Log in to search using one of your social media accounts:

 

Regional Anesthesia to the Scalp for Craniotomy: Innovation With Innervation
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Regional Anesthesia for Craniotomy
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Intubation Difficulty Scale Score and Videolaryngoscopes
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparing the Intubation Performance of Macintosh and Airtraq Laryngoscopes
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Extradural Hematoma With Unanticipated Difficult Intubation Due to Rhinoscleromatosis
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The Effect of Increased Intracranial Pressure on Pulmonary Compliance in a Neonate
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Visualizing Impending Cerebral Circulatory Arrest Caused by Intracranial Hypertension Following Aneurysmal Subarachnoid Hemorrhage
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Acute Subdural Hematoma Causing Neurogenic Pulmonary Edema Following Lumbar Spine Surgery
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Mirror Image Acute Subdural Hematoma Complicating Preexisting Bilateral Chronic Subdural Hematoma After Spinal Anesthesia
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Hyperventilation, Sympathetic and Metabolic Derangements After Endoscopic Third Ventriculostomy
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

ILMA as an Alternative to Face Mask Ventilation in a Case of Nasal Chondrosarcoma
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The Effects of Handed Bias of Physicians and the Laterality of Recumbent Position of Patients on the Success Rate of Lumbar Puncture
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients
Conclusions: Dexamethasone exposure induces a genetic program and CEBPB expression in GSCs that adversely affects key cellular functions and response to therapeutics. High risk scores associated with these genes have negative prognostic value in patients. Our findings further suggest camptothecin as a potential neutralizer of adverse dexamethasone-mediated effects. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Laboratory Investigations Source Type: research

Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats
Conclusions: Sevoflurane postconditioning reduced apoptosis by increasing P-JAK and P-STAT expression after transient global ischemia in rats, and AG490 reversed the beneficial antiapoptotic effects of sevoflurane postconditioning, suggesting that the JAK-STAT pathway may be involved in the antiapoptotic mechanism of sevoflurane postconditioning. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Laboratory Investigations Source Type: research

Intraoperative Monitoring of Diaphragm Neural Pathways During Cervical Surgery by Electrical Stimulation and Recordings of Ventilator Waveforms: Physiological Bases and Pilot Study
Conclusion: Intraoperative monitoring of the diaphragmatic responses to stimulation can be advocated in surgery at the cervical spine level, and also more widely in surgery in the supraclavicular region, when neural structures responsible for diaphragmatic function are at risk. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Report Source Type: research

Association Between Perioperative Hyperglycemia and Survival in Patients With Glioblastoma
Conclusions: Preoperative hyperglycemia is associated with poor OS after GBM surgery. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Comparison of Intra-Abdominal Pressure Among 3 Prone Positional Apparatuses After Changing From the Supine to the Prone Position and Applying Positive End-Expiratory Pressure in Healthy Euvolemic Patients: A Prospective Observational Study
In this study, we compared the IAP after changing to the prone position and applying various positive end-expiratory pressure (PEEP) levels among 3 prone positional apparatuses. Methods: A total of 108 healthy euvolemic patients undergoing elective prone spinal surgery were divided into 3 groups based on the positional apparatus used: the Jackson spinal table was used in group J (n=36), the Wilson frame in group W (n=36), and chest rolls in group C (n=36). The IAP was measured 2 minutes after application of 0, 3, 6, and 9 cm H2O of PEEP. Results: The IAP in the supine position was 6.4±3.0, 5.9±2.8, and 7.1&...
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Equiosmolar Solutions of Hypertonic Saline and Mannitol Do Not Impair Blood Coagulation During Elective Intracranial Surgery
Conclusions: The use of 5 mL/kg of equiosmolar solutions of 3% HS and 20% mannitol applied to reach a brain relaxation during elective craniotomy does not induce coagulation impairment as evidenced by ROTEM and standard coagulation tests. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Comparison of Continuous Noninvasive Blood Pressure Monitoring by TL-300 With Standard Invasive Blood Pressure Measurement in Patients Undergoing Elective Neurosurgery
Conclusions: TL-300 system is a promising noninvasive alternative to the invasive arterial catheter method for intraoperative BP monitoring, with a high accuracy and precision. With the limitation of the current retrospective study, further prospective method comparison studies are needed. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - December 9, 2016 Category: Anesthesiology Tags: Clinical Investigations Source Type: research

