Nerve echogenicity and intranerve CSA variability in high-resolution nerve ultrasound (HRUS) in chronic inflammatory demyelinating polyneuropathy (CIDP)
ConclusionEchogenicity of the arm nerves in CIDP may be used as a prognostic marker, but not as a follow-up tool for evaluating clinical changes. Further studies in a larger cohort are needed to confirm these results. (Source: Journal of Neurology)
Source: Journal of Neurology - December 15, 2018 Category: Neurology Source Type: research

Prophylactic treatment of migraine with and without aura with acetyl- dl -leucine: a case series
(Source: Journal of Neurology)
Source: Journal of Neurology - December 13, 2018 Category: Neurology Source Type: research

Correction to: Jean Baptiste Octave Landry (1826 –1865)
The original version of this article unfortunately contained a mistake. Title was incorrect. The corrected title is given below. (Source: Journal of Neurology)
Source: Journal of Neurology - December 13, 2018 Category: Neurology Source Type: research

Imaging in the diagnosis of progressive supranuclear palsy
(Source: Journal of Neurology)
Source: Journal of Neurology - December 12, 2018 Category: Neurology Source Type: research

Characteristics and relative factors of headache caused by cervicocerebral artery dissection
ConclusionThe headache and neck pain caused by CAD is a moderate to severe pain occurring suddenly. The pain nature may be diverse but mostly like throbbing and pulsating. When the dissected artery is located in the posterior circulation, the pain is mostly in the occipital region, and mostly in the temporal region when the dissected artery is located in the anterior circulation. The pain can occur in ipsilateral, bilateral, or contralateral of the dissection. In addition, several factors might contribute to the occurrence of headache and neck pain. (Source: Journal of Neurology)
Source: Journal of Neurology - December 12, 2018 Category: Neurology Source Type: research

Pretreatment cerebral microbleeds and symptomatic intracerebral hemorrhage post-thrombolysis: a systematic review and meta-analysis
ConclusionsThe pretreatment CMBs were associated with increased incidence of sICH and PFO in acute ischemic stroke patients receiving IVT. However, it was not convincing enough to set the presence of CMBs as contraindication to IVT. (Source: Journal of Neurology)
Source: Journal of Neurology - December 12, 2018 Category: Neurology Source Type: research

Guillain –Barré syndrome in Denmark: a population-based study on epidemiology, diagnosis and clinical severity
AbstractObjectivesTo describe the epidemiology and clinical heterogeneity of Guillain –Barré syndrome (GBS) in Denmark and to compare a population-based cohort to prospectively included patients in the International GBS Outcome Study (IGOS).MethodsThe incidence rate (IR) of GBS in Denmark from September 2012 to December 2015, applying the National Institute of Neurological Disorders and Stroke (NINDS) diagnostic criteria, was estimated and the level of diagnostic certainty was described with the Brighton criteria. All cases registered with a diagnosis of GBS or other inflammatory neuropathies in the Danish Nat...
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Metronidazole-induced encephalopathy: a systematic review
ConclusionMetronidazole-induced encephalopathy should be considered in patients presenting with neurological symptoms in relation to newly initiated or prolonged metronidazole treatment. MRI changes are highly characteristic and specific. Patients with liver disease are at increased risk. Prognosis is good if recognized early. (Source: Journal of Neurology)
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Pioneers in neurology: Michel Jouvet (1925 –2017)
(Source: Journal of Neurology)
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Clinical feasibility of 1-min ultrafast brain MRI compared with routine brain MRI using synthetic MRI: a single center pilot study
ConclusionsAlthough the overall image quality and anatomical delineation of the 1-min ultrafast MRI were inferior to those of the routine brain MRI protocol, the ultrafast protocol showed at least sufficient image quality. Therefore, this protocol may be an option in specific clinical situations involving non-cooperative, restless, or pediatric patients, or patients with time-critical disease such as stroke. Further study is required to validate our findings. (Source: Journal of Neurology)
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Gait festination in parkinsonism: introduction of two phenotypes
AbstractGait festination is one of the most characteristic gait disturbances in patients with Parkinson ’s disease or atypical parkinsonism. Although festination is common and disabling, it has received little attention in the literature, and different definitions exist. Here, we argue that there are actually two phenotypes of festination. The first phenotype entails a primary locomotion disturbance , due to the so-called sequence effect: a progressive shortening of step length, accompanied by a compensatory increase in cadence. This phenotype strongly relates to freezing of gait with alternating trembling of the leg...
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Vibrotactile feedback improves balance and mobility in patients with severe bilateral vestibular loss
AbstractThe impact of vibrotactile feedback of the gravity vector, provided by a “balance” belt worn around the waist, was evaluated in 39 patients with a severe bilateral vestibular loss, confirmed by extensive laboratory testing and suffering from a low quality of life, mainly due to imbalance. The mobility and balance score (MBS) of all patients prior to the use of the be lt was equal or less than 5 out of a scale of 10. Thirty-one out of the 39 patients experienced the effect of the belt on their balance and mobility as positive in a preselection trial of 2 h in the hospital. The 31 positive responders...
Source: Journal of Neurology - December 5, 2018 Category: Neurology Source Type: research

