Thinning of the Skull Base and Calvarial Thickness in Patients With Idiopathic Intracranial Hypertension
Background: Idiopathic intracranial hypertension (IIH) is a disorder characterized by elevated intracranial pressure without secondary causes on neuroimaging. IIH typically occurs in young, obese female patients and, when severe, can cause permanent and irreversible vision loss. The association between skull base thinning in patients with intracranial hypertension and obesity has been previously reported; however, no study has reported these findings in IIH. The goal of our study is to determine whether IIH is independently associated with skull base and calvarial thinning. Methods: A retrospective, matched case...
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research

Idiopathic Intracranial Hypertension: Incidental Discovery Versus Symptomatic Presentation
Background: We aim to compare the clinical characteristics, disease course and visual outcomes between Canadian patients with idiopathic intracranial hypertension (IIH) who were incidentally discovered and those who sought care due to symptoms of IIH. Methods: Retrospective chart review of consecutive IIH patients conducted at tertiary neuro-ophthalmology clinics. Patients were divided into Group 1 (incidentally discovered disease) and Group 2 (patients seeking medical care due to symptoms of intracranial hypertension). Results: One hundred eighty-six patients were included in the study; of which, 75 (40....
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research

Patient Personality and Illness Perceptions in Relation to Follow-Up Appointment Adherence in Neuro-Ophthalmology
Background: Improving patient attendance at medical follow-up visits may have a notable impact on disease and overall health outcomes. Understanding factors contributing to poor attendance is important for identifying at-risk patients and designing interventions to improve clinical outcomes. Our objective was to identify personality and illness perception factors associated with attendance at recommended follow-up visits in a neuro-ophthalmology practice. Methods: New or established patients (≥18 years) with scheduled neuro-ophthalmology (study) or glaucoma (comparison) appointments at a tertiary care academic...
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research

Does Tocilizumab Influence Ophthalmic Outcomes in Giant Cell Arteritis?
Conclusions: Compared with conventional corticosteroid monotherapy, treatment of GCA with both corticosteroids and tocilizumab may decrease the likelihood of permanent vision loss. Further prospective, collaborative investigation between rheumatologists and neuro-ophthalmologists is required to clarify the ophthalmic and socioeconomic impact of tocilizumab on the treatment of GCA. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Mechanisms of Entry Into the Central Nervous System by Neuroinvasive Pathogens
Conclusions: Although there is a paucity of data supporting direct viral entry of SARS-CoV-2 in humans, increasing our knowledge of the structural components of CNS compartments that block viral entry and pathways exploited by pathogens is fundamental to preparing clinicians and researchers for what to expect when a novel emerging virus with neurological symptoms establishes infection in the CNS, and how to design therapeutics to mitigate such an infection. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Neuro-Ophthalmological Complications of the COVID-19 Vaccines: A Systematic Review
Conclusion: Since the implementation of the COVID-19 vaccination campaign in the past year, several post-COVID-vaccination neuro-ophthalmological complications have been described. However, considering the number of individuals that have been exposed to the vaccines, the risk seems very low, and the clinical outcome in most cases is favorable. Therefore, on a population level, the benefits of the vaccines far outweigh the risk of neuro-ophthalmological complications. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Disease of the Year 2021 Encore: COVID-19 Source Type: research

Dominant Optic Atrophy: How to Determine the Pathogenicity of Novel Variants?
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Perspective Source Type: research

Clinical Machine Learning Modeling Studies: Methodology and Data Reporting
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 27, 2022 Category: Opthalmology Tags: Editorial Source Type: research

Intractable Headache and Vomiting in a Pediatric Patient
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: UPFRONT Case Source Type: research

Acute Onset of Diplopia in an Uncontrolled Diabetic
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: UPFRONT Case Source Type: research

Postoperative Vision Loss
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: UPFRONT Cases Source Type: research

American Academy of Ophthalmology Annual Meeting 2021
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

Scottsdale Headache Symposium 2021
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

Postcataract Surgery Anterior Ischemic Optic Neuropathy
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Papilledema and Extensive Dural Sinus Thrombosis Due to JAK2 Mutation: Response
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Letters to the Editor Source Type: research