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Exploring the correlation between COVID 19 and periodontal disease
This article explores the various hypotheses that link the two conditions, to understand their interrelationship. Targeted research may help elucidate evidence for screening of high-risk groups and identification of therapeutic targets. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Fatema Sayeed Keya Sircar Source Type: research

Role of Nidogen-2 in diagnosis and prognosis of head and neck squamous cell carcinoma: A systematic review
Conclusion: Data from the reviewed studies indicate that hypermethylation of NID-2 is highly specific for HNSCC. The high specificity is maintained in salivary and serum samples, facilitating accurate and non-invasive prognostication of HNSCC. The relatively lower sensitivity of NID-2 methylation may be overcome by analysing it along with a panel of multiple biomarkers such as HOX-A2 and YKL20. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Tabita Joy Chettiankandy Sanpreet S Sachdev Shubhangi P Khandekar Alka Dive Deepak Nagpal Jagdish V Tupkari Source Type: research

Evaluation of p16 expression in oral and oropharyngeal squamous cell carcinoma
Conclusion: p16 is an inexpensive, easily available marker, it may be incorporated routinely in all histologically diagnosed cases of OSCC and OPSCC. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Pallavi Saxena Sruthi Prasad Source Type: research

Centromere Protein F (CENPF): A novel marker for salivary gland pathology
Conclusion: Findings of the study suggest that CENPF can be regarded as a new cell proliferation marker for malignant salivary gland tumours. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: TA Lakshmi Malathi Narasimhan Thamizhchelvan Harikrishnan Sharadha T Rajan Source Type: research

Diagnostic yield of calcofluor white in the identification of Candida albicans in oral squamous cell carcinoma
Conclusion: Our results show minimal agreement with PAS with a Kappa score of 0.148 (95% CI = 0.39 to 0.09). Overall detection rate was similar for both the index test and reference standard although there was considerable number of intermediate test results. Sensitivity of CFW was comparable to that of earlier studies but specificity was low and the degree of concordance was 60.4%. Although CFW staining can come with high false positive they are a useful test for ruling out candida infection when the test result is negative. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Alagesan Chinnasamy Karthikeyan Ramalingam Sushruth Nayak Vikranth Rai Vidhya Gopinath Gurveen Chawla Source Type: research

Assessment of epidermal growth factor receptor in histological, clinical and pathological staging of oral squamous cell carcinoma
Conclusion: A preventive approach and assessment of EGFR in early stage of SCC provide better results. Subjects with higher EGFR value have poor prognosis and have to undergo postsurgical adjuvant therapy for long term-survival. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Priyanka Jagadish Umarani KB Rudresh T Smitha Prashanth Rajaram Source Type: research

Assessment of ergonomics to study the correlation between physical and psychological factors with prevalence of musculoskeletal disorders in practicing dentists
Conclusion: It is very important to increase the awareness of ergonomics and the influence of psychological stress in practicing dentists so that they can avoid these disorders and provide a high-quality treatment to their patients without any hindrance in their professional careers due to these disorders. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Ridima R Surve AK Anjali Treville Pereira Subraj Shetty Swati Shrikant Gotmare Christina Pereira Source Type: research

Microscopic appearances of commonly implanted food particles
Conclusion: It is important to study the microscopic appearances of commonly implanted food particles to prevent any diagnostic dilemmas. Further studies are required involving various other food particles and their microscopic appearances. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Reshma Poothakulath Krishnan Pratibha Ramani S Gheena Abilasha Ramasubramanian Monika Karunagaran R Hannah Source Type: research

Expression of MUC1, MUC2 and MUC5AC in salivary gland mucoepidermoid carcinoma: A case series with diagnostic implications
Conclusions: Although MUC1 is a reliable marker for all cell types of MEC but has no significant correlation with the tumour grade. MUC 2 has not been found to be a reliable diagnostic marker and has no significant correlation with the tumour grade. MUC 5AC has been found to have a significant expression in tumours with lymphoid infiltrate. There was no statistically significant correlation of MUC expression with the site, tumour grade and patient outcome. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Neelam Sood Swati Meena Priyanka Agarwala Source Type: research

Age estimation by Drusini & #39;s method and Jeon & #39;s method in Indian population & #8211; A comparative assessment
Conclusions: The study concludes that Jeon's method is more accurate than Drusini's in the Indian population. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Dharwadkar Pranjal Milind Manjushri Waingade Swapna Amod Patankar Amod Patankar Adwait Madhav Godse Prajakta Nagrale Source Type: research

Utility of serum homocysteine in oral squamous cell carcinoma patients as a potential biomarker
Conclusion: Serum Hcy levels could be utilized as a biological marker in the diagnosis and the prognosis of OSCC patients. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Sangeeta Palaskar Kalpana Joshi Rutuja Mukkanwar Rasika Pawar Gayatri Kulkarni Saurabhachandra Pawar Source Type: research

Anti-microbial efficacy of Vanilla planifolia leaf extract against common oral micro-biomes: A comparative study of two different antibiotic sensitivity tests
Conclusions: This experimental study presents a medicinal plant, an orchid Vanilla planifolia, which demonstrates the presence of essential anti-microbial agents in it, making it a potent, potential dental biomaterial with a positive and benefitting effect on the oral micro-environment. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Ajith K Kamath Iffat Nasim NP Muralidharan Ravalika N Kothuri Source Type: research

Immunohistochemical expression of paxillin in potentially malignant disorders and squamous cell carcinoma patients
Conclusion: Paxillin may play an important role in pathogenesis of oral squamous cell carcinoma by altering the adhesive properties of the tumor cells interacting with the extracellular matrix which in turn affects their invasive behavior and histologic differentiation. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Shakir Alam Madhusudan S Astekar Gaurav Sapra Ashutosh Agarwal Aditi Murari Agarwal Sowmya Gujjar Vishnu Rao Source Type: research

To analyse the mitotic and keratinisation correlation with bcl-2 expression in varying grades of oral epithelial dysplasia and squamous cell carcinoma
Conclusion: Sequential increase in the bcl-2 expression was observed in increasing grades of epithelial dysplasia, whereas bcl-2 expression was significantly decreased in ascending stages of squamous cell carcinoma thus, suggesting a possible role of bcl-2 in disease progression from premalignancy to malignancy. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Aparna Pathak Devi Charan Shetty Raghu Dhanapal Geetpriya Kaur Source Type: research

IHC expression of AKT in different grades of epithelial dysplasia: An in vitro study
Conclusion: An overall significant difference was observed when normal tissues were compared with epithelial dysplasia with a Chi-square value of 21.04, but there was no statistical significance between the three grades of epithelial dysplasias. In conclusion, this study suggests that Akt-1 overexpression can be one of the useful diagnostic markers for predicting the potential behaviour of oral dysplasias transforming into oral squamous cell carcinoma (OSCC). (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: A Sandhya Rani Manay Srinivas Munisekhar S Shylaja A Krishna Bhavani N Sangala E Sharath Kumar Reddy Source Type: research