changed in a free-standing children's hospital leading to the near obsolescence of upper GI (UGI) studies for the diagnosis of MGV. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 26, 2020 Category: Surgery Authors: Kevin Wong, Dane Van Tassel, Justin Lee, Robert Buchmann, Monique Riemann, Craig Egan, Mostafa Youssfi Source Type: research

Development of a multidisciplinary colorectal and pelvic health program: Program implementation and clinical impact
Pediatric patients with complex colorectal and genitourinary conditions often require coordinated multidisciplinary care; however, this coordinated care can be hard to structure and deliver. The purpose of this paper is to review the development and implementation of a multidisciplinary colorectal and pelvic health program, one year after the program's initiation. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 26, 2020 Category: Surgery Authors: Candace C. Style, Danielle M. Hsu, Mariatu A. Verla, Angela G Mittal, Paul Austin, Abhishek Seth, Jennifer E. Dietrich, Oluyemisi A Adeyemi-Fowode, Jennifer L. Bercaw-Pratt, Eric H. Chiou, Bruno P. Chumpitazi, Amaka Akalonu, Veronica A. Victorian, Felicia Source Type: research

Gastroschisis in the neonatal period: A prospective case-series in a Brazilian referral center
We describe the clinical and surgical characteristics of gastroschisis patients in a Brazilian referral center. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Bianca M.R. Martins, Isabel Abreu, Maria Dalva B. M éio, Maria Elisabeth L. Moreira Source Type: research

Evaluation of nebulized N-acetyl cysteine in outcome of esophageal atresia with tracheoesophegeal fistula
To evaluate the role of nebulized N-acetyl cysteine (NAC) in liquefying the airway secretions and improving the outcome of patients of esophageal atresia with tracheoesophageal fistula (EA  + TEF). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Gurmeet Singh, Anand Pandey, Gaurav Shandilya, Archika Gupta, JD Rawat, Ashish Wakhlu, SN Kureel Source Type: research

Accuracy of contrast swallow study in assessment of caustic esophageal stricture length in children: Agreement study
Caustic esophageal stricture length assessment is essential for planning endoscopic management and predicting its prognosis. We aimed to assess the accuracy of contrast swallow study (CSS) in measuring stricture length in comparison to endoscopy (definitive investigation for actual length measurement). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Khaled M. El-Asmar, Allam Elsayed Allam, Ayman M. Allam Source Type: research

Physician perspectives on discussions with parents of infants with suspected ureteropelvic junction obstruction
The purpose of this study was to understand pediatric urologists' perceived role of patient characteristics on discussions about treatment of infants with suspected UPJ obstruction. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Vijaya M. Vemulakonda, Allison Kempe, Mika K. Hamer, Megan A. Morris Source Type: research

Gastrointestinal trichobezoar: An experience with 17 cases
Trichobezoar is an exceedingly rare entity in children and mimics other chronic ailments such as abdominal tuberculosis or malignancy. Delayed diagnosis and management result in various complications. The study was conducted to describe our experience with 17 consecutive cases of gastrointestinal tract (GIT) trichobezoars. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Muhammad Bilal Mirza, Nabila Talat, Muhammad Saleem Source Type: research

Totally implantable venous access ports: A prospective randomized study comparing subclavian and internal jugular vein punctures in children
Totally implantable venous access ports (TIVAPs) are essential in children who require long-term intermittent intravenous therapy. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 25, 2020 Category: Surgery Authors: Liling Han, Jun Zhang, Xiaobing Deng, XiangRu Kong, Chao Yang, Liang Peng, Chunyan Kou, Ke Zou, LinYa Lv, ChangChun Li, Shan Wang, GuangHui Wei Tags: Original articles Source Type: research

Contemporary postoperative imaging practices among pediatric surgeons for image-guided central venous line placement: A survey of the American Pediatric Surgical Association
Rare life-threatening complications after central venous line (CVL) placement in children may encourage the routine use of postoperative imaging, despite multiple studies demonstrating the limited utility of this practice. The aim of this study was to investigate the nature of this discordance. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 23, 2020 Category: Surgery Authors: Aaron J. Cunningham, Sanjay Krishnaswami, Stephanie Radu, Nicholas A. Hamilton Source Type: research

