Extra-cardiac uptake on technetium-99m pyrophosphate (Tc-99m PYP) scan: not just a matter of the heart
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 19, 2023 Category: Nuclear Medicine Source Type: research
Accurate and efficient rapid acquisition early post-injection stress-first CZT SPECT myocardial perfusion imaging with tetrofosmin and attenuation correction
ConclusionEarly post-injection stress-only imaging using CZT SPECT/CT appears promising with Tc-99m tetrofosmin with similar image quality, reader confidence, diagnosis, and need for a rest scan. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 18, 2023 Category: Nuclear Medicine Source Type: research
Machine learning to predict hemodynamically significant CAD based on traditional risk factors, coronary artery calcium and epicardial fat volume
AbstractWe sought to establish an explainable machine learning (ML) model to screen for hemodynamically significant coronary artery disease (CAD) based on traditional risk factors, coronary artery calcium (CAC) and epicardial fat volume (EFV) measured from non-contrast CT scans. 184 symptomatic inpatients who underwent Single Photon Emission Computed Tomography/Myocardial Perfusion Imaging (SPECT/MPI) and Invasive Coronary Angiography (ICA) were enrolled. Clinical and imaging features (CAC and EFV) were collected. Hemodynamically significant CAD was defined when coronary stenosis severity ≥ 50% with a matched reversible ...
Source: Journal of Nuclear Cardiology - July 11, 2023 Category: Nuclear Medicine Source Type: research
Prognostic value of myocardial flow reserve measured with CZT cardiac-dedicated SPECT low-dose dynamic myocardial perfusion imaging in patients with INOCA
ConclusionsMFR measured with low-dose D-MPI CZT SPECT provides incremental prognostic value in patients with INOCA. Patients with reduced MFR show an increased risk of MACE, increased symptom burdens, and impaired quality of life. INOCA patients with reduced MFR experienced higher rate of MACE than OCAD patients with normal MFR. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 11, 2023 Category: Nuclear Medicine Source Type: research
Machine learning to predict hemodynamically significant CAD based on traditional risk factors, coronary artery calcium and epicardial fat volume
AbstractWe sought to establish an explainable machine learning (ML) model to screen for hemodynamically significant coronary artery disease (CAD) based on traditional risk factors, coronary artery calcium (CAC) and epicardial fat volume (EFV) measured from non-contrast CT scans. 184 symptomatic inpatients who underwent Single Photon Emission Computed Tomography/Myocardial Perfusion Imaging (SPECT/MPI) and Invasive Coronary Angiography (ICA) were enrolled. Clinical and imaging features (CAC and EFV) were collected. Hemodynamically significant CAD was defined when coronary stenosis severity ≥ 50% with a matched reversible ...
Source: Journal of Nuclear Cardiology - July 11, 2023 Category: Nuclear Medicine Source Type: research
Prognostic value of myocardial flow reserve measured with CZT cardiac-dedicated SPECT low-dose dynamic myocardial perfusion imaging in patients with INOCA
ConclusionsMFR measured with low-dose D-MPI CZT SPECT provides incremental prognostic value in patients with INOCA. Patients with reduced MFR show an increased risk of MACE, increased symptom burdens, and impaired quality of life. INOCA patients with reduced MFR experienced higher rate of MACE than OCAD patients with normal MFR. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 11, 2023 Category: Nuclear Medicine Source Type: research
Prognosis and follow-up of patients with prosthetic valve endocarditis treated conservatively in relation to WBC-SPECT imaging
ConclusionsIn patients with PVE treated conservatively, intense WBC signal was associated with poor outcome. WBC-SPECT imaging appears as an interesting tool for risk stratification and to monitor locally the efficacy of antibiotic treatment. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 10, 2023 Category: Nuclear Medicine Source Type: research
Is dyspnea the new angina? The ever-changing profile of patients referred for CAD evaluation
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 10, 2023 Category: Nuclear Medicine Source Type: research
Prognosis and follow-up of patients with prosthetic valve endocarditis treated conservatively in relation to WBC-SPECT imaging
ConclusionsIn patients with PVE treated conservatively, intense WBC signal was associated with poor outcome. WBC-SPECT imaging appears as an interesting tool for risk stratification and to monitor locally the efficacy of antibiotic treatment. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 10, 2023 Category: Nuclear Medicine Source Type: research
Is dyspnea the new angina? The ever-changing profile of patients referred for CAD evaluation
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 10, 2023 Category: Nuclear Medicine Source Type: research
Decline in typical angina among patients referred for cardiac stress testing
ConclusionsThe prevalence of typical angina has declined to a very low level among contemporary patients referred for noninvasive cardiac tests. The angiographic findings among current typical angina patients are now quite heterogeneous, with one-third of such patients having normal coronary angiograms. However, typical angina remains associated with a substantially higher frequency of inducible myocardial ischemia compared to patients with other cardiac symptoms. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 6, 2023 Category: Nuclear Medicine Source Type: research
Coronary artery calcium score and pre-test probabilities as gatekeepers to predict and rule out perfusion defects in positron emission tomography
ConclusionsCACS and post-test probabilities are excellent predictors of abnormal perfusion and can rule it out with very high NPV in a substantial proportion of participants. CACS and post-test probabilities may be used as gatekeepers before advanced imaging.Graphical Summary: Prediction of Abnormal Perfusion in Position Emission Tomography Using Coronary Artery Calcium Score and Pre-Test ProbabilitiesCoronary artery calcium score (CACS) predicted abnormal perfusion (SSS ≥ 4) in myocardial positron emission tomography (PET) better than pre-test probabilities of coronary artery disease (CAD), while pre-test-AHA/ACC and p...
Source: Journal of Nuclear Cardiology - July 6, 2023 Category: Nuclear Medicine Source Type: research
Decline in typical angina among patients referred for cardiac stress testing
ConclusionsThe prevalence of typical angina has declined to a very low level among contemporary patients referred for noninvasive cardiac tests. The angiographic findings among current typical angina patients are now quite heterogeneous, with one-third of such patients having normal coronary angiograms. However, typical angina remains associated with a substantially higher frequency of inducible myocardial ischemia compared to patients with other cardiac symptoms. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 6, 2023 Category: Nuclear Medicine Source Type: research
Coronary artery calcium score and pre-test probabilities as gatekeepers to predict and rule out perfusion defects in positron emission tomography
ConclusionsCACS and post-test probabilities are excellent predictors of abnormal perfusion and can rule it out with very high NPV in a substantial proportion of participants. CACS and post-test probabilities may be used as gatekeepers before advanced imaging.Graphical Summary: Prediction of Abnormal Perfusion in Position Emission Tomography Using Coronary Artery Calcium Score and Pre-Test ProbabilitiesCoronary artery calcium score (CACS) predicted abnormal perfusion (SSS ≥ 4) in myocardial positron emission tomography (PET) better than pre-test probabilities of coronary artery disease (CAD), while pre-test-AHA/ACC and p...
Source: Journal of Nuclear Cardiology - July 6, 2023 Category: Nuclear Medicine Source Type: research