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS)
ConclusionsIdentification of risk factors for short-term cognitive change in newly diagnosed MS or CIS is insufficient using only demographic, clinical and conventional MRI data. Change-sensitive, re-test reliable cognitive tests and more sophisticated predictors need to be employed in future clinical trials and cohort studies of early-stage MS to improve prediction. (Source: Journal of Neurology)
Source: Journal of Neurology - December 4, 2018 Category: Neurology Source Type: research

ANO10 mutational screening in recessive ataxia: genetic findings and refinement of the clinical phenotype
AbstractAutosomal recessive cerebellar ataxia type 3 (ARCA3) is a rare inherited disorder caused by mutations in theANO10 gene. The disease is characterized by slowly progressive spastic ataxia variably associated with motor neuron involvement, epilepsy, and cognitive decline. We performed mutational screening in 80 patients with sporadic or autosomal recessive adult-onset ataxia. We identified 11ANO10 gene variants in 10 patients from 8 families (10%): 4 mutations were previously described and 7 were novel. Age at onset ranged between 27 and 53  years. All patients presented ataxia, pyramidal signs and cerebellar atr...
Source: Journal of Neurology - December 4, 2018 Category: Neurology Source Type: research

Discontinuation of teriflunomide and dimethyl fumarate in a large Italian multicentre population: a 24-month real-world experience
ConclusionsIn a real-world setting, pwRRMS on TRF and DMF had similar discontinuation rates over 24 months. Male pwRRMS on DMF with a previous history of therapeutic failure are at more risk of discontinuation therapy. (Source: Journal of Neurology)
Source: Journal of Neurology - December 4, 2018 Category: Neurology Source Type: research

Recessive PYROXD1 mutations cause adult-onset limb-girdle-type muscular dystrophy
ConclusionPYROXD1 variants can cause an adult-onset slowly progressive LGMD-type phenotype. (Source: Journal of Neurology)
Source: Journal of Neurology - December 4, 2018 Category: Neurology Source Type: research

Treatment escalation leads to fewer relapses compared with switching to another moderately effective therapy
AbstractBackgroundPatients with multiple sclerosis who experience disease breakthrough often switch disease-modifying therapy (DMT).ObjectiveTo compare treatment effectiveness of switch to highly effective DMT (heDMT) with switch to moderately effective DMT (meDMT) for patients who switch due to disease breakthrough defined as at least one relapse within 12  months of their treatment switch.MethodsWe retrieved data from The Danish Multiple Sclerosis Registry on all relapsing-remitting MS patients with expanded disability status scale (EDSS) less than 6 who experienced disease breakthrough. We used propensity score mat...
Source: Journal of Neurology - December 4, 2018 Category: Neurology Source Type: research