Considerations for the outpatient practice in pediatric surgery during the novel SARS-CoV-2 pandemic
The SARS-CoV-2 (COVID-19) pandemic has traveled the world without respect for geographic borders and impacted the lives of nearly every human soul on the planet. The novel virus responsible for this pandemic usually results in little to no symptoms in the pediatric population [1,2]. This makes children nearly the perfect natural reservoir for the spread of COVID-19. Unfortunately, the older human population does not tolerate infection with COVID-19 nearly as well with morbidity and mortality that increases with age and medical comorbidities [3 –6]. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 21, 2020 Category: Surgery Authors: Michael V. Tirabassi Source Type: research

Development of a prediction model for postoperative complications after primary hypospadias correction
To develop a prediction model for postoperative complications after primary one-stage hypospadias correction to improve preoperative parental counseling. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 19, 2020 Category: Surgery Authors: Elisabeth MJ Dokter, Loes FM van der Zanden, Susanne JM Laumer, Priya Vart, Barbara BM Kortmann, Robert PE de Gier, Wout FJ Feitz, Nel Roeleveld, Iris ALM van Rooij Source Type: research

Difficulties classifying myasthenia gravis in the pediatric surgical literature
We read with interest the manuscript by Derderian et al. [1], and we support their enthusiasm for thymectomy for myasthenia gravis (MG), particularly with respect to minimally invasive techniques. However, we write to register our disappointment with their use of Osserman staging and deFilippi treatment classification, both of which are qualitative in nature and should not be mainstays of contemporary MG literature. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 19, 2020 Category: Surgery Authors: Seth D. Goldstein, Nancy L Kuntz Source Type: research

Gastric pull-up by the retrosternal route for esophageal replacement: Feasibility in a limited-resource scenario
The authors herein report the results of esophageal replacement by gastric pull-up technique through the retrosternal route as an option for esophageal replacement in a resource-constrained setup. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 19, 2020 Category: Surgery Authors: Samir Kant Acharya, Nidhi Sugandhi, Amit Kumar Jadhav, Deepak Bagga, Narinder Tekchandani, Anjana Sreedharan, Saurav Srivastav, Goutam Chakraborty, Prabudh Goel Tags: Original Article Source Type: research

When to consider a posterolateral descending aortopexy in addition to a posterior tracheopexy for the surgical treatment of symptomatic tracheobronchomalacia
The descending thoracic aorta typically crosses posterior to the left mainstem bronchus (LMSB). We sought to evaluate patient factors that may lead one to consider a posterolateral descending thoracic aortopexy (PLDA) in addition to a posterior tracheopexy (PT) in the surgical treatment of symptomatic tracheobronchomalacia (TBM) that involves the LMSB. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 19, 2020 Category: Surgery Authors: Wendy Jo Svetanoff, Benjamin Zendejas, Leah Frain, Gary Visner, Charles J. Smithers, Christopher W. Baird, Sanjay P. Prabhu, Russell W. Jennings, Thomas E. Hamilton Source Type: research

Comparison of meatal-based flap (Mathieu) and tubularized incised-plate (TIP) urethroplasties for primary distal hypospadias: A systematic review and meta-analysis
We conducted this meta-analysis to compare postoperative outcomes between meatal-based flap (Mathieu) and tubularized incised plate (TIP) techniques for distal hypospadias. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 18, 2020 Category: Surgery Authors: Yuanfeng Zhang, Zeren Shen, Xinye Zhou, Zepai Chi, Xuwei Hong, Yi Huang, Hong Huang, Shaochuan Chen, Kaijian Lan, Jiahua Lin, Weichu Wu, Yizhou Zhou, Yonghai Zhang Source Type: research

Reply to Letter to the Editor
We wish to thank Dr. Jahoorahmad Patankar for his interest in our manuscript. Complications that included infections, reoperations, and granuloma were detailed in the report. Both groups were at risk for these complications. There were no complications attributable to the use of laparoscopy, including vascular/bowel injury, port site incisional hernia, or incarcerated omentum. There were no patients who required conversion to an open operation due to inability to complete the repair. A few patients required the use of a 2  mm Maryland dissector placed via a stab incision to assist in the repair due to the redundancy of t...
Source: Journal of Pediatric Surgery - May 16, 2020 Category: Surgery Authors: Albert J Chong, Lisa Herrinton, Helene Fevrier Tags: Correspondence Source Type: research

