Identification of a ceRNA Network Driven by Copy Number Variations in Esophageal Cancer
CONCLUSIONS: This study identified 11 CNV-driven lncRNAs that might affect EC development, 2 of which have promising effects if applied to drug treatment. These findings might assist in identifying novel treatments for EC.PMID:38246614 | DOI:10.1272/jnms.JNMS.2023_90-611 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Guoxi Xu Huaishuai Wang Yixiang Zhuang Qiyi Lin Yinlin Li Zhicong Cai Gaofeng Lin Weibo Liu Source Type: research
Opioid-Related Respiratory Depression in Non-Cancer Patients, as Reported in the Japanese Adverse Drug Event Report Database
CONCLUSIONS: Our findings suggest that elderly CNCP patients should be closely monitored after the start of opioid treatment, especially during the first week and, if possible, for 1 month, even if starting doses are within ranges recommended by the manufacturer and guidelines.PMID:38246615 | DOI:10.1272/jnms.JNMS.2023_90-612 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Hideki Sugawara Mayako Uchida Shinya Suzuki Yukio Suga Yoshihiro Uesawa Takayuki Nakagawa Hisamitsu Takase Source Type: research
Japanese Nationwide Comparative Survey of Medication Guidance Provided by Certified and Uncertified Palliative Care Pharmacists
CONCLUSION: As compared with uncertified pharmacists, certified pharmacists intervened more proactively and provided a broader range of palliative care.PMID:38246616 | DOI:10.1272/jnms.JNMS.2023_90-613 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Rei Tanaka Yumi Satoh Yukio Suga Junichi Nakagawa Masayuki Miyazaki Ryoichi Hagiwara Mayako Uchida Hisamitsu Takase Source Type: research
A Case of Paraneoplastic Neurological Syndrome Associated with Breast Cancer Detected while Searching for the Cause of Involuntary Movement
We report a case of PNS whose neurological symptoms followed a subacute course and were relieved after breast cancer treatment.PMID:38246617 | DOI:10.1272/jnms.JNMS.2023_90-608 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Ai Sato Yosuke Fujisawa Maki Nakai Tomoko Kurita Keiko Yanagihara Hiroyuki Takei Source Type: research
Active Tuberculosis in a Patient Receiving Adalimumab for Psoriatic Arthritis and Chemoprophylaxis for Latent Tuberculosis Infection
We report a rare case of active tuberculosis despite chemoprophylaxis for LTBI in a patient receiving adalimumab for PsA. A 60-year-old Japanese woman who had received a diagnosis of psoriasis at age 35 years presented with arthralgia of the right hand, which she first noticed 2 months previously. Physical examination showed scattered erythematous papules and plaques with scales on her trunk, extremities, and scalp. Her right metacarpophalangeal and proximal interphalangeal joints were swollen and painful, and her right wrist and elbow were painful. PsA was diagnosed and adalimumab was initiated. Because an interferon-γ r...
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Shun Miyazaki Kazue Fujita Saeko Ozaki Susumu Ichiyama Michiko Ito Toshihiko Hoashi Naoko Kanda Hidehisa Saeki Source Type: research
Identification of a ceRNA Network Driven by Copy Number Variations in Esophageal Cancer
CONCLUSIONS: This study identified 11 CNV-driven lncRNAs that might affect EC development, 2 of which have promising effects if applied to drug treatment. These findings might assist in identifying novel treatments for EC.PMID:38246614 | DOI:10.1272/jnms.JNMS.2023_90-611 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Guoxi Xu Huaishuai Wang Yixiang Zhuang Qiyi Lin Yinlin Li Zhicong Cai Gaofeng Lin Weibo Liu Source Type: research
Opioid-Related Respiratory Depression in Non-Cancer Patients, as Reported in the Japanese Adverse Drug Event Report Database
CONCLUSIONS: Our findings suggest that elderly CNCP patients should be closely monitored after the start of opioid treatment, especially during the first week and, if possible, for 1 month, even if starting doses are within ranges recommended by the manufacturer and guidelines.PMID:38246615 | DOI:10.1272/jnms.JNMS.2023_90-612 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Hideki Sugawara Mayako Uchida Shinya Suzuki Yukio Suga Yoshihiro Uesawa Takayuki Nakagawa Hisamitsu Takase Source Type: research
Japanese Nationwide Comparative Survey of Medication Guidance Provided by Certified and Uncertified Palliative Care Pharmacists
CONCLUSION: As compared with uncertified pharmacists, certified pharmacists intervened more proactively and provided a broader range of palliative care.PMID:38246616 | DOI:10.1272/jnms.JNMS.2023_90-613 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Rei Tanaka Yumi Satoh Yukio Suga Junichi Nakagawa Masayuki Miyazaki Ryoichi Hagiwara Mayako Uchida Hisamitsu Takase Source Type: research
A Case of Paraneoplastic Neurological Syndrome Associated with Breast Cancer Detected while Searching for the Cause of Involuntary Movement
We report a case of PNS whose neurological symptoms followed a subacute course and were relieved after breast cancer treatment.PMID:38246617 | DOI:10.1272/jnms.JNMS.2023_90-608 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Ai Sato Yosuke Fujisawa Maki Nakai Tomoko Kurita Keiko Yanagihara Hiroyuki Takei Source Type: research
Active Tuberculosis in a Patient Receiving Adalimumab for Psoriatic Arthritis and Chemoprophylaxis for Latent Tuberculosis Infection
We report a rare case of active tuberculosis despite chemoprophylaxis for LTBI in a patient receiving adalimumab for PsA. A 60-year-old Japanese woman who had received a diagnosis of psoriasis at age 35 years presented with arthralgia of the right hand, which she first noticed 2 months previously. Physical examination showed scattered erythematous papules and plaques with scales on her trunk, extremities, and scalp. Her right metacarpophalangeal and proximal interphalangeal joints were swollen and painful, and her right wrist and elbow were painful. PsA was diagnosed and adalimumab was initiated. Because an interferon-γ r...