Abstracts from the 44th Annual Meeting of the Society for Neuroscience in Anesthesiology and Critical Care, Chicago, IL, October 20-21, 2016.
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Abstracts: PDF Only Source Type: research

Congenital Dysfibrinogenemia, An Unusual Cause for Subdural Hematoma in an Infant
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Supplementary Motor Area (SMA) Syndrome: An Enigma to Anesthesiologists!
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Meta-areas of the Trigeminocardiac Reflex Within the Skull Base: A Neuroanatomic “Thinking” Model
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Anesthetic Management of a Case of Posterior Fossa Tumor With An Intracardiac Mass
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Traumatic Carotid-Cavernous Fistula and Anesthetic Challenges
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Oxygen Desaturation During Drainage of Brain Abscess in Prone Position in a Child With Eisenmenger Syndrome
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Acute Epidural Hematoma Following Acute Subdural Hematoma Evacuation in a Child With Glanzmann Thrombasthenia
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Venous Air Embolism During Brain Abscess Surgery
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Brainstem Contusion: A Fallacy of GCS-BIS Synchrony
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Inadvertent Neuraxial Anesthesia in a Patient With an Intracranial Space-occupying Lesion
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Anesthetic Management of an Unusual Case of Coats’ Disease Complex: Use of Dexmedetomidine
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Correspondence Source Type: research

Journal Club
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Journal Club Source Type: research

Analysis of MRI Utilization in Pediatric Patients
Introduction: Although animal studies have consistently demonstrated long-term neurocognitive deficits following early anesthetic exposure under certain conditions, risk in human children remains unknown. Magnetic resonance imaging (MRI) in young patients often requires anesthesia to facilitate image acquisition. We studied MRI utilization in a pediatric population, and associated use of anesthesia for ambulatory MRI. Materials and Methods: Data were obtained from the New York State Inpatient Database and State Ambulatory Surgery and Services Database on MRI performed in children under the age of 18 years from 2005 to 201...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons
Conclusions: Sevoflurane interferes with growth cone motility, which is a critical process in brain circuitry formation. Our data suggest that this may occur through an action on the p75NTR, which promotes growth inhibitory signaling by the Rho pathway. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Use of Anesthesia for Imaging Studies and Interventional Procedures in Children
Ongoing investigation from the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) study hopes to examine the long-term effect on cognitive and language development of a single anesthetic exposure in children undergoing inguinal hernia repair. The fifth PANDA Symposium, held in April 2016, continued the mission of previous symposia to examine evidence from basic science and clinical studies on potential neurotoxic effects of anesthetics on developing brain. At the 2016 Symposium, a panel of specialists from nonsurgical pediatric disciplines including anesthesiology, radiology, neurology, gastroenterology, oncology, ca...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Optimal Timing of Surgical Procedures in Pediatric Patients
The Pediatric Anesthesia Neuro Development Assessment (PANDA) team at the Anesthesiology Department at Columbia University Medical Center held its fifth biennial symposium to discuss issues regarding potential neurotoxicity of anesthetic agents in pediatric patients. Overall optimal surgical timing as well as a "critical window" for surgery on a specialty specific basis are areas of focus for the American Academy of Pediatrics Surgical Advisory Panel. An ad hoc panel of pediatric surgical experts representing general surgery, urology, neurosurgery, and ophthalmology was assembled for this meeting and provided a d...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Lessons Learned: Studying the Vulnerable Brain
Neurotoxicity related to early exposure to various insults, both anesthesia-related and nonanesthesia-related, is a topic of ongoing and increasing interest. To better understand the process by which this might occur, the fifth PANDA Symposium convened a session in which 4 notable neuroscientists discussed current concepts and research in neurodevelopment, highlighting periods of particular susceptibility and ways in which neural connectivity and systemic functioning may be affected. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Mechanisms for Research Support
During the second day of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) symposium 2016, 3 invited speakers focused on future directions for the PANDA group. This session, entitled "The Way Forward," included 3 talks on how other groups have organized through public-private partnerships (ACTTION), obtained NIH funding, and how to better communicate a research message. Dr Robert H. Dworkin spoke on the mission of the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities and Networks (ACTTION), which is a public-private partnership with the United States Food and ...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Biomarkers, Genetics, and Epigenetic Studies to Explore the Neurocognitive Effects of Anesthesia in Children
Exposure to commonly used anesthetic agents causes widespread neuronal degeneration in the developing mammalian brain and has been shown to impair neurodevelopment in a variety of newborn vertebrate animal species. Although retrospective studies have suggested an association between anesthesia exposure in childhood and subsequent neurodevelopmental abnormalities, a causal relationship in humans has yet to be demonstrated. Unfortunately, translation of findings from bench to bedside is limited by several factors and histologic assessment in healthy children following exposure to anesthesia is not possible. Therefore, to pro...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