Association of number and type of serious complications with failure to rescue in children undergoing surgery: A NSQIP-Pediatric analysis
This study aims to determine the FTR rate in a pediatric surgical population, and if number (1 or 2+) and type of serious complications are associated with FTR. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 16, 2020 Category: Surgery Authors: Soojin Kim, Lauren Balmert, Mehul V. Raval, Emilie K. Johnson, Fizan Abdullah, David I. Chu Source Type: research

Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population
Hirschsprung disease (HSCR) is a neurodevelopmental disorder with a strong genetic component. Common variants of NRG1 contributed to HSCR risk in Asians, and rare variants of ERBB2 and ITGB4 were found to be associated with HSCR. ERBB2 and ITGB4 are partners of Nrg1/ErbB pathway, which is important in HSCR pathogenesis. We aimed to investigate whether common variants in NRG1, ERBB2 and ITGB4 were associated with HSCR in Chinese Han population. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 14, 2020 Category: Surgery Authors: Zhiliang Wei, Xianxian Yu, Wenjie Wu, Meirong Bai, Yanjiao Lu, Huanlei Song, Yiming Gong, Beilin Gu, Xun Chu, Wei Cai Source Type: research

Pan-enteric neuropathy and dysmotility are present in a mouse model of short-segment Hirschsprung disease and may contribute to post-pullthrough morbidity
Hirschsprung disease (HSCR) is characterized by distal intestinal aganglionosis. While surgery is lifesaving, gastrointestinal (GI) motility disorders persist in many patients. Our objective was to determine whether enteric nervous system (ENS) abnormalities exist in the ganglionated portions of the GI tract far proximal to the aganglionic region and whether these are associated with GI dysmotility. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 12, 2020 Category: Surgery Authors: Sukhada Bhave, Emily Arciero, Corey Baker, Wing Lam Ho, Richard A. Guyer, Ryo Hotta, Allan M. Goldstein Source Type: research

Limb sparing surgery with vascular reconstruction for nonrhabdomyosarcoma soft tissue sarcoma in infants: A novel solution using allogenic vein graft from the parent
Surgery continues to remain an integral component of treatment, especially for nonrhabdomyosarcoma soft tissue sarcoma as compared to rhabdomyosarcoma owing to their general insensitivity to chemotherapy. A key determinant of outcomes, particularly for extremity tumors includes complete tumor resection with negative margins; however, a significant limitation for limb salvage surgery is the adherence of sarcomas to vital vascular structures. Hitherto, vascular involvement constituted an adequate reason for amputation. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 11, 2020 Category: Surgery Authors: Sajid S Qureshi, Suresh M, Jayesh Dhareshwar, Vasundhara Smriti Tags: Operative Techniques Source Type: research

Postfundoplication retching: Strategies for management
Retching is a common symptom in children following antireflux surgery, particularly in those with neurodisability. There is now a strong body of evidence that implicates retching as a major cause of wrap breakdown. Retching is not a symptom of gastroesophageal reflux disease; it is a component of the emetic reflex. In addition to causing wrap breakdown, it is indicative of the presence of nausea. It is a highly aversive experience and warrants treatment in its own right. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 11, 2020 Category: Surgery Authors: Catherine A. Richards Source Type: research

Lymph node yield in pediatric, adolescent and young adult Renal Cell Carcinoma – How many are enough?
The objective is to describe a LN yield threshold to quantify the chance of missing occult LN involvement at ≤10% in PAYAs with RCC. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 11, 2020 Category: Surgery Authors: Amanda F. Saltzman, Derek E. Smith, Dexiang Gao, Nicholas G. Cost Source Type: research

Ketorolac after colectomy for ulcerative colitis in children: An analysis of opioid utilization and postoperative complications
Enhanced recovery protocols include multimodal perioperative pain control and frequently include use of NSAIDs. There is conflicting evidence that ketorolac use in inflammatory bowel disease (IBD) may precipitate disease flares and postoperative complications. The outcomes of children who receive ketorolac in this setting are not well known. We sought to evaluate ketorolac utilization in children following colectomy for ulcerative colitis. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 10, 2020 Category: Surgery Authors: Mark A. Taylor, William B. West, Stephen L. Guthery, Mark Deneau, Scott S. Short Source Type: research