Source: Journal of Nippon Medical School - January 21, 2024 Category: Universities & Medical Training Authors: Shun Miyazaki Kazue Fujita Saeko Ozaki Susumu Ichiyama Michiko Ito Toshihiko Hoashi Naoko Kanda Hidehisa Saeki Source Type: research
Human adipose tissue-derived stem cells inhibit coronary artery vasculitis in a mouse model of Kawasaki disease
CONCLUSIONS: The present experimental results indicate that hADSCs have an early anti-inflammatory effect, and that Gal-1 may be involved in preventing inflammation and reducing tissue damage.PMID:38233123 | DOI:10.1272/jnms.JNMS.2024_91-212 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 17, 2024 Category: Universities & Medical Training Authors: Ryohei Fukunaga Takahiro Ueda Ryosuke Matsui Toshikazu Itabashi Ryuji Fukazawa Noriko Nagi-Miura Yasuhiko Itoh Source Type: research
Clinicopathological characteristics of everolimus-associated interstitial lung disease: A single-center consecutive analysis
CONCLUSIONS: Everolimus-associated ILD is mild and has a favorable prognosis. Patients with symptomatic ILD were more likely to have higher SP-D levels than those with asymptomatic ILD. Granulomatous lesions are an important pathological feature of everolimus-associated ILD.PMID:38233124 | DOI:10.1272/jnms.JNMS.2024_91-211 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 17, 2024 Category: Universities & Medical Training Authors: Yoshinobu Saito Yasuhiro Terasaki Takeru Kashiwada Toru Tanaka Hiroyuki Takei Go Kimura Yukihiro Kondo Tetsuro Kawagoe Akira Matsushita Rintaro Noro Yuji Minegishi Koichiro Kamio Masahiro Seike Akihiko Gemma Source Type: research
Changes in metamorphopsia in patients undergoing treatment for vitreoretinal disorders
CONCLUSION: This quantitative study indicated that metamorphopsia is present in most patients undergoing surgery for vitreoretinal diseases and is most severe in ERM. In these patients, vitrectomy improved visual acuity but not metamorphopsia.PMID:38233125 | DOI:10.1272/jnms.JNMS.2024_91-114 (Source: Journal of Nippon Medical School)
Source: Journal of Nippon Medical School - January 17, 2024 Category: Universities & Medical Training Authors: Fumiki Okamoto Source Type: research
Smoking-related interstitial fibrosis and Smoker's macrophages
J Nippon Med Sch. 2024 Jan 16. doi: 10.1272/jnms.JNMS.2024_91-113. Online ahead of print.ABSTRACTSmoking-related interstitial lung diseases (SRILDs) are a group of heterogeneous diffuse pulmonary parenchymal diseases associated with tobacco exposure. Smoking-related interstitial fibrosis (SRIF) is relatively recent, a pathologically defined form of SRILDs. SRIF is characterized by the accumulation of macrophages in the alveolar spaces, which is associated with interstitial inflammation and fibrosis. The macrophages frequently contain light brown pigment and are called 'smoker' s macrophages'. Patients with SRIF who have cl...
Source: Journal of Nippon Medical School - January 17, 2024 Category: Universities & Medical Training Authors: Namiko Taniuchi Yoshinobu Saito Norio Motoda Masahiro Seike Source Type: research
Current status of robotic hepatobiliary and pancreatic surgery
J Nippon Med Sch. 2024 Jan 16. doi: 10.1272/jnms.JNMS.2024_91-109. Online ahead of print.ABSTRACTLaparoscopic surgery is performed worldwide and has clear economic and social benefits in terms of patient recovery time. It is used for most gastrointestinal surgical procedures, but laparoscopic surgery for more complex procedures in the esophageal, hepatobiliary, and pancreatic regions remains challenging. Minimally invasive surgery that results in accurate tumor dissection is vital in surgical oncology, and development of surgical systems and instruments plays a key role in assisting surgeons to achieve this. A notable adva...
Source: Journal of Nippon Medical School - January 17, 2024 Category: Universities & Medical Training Authors: Keisuke Minamimura Yuto Aoki Youhei Kaneya Satoshi Matsumoto Hiroki Arai Daisuke Kakinuma Yukio Oshiro Yoichi Kawano Masanori Watanabe Yoshiharu Nakamura Hideyuki Suzuki Hiroshi Yoshida Source Type: research
