Non-cardiac Chest Pain in Japan: Prevalence, Impact, and Consultation Behavior - A Population-based Study
CONCLUSIONS: The prevalence of chest pain in this sample of a Japanese general population was 5%. Among all subjects with chest pain, less than one-third consulted physicians, approximately 70% of whom were diagnosed with NCCP. Sex and both the severity and frequency of chest pain were associated with consultation behavior.PMID:37814435 | PMC:PMC10577468 | DOI:10.5056/jnm22184 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Junji Chen Tadayuki Oshima Takashi Kondo Toshihiko Tomita Hirokazu Fukui Shinichiro Shinzaki Hiroto Miwa Source Type: research

On-demand Versus Continuous Maintenance Treatment With a Proton Pump Inhibitor for Mild Gastroesophageal Reflux Disease: A Prospective Randomized Multicenter Study
CONCLUSIONS: Continuous treatment seems to be more appropriate for the initial maintenance treatment of non-erosive GERD or mild erosive esophagitis than on-demand treatment. Stepping down to on-demand treatment needs to be considered after a sufficient period of continuous treatment.PMID:37814436 | PMC:PMC10577461 | DOI:10.5056/jnm23130 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Da Hyun Jung Young Hoon Youn Hye-Kyung Jung Seung Young Kim Cheal Wung Huh Cheol Min Shin Jung-Hwan Oh Kyu Chan Huh Moo In Park Suck Chei Choi Ki Bae Kim Seon-Young Park Joong Goo Kwon Yu Kyung Cho Jung Ho Park Jeong Eun Shin Eun Jeong Gong Jae Hak Kim Su Source Type: research

Real-world Prescription Patterns and Patient Satisfaction Regarding Maintenance Therapy of Gastroesophageal Reflux Disease: An Observational, Cross-sectional, Multicenter Study
CONCLUSION: Although overall patient satisfaction did not significantly differ among the different PPI maintenance therapy modality groups, awareness of potential adverse effects was significantly different between the on-demand and continuous therapy groups.PMID:37814437 | PMC:PMC10577463 | DOI:10.5056/jnm23088 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Cheal Wung Huh Nak Hoon Son Young Hoon Youn Da Hyun Jung Min Kyung Kim Eun Jeong Gong Kyu Chan Huh Seung Young Kim Moo In Park Ju Yup Lee Joong Goo Kwon Jae Hak Kim Cheol Min Shin Kee Wook Jung Su Jin Hong Hee Man Kim Suck Chei Choi Hye-Kyung Jung Hyun Ji Source Type: research

Spot Hydrogen Breath Test for Predicting Response to Low Fermentable Oligo-, Di-, Mono-saccharides, and Polyols Dietary Advice in Patients With Bloating
CONCLUSIONS: A higher baseline breath hydrogen level was associated with bloating improvement after low FODMAPs dietary advice. A spot breath test after lunch, a simple point-of-care test, is possibly helpful in managing patients with bloating.PMID:37814438 | PMC:PMC10577458 | DOI:10.5056/jnm22214 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Pochara Somvanapanich Panyavee Pitisuttithum Jarongkorn Sirimongkolkasem Pakkapon Rattanachaisit Sureeporn Jangsirikul Tanisa Patcharatrakul Sutep Gonlachanvit Source Type: research

Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats
CONCLUSIONS: Berberine enriched Lachnoclostridium, reduced the expression of peptidoglycan biosynthesis genes and increased acetate and propionate. The absence of these actions of rifaximin may explain the different effects of the drugs on microbiota-gut-brain axis.PMID:37814439 | PMC:PMC10577460 | DOI:10.5056/jnm22182 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Jindong Zhang Cunzheng Zhang Tao Zhang Lu Zhang Liping Duan Source Type: research