Minimally invasive surgery for pediatric renal tumors: A systematic review by the APSA Cancer Committee
Minimally invasive nephrectomy is performed routinely for adult renal tumors and for many benign pediatric conditions. Although open radical nephroureterectomy remains the standard of care for Wilms tumor and most pediatric renal malignancies, there are an increasing number of reports of minimally invasive surgery (MIS) for those operations as well. The APSA Cancer Committee performed a systematic review to better understand the risks and benefits of MIS in pediatric patients with renal tumors. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 6, 2020 Category: Surgery Authors: Marcus M. Malek, Christopher A. Behr, Jennifer H. Aldrink, Roshni Dasgupta, Todd E. Heaton, Alison Gehred, Timothy B. Lautz, Reto M. Baertschiger, Emily R. Christison-Lagay, Elisabeth T. Tracy, Daniel S. Rhee, David Rodeberg, Mary T. Austin, Peter F. Ehrl Source Type: research

Thoracic versus abdominal approach to correct diaphragmatic eventration in children
We read with interest the article ‘Thoracic versus abdominal approach to correct diaphragmatic eventration in children’ by Alisha Gupta et al. [1]. We congratulate the authors for publication of their study. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 4, 2020 Category: Surgery Authors: Jayakumar TK, KirtiKumar J Rathod, Manish Pathak Source Type: research

Diagnostic accuracy of serum alpha-fetoprotein levels in diagnosing recurrent sacrococcygeal teratoma: A systematic review
The incidence of children developing recurrent sacrococcygeal teratoma (SCT) is 2 –35%. Serum alpha-fetoprotein (AFP) is often used as a tumor marker for (malignant) recurrences of SCT and could potentially be used during routine follow-up after SCT resection. However, the diagnostic accuracy of serum AFP levels during follow-up has not been well established. Therefore, we aime d to systematically review the diagnostic accuracy of serum AFP levels in recurrent SCT. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 3, 2020 Category: Surgery Authors: L.J. van Heurn, M.M. Knipscheer, J.P.M. Derikx, L.W.E. van Heurn Source Type: research

Relationship between volume and outcome for surgery on congenital diaphragmatic hernia: A systematic review
Congenital diaphragmatic hernia (CDH) is a rare and life-threatening anomaly that needs surgical therapy after clinical stabilization of the neonate. Given an existing volume-outcome relationship for other high-risk, low volume procedures, we aimed at examining the relationship between hospital or surgeon volume and outcomes for surgery on CDH. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 3, 2020 Category: Surgery Authors: Johannes Morche, Tim Mathes, Anja Jacobs, Barbara Pietsch, Lucas Wessel, Sabine Gruber, Edmund A.M. Neugebauer, Dawid Pieper Tags: Review Article Source Type: research

Long-term follow-up of pediatric open and laparoscopic inguinal hernia repair
We read with interest the article “Long-term follow-up of pediatric open and laparoscopic inguinal hernia repair” by Chong AJ, Fevrier HB, Herrinton L, [1] published in the J Pediatr Surg 2019;54:2138–44 (https://www.jpedsurg.org/article/S0022-3468(19)30120-4/fulltext). This is a long awaited study since the early days of usin g laparoscopy for pediatric inguinal hernia repairs in the late 1990s. I have some questions and a comment in regard to the article. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 3, 2020 Category: Surgery Authors: Jahoorahmad Z. Patankar Tags: Correspondence Source Type: research

Table of Contents
(Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 1, 2020 Category: Surgery Source Type: research

Announcements of Future Meetings
(Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 1, 2020 Category: Surgery Source Type: research

From the editors: The COVID-19 crisis and its implications for pediatric surgeons
“…….and there are no more surgeons, urologists, orthopedists…we are only doctors who suddenly become part of a single team to face this tsunami that has overwhelmed us…”.Dr. Daniele Macchine, Bergamo, Italy, March 9th, 2020 (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 28, 2020 Category: Surgery Authors: Mark Davenport, Mikko P. Pakarinen, Paul Tam, Pablo Laje, George W. Holcomb Tags: Editorial Source Type: research