What Next After GAS and PANDA?
On April 16 and 17, 2016, the Fifth biennial Pediatric Anesthesia & Neurodevelopment Assessment (PANDA) symposium was convened at the Morgan Stanley Children's Hospital of New York at Columbia University Medical Center. During the symposium, experts in the fields of anesthesiology, neuropsychology, and epidemiology were convened in a small group session to determine the level of confidence in the current clinical evidence and the next steps in anesthetic neurotoxicity clinical research. Among the participants in the discussion, there remained a lack of consensus on whether anesthetic exposure causes long-term neurodeve...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Physical Activity and Cognitive Development: A Meta-Analysis
Conclusions and Implications: Increased regular physical activity is associated with a small and measurable, improvement in neuropsychological tests of executive functions, specifically inhibitory control. Executive functions play an important role in complex behavior, and may contribute to academic and career achievement as well as success in social interaction. This finding provides support for the important interaction between exercise and cognitive functioning. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature
Data from epidemiologic studies and animal models have raised a concern that exposure to anesthetic agents during early postnatal life may cause lasting impairments in cognitive function. It is hypothesized that this is due to disruptions in brain development, but the mechanism underlying this toxic effect remains unknown. Ongoing research, particularly in rodents, has begun to address this question. In this review we examine currently postulated molecular mechanisms of anesthetic toxicity in the developing brain, including effects on cell death pathways, growth factor signaling systems, NMDA and GABA receptors, mitochondr...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Summary of the Update Session on Clinical Neurotoxicity Studies
This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Report on the Fifth PANDA Symposium on “Anesthesia and Neurodevelopment in Children”
On April 16 and 17, 2016, the Pediatric Anesthesia and Neurodevelopment Assessment (PANDA) study held its fifth biennial symposium at the Morgan Stanley Children's Hospital of New York. The PANDA symposium has served as a key forum for clinicians, researchers, and other major stakeholders to gather and review the current state of preclinical and clinical research related to anesthetic neurotoxicity in children. Goals of the meeting included assessing how current knowledge has translated and impacted clinical care of patients who may be at risk, and future directions for research and policy. The program participants represe...
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Introduction to the Proceedings of the Fifth PANDA Symposium on “Anesthesia and Neurodevelopment in Children”
No abstract available (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Departments: Supplement: Proceedings of the Fifth PANDA Symposium on Anesthesia and Neurodevelopment in Children Source Type: research

Intracarotid Etomidate Decreases the Interhemispheric Synchronization in Electroencephalogram (EEG) During the Wada Test
Conclusions: Our study showed that the EEG effects of intracarotid ipsilateral injection of etomidate is not uniform in both hemispheres. Decrease in the interhemispheric synchronization of delta waves might serve as an indicator of ipsilateral effect of etomidate on the brain. Additional studies are needed to confirm our findings. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Clinical Reports Source Type: research

The Effect of Clevidipine on Cerebral Blood Flow Velocity and Carbon Dioxide Reactivity in Human Volunteers
Conclusions: Clevidipine infusion did not significantly increase CBFV nor was cerebral CO2 reactivity reduced during maximal-dose clevidipine infusion. Further systematic investigation of clevidipine in patients with central nervous system pathology seems justified. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Clinical Reports Source Type: research

Noninvasive Measurement of Cerebral Blood Flow Under Anesthesia Using Arterial Spin Labeling MRI: A Pilot Study
Conclusions: ASL-MRI is a feasible, noninvasive method of quantitative estimation of global and regional CBF in mechanically ventilated patients under anesthesia. In this pilot study CBF was consistently greater with sevoflurane than with propofol. (Source: Journal of Neurosurgical Anesthesiology)
Source: Journal of Neurosurgical Anesthesiology - September 8, 2016 Category: Anesthesiology Tags: Clinical Reports Source Type: research