The impact of the COVID-19 pandemic on the mental health of patients diagnosed with inflammatory bowel diseases
In conclusion, the emergence of a novel viral pathogen represents a significant distress factor for patients with autoimmune diseases. Recognizing and comprehending these consequences enhances our understanding of the intricate interplay between physical and mental health and equips authorities with valuable insights to better manage future epidemics or viral outbreaks. This study underscores the importance of tailored support systems and strategies for patients with autoimmune diseases during global health crises.PMID:38585531 | PMC:PMC10994603 | DOI:10.25122/jml-2023-0475 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Oliviu-Florentiu Sarb Vitalie Vacaras Vladimir-Petru Filip Adriana-Daniela Sarb Roxana-Delia Zaharie Nicu Draghici Dafin-Fior Muresanu Alina-Ioana Tantau Source Type: research
Evaluating the renoprotective effects of omega-3-6-9 against cisplatin-induced nephrotoxicity in mice
This study explored the renoprotective potential of omega-3-6-9 when co-administered with cisplatin in a mice model. We divided adult mice into five groups: a control group received 0.5 ml of liquid paraffin; a cisplatin-only group; two groups were treated with low (50 mg/kg) and high (100 mg/kg) doses of omega-3-6-9 plus cisplatin; and a final group received vitamin E before cisplatin administration. The administration of omega-3-6-9 significantly decreased pro-inflammatory modulators and kidney function markers such as TNF-α, IL-1β, blood urea nitrogen, and creatinine, indicating potential renoprotective effects. Our r...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Saja Kareem Abd Alhusen Ali Faris Hasan Source Type: research
Assessment of manometric results following posterior pericervical repair or level I to III surgical procedures
This study aimed to evaluate the manometry results of patients before and after reconstructive surgery of the posterior compartment. This retrospective cohort study included 40 women with defecation disorders referred to the Imam Khomeini Hospital Complex, an academic center affiliated with Tehran University of Medical Sciences, Tehran, Iran, from 2020 to 2021. Data were collected through medical records and a checklist developed by the researcher before and after surgery. All analyses were performed using SPSS software (version 26), with significance at p<0.05. Forty women with a mean age of 49.47±9.66 years participa...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Maryam Deldar Pesikhani Reihane Sadat Hosseini Sanam Ghanbarpour Sanaz Ghashghaee Parivash Jelodarian Maryam Kazemi Tahereh Eftekhar Zinat Ghanbari Source Type: research
Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients
This study assessed the therapeutic response of chronic obstructive pulmonary disease (COPD) patients by measuring oxidative superoxide dismutase (SOD3), glutathione peroxidase 1 (GPX1), and inflammatory biomarkers such as tumor necrosis factor-alpha (TNF-α) and Interleukin-8 (IL-8) after sublingual administration of glutathione supplements. A cohort of 50 COPD individuals was involved and divided into two groups of 25 each. The first group received conventional therapy involving the administration of formoterol fumarate (12 µg inhaler) twice daily. The second group received the conventional treatment alongside sublingua...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Ali Farag Wassan Abass Hyder Qassem Source Type: research
Valsalva purpura on the face of a 7-year-old child
This article overviews the relationship between the Valsalva maneuver, purpura, and similar cases.PMID:38585535 | PMC:PMC10994611 | DOI:10.25122/jml-2023-0447 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Alia Ali Galadari Moteb Al Otaibi Source Type: research
Exploring female medical students' knowledge, attitudes, practices, and perceptions related to breast cancer screening: a scoping review
J Med Life. 2023 Dec;16(12):1732-1739. doi: 10.25122/jml-2023-0412.ABSTRACTEarly detection measures for breast cancer, such as breast self-exams, clinical breast exams, and mammography, have considerable benefits in effectively reducing breast cancer-related mortality. As the incidence of breast cancer is steadily increasing, it is crucial to raise awareness on early detection. This scoping review assessed the current knowledge, attitudes, practices, and perceptions of breast cancer screening among female medical students. We used the six phases of Arksey and O'Malley's framework from the Joanna Briggs Institute Manual and...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Mirela Tomic Maria-Lorena Vescan Marius-Ionu ţ Ungureanu Source Type: research
Comparative analysis of immunological biomarkers in COVID-19 and bacterial pneumonia
This study highlights the potential significant impact of COVID-19 on the immunological biomarkers investigated.PMID:38585537 | PMC:PMC10994609 | DOI:10.25122/jml-2023-0273 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Mudathir Abdelshafea Abdelkareem Abakar Daralnaeem Hassan Ali Hamad Eman Faisal Hashim Mohamed Fad-Alla Omer Mahmoud Taha Mohamed Faki Abdellla Esmail Mohammed Idris Rouwida Omer Zeinab Osman Entesar Ahmed Gaffar Elhassan Mohamed Ahmed Abrahim-Holie Moham Source Type: research
Learning style preference and the academic achievements of medical students in an integrated curriculum
J Med Life. 2023 Dec;16(12):1802-1807. doi: 10.25122/jml-2023-0366.ABSTRACTUnderstanding how individuals learn best, known as learning style, is integral to optimizing educational outcomes. This analytical study was conducted among students in their fourth year who finalized their problem-based activities at the College of Medicine, University of Bisha, Saudi Arabia. The visual, aural, read/write, and kinesthetic (VARK) model was adopted to assess individual differences in learning preferences and their correlation with academic achievement in the problem-based learning (PBL)-dependent curriculum. The online self-administe...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Adel Mohamed Aboregela Source Type: research
