A partial hemiresurfacing preliminary study of a novel magnetic resonance imaging–compatible polyetheretherketone mini-prosthesis for focal osteochondral defects
Publication date: Available online 20 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Xiangchao Meng, Wei Zhang, Zhiguo Yuan, Jun Chen, Zhuocheng Lyu, You Wang (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 21, 2020 Category: Orthopaedics Source Type: research

Gastrin for prevention of steroid-associated osteonecrosis in rats
Publication date: Available online 11 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Yaping Luo, Yingying Li, Chunting Hu, Jinglong Wang, Ling Qin, Guohui Fu, Shihui Chen (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 12, 2020 Category: Orthopaedics Source Type: research

Computational optimization of screw orientations for improved locking plate fixation of proximal humerus fractures
Publication date: Available online 7 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Dominic Mischler, Markus Windolf, Boyko Gueorguiev, Stefaan Nijs, Peter Varga (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 8, 2020 Category: Orthopaedics Source Type: research

Suprascapular nerve injury affects rotator cuff healing: A paired controlled study in a rat model
Publication date: Available online 5 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Yucheng Sun, Jae-Man Kwak, Youlang Zhou, Yan Fu, Zhe Wang, Qingzhong Chen, In-Ho Jeon (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 6, 2020 Category: Orthopaedics Source Type: research

The clinical use of the enriched bone marrow obtained by selective cell retention technology in treating adolescent idiopathic scoliosis
Publication date: Available online 5 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Peng Yang, Junchao Xing, Beike Chen, Fei Luo, Zehua Zhang, Jianzhong Xu, Tianyong Hou (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 6, 2020 Category: Orthopaedics Source Type: research

Finite element analysis of subtalar joint arthroereisis on adult-acquired flexible flatfoot deformity using customized sinus tarsi implant
Publication date: Available online 5 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Duo W.-C. Wong, Yan Wang, Wenxin Niu, Ming Zhang (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 6, 2020 Category: Orthopaedics Source Type: research

Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications
Publication date: Available online 2 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Anna I. Shiel, Wayne N. Ayre, Ashley W. Blom, Keith Hallam, Peter J. Heard, Oliver Payton, Loren Picco, Jason P. Mansell (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 3, 2020 Category: Orthopaedics Source Type: research

Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds
Publication date: Available online 3 March 2020Source: Journal of Orthopaedic TranslationAuthor(s): Pinghui Zhou, Genglei Chu, Zhangqin Yuan, Huan Wang, Weidong Zhang, Yingji Mao, Xuesong Zhu, Weiguo Chen, Huilin Yang, Bin Li (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 3, 2020 Category: Orthopaedics Source Type: research

Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomized rats
Publication date: Available online 28 February 2020Source: Journal of Orthopaedic TranslationAuthor(s): Ling Li, Xiaomin Yi, Cuishan Huang, Keda Shi, Jiani Wang, Qingqiang Zeng, Wenxiang Cheng, Xiangjiu He, Peng Zhang, Guixing Qiu, Ling Qin, Xinluan Wang (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - March 1, 2020 Category: Orthopaedics Source Type: research

Urinary miRNAs as biomarkers for idiopathic osteonecrosis of femoral head: A multicentre study
ConclusionsThe levels of urinary miRNAs are valuable biomarkers for idiopathic ONFH. Given the noninvasive nature of this test, it is potentially useful for diagnosis and monitoring of idiopathic ONFH progression. (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - February 22, 2020 Category: Orthopaedics Source Type: research

Editorial for Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)
Publication date: Available online 21 February 2020Source: Journal of Orthopaedic TranslationAuthor(s): Chelsea Hopkins, Harry K. Genant (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - February 21, 2020 Category: Orthopaedics Source Type: research

Exploratory meta-analysis on dose-related efficacy and complications of rhBMP-2 in anterior cervical discectomy and fusion: 1,539,021 cases from 2003 to 2017 studies
ConclusionsrhBMP-2 chosen in ACDF offered not only higher fusion, but also higher complication rate with more dysphagia and wound infections than non-rhBMP-2. To gain the efficacy and safety, rhBMP-2 dosing recommendations for ACDF would be better <0.7 mg/ level. Moreover, rhBMP-2 may be an option to improve nonunion in high risk of multi-level ACDF. (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - February 19, 2020 Category: Orthopaedics Source Type: research

3D printing-assisted percutaneous fixation makes the surgery for scaphoid nonunion more accurate and less invasive
Conclusions3-dimensional printing technique-assisted arthroscopic bone graft and fixation of scaphoid nonunion constitute an effective and accurate clinical treatment option. (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - February 18, 2020 Category: Orthopaedics Source Type: research

Biomechanical comparison of four tibial fixation techniques for meniscal root sutures in posterior medial meniscus root repair: A porcine study
This study investigated the fixation stability of four different tibial fixations for the meniscal root sutures. Twenty-four porcine tibiae with intact medial meniscus roots were randomly assigned into four groups: transosseous suture, washer, suture anchor or screw with washer. Each sample underwent cyclic loading followed by a load-to-failure test. The maximum average load and displacement at failure for each of the repair groups were as follows: transosseous suture, 232.8 ​N and 12.16 ​mm; washer, 189.9 ​N and 21.5 ​mm; suture anchor, 140.6 ​N and 13.8 ​mm and screw with washer, 167.9 ​N and 18.9 â...
Source: Journal of Orthopaedic Translation - February 18, 2020 Category: Orthopaedics Source Type: research

Poly(ethylene glycol)-sheddable reduction-sensitive polyurethane micelles for triggered intracellular drug delivery for osteosarcoma treatment
ConclusionFindings from this study suggest that the SS-PU-SS-PEG micelles could achieve well-controlled triggered drug release in a reduction environment and could therefore improve the antitumor efficacy of osteosarcoma therapies.Translation potential of this articleIn this study we developed PEG-sheddable reduction-sensitive polyurethane micelles (SS-PU-SS-PEG), which were able to achieve well-controlled triggered release of anti-tumor drug Doxorubicin (DOX) in an intracellular reduction environment. DOX-loaded SS-PU-SS-PEG micelles markedly improved the antitumor efficacy in a Saos-2 cells-bearing xenograft tumor model....
Source: Journal of Orthopaedic Translation - February 18, 2020 Category: Orthopaedics Source Type: research