Bilateral talon cusp in permanent maxillary lateral incisors: A case report, clinico-pathological review and proposal of an integrated classification
We describe the successful diagnosis and management of a rare case of nonsyndromic bilateral TC in permanent maxillary lateral incisors with conservative therapy. Further, while discussing the case, we present a brief clinicopathological review on TC and also propose an “integrated classification of talon cusp (ICTC) to describe the morphological aspects as well as indicate the severity and difficulty in the management of cases. An early specific diagnosis along with multidisciplinary treatment approach is recommended for TC, especially to avoid pulpal complications in teeth. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Vivek Mehta Aman Chowdhry Priyanka Kapoor Source Type: research

Oral microbiome research & #8211; A Beginner & #39;s glossary
Priya Nimish Deo, Revati Shailesh DeshmukhJournal of Oral and Maxillofacial Pathology 2022 26(1):87-92 Oral microbiome plays a key role in the etiology of oral diseases and is linked to many diseases in other parts of the body as well. This makes the oral microbiome an area of interest for researchers globally. A meticulous planning of the research project is the first and most crucial step while conducting an oral microbiome study. For beginners in this field, it is essential to be familiar with the terminologies used in oral microbiome research for a better understanding. The purpose of this article is to familiarize ne...
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Priya Nimish Deo Revati Shailesh Deshmukh Source Type: research

Membrane-organizing extension spike protein and its role as an emerging biomarker in oral squamous cell carcinoma
Sushma Bommanavar, Sujata R Kanetkar, Kailas D Datkhile, Ashwini L MoreJournal of Oral and Maxillofacial Pathology 2022 26(1):82-86 Oral squamous cell carcinoma (OSCC) is the most malignant tumor worldwide with a relatively poor prognosis. This can be due to lack of using new specific biomarkers as a mode of pristine interventional therapy for detecting the lesions at an early stage, thereby not allowing it to proceed to a severe advanced stage. Biomarkers, being the products of malignant cells, can prove to be promising prognostic factors in understanding the molecular pathogenesis of oral cancer. One such biomarker is m...
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Sushma Bommanavar Sujata R Kanetkar Kailas D Datkhile Ashwini L More Source Type: research

Comparison of blood parameters between periodontitis patients and healthy participants: A cross-sectional hematological study
Conclusion: Thus, within limitations, it can be concluded that increased levels of leukocytes, lymphocytes, RDW, MCV, platelet count and NLR depict the inflammatory state and destructive nature of periodontitis. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Hirak S Bhattacharya Rishabh Srivastava Shiva Shankar Gummaluri Manvi Chandra Agarwal Preeti Bhattacharya Madhusudan S Astekar Source Type: research

Evaluation and comparison of the efficacy of coconut oil as a clearing agent with xylene
Conclusion: It may be substituted for xylene without loss of information. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Bharadwaj Bordoloi Rohit Jaiswal Aanchal Tandon Amrita Jayaswal Abhinav Srivastava Nandita Gogoi Source Type: research

Evaluation of immunohistochemical expression of E-cadherin in pleomorphic adenoma and adenoid cystic carcinoma
Conclusion: E-cadherin proved to be a better marker for epithelial phenotypes in PAs. In ADCC difference in staining intensity between different histological subtypes suggests that further studies should be done to assess the usefulness of an immuno-marker to know the aggressive behavior of ADCC. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Bhavani Nagendra Sangala Vandana Raghunath Pratibha Kavle Anish Gupta Swati Shrikant Gotmare Venkata Subhash Andey Source Type: research

Orthokeratinized versus parakeratinized odontogenic keratocyst: Our institutional experience
Conclusion: The treatment and prognosis varies in both the variants of OKC, hence such epidemiological studies are helpful to ensure proper treatment for these distinct entities. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Jyoti Ravi Vijay Wadhwan Suhasini Palakshappa Gotur Source Type: research

Relationship between ABO blood group and Rh factor with oral potentially malignant disorder
Conclusion: Our study concludes that subjects with B+ blood group and habit of tobacco chewing and smoking are at higher risk to develop OPMDs than subjects with other blood groups. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: IP Mahalakshmi Pooja Sinha Tejavathi Nagaraj Durga Okade S Nonitha Bhavana T Veerabasaivaiah Source Type: research

Fine-needle aspiration cytology of salivary gland lesions
Conclusion: FNAC of the salivary gland is a safe, reliable and cost-effective technique which can be used as the first line of investigation in evaluating salivary gland lesions. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: A Rameeza M Hemalata Source Type: research

Immunohistochemical expression and evaluation of cyclin D1 and minichromosome maintenance 2 in oral squamous cell carcinoma and verrucous carcinoma
Conclusion: From the present study, we conclude that MCM2 has the potential to serve as a novel cell proliferation biomarker in OSCC and VC when compared to cyclin D1. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: TR Menaka S Shamala Ravikumar K Dhivya N Thilagavathi J Dinakaran Vinoth Kalaichelvan Source Type: research

Anti-plaque efficacy of Hi-Ora mouthrinse and 0.12 & #37; chlorhexidine gluconate in patients with chronic gingivitis: A case & #8211;control study
Conclusions: The results of the present study suggested Hi-Ora to be more effective than 0.12% CHX in reducing the mean GI and PI scores among all the 3 groups. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Melwin Mathew C Joyshree Velagapalli Jessie Ratan Votturu Kartheek S Thirumalai Mohan Nayak Banothu Source Type: research

Salivary metabolite signatures of oral cancer and leukoplakia through gas chromatography-mass spectrometry
Conclusion: The findings of the study suggest the application of salivary metabolomics as a promising tool in the identification of tumor-specific biomarkers in early diagnosis and prediction of OSCC and oral leukoplakia. In future, standardizing the protocol for salivary analysis and overcoming some of the limitations will be helpful to establish salivary metabolomics as a reliable, the highly sensitive and specific method for clinical use as an independent diagnostic aid. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Shoborose Tantray Seema Sharma Kanika Prabhat Nazima Nasrullah Manu Gupta Source Type: research

Evaluation of salivary oxidative stress in oral lichen planus using malonaldehyde
Conclusion: The higher level of MDA in patients with oral lichen planus suggests that free radicals and the resulting oxidative damage may be important in the pathogenesis of oral lichen planus lesions. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Shruti Singh Jaya Singh Basavaprabhu C Biradar Manjari Sonam Shaleen Chandra Fahad M Samadi Source Type: research

Role of nano curcumin on superoxide dismutase levels in leukoplakia
Conclusion: Nano curcumin is an excellent medical nutrition intervention derived from traditional natural products. The study has demonstrated the clinical efficacy of these new classes of therapeutic nutraceuticals such as nanocurcumin in treating oral leukoplakia, which are suitable for long-term use. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Sunanda Deb Deepak Bhargava Puja Bansal Vijay Kanuru Source Type: research

Coronavirus disease: Dental review
Saurabh Pratap Singh, Pratyush Singh, Om Prakash Gupta, Shalini GuptaJournal of Oral and Maxillofacial Pathology 2022 26(1):16-20 COVID-19 was declared a pandemic outbreak by the World Health Organization, creating a significant impact on health care system. Realizing the high risk associated with this disease and its high rate of transmission, dentists were instructed by health authorities, to stop providing treatment which includes aerosols and droplets and only except emergency complaints. This was mainly for protection of dental healthcare personnel, their families, contacts, and their patients from the transmission o...
Source: Journal of Oral and Maxillofacial Pathology - March 31, 2022 Category: ENT & OMF Authors: Saurabh Pratap Singh Pratyush Singh Om Prakash Gupta Shalini Gupta Source Type: research