Morphology and thickness of corneal endothelial cells in young Sudanese individuals with myopia
This study aimed to evaluate corneal endothelial cell morphology and central corneal thickness in young individuals with myopia. A prospective study was conducted at Al-Neelain University Eye Hospital between January 2019 and January 2020, including 160 patients with myopia (320 eyes). Data was gathered through clinical assessment of visual acuity, refractive error, and corneal endothelial cells. Results showed that 60% of participants with myopia were female, with a mean age of 21.99±2.8 years and a mean equivalent sphere of -3.19±2.67D. There was a significant difference in endothelial cell degeneration between myopia ...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Raghda Faisal Mutwaly Saif Hassan Alrasheed Abd Elaziz Mohamed Elmadina Sulaiman Aldakhil Source Type: research
Efficacy and safety of physical therapy in patients with stage III COPD during ambulatory rehabilitation
This study aimed to determine the efficacy of a combined physical therapy and pharmacological treatment for patients recovering from stage III COPD exacerbation. The efficacy of the rehabilitation program was assessed using anthropological parameters, physical condition, respiratory system function, and functional endurance capacity. Data were collected from 39 patients with stage III COPD who underwent the rehabilitation program. Physical and anthropometric assessments were conducted using the Quetelet Body Mass Index, the Pignet Index, and the Vital Capacity Index (VCI). The functional capacities of the cardiorespiratory...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Ulyana Kuz Svitlana Maliuvanchuk Roman Herych Petro Herych Source Type: research
Azilsartan improves doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, proinflammatory pathway, and apoptosis
This study investigated whether azilsartan could mitigate doxorubicin-induced cardiotoxicity. We divided 28 male rats into four groups: the control group receiving a standard diet and water, the vehicle group given DMSO orally for two weeks, doxorubicin group receiving 2.5 mg/kg of doxorubicin three times a week for two weeks, and azilsartan group treated with 5 mg/kg/day of azilsartan orally and doxorubicin. Doxorubicin-induced cardiotoxicity was evidenced by a significant increase in TNF-α, IL-1β, MDA, and caspase-3 levels and significantly decreased TAC and Bcl-2 levels in the cardiac tissues of treated rats compared ...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Mohammed Al-Chlaihawi Ali Janabi Source Type: research
Add-on treatment with Cerebrolysin improves clinical symptoms in patients with ALS: results from a prospective, single-center, placebo-controlled, randomized, double-blind, phase II study
J Med Life. 2023 Dec;16(12):1750-1755. doi: 10.25122/jml-2023-0459.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a devastating and progressive neurodegenerative disease with limited treatment options available. Cerebrolysin is a drug candidate for the treatment of ALS because of its neuroprotective and neuroregenerative effects. We initiated a pilot clinical study of a combination of Cerebrolysin and riluzole to assess the therapeutic benefit of Cerebrolysin as an add-on treatment on clinical signs and symptoms in outpatients with ALS. Twenty patients with a clinically definitive diagnosis of ALS were enrolled and randoml...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Alfredo Jos é Firstenfeld Jorge Listorti Nasser Jalaff Claudia Patricia Loaiza Orozco Francisco Navarrete Gosdenovich Timo Schurr Source Type: research
Unveiling the Future of Neurorehabilitation: Insights from the 18 < sup > th < /sup > Congress from the Society for the Study of Neuroprotection and Neuroplasticity (SSNN) in Conjunction with the WFNR-EFNR Central Asia Regional Meeting
J Med Life. 2023 Dec;16(12):1717-1722. doi: 10.25122/jml-2023-1033.NO ABSTRACTPMID:38585518 | PMC:PMC10994616 | DOI:10.25122/jml-2023-1033 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Stefana-Andrada Dobran Alexandra Gherman Dafin Mure şanu Source Type: research
Insights into Swallowing Disorders: the Dysphagia Course Series
J Med Life. 2023 Dec;16(12):1714-1716. doi: 10.25122/jml-2023-1032.NO ABSTRACTPMID:38585519 | PMC:PMC10994618 | DOI:10.25122/jml-2023-1032 (Source: Journal of Medicine and Life)
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Stefana-Andrada Dobran Alexandra Gherman Dafin Muresanu Source Type: research
Disability inclusion assessment in primary healthcare centers in Eastern Saudi Arabia: a way forward
This study aimed to identify challenges related to accessibility in infrastructure, services, equipment, processes, and training in primary healthcare settings. The study was conducted in Dammam, AlKhobar, and AlQatif in August 2022, using an analytical, quantitative cross-sectional approach. A total of 56 primary healthcare centers (PHCs) were assessed across multiple domains. Government-built PHCs had an average accessibility rate of 83.2%, while those located in rented buildings scored an average of 67.1%. One domain that scored highly among both building types was the clinic rooms domain, with an average score of 90%. ...
Source: Journal of Medicine and Life - April 8, 2024 Category: General Medicine Authors: Lamees Yousef Norah Almatroodi Dannah AlAngari Rahaf AlShehri Shahad Alshammari Source Type: research
