Mechanical thrombectomy in patients with acute ischemic stroke in the USA before and after time window expansion
Conclusions The window expansion for mechanical thrombectomy for patients with acute ischemic stroke was associated with an increase in the numbers of mechanical thrombectomy procedures and performing hospitals with a reduction of in-hospital mortality in the USA. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Kwok, C. S., Gillani, S. A., Bains, N. K., Gomez, C. R., Hanley, D. F., Ford, D. E., Hassan, A. E., Nguyen, T. N., Siddiq, F., Spiotta, A. M., Qureshi, A. I. Tags: Ischemic stroke Source Type: research

The digital motor output: a conceptual framework for a meaningful clinical performance metric for a motor neuroprosthesis
In recent years, the majority of the population has become increasingly reliant on continuous and independent control of smart devices to conduct activities of daily living. Upper extremity movement is typically required to generate the motor outputs that control these interfaces, such as rapidly and accurately navigating and clicking a mouse, or activating a touch screen. For people living with tetraplegia, these abilities are lost, significantly compromising their ability to interact with their environment. Implantable brain computer interfaces (BCIs) hold promise for restoring lost neurologic function, including motor n...
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Sawyer, A., Cooke, L., Ramsey, N. F., Putrino, D. Tags: New devices New devices and techniques Source Type: research

'Armed kyphoplasty with posterior stabilization avoids corpectomy in complex thoracolumbar spine fractures: a case series
Conclusions Combined AKP and PS is feasible and effective in the treatment of complex thoracolumbar fractures of all etiologies. AKP avoided highly invasive corpectomy. Anterior and posterior support ensured stability, preventing implant failure and re-fracture. The complication rate was low compared with more invasive traditional 360° open surgical approaches. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Bertulli, L., Pileggi, M., Marchi, F., Scarone, P., Cianfoni, A. Tags: Editor''s choice, New devices New devices and techniques Source Type: research

Armed kyphoplasty-the future?
Percutaneous vertebral augmentation with polymethyl methacrylate (PMMA) in combination with, or without percutaneous implants are typically indicated in fractures involving the anterior and middle column. These techniques decrease fracture related pain and provide improved anterior column stability. When fractures or lytic neoplasms involve the middle and posterior columns, however, anterior and posterior surgical fixation and stabilization are considered the standard of care. Well documented high complication and mortality risks are seen in the literature regarding such invasive open surgeries, especially in patients with...
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Brook, A. D., Clerk-Lamalice, O., De Leacy, R. A., Brook, A. L., Hirsch, J. A. Tags: Commentary Source Type: research

Management of wide-neck aneurysms in 2024: how does one make the best treatment decision when there are so many good options?
A middle-aged patient walks into the office for the first time with an unruptured, medium sized, wide-neck middle cerebral artery (MCA) aneurysm incorporating both M2 origins into the aneurysm neck. What is the best management for this patient? What is the safest and most effective treatment option? How does one make the decision when there are so many good options currently available? Wide-neck aneurysms (WNAs) are defined as those with a neck width >4 mm, a dome to neck ratio <2, or both features.1 They may be ruptured or unruptured. These aneurysms are more challenging to treat and require more advanced techniques...
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Mascitelli, J. R. Tags: Basic science Source Type: research

Correction: Emergent carotid stenting versus no stenting for acute ischemic stroke due to tandem occlusion: a meta-analysis
Diana F, Romoli M, Toccaceli G, et al.Emergent carotid stenting versus no stenting for acute ischemic stroke due to tandem occlusion: a meta-analysis. J NeuroIntervent Surg 2023;15:428–433. Since this paper was first published, figure 3 has been updated, because an article was wrongly included in the analysis. The OR, 95 CI and weight categories have been updated. However, point estimate remains unchanged, and only a minor change to 95%CI emerged. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Tags: Correction Source Type: research

Correspondence on 'Acute ischemic stroke outcomes in patients with COVID-19: a systematic review and meta-analysis by Ferrone et al
We had the pleasure of reading the article ‘Acute ischemic stroke outcomes in patients with COVID-19: a systematic review and meta-analysis’ by Ferrone et al. with great interest.1 In particular, the reduced odds of home discharge for patients with stroke who have COVID-19 presents an interesting insight into the management challenges while caring for these patients. However, we would like to highlight some concerns about the methodology of the study. Heterogeneity is defined as observed intervention effects being more different from each other than one would expect due to random error (chance) alone.2 For the ...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Muzaffar, T., Danial, A., Ahmed, M. K. Tags: COVID-19 Letter Source Type: research