STEP improves long-term survival for pediatric short bowel syndrome patients: A Markov decision analysis
Increasingly, for pediatric patients with short bowel syndrome (SBS), intestinal lengthening procedures such as serial transverse enteroplasty (STEP) are being offered with the hope of improving patients ’ chances for achieving enteral autonomy. However, it remains unclear to what extent STEP reduces the long-term need for intestinal transplant or improves survival. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 25, 2020 Category: Surgery Authors: RA Choudhury, D Yoeli, HB Moore, K Prins, M Kovler, SD Goldstein, SG Holland-Cunz, M Adams, JP Roach, TL Nydam, RN Vuille-dit-Bille Source Type: research

Should the search for ganglia in the distal rectal fistula in patients with anorectal malformation be abandoned?
Occurrence of Hirschsprung ’s disease in anorectal malformation (ARM) patients is rare, but many surgeons still ask to pathologists to search for ganglia in the terminal rectum/fistula; the histological procedure is time and money consuming and the results confounding. A consecutive series of ARM patients, in which the pres ence of ganglia in terminal rectum was revised, is herein presented. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 25, 2020 Category: Surgery Authors: Paola Midrio, Emanuele Trovalusci, Cinzia Zanatta, Ivana Cataldo Source Type: research

Alternative approaches to retroperitoneal lymph node dissection for paratesticular rhabdomyosarcoma
The aim of this study was to evaluate outcomes based on surgical approach for retroperitoneal lymph node dissection (RPLND) in patients with paratesticular rhabdomyosarcoma (PT-RMS). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 25, 2020 Category: Surgery Authors: Sara A. Mansfield, Andrew J. Murphy, Lindsay Talbot, Hasmukh Prajapati, Vinod Maller, Alberto Pappo, Sunil Singhal, Matthew J. Krasin, Andrew M. Davidoff, Abdelhafeez Abdelhafeez Source Type: research

Prenatal low-dose endotoxin exposure prolongs intestinal epithelial activation after birth and contributes to necrotizing enterocolitis
To investigate the effects of low dose endotoxin on transcriptional activity in intestinal epithelium, and its role in necrotizing enterocolitis (NEC). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 19, 2020 Category: Surgery Authors: Hong-yi Zhang, Fang Wang, Xinrao Meng, Chenzhao Feng, Lei Xiang, Gail E. Besner, Jie-xiong Feng Source Type: research

Inguinal hernia in girls: A retrospective analysis of over 1000 patients
This study assesses the incidence of ovarian strangulation and AIS, and its associated risk factors. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 18, 2020 Category: Surgery Authors: Kelly MA Dreuning, Rinse W Barendsen, AS Paul van Trotsenburg, Jos WR Twisk, Christien Sleeboom, LW Ernest van Heurn, Joep PM Derikx Source Type: research

The implication of intestinal bacterial translocation in central line associated blood stream infections in the pediatric population
Bacterial intestinal translocation plays an important role in neonatal sepsis. We aimed to elucidate the importance of such translocation in causing central line associated blood stream infection (CLABSI) in patients undergoing gastrointestinal surgery (GIS). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 16, 2020 Category: Surgery Authors: Fuad C. Haddad, Raghavendra Rao, Sandeep Kaur, Jaime Redkey, Adam Karcz, Alan P. Ladd Source Type: research

De novo somatic mutations and KRAS amplification are associated with cholangiocarcinoma in a patient with a history of choledochal cyst
Choledochal cysts are congenital dilations of the bile ducts, and are associated with an increased risk of malignant transformation. The purpose of this study is to report the outcomes of a large series of patients with choledochal cysts and to highlight our analysis of one patient who developed malignancy after cyst resection. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 12, 2020 Category: Surgery Authors: Marisa E. Schwab, Hanbing Song, Aras Mattis, Andrew Phelps, Lan T. Vu, Franklin W. Huang, Amar Nijagal Source Type: research

