P166/253 Safety and efficacy of the dual-layer CGuard stent for the treatment of tandem occlusions - a comparative study with the carotid wallstent
ConclusionIn our series, the rate of in-stent occlusions after emergent CAS was in tendency lower with the dual-layer CGuard when compared to the monolayer Wall stent. Further data is needed to evaluate the potential benefit of the design in more detail.Disclosure of InterestFD serves as a proctor/consultant for Cerenovus, Microvention, Balt, Cerus Endovascular, received scientific grant from Cerenovus and speakers honoraria from Acandis, Asahi, Stryker. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Mousa, Z., Paech, D., Bode, F., Gronemann, C., Petzold, G., Dorn, F. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P165/237 Development and Validation of a novel stenosis model for percutaneous transluminal angioplasty training
ConclusionThe authors propose a novel ICA stenosis simulation model for training of PTA.The model provides a realistic and replicable method for standardized procedural training.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Ramdani, N., Anna, K., Tuan, N., Jonte, S., Dieter, K., Fabian, F., Lukas, M., Jens, F., Maxim, B., Helena, G. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P164/236 Antithrombotic regimen in emergent carotid stenting for acute ischemic stroke due to tandem lesion: a meta-analysis of aggregate data
ConclusionsIn AIS due to tandem occlusion, the periprocedural antithrombotic regimen of eCAS seems to have a marginal effect on good functional outcome. Overall, high intensity antithrombotic therapy may provide a marginal benefit on good functional outcome and carotid stent patency without a significant increase in risk of sICH.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Diana, F., Abdalkader, M., Behme, D., Li, W., Maurer, C. J., Pop, R., Hwang, Y.-H., Bartolini, B., Ros, V. D., Bracco, S., Cirillo, L., Marnat, G., Katsanos, A., Kaesmacher, J., Fischer, U., Sousa, D. A. d., Peschillo, S., Zini, A., Tomasello, A., Ribo, M Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P163/235 Thrombolysis and collateral flow in interhospital transfer for thrombectomy: implications for recanalization and infarct growth
ConclusionCollateral flow and thrombolysis may have a positive interaction in macrovascular recanalization. However, thrombolysis does not appear to interfere with collateral-mediated infarct growthDisclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Sousa, J., Bernardo-Castro, S., Machado, R. B., Maia, C., Cruz, L., Simoes, J., Martins, A. I., Bras, A., Almendra, L., Nunes, C., Machado, C., Rodrigues, B., Veiga, R., Nunes, C., Silva, F., Pereira R Cordeiro Santo, G. A., Machado, E., Freitas, J. S. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P162/231 Good Clinical Outcome Decreases With Number of Retrieval Attempts in Posterior Circulation Stroke Thrombectomy
ConclusionSuccessful reperfusion within the first three retrieval attempts is associated with improved clinical outcome compared to patients without reperfusion. We conclude that at least three retrieval attempts should be performed in EVT of posterior circulation strokes.Disclosure of InterestDr Thomall: personal fees from Acandis, grants and personal fees from Bayer, personal fees from Bristol Myers Squibb/Pfizer, Boehringer Ingelheim, Daiichi Sankyo, Portola, Stryker outside the submitted work. Dr Fiehler reports grants and personal fees from Acandis, Cerenovus, Medtronic, Microvention, personal fees from Penumbra, and ...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Flottmann, F., Winkelmeier, L., Brekenfeld, C., Thomalla, G., Fiehler, J., Maros, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P161/225 Proximal balloon-guided catheter with flow inversion vs. distal filter protection during the carotid stent placement, a seven years experiences in a Colombia reference center
ConclusionIn our study the proximal balloon-guided catheter and the distal filter protection device as protection devices during the carotid stenting didn’t show significant differences regarding complications related to the system.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Garcia, D. M., Garcia, O., Correa, P., Vera, D. D., Valenzuela, C., Serrano, S., Reyes, A., Ferreira, C., Vargas, O. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P160/223 Acute stroke with treatment of tandem lesions under triple antiplatelet therapy: procedural saftey, stent patency and outcome at 90 days
ConclusionTL treatment under triple AP was safe in our experience, resulting in a low rate of restenosis and with favorable outcome in 92%. The influence of comorbidities on restenosis could be negligible within the described follow-up period.Disclosure of InterestPhilipp von Gottberg: Nothing to disclose.Ali Khanafer: Nothing to discloseVictoria Hellstern: Proctering for phenox GmbH.Alexandru Cimpocca: Nothing to disclose.Hans Henkes: Proctoring for phenox GmbH, Co-Founder and Co-Owner of CONTARA GmbH (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Philipp, V. G., Khanafer, A., Hellstern, V., Cimpoca, A., Bäzner, H., Henkes, H. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P159/213 Early clinical surrogates for functional outcome after mechanical thrombectomy in M2 occlusions compared to M1 occlusions