A controlled inflammation and a regulatory immune system are associated with more favorable prognosis of progressive multifocal leukoencephalopathy
ConclusionsViral loads in the cerebrospinal fluid, a controlled inflammatory response mediated by CD4- and CD8-positive T cells, and plasma cells are associated with PML prognosis. Our findings further indicate that regulatory plasma cells may regulate inflammatory T-cell activity via a PD-1/PD-L1 immuno-checkpoint pathway, thereby protecting the uninfected brain from excessive immune-mediated damage during an active JC virus infection. (Source: Journal of Neurology)
Source: Journal of Neurology - December 3, 2018 Category: Neurology Source Type: research

Efficacy of pregabalin in post-traumatic peripheral neuropathic pain: a randomized, double-blind, placebo-controlled phase 3 trial
AbstractThe growing need for symptomatic treatment of post-traumatic neuropathic pain (PTNP) continues  to be unmet. Studies evaluating the efficacy of pregabalin for reducing neuropathic pain following trauma and surgery yielded positive results over ≤ 8-week treatment. To assess the efficacy and tolerability of pregabalin over 3 months in patients with PTNP, a randomized, double-blind, placebo -controlled, parallel-group trial evaluated patients with PTNP at 101 centers in 11 countries—the longest, largest such trial. Adults diagnosed with PTNP were randomly assigned (1:1) to 15 weeks of pregabalin (...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Risk factors for self-harm in people with epilepsy
ConclusionPeople with epilepsy have elevated self-harm risk, especially in the first year following diagnosis. Clinicians should adequately monitor these individuals and be especially vigilant to self-harm risk in people with epilepsy and comorbid mental illness, frequent healthcare service contact, those taking multiple AEDs and during treatment augmentation. (Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Relation between functional connectivity and disability in multiple sclerosis: a non-linear model
AbstractObjectiveTo characterize the relation between brain functional connectivity and disability in patients with multiple sclerosis; to investigate the existence of critical values of both disability and functional connectivity corresponding to exhaustion of functional adaptive mechanisms.MethodsHundred-and-nineteen patients with no-to-severe disability and 42 healthy subjects were studied via 3T resting state functional MRI. Out of 116 regions extracted from Automated Anatomical Labeling atlas, pairs of regions whose functional connectivity correlated with Expanded Disability Status Score were identified. In patients, ...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Structural signature in SCA1: clinical correlates, determinants and natural history
AbstractSpinocerebellar ataxia type 1 is an autosomal dominant disorder caused by a CAG repeat expansion inATXN1, characterized by progressive cerebellar and extracerebellar symptoms. MRI-based studies in SCA1 focused in the cerebellum and connections, but there are few data about supratentorial/spinal damage and its clinical relevance. We have thus designed this multimodal MRI study to uncover the structural signature of SCA1. To accomplish that, a group of 33 patients and 33 age-and gender-matched healthy controls underwent MRI on a 3T scanner. All patients underwent a comprehensive neurological and neuropsychological ev...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Elevated C-reactive protein and white blood cell count at admission predict functional outcome after non-aneurysmal subarachnoid hemorrhage
ConclusionElevated C-reactive protein and WBC count at admission were associated with unfavorable outcome after non-aneurysmal SAH. (Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Nerve sheath tumours
(Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Serum irisin is upregulated in patients affected by amyotrophic lateral sclerosis and correlates with functional and metabolic status
AbstractIntroductionThe progression of amyotrophic lateral sclerosis (ALS) leads to a decline of the nutritional status that represents an independent prognostic factor for survival. Recent studies recognize the muscle tissue as an endocrine organ able to release several molecules, called myokines. Among them, irisin seems to be involved in the regulation of metabolism, body weight and development and function of the nervous system.Objectives(1) To evaluate irisin serum levels in patients with ALS, with comparison to healthy subjects; (2) to assess the possible association of circulating irisin levels of ALS patients with ...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Multifocal motor neuropathy in Austria: a nationwide survey of clinical features and response to treatment
The objective of this study was to evaluate epidemiological, clinical, and laboratory features of MMN patients and their response to treatment in Austria and to compare these data with those from the literature.MethodsAnonymized demographic and clinical data about MMN patients until 31.12.2017 were collected from registered Austrian neurologists. Exploratory statistics on clinical and laboratory features as well as treatment regimens and responses were performed.Results57 Patients with MMN were identified, resulting in a prevalence of 0.65/100.000. Mean age of onset was 44.1  ± 13.1 years, the diagnost...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Perfusion-CT imaging in epileptic seizures
ConclusionIn patients with acute epileptic seizures, regional hyperperfusion on PCT may suggest an ongoing or recently resolved SE, whereas hypoperfusion may be due to post-ictal state or simultaneous AIS. These observations might help attributing focal deficits to epileptic seizures rather than stroke, allowing for targeted therapy. (Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Early MRI-negative posterior circulation stroke presenting as acute dizziness
AbstractThe aim of this study was to determine the frequency, clinical and radiological features, and efficacy of clinical evaluation and perfusion-weighted imaging (PWI) for the prediction of final stroke in patients with DWI/MRI-negative posterior circulation stroke (PCS) presenting acute dizziness/vertigo. From our comprehensive prospective stroke registry of acute ischemic stroke during a 7-year period, we identified 1846 consecutive patients with PCS, 850 of whom presented with acute dizziness/vertigo. Of these 850 patients, initial DWI-MRI was negative in 35 (4.1%). In these 35 patients, dizziness/vertigo was acute p...
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

