Comparison of Visual Evoked Potentials in Patients Affected by Optic Neuritis From Multiple Sclerosis or Neuromyelitis Optica Spectrum Disorder
Conclusions:
ON-MS eyes had normal amplitude and delayed VEP latency, whereas ON-NMOSD eyes displayed reduced amplitude and preserved latency when elicited by checkerboard stimulus with large 1.5° checks. Under such conditions, VEP may help distinguish resolved MS-related ON from resolved NMOSD-related ON. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Visual Function and Brief Cognitive Assessment for Multiple Sclerosis in Optic Neuritis Clinically Isolated Syndrome Patients
Conclusion:
Cognitive testing, assessed binocularly, of visuospatial processing is affected after unilateral optic neuritis and improves over time with visual recovery. This is not related to structural markers of the visual or central nervous system. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Optical Coherence Tomography Is Associated With Cognitive Impairment in Multiple Sclerosis
Conclusion:
OCT measurements correlate with cognitive performance in MS patients. OCT can thus be used to evaluate central nervous system neurodegeneration in MS, as reflected by cognitive decline. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Cognitive Performance of Patients With Multiple Sclerosis and Optic Neuritis at Presentation
Background:
Cognitive dysfunction is common among patients with multiple sclerosis (MS), but the effect of coexisting optic neuritis (ON) at the first presentation of multiple sclerosis on the course of cognitive decline is unknown. The purpose of this study was to assess whether ON at presentation has any effect on the progression of cognitive decline in MS.
Methods:
Historical cohort study. We retrospectively compared the cognitive performance of patients with relapsing-remitting MS with and without ON at the time of MS diagnosis. Subjects were included if cognitive test results were available both at baseline...
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Characterization and Utility of Remote Interpretation of Visual Field Diagnostic Testing in an Academic Center
Conclusions:
Remote interpretation of VFs was most often requested by endocrinology, neurology, and neurosurgery and could be performed very quickly. The most common indications were parasellar lesions, and just less than half of patients receiving remote VF interpretations had a prior intervention. A majority of remote VF interpretations were able to answer the clinical question, given the patient's clinical history and imaging. Remote interpretation of VFs may thus offer referring departments a more efficient method of obtaining VF interpretations than in-office neuro-ophthalmology examinations. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Jane C. Sargent, MD (1944–2021)
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: In Memoriam Source Type: research
Great Conversation With Dr. John Keltner
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Great Conversations Source Type: research
Great Conversation With Susan Carlow
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Great Conversations Source Type: research
Is Neuroretinitis Associated With Multiple Sclerosis?
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Point Counter-Point Source Type: research
Misdiagnosis of Third Nerve Palsy
Conclusions:
Misdiagnosis of 3rd nerve palsy was common. Performance and interpretation of the physical examination were the most common factors leading to misdiagnosis of 3rd nerve palsy. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
The “Eyelet Sign” as an MRI Clue for Inflammatory Brown Syndrome
Conclusions:
Both in children and in adults, MRI can provide evidence of inflammatory changes located at the trochlea–tendon complex in acquired Brown syndrome here referred to as the “eyelet sign,” which may be helpful in confirming the clinical diagnosis and guide appropriate treatment. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Cavernous Malformation of the Optic Nerve and Chiasm: Prompt Suspicion and Surgery Matter
Conclusion:
MRI features are critical to the diagnosis of optic nerve and chiasm CM and may mimic other lesions. A high index of suspicion by the neuro-ophthalmologist and neuroradiologist leads to early recognition and intervention. Given optic CM displaces and does not infiltrate neural tissue, expedited surgical resection by a neurosurgeon after consideration of other diagnostic possibilities improves visual function in most cases. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Correlation Between Ophthalmologic and Neuroradiologic Findings in Type 1 Neurofibromatosis
Conclusions:
This study suggests that focal choroidal abnormalities are correlated with the presence of CNS lesions as OPGs in patients with NF-1, and it might be a surrogate for the need for CNS imaging in these patients. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
The Effect of Optic Nerve Sheath Fenestration on Intraocular Pressure in Patients With Idiopathic Intracranial Hypertension
Conclusions:
Reducing the cerebral spinal fluid pressure (CSFP) at the level of the intraorbital optic nerve through an ONSF can slightly reduce the IOP. In those with evidence of posterior globe or scleral indentation/flattening, the reduction in IOP was higher, which supports the theory that CSF pressure indents the globe and leads to an increase in IOP. Although these changes in IOP are small, this study provides further evidence for a connection between IOP and CSFP. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
Development of a Prognostic Model for Predicting Multiple Sclerosis After Optic Neuritis: A Secondary Analysis of Data From the Optic Neuritis Treatment Trial
Background:
Optic neuritis can be the initial manifestation of multiple sclerosis (MS). The purpose of this study was to develop a prognostic model for predicting the risk of MS development among patients with optic neuritis.
Methods:
The data from 388 patients with optic neuritis were retrieved from the Optic Neuritis Treatment Trial (ONTT). Cox proportional hazards regression analysis was used to develop a prognostic model. The performance of the model was assessed by using Harrell's C-index and calibration curves. The rates of MS development were estimated using the Kaplan–Meier method.
Results:
Amon...
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research