Response to: Correspondence on "Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019" by Cole
In this study, missing information includes aneurysm location, aneurysm size, why a treatment was chosen, whether a pathology was a comorbidity or a complication, if there was an external ventricular drain, and all the details regarding the aneurysmal disease process. In short, we do not know if these cohorts are comparable." We fully agree with this major limitation of our study. When conducting the study we were aware of this limitation and included two paragraphs describing details of it in the Limitations section at the end of the discussion. Furthermore, we decided against sophisticated matching or weighting methods b...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Kaier, K., Haverkamp, C., Meckel, S. Tags: Letter Source Type: research

Correspondence on 'Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019 by Haverkamp et al
In this study, missing information includes aneurysm location, aneurysm size, why a treatment was chosen, whether a pathology was a comorbidity or... (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Cole, T. S. Tags: Letter Source Type: research

Stereotactic-guided direct orbital puncture for treatment of orbital arteriovenous fistula
The patient presented with left-sided chemosis, exophthalmos, and progressive visual loss. Cerebral angiography ed a left orbital arteriovenous malformation and an associated hematoma, with the point of fistulation between the left ophthalmic artery and the anterior section of the inferior ophthalmic vein, with retrograde flow through the superior ophthalmic vein. Transvenous embolization through the anterior facial and angular veins was unsuccessful, with residual shunting. Stereotactic-guided direct venous puncture and Onyx embolization was subsequently performed in the hybrid operating room (OR) to cure the fistula. A s...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Robledo, A., Frank, T. S., Karas, P. J., Shaltoni, H., O'Leary, S., Darling, R., Kan, P. Tags: Technical video Source Type: research

Now that the door is open: an update on ischemic stroke pharmacotherapeutics for the neurointerventionalist
The last 10 years have seen a major shift in management of large vessel ischemic stroke with changes towards ever-expanding use of reperfusion therapies (intravenous thrombolysis and mechanical thrombectomy). These strategies ‘open the door’ to acute therapeutics for ischemic tissue, and we should investigate novel therapeutic approaches to enhance survival of recently reperfused brain. Key insights into new approaches have been provided through translational research models and preclinical paradigms, and through detailed research on ischemic mechanisms. Additional recent clinical trials offer exciting salvos i...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Fraser, J. F., Pahwa, S., Maniskas, M., Michas, C., Martinez, M., Pennypacker, K. R., Dornbos, D. Tags: Vascular neurology Source Type: research

Symptomatic non-stenotic carotid disease: current challenges and opportunities for diagnosis and treatment
Symptomatic non-stenotic carotid plaques (SyNC) are an under-researched and under-recognized source of stroke. Various imaging markers of non-stenotic carotid plaques that are associated with stroke risk have been identified, but these causal relationships need to be confirmed in additional prospective studies. Currently, there exists neither a standardized SyNC definition nor a dedicated set of imaging protocols, although researchers have started to address these shortcomings. Moreover, many neuroradiologists are still unaware of the condition, and hence do not comment on high-risk plaque features other than stenosis in t...
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Ospel, J. M., Kappelhof, M., Ganesh, A., Kallmes, D. F., Brinjikji, W., Goyal, M. Tags: Vascular neurology Source Type: research

Robotically assisted deployment of flow diverter stents for the treatment of cerebral and cervical aneurysms
Conclusion Robot-assisted flow diverter stent deployment using the CorPath GRX platform is feasible and appears to be safe. Larger, in-depth studies of the technique’s safety and benefits are now warranted. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Chivot, C., Bouzerar, R., Peltier, J., Lefranc, M., Yzet, T. Tags: New devices New devices and techniques Source Type: research

Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms
Conclusions This first-of-its-kind robotic-assisted neurovascular trial demonstrates the effectiveness and safety of the CorPath GRX System for endovascular embolization of cerebral aneurysm procedures. Trial registration number NCT04236856 (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Mendes Pereira, V., Rice, H., De Villiers, L., Sourour, N., Clarencon, F., Spears, J., Tomasello, A., Hernandez, D., Cancelliere, N. M., Liu, X. Y. E., Nicholson, P., Costalat, V., Gascou, G., Mordasini, P., Gralla, J., Martinez-Galdamez, M., Galvan Ferna Tags: Open access, New devices New devices and techniques Source Type: research

Advancements in super-selective catheterization and drug selection for intra-arterial chemotherapy for retinoblastoma: a 15-year evolution
Conclusions The overall rate of successful catheterization and IAC started high and has improved over 15 years, and catheterization-related complications are rare. There has been a significant trend towards triple chemotherapy over time. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - March 14, 2024 Category: Neurosurgery Authors: Kocharian, G., Gobin, Y. P., Kharas, N., Knopman, J., Francis, J. H., Abramson, D. H. Tags: New devices New devices and techniques Source Type: research