A smartphone camera reveals an ‘invisible’ Parkinsonian tremor: a potential pre-motor biomarker?
(Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Effect of mechanical thrombectomy alone or in combination with intravenous thrombolysis for acute ischemic stroke
ConclusionsOur study suggests that mechanical thrombectomy alone is effective and safe in patients with contraindications to intravenous thrombolysis. Preceding use of IVT in eligible patients was not associated with increased harm or benefit. Randomized controlled trials are needed to clarify whether intravenous thrombolysis before mechanical thrombectomy is associated with additional benefit. (Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

A closer look at ping-pong gaze: an observational study and literature review
ConclusionsPPG is a sign with localizing value that suggests hemispheric damage and asymmetric PPG might help to predict lateralization of the lesions. Acute ischemic stroke is the most common cause of PPG. Etiology and initial outcome are likely important prognostic factors of PPG. (Source: Journal of Neurology)
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research

Admission diagnoses of patients later diagnosed with autoimmune encephalitis
ConclusionsThese data show the broad spectrum of initial symptoms of AE; the correct initial diagnosis of AE is often missed or delayed. Hence, clinicians in neurological and psychiatric hospitals should consider AE in the differential diagnosis of cases with atypical clinical presentations. (Source: Journal of Neurology)
Source: Journal of Neurology - November 12, 2018 Category: Neurology Source Type: research

Anti-ganglioside antibody-associated acute unilateral peripheral vestibulopathy
(Source: Journal of Neurology)
Source: Journal of Neurology - November 12, 2018 Category: Neurology Source Type: research

A case –control study of the determinants for cervicocerebral artery dissection
AbstractBackgroundCervicocerebral artery dissection (CAD) is a major cause of ischemic stroke in young adults. There are many existing studies on determinants for CAD; however, they are still not totally defined. We conduct the study to further investigate the determinants for CAD based on ischemic stroke patients.Methods81 ischemic stroke patients with CAD were enrolled in the CAD stroke group and 84 ischemic stroke patients without CAD were enrolled in the non-CAD stroke group. Their clinical data, such as age, gender, vascular risk factors, headache and neck pain and clinical laboratory data, were collected to analyze t...
Source: Journal of Neurology - November 12, 2018 Category: Neurology Source Type: research