Conclusion24h NIHSS was identified as best surrogate for long-term functional outcome after thrombectomy for patients with M1 and M2 occlusion, while optimal cut-offs to predict good and excellent outcome were 1 NIHSS-point higher in M2 occlusions compared to M1 occlusions.Disclosure of InterestHK has financial interest in Eppdata GmbH.GT received fees as consultant and lecturer from Acandis, Alexion, Amarin, Boehringer Ingelheim, Bayer, BMS/Pfizer, Daiichii Sankyo and Portola. He serves in the board of the TEA Stroke Study and of ESO.JF is consultant for Cerenovus, Medtronic, Microvention, Penumbra, Phenox, Roche, Stryker...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Broocks, G., Bechstein, M., Winkelmeier, L., Faizy, T., Brekenfeld, C., Flottmann, F., Paula Hanning, U. M., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P158/212 The first pass effect: the initial real-life experience of the University Clinical centre of Serbia
ConclusionDespite shorter time intervals and higher frequency of recanalization rate of the FPE group, no difference was observed in relation to clinical and safety outcomes after 90 days of AIS. In order to better understand the FPE and its predictors, further studies are needed in form of randomized controlled clinical studies.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Mircic, U., Vukasinovic, I., Nedeljkovic, Z., Pirkovic, I., Nestorovic, D., Cvetic, V., Ercegovac, M., Jovanovic, D., Berisavac, I., Stanarcevic, P. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P157/210 Comparison of adjustable vs self-expanding stent-retrivers for mechanical thrombectomy in large vessel occlusion
ConclusionTigertriever had a significantly higher successful first pass revascularization rate and shorter groin-to-revascularization time in the analysis done before and after propensity score matching with stent-like stent-retrievers.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Piasecki, P., Wierzbicki, M., Narloch, J., Debiec, A., Staszewski, J. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P156/208 Association between arterial diameter and outcome in acute M2 occlusive ischemic stroke patients treated with endovascular thrombectomy
ConclusionThis study demonstrated that the lowest quartile of M2 diameter was associated with procedural complication in the acute M2 occlusion patients treated with EVT. However, clinical outcome was not differed.Disclosure of InterestNothing to disclose (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kim, J. Y., Kim, D. Y., Kang, J., Kim, B. J., Han, M.-K., Bae, H.-J., Baik, S. H., Jung, C. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P155/200 Usefulness of quadri-axial system in mechanical thrombectomy in acute ischemic stroke: redefining the boundaries of trans-femoral access
ConclusionQAS via TFA for MT in AIS is a safe and effective technique, even in challenging cases, allowing faster and more successful procedures without increasing complications. QAS could redefine and widen the boundaries of TFA in AIS.Disclosure of InterestNothing to disclose. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Politi, M. A., Kuncha, G., Conte, M., Cavallaro, T., Corsale, G., Borzi, S. R., Monaco, E., Travali, M., Concetto, C. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P154/193 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy: a randomized in vitro evaluation
ConclusionsWhen facing fragment-prone clots, the filter-tip SR significantly reduces the number of large clots (>1 mm) that embolize distally during an MT procedure, potentially increasing the chances of first-pass complete recanalization.Disclosure of InterestMR received research funding from Medtronic andVesalioMR declares ownership of Anaconda Biomed and Methinks shares. MR received consulting fees from Anaconda Biomed, Apta Targets, Medtronic, Stryker,Cerenovus, and Philips. AT reports receiving consulting fees from Anaconda Biomed,Balt, Medtronic, MicroVention, Cerus, Merlin Medical, and Stryker. J-HBReceived consu...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Li, J., Tiberi, R., Bhogal, P., Buhk, J.-H., Behme, D., Tomasello, A., Ribo, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P153/189 Economic impact of improved functional outcomes associated with the embotrap device vs. trevo retriever and solitaire revascularization device for treatment of acute ischemic stroke: an economic analysis of mastro i from a german hospital perspective
ConclusionThe use of EmboTrap in Germany may lead to reduction in short-term hospital costs, compared to Solitaire or Trevo due to improved patient functional outcomes (90-day mRS 0–2). These findings may inform evidence-based decision making when selecting a cost-efficient SR for MT.Disclosure of InterestOsama Zaidat reports consulting fees for Stryker, Medtronic, Cerenovus, and Penumbra; research grants from Stryker, Medtronic, Cerenovus, Penumbra, and Genentech; in addition, Dr Zaidat had a patent for ischemic stroke issued.Tommy Andersson is a consultant for Anaconda, Cerenovus, Neuravi and Rapid Medical, and hol...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Zaidat, O., Kabiri, M., Scheffler, S., Kottenmeier, E., Andersson, T. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P152/178 Safety and efficiency of bridging i.v. thrombolysis in M2 occlusions: a propensity-score-matched registry cohort study
ConclusionIn M2-occlusions, MT+IVT was not associated with increased risk of sICH. Patients receiving MT+IVT had lower 90d-mRS and a lower increase in mRS pre-stroke to 90d. However, probability of functional independence and rates of successful recanalization were similar compared to matched controls.Disclosure of InterestHK has financial interest in Eppdata GmbH.GT received fees as consultant and lecturer from Acandis, Alexion, Amarin, Boehringer Ingelheim, Bayer, BMS/Pfizer, Daiichii Sankyo and Portola. He serves in the board of the TEA Stroke Study and of ESO.JF is consultant for Cerenovus, Medtronic, Microvention, Pen...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Broocks, G., Bechstein, M., Faizy, T., Winkelmeier, L., Brekenfeld, C., Flottmann, F., Paula Hanning, U. M., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 2.3 ISCHEMIC - Treatment Source Type: research