The Impact of Prehospital Intubation With and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less
This study evaluates the impact on outcome of prehospital intubation with and without sedation in trauma patients with a GCS of ≤8. Methods: A retrospective cohort analysis of severely injured trauma patients registered in the TraumaRegister DGU of the German Trauma Society (DGU) from 2002 to 2013 was conducted. Only directly admitted patients alive on admission and with a GCS of ≤8 at the scene were included. The observed outcome was matched with the expected outcome deriving from the Revised Injury Severity Classification, version II (RISC-II). Furthermore, a Standardized Mortality Ratio (SMR) was calculated for v...
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery
Conclusions: The combination of low-dose tramadol (1 mg/kg) and paracetamol has comparable analgesia and a decreased incidence of nausea and vomiting compared with the higher dose of tramadol (1.5 mg/kg) and paracetamol combination. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

A Randomized Controlled Trial Studying the Role of Dexamethasone in Scalp Nerve Blocks for Supratentorial Craniotomy
Conclusions: Addition of dexamethasone as an adjuvant to local anesthetics in scalp nerve blocks in the setting of perioperative steroid therapy does not appear to provide any additional benefit with respect to prolongation of the duration of the block. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Acute Kidney Injury After Subarachnoid Hemorrhage
Background: Acute kidney injury (AKI) is common in critically ill patients and may contribute to poor outcome. Few data are available on the incidence and impact of AKI in patients suffering from nontraumatic subarachnoid hemorrhage (SAH). Methods: We reviewed all patients admitted to our Department of Intensive Care with SAH over a 3-year period. Exclusion criteria were time from SAH symptoms to intensive care unit (ICU) admission>96 hours and ICU stay (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Use of Dexmedetomidine for Prophylactic Analgesia and Sedation in Patients With Delayed Extubation After Craniotomy: A Randomized Controlled Trial
Conclusions: Dexmedetomidine may be an effective prophylactic agent to induce sedation and analgesia in patients with delayed extubation after craniotomy. The use of dexmedetomidine (0.6 μg/kg/h) infusion does not produce respiratory depression, but may increase the incidence of bradycardia. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Neuroanesthesiology Update
We reviewed manuscripts published in 2016 that are related to the care of neurosurgical patients or the perioperative care of patients with neurological diseases. We address the broad categories of general neurosurgery and neuroanesthesiology, anesthetic neurotoxicity and neuroprotection, stroke, traumatic brain injury, and nervous system monitoring. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - March 11, 2017 Category: Anesthesiology Tags: Review Article Source Type: research

Abstracts From the Neuro Anaesthetic and Critical Care Society of Great Britain and Ireland's Annual Scientific Meeting-Southampton, May 19 to 20, 2016.
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Abstract: PDF Only Source Type: research

Handbook of Bleeding and Coagulation in Neurosurgery
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Book Reviews Source Type: research

Surgical Management of Pain
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Book Reviews Source Type: research

JNA Journal Club
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Journal Club Source Type: research

The Power of Raw Data
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Regional Anesthesia to the Scalp for Craniotomy: Innovation With Innervation
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Regional Anesthesia for Craniotomy
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Intubation Difficulty Scale Score and Videolaryngoscopes
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparing the Intubation Performance of Macintosh and Airtraq Laryngoscopes
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Extradural Hematoma With Unanticipated Difficult Intubation Due to Rhinoscleromatosis
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The Effect of Increased Intracranial Pressure on Pulmonary Compliance in a Neonate
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Visualizing Impending Cerebral Circulatory Arrest Caused by Intracranial Hypertension Following Aneurysmal Subarachnoid Hemorrhage
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Acute Subdural Hematoma Causing Neurogenic Pulmonary Edema Following Lumbar Spine Surgery
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Mirror Image Acute Subdural Hematoma Complicating Preexisting Bilateral Chronic Subdural Hematoma After Spinal Anesthesia
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Hyperventilation, Sympathetic and Metabolic Derangements After Endoscopic Third Ventriculostomy
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

ILMA as an Alternative to Face Mask Ventilation in a Case of Nasal Chondrosarcoma
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The Effects of Handed Bias of Physicians and the Laterality of Recumbent Position of Patients on the Success Rate of Lumbar Puncture
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients
Conclusions: Dexamethasone exposure induces a genetic program and CEBPB expression in GSCs that adversely affects key cellular functions and response to therapeutics. High risk scores associated with these genes have negative prognostic value in patients. Our findings further suggest camptothecin as a potential neutralizer of adverse dexamethasone-mediated effects. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Laboratory Investigations Source Type: research

Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats
Conclusions: Sevoflurane postconditioning reduced apoptosis by increasing P-JAK and P-STAT expression after transient global ischemia in rats, and AG490 reversed the beneficial antiapoptotic effects of sevoflurane postconditioning, suggesting that the JAK-STAT pathway may be involved in the antiapoptotic mechanism of sevoflurane postconditioning. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Laboratory Investigations Source Type: research

Intraoperative Monitoring of Diaphragm Neural Pathways During Cervical Surgery by Electrical Stimulation and Recordings of Ventilator Waveforms: Physiological Bases and Pilot Study
Conclusion: Intraoperative monitoring of the diaphragmatic responses to stimulation can be advocated in surgery at the cervical spine level, and also more widely in surgery in the supraclavicular region, when neural structures responsible for diaphragmatic function are at risk. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Report Source Type: research