Validation of CSF free light chain in diagnosis and prognosis of multiple sclerosis and clinically isolated syndrome: prospective cohort study in Buenos Aires
ConclusionKFLCs have a high sensitivity and specificity for the diagnosis of MS. FLC concentrations at CIS diagnosis were not significantly higher in CIS-converters. (Source: Journal of Neurology)
Source: Journal of Neurology - November 1, 2018 Category: Neurology Source Type: research

StartReact during gait initiation reveals differential control of muscle activation and inhibition in patients with corticospinal degeneration
AbstractCorticospinal lesions cause impairments in voluntary motor control. Recent findings suggest that some degree of voluntary control may be taken over by a compensatory pathway involving the reticulospinal tract. In humans, evidence for this notion mainly comes from StartReact studies. StartReact is the acceleration of reaction times by a startling acoustic stimulus (SAS) simultaneously presented with the imperative stimulus. As previous StartReact studies mainly focused on isolated single-joint movements, the question remains whether the reticulospinal tract can also be utilized for controlling whole-body movements. ...
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

Peripheral tumor necrosis factor-a-induced protein 8-like 2 mRNA level for predicting 3-month mortality of patients with acute ischemic stroke
This study aimed to investigate TIPE2 mRNA in peripheral blood mononuclear cells for predicting 3-month functional outcomes and mortality of patients with acute ischemic stroke. A total of 182 consecutive patients were prospective collected, and there were 55 (30.2%) patients with unfavorable outcome and 33 (18.1%) patients died at the end of 3  months. The area under the operating characteristic curve (AUC) for TIPE2 mRNA was 0.810 (95% CI 0.733–0.886) for mortality and 0.740 (95% CI 0.662–0.818) for unfavorable outcome. The model incorporating National Institutes of Health Stroke Scale (NIHSS) plus TIPE2...
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

Delayed treatment of MS is associated with high CSF levels of IL-6 and IL-8 and worse future disease course
ConclusionsDelayed diagnosis and treatment initiation are associated with higher CSF levels of IL-6 and IL-8 in RR-MS, leading to worsening disease course and poor response to treatments. (Source: Journal of Neurology)
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

Anti-epileptics and pregnancy: an update
(Source: Journal of Neurology)
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

Worse endovascular mechanical recanalization results for patients with in-hospital onset acute ischemic stroke
ConclusionThe recognition, assessment and pre-interventional procedures of patients with in-hospital strokes and subsequent mechanical thrombectomy are favorable. Nevertheless, in-hospital stroke patients display inferior recanalization results and poorer clinical outcomes. Furthermore, we find mechanical thrombectomy seems safe for treatment of in-hospital strokes. (Source: Journal of Neurology)
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

The Brief International Cognitive Assessment in Multiple Sclerosis (BICAMS): results from the German validation study
AbstractBackgroundRecent research has convincingly shown that the ability to work mainly depends on the cognitive status in multiple sclerosis (MS). An international committee of experts recommended a brief neuropsychological battery to evaluate cognitive performance in MS. BICAMS comprises three tests, the Symbol Digit Modalities Test (SDMT), the learning trials of the California Verbal Learning Test II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R).ObjectiveTo validate BICAMS on a sample of German MS patients and healthy controls (HCs).MethodsAccording to the international guidelines for validation, e...
Source: Journal of Neurology - October 12, 2018 Category: Neurology Source Type: research

The role of clinical and neuroimaging features in the diagnosis of CADASIL
ConclusionsA careful familial history collection and neuroradiological assessment can identify patients in whomNOTCH3 genetic testing has a higher yield. (Source: Journal of Neurology)
Source: Journal of Neurology - October 11, 2018 Category: Neurology Source Type: research

High-sensitivity cardiac troponin T and severity of cerebral white matter lesions in patients with acute ischemic stroke
ConclusionElevated hs-cTnT levels were associated with extent of WML in acute stroke patients. Further studies are needed to assess whether hs-cTnT can be used to identify stroke patients at risk for cognitive decline. (Source: Journal of Neurology)
Source: Journal of Neurology - October 11, 2018 Category: Neurology Source Type: research

