[ASAP] Reduction of the Renal Radioactivity of < sup > 111 < /sup > In-DOTA-Labeled Antibody Fragments with a Linkage Cleaved by the Renal Brush Border Membrane Enzymes
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00258 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 16, 2023 Category: Chemistry Authors: Hiroyuki Suzuki, Mari Araki, Kouki Tatsugi, Kento Ichinohe, Tomoya Uehara, and Yasushi Arano Source Type: research
[ASAP] Developing a Multitargeted Anticancer Palladium(II) Agent Based on the His-242 Residue in the IIA Subdomain of Human Serum Albumin
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00248 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 15, 2023 Category: Chemistry Authors: Wenjuan Li, Shanhe Li, Zhenlei Zhang, Gang Xu, Xueyu Man, Feng Yang, and Hong Liang Source Type: research
[ASAP] Development and Characterization of Potent Succinate Receptor Fluorescent Tracers
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00552 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 15, 2023 Category: Chemistry Authors: Marija Ciba, Bethany Dibnah, Brian D. Hudson, and Elisabeth Rexen Ulven Source Type: research
[ASAP] Topology-Based and Conformation-Based Decoys Database: An Unbiased Online Database for Training and Benchmarking Machine-Learning Scoring Functions
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00801 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 15, 2023 Category: Chemistry Authors: Xujun Zhang, Chao Shen, Tianyue Wang, Yu Kang, Dan Li, Peichen Pan, Jike Wang, Gaoang Wang, Yafeng Deng, Lei Xu, Dongsheng Cao, Tingjun Hou, and Zhe Wang Source Type: research
[ASAP] Recent Advances in Pro-PROTAC Development to Address On-Target Off-Tumor Toxicity
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00302 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 15, 2023 Category: Chemistry Authors: Chuanjie Chen, Yiwen Yang, Zhe Wang, Huiwen Li, Chanjuan Dong, and Xuan Zhang Source Type: research
[ASAP] First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00720 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 14, 2023 Category: Chemistry Authors: Avinash H. Bansode, Naresh Damuka, Nagaraju Bashetti, Krishna Kumar Gollapelli, Ivan Krizan, Bhuvanachandra Bhoopal, Mack Miller, Shanmukha Kumar JV, Christopher T. Whitlow, Donald McClain, Tao Ma, Matthew J. Jorgensen, and Kiran Kumar Solingapuram Sai Source Type: research
[ASAP] Chromatography-Free Synthesis of β < italic toggle="yes" > - < /italic > Carboline 1 ‑Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of β < italic toggle="yes" > - < /italic > Carbolines as Promising Antifungal and Antibacterial Candidates
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00650 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 14, 2023 Category: Chemistry Authors: Tao Sheng, Chenjie Yu, Yujie Wang, Shengkun Li, Huijun Wu, Qin Gu, Guangrong Meng, Alastair N. Herron, and Xuewen Gao Source Type: research
[ASAP] Design and Pharmacological Chaperone Effects of < italic toggle="yes" > N < /italic > ‑(4′-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α‑Glucosidase
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00637 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 14, 2023 Category: Chemistry Authors: Atsushi Kato, Izumi Nakagome, Maki Kise, Kousuke Yoshimura, Nobutada Tanaka, Robert J. Nash, George W. J. Fleet, Yota Kobayashi, Hayato Ikeda, Takuya Okada, and Naoki Toyooka Source Type: research
[ASAP] Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00519 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 14, 2023 Category: Chemistry Authors: Heeren M. Gordhan, Steven T. Miller, Daphne C. Clancy, Maria Ina, Alan V. McDougal, D ’Quan K. Cutno, Robert V. Brown, Cynthia L. Lichorowic, Jill M. Sturdivant, Kyle A. Vick, Stuart S. Williams, Mitchell A. deLong, Jeffrey C. White, Casey C. Kopczynski Source Type: research
[ASAP] Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant < italic toggle="yes" > Enterococcus < /italic >
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00633 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 14, 2023 Category: Chemistry Authors: Kalinka Koteva, Min Xu, Wenliang Wang, Aline A. Fiebig-Comyn, Michael A. Cook, Brian K. Coombes, and Gerard D. Wright Source Type: research
[ASAP] Design and Synthesis of 4 ‑Fluorophenyl-5-methylene-2(5 < italic toggle="yes" > H < /italic > ) ‑furanone Derivatives as Potent Quorum Sensing Inhibitors
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.2c01866 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 13, 2023 Category: Chemistry Authors: Panpan Zhang, Weijin Chen, Yang-Chun Ma, Bingfang Bai, Guanglin Sun, Shenyan Zhang, Xiaohong Chang, Yingmei Wang, Nan Jiang, Xianghui Zhang, and Shutao Ma Source Type: research
[ASAP] Creating Pyrethrin Mimetic Phosphonates as Chemical Genetics Tools Targeting the GDSL Esterase/Lipase TcGLIP to Investigate Pyrethrin Biosynthesis
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00285 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 13, 2023 Category: Chemistry Authors: Noritada Matsuo, Yukimi Sugisaka, Shiori Aoyama, Makoto Ihara, Harue Shinoyama, Munetaka Hosokawa, Yoshinobu Kamakura, Daisuke Tanaka, Yoo Tanabe, and Kazuhiko Matsuda Source Type: research
[ASAP] < italic toggle="yes" > In Vitro < /italic > and < italic toggle="yes" > In Vivo < /italic > Biological Activities of Dipicolinate Oxovanadium(IV) Complexes
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00255 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 13, 2023 Category: Chemistry Authors: Katarzyna Choroba, Beatriz Filipe, Anna S ́witlicka, Mateusz Penkala, Barbara Machura, Alina Bieńko, Sandra Cordeiro, Pedro V. Baptista, and Alexandra R. Fernandes Source Type: research
[ASAP] Discovery and Structure-Based Design of Inhibitors of the WD Repeat-Containing Protein 5 (WDR5) –MYC Interaction
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00787 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 12, 2023 Category: Chemistry Authors: Jian Ding, Lulu Liu, Ying-Ling Chiang, Mengxi Zhao, Hejun Liu, Fei Yang, Lingling Shen, Ying Lin, Huiwen Deng, Jingyan Gao, David R. Sage, Laura West, Luis A. Llamas, Xin Hao, Sameer Kawatkar, En Li, Rishi K. Jain, John A. Tallarico, Stephen M. Canham, an Source Type: research
[ASAP] Structure –Activity Relationships of Bis-Intercalating Peptides and Their Application as Antibody–Drug Conjugate Payloads
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00760 (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - June 12, 2023 Category: Chemistry Authors: Mark E. Petersen, Michael G. Brant, Manuel Lasalle, Vincent K. C. Fung, Andrea Hernandez Rojas, Jodi Wong, Samir Das, Stuart D. Barnscher, Jamie R. Rich, and Geoffrey C. Winters Source Type: research