Association Between Perioperative Hyperglycemia and Survival in Patients With Glioblastoma
Conclusions: Preoperative hyperglycemia is associated with poor OS after GBM surgery. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Comparison of Intra-Abdominal Pressure Among 3 Prone Positional Apparatuses After Changing From the Supine to the Prone Position and Applying Positive End-Expiratory Pressure in Healthy Euvolemic Patients: A Prospective Observational Study
In this study, we compared the IAP after changing to the prone position and applying various positive end-expiratory pressure (PEEP) levels among 3 prone positional apparatuses. Methods: A total of 108 healthy euvolemic patients undergoing elective prone spinal surgery were divided into 3 groups based on the positional apparatus used: the Jackson spinal table was used in group J (n=36), the Wilson frame in group W (n=36), and chest rolls in group C (n=36). The IAP was measured 2 minutes after application of 0, 3, 6, and 9 cm H2O of PEEP. Results: The IAP in the supine position was 6.4±3.0, 5.9±2.8, and 7.1&...
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Equiosmolar Solutions of Hypertonic Saline and Mannitol Do Not Impair Blood Coagulation During Elective Intracranial Surgery
Conclusions: The use of 5 mL/kg of equiosmolar solutions of 3% HS and 20% mannitol applied to reach a brain relaxation during elective craniotomy does not induce coagulation impairment as evidenced by ROTEM and standard coagulation tests. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Comparison of Continuous Noninvasive Blood Pressure Monitoring by TL-300 With Standard Invasive Blood Pressure Measurement in Patients Undergoing Elective Neurosurgery
Conclusions: TL-300 system is a promising noninvasive alternative to the invasive arterial catheter method for intraoperative BP monitoring, with a high accuracy and precision. With the limitation of the current retrospective study, further prospective method comparison studies are needed. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Abstracts from the 44th Annual Meeting of the Society for Neuroscience in Anesthesiology and Critical Care, Chicago, IL, October 20-21, 2016.
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Abstracts: PDF Only Source Type: research

Congenital Dysfibrinogenemia, An Unusual Cause for Subdural Hematoma in an Infant
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Supplementary Motor Area (SMA) Syndrome: An Enigma to Anesthesiologists!
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Meta-areas of the Trigeminocardiac Reflex Within the Skull Base: A Neuroanatomic “Thinking” Model
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Anesthetic Management of a Case of Posterior Fossa Tumor With An Intracardiac Mass
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Traumatic Carotid-Cavernous Fistula and Anesthetic Challenges
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Oxygen Desaturation During Drainage of Brain Abscess in Prone Position in a Child With Eisenmenger Syndrome
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Acute Epidural Hematoma Following Acute Subdural Hematoma Evacuation in a Child With Glanzmann Thrombasthenia
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Venous Air Embolism During Brain Abscess Surgery
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Brainstem Contusion: A Fallacy of GCS-BIS Synchrony
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Inadvertent Neuraxial Anesthesia in a Patient With an Intracranial Space-occupying Lesion
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Anesthetic Management of an Unusual Case of Coats’ Disease Complex: Use of Dexmedetomidine
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Journal Club
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Journal Club Source Type: research

Analysis of MRI Utilization in Pediatric Patients
Introduction: Although animal studies have consistently demonstrated long-term neurocognitive deficits following early anesthetic exposure under certain conditions, risk in human children remains unknown. Magnetic resonance imaging (MRI) in young patients often requires anesthesia to facilitate image acquisition. We studied MRI utilization in a pediatric population, and associated use of anesthesia for ambulatory MRI. Materials and Methods: Data were obtained from the New York State Inpatient Database and State Ambulatory Surgery and Services Database on MRI performed in children under the age of 18 years from 2005 to 201...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons
Conclusions: Sevoflurane interferes with growth cone motility, which is a critical process in brain circuitry formation. Our data suggest that this may occur through an action on the p75NTR, which promotes growth inhibitory signaling by the Rho pathway. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Use of Anesthesia for Imaging Studies and Interventional Procedures in Children
Ongoing investigation from the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) study hopes to examine the long-term effect on cognitive and language development of a single anesthetic exposure in children undergoing inguinal hernia repair. The fifth PANDA Symposium, held in April 2016, continued the mission of previous symposia to examine evidence from basic science and clinical studies on potential neurotoxic effects of anesthetics on developing brain. At the 2016 Symposium, a panel of specialists from nonsurgical pediatric disciplines including anesthesiology, radiology, neurology, gastroenterology, oncology, ca...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Optimal Timing of Surgical Procedures in Pediatric Patients
The Pediatric Anesthesia Neuro Development Assessment (PANDA) team at the Anesthesiology Department at Columbia University Medical Center held its fifth biennial symposium to discuss issues regarding potential neurotoxicity of anesthetic agents in pediatric patients. Overall optimal surgical timing as well as a "critical window" for surgery on a specialty specific basis are areas of focus for the American Academy of Pediatrics Surgical Advisory Panel. An ad hoc panel of pediatric surgical experts representing general surgery, urology, neurosurgery, and ophthalmology was assembled for this meeting and provided a d...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research