Functioning and quality of life in patients with neuropathy associated with anti-MAG antibodies
AbstractAlthough anti-myelin-associated glycoprotein (MAG) antibody neuropathy is reported as a slowly progressive disease, it can lead to significant disability and impairment of health-related quality of life (HR-QoL) and social participation. The aim of this cross-sectional study was to evaluate the functioning and HR-QoL determinants in 67 patients with anti-MAG neuropathy in terms of the International Classification of Functioning, Disability, and Health (ICF). Evaluations included: Medical Research Council (MRC) sum score, Sensory Modality Sum score (SMS), Berg balance scale (BBS), Fatigue Severity Scale (FSS), Visua...
Source: Journal of Neurology - October 10, 2018 Category: Neurology Source Type: research

The clinical features and outcome of scan-negative and scan-positive cases in suspected cauda equina syndrome: a retrospective study of 276 patients
ConclusionsThe data support a model in which scan-negative cauda equina syndrome arises as an end pathway of acute pain, sometimes with partly structural findings and vulnerability to functional disorders. (Source: Journal of Neurology)
Source: Journal of Neurology - October 8, 2018 Category: Neurology Source Type: research

Management of patients with stroke treated with direct oral anticoagulants
AbstractSince their market approval, direct oral anticoagulants (DOACs) are being increasingly used for stroke prevention in patients with atrial fibrillation. However, the management of DOAC-treated patients with stroke poses several challenges for physicians in everyday clinical practice, both in the acute setting and in long-term care. This has spurred extensive research activity in the field over the past few years, which we review here. (Source: Journal of Neurology)
Source: Journal of Neurology - October 6, 2018 Category: Neurology Source Type: research

Short-term and long-term effects of immunoadsorption in refractory chronic inflammatory demyelinating polyneuropathy: a prospective study in 17 patients
AbstractObjectiveChronic inflammatory demyelinating polyneuropathy (CIDP) is a rare, autoimmune-inflammatory disease of the peripheral nervous system. Recently, various immunoglobulin G4 (IgG4) type auto-antibodies have been described in patients with CIDP which can effectively be removed by immunoadsorption (IA). Therefore, we prospectively evaluated the therapeutic effect of IA in 17 patients with progressive CIDP not responding to other treatment.MethodsWe prospectively evaluated the course of disease of 17 patients with CIDP who had insufficiently responded to steroids and/or IVIg previously and who received at least o...
Source: Journal of Neurology - October 6, 2018 Category: Neurology Source Type: research

Cerebral small vessel disease: neuroimaging markers and clinical implication
AbstractCerebral small vessel disease (CSVD) is a broad category of cerebrovascular diseases which primarily affect the perforating arterioles, capillaries and venules with multiple distinct etiologies. In spite of distinctive pathogenesis, CSVD shares similar neuroimaging markers, including recent small subcortical infarct, lacune of presumed vascular origin, white matter hyperintensity of presumed vascular origin, perivascular space and cerebral microbleeds. The radiological features of neuroimaging markers are indicative for etiological analysis. Furthermore, in sporadic arteriosclerotic pathogenesis associated CSVD, th...
Source: Journal of Neurology - October 5, 2018 Category: Neurology Source Type: research

Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study
AbstractIntroductionWe aimed to disprove an in-hospital off-hour effect in stroke patients by adjusting for disease severity and poor prognostic findings on imaging.Patients and methodsOur study included 5378 patients from a single center prospective stroke registry of a large teaching hospital in the Netherlands, admitted between January 2003 and June 2015. Patients were categorized by admission time, off-hours (OH) or working hours (WH). The in-hospital mortality, 7-day mortality, unfavorable functional outcome (modified Rankin scale  >  2) and discharge to home were analyzed. Results were adjusted for a...
Source: Journal of Neurology - October 5, 2018 Category: Neurology Source Type: research

James Crichton-Browne (1840 –1938)
(Source: Journal of Neurology)
Source: Journal of Neurology - October 4, 2018 Category: Neurology Source Type: research