Single-site retroperitoneoscopy in pediatric metastatic lymphadenopathy
Retroperitoneoscopic surgery (RS) is increasingly used for the diagnosis, staging, and treatment of solid tumors, but rarely in pediatric surgical oncology for retroperitoneal lymph node dissection (RPLND). Herein, we use single-site RS for RPLND in children and compare the perioperative outcomes with those for the transperitoneal laparoscopic approach (TPLA). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Yousef El-Gohary, Sara Mansfield, Lindsay Talbot, Andrew J. Murphy, Andrew M. Davidoff, Abdelhafeez Abdelhafeez Source Type: research

Congenital short bowel syndrome: systematic review of a rare condition
Congenital short bowel syndrome (CSBS) is a rare gastrointestinal disorder caused by intrauterine reduction of small bowel length whose etiology is still unknown. Chronic diarrhea, vomiting, and failure to thrive are the most important complications, arising from less absorptive intestinal surface. This review examines clinical features and outcomes of CSBS patients. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Elisa Negri, Riccardo Coletta, Antonino Morabito Source Type: research

Gastroschisis prevalence substantially decreased from 2009 through 2018 after a 3-fold increase from 1997 to 2008
Gastroschisis incidence increased 300% in the United States from 1998 to 2013. We sought to assess trends in gastroschisis prevalence in the United States from 1997 to 2018 from a large NICU dataset. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Reese H. Clark, John Sousa, Matthew M. Laughon, Veeral N. Tolia Source Type: research

A pitfall of using general equivalence mappings to estimate national trends of surgical utilization for pediatric patients
General equivalence mappings (GEMs) were developed to facilitate a transition from International Classification of Diseases, Ninth Revision (ICD-9) to ICD, Tenth Revision (ICD-10). Validation of GEMs is suggested as coding errors have been reported for adult populations. The purpose of this study was to illustrate limitations of the GEMs for pediatric surgical procedures. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Yao Tian, Martha-Conley E. Ingram, Mehul V. Raval Source Type: research

US decennial census: Why the pediatric surgical community should be invested
The views expressed in this letter are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States Government. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Christian S. McEvoy, Robert L. Ricca Tags: Correspondence Source Type: research

Correspondence from Northern Italy about our experience with COVID-19
Facing the emergency of COVID-19 in one of the first red zones in Italy, we would like to remark about the significant impact that this infection brought to our Departments of Pediatric Surgery/Urology in our hospital (Fondazione IRCCS Ca ’ Granda Ospedale Maggiore Policlinico, Milano). We hope that our message will help other hospitals facing this world emergency. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 8, 2020 Category: Surgery Authors: Ernesto Leva, Anna Morandi, Angelo Sartori, Francesco Macchini, Alfredo Berrettini, Gianantonio Manzoni Tags: Correspondence Source Type: research

Do social circumstances dictate a change in the setup of an anorectal malformation clinic?
To assess the number of patients seen at the colorectal clinic of a low-to-middle income-country with emphasis on their social circumstances. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 6, 2020 Category: Surgery Authors: Giulia Brisighelli, Jerome Loveland, Catterina Bebington, Lindiwe Dyamara, Giasmin Ferrari, Christopher Westgarth-Taylor Source Type: research

Human skin-derived precursor cells xenografted in aganglionic bowel
One in 5000 newborns is diagnosed with Hirschsprung disease each year in the United States. The potential of employing neural crest stem cells to restore the enteric nervous system has been investigated. Skin-derived precursor cells (SKPs) are multipotent progenitor cells that can differentiate into neurons and gliocytes in vitro and generate enteric ganglion-like structures in rodents. Here we examined the behavior of human SKPs (hSKPs) after their transplantation into a large animal model of colonic aganglionosis. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 4, 2020 Category: Surgery Authors: Anne-Laure Thomas, Jordan S. Taylor, James C.Y. Dunn Source Type: research

Is thoracoscopic esophageal atresia repair safe in the presence of cardiac anomalies?
Esophageal atresia (EA) is often associated with congenital heart disease (CHD). Repair of EA by the thoracoscopic approach places physiological stress on a newborn with CHD. This paper reviews the outcomes of infants with CHD who had undergone thoracoscopic EA repair, comparing their outcomes to those without CHD. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - April 3, 2020 Category: Surgery Authors: Erika Fernandes, Amanda Kusel, Stephen Evans, James Houghton, James K. Hamill Source Type: research