Registry-based assessment of the status of cervical screening in Sweden
Conclusions Registry-based analyses of key quality indicators provided the basis for prioritizing improvements of the organized cervical screening programme. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Elfström, K. M., Sparen, P., Olausson, P., Almstedt, P., Strander, B., Dillner, J. Tags: Original Articles Source Type: research

The role of pre-invasive disease in overdiagnosis: A microsimulation study comparing mass screening for breast cancer and cervical cancer
Conclusions For breast cancer, the frequency of overdiagnosis in screening is relatively low, but consequences are evident. For cervical cancer, the frequency of overdiagnosis in screening is high, because of detection of pre-invasive disease, but the consequences per case are relatively small due to less invasive treatment. This illustrates that it is necessary to present overdiagnosis in relation to disease stage and consequences. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: van Luijt, P. A., Rozemeijer, K., Naber, S. K., Heijnsdijk, E. A., van Rosmalen, J., van Ballegooijen, M., de Koning, H. J. Tags: Original Articles Source Type: research

Balancing the benefits and detriments among women targeted by the Norwegian Breast Cancer Screening Program
Conclusion The benefit–detriment ratio estimates of the Norwegian Breast Cancer Screening Program, expressed as lives saved from breast cancer death and epidemiologic over-diagnosis, should be interpreted with care due to substantial uncertainties in the estimates, and the differences in the scale of values of the events compared. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Hofvind, S., Roman, M., Sebuodegard, S., Falk, R. S. Tags: Original Articles Source Type: research

Estimation of overdiagnosis using short-term trends and lead time estimates uncontaminated by overdiagnosed cases: Results from the Norwegian Breast Screening Programme
Conclusion Using short-term trends, instead of long, prior to screening was more effective in predicting incidence in the screening epoch. In addition, sojourn time estimation using symptomatic cancers only avoids over-correction for lead time and consequently underestimation of overdiagnosis. Longer follow-up will provide more precise estimates of overdiagnosis. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Michalopoulos, D., Duffy, S. W. Tags: Original Articles Source Type: research

Ambient temperature and FIT performance in the Emilia-Romagna colorectal cancer screening programme
Conclusions Ambient temperatures can affect screening performance. Continued monitoring is needed to verify the effect of introducing FIT tubes with a new buffer, which should guarantee a higher stability of haemoglobin. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: De Girolamo, G., Goldoni, C. A., Corradini, R., Giuliani, O., Falcini, F., Sassoli DeBianchi, P., Naldoni, C., Zauli Sajani, S. Tags: Original Articles Source Type: research

Defining and measuring adherence to cancer screening
Conclusion We conclude that consistent definitions and estimation of adherence to cancer screening guidelines will facilitate comparison across studies, tests, and settings, and help to elucidate areas for future research and intervention. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Chubak, J., Hubbard, R. Tags: Original Articles Source Type: research

Newborn screening for sickling and other haemoglobin disorders using tandem mass spectrometry: A pilot study of methodology in laboratories in England
Conclusions This multicentre study demonstrates that it is possible to implement mass spectrometry–mass spectrometry into an established screening programme while maintaining consistency with existing methods for haemoglobinopathy screening. However, one of the instruments investigated cannot be recommended for use with this application. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Daniel, Y. A., Henthorn, J. Tags: Original Articles Source Type: research

Antenatal reflex DNA screening for trisomy 18 and trisomy 13 in addition to Downs syndrome
Conclusion Reflex DNA screening for trisomies 18 and 13 can be usefully added to reflex DNA screening for Down’s syndrome. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 3, 2016 Category: Epidemiology Authors: Bestwick, J. P., Wald, N. J. Tags: Original Articles Source Type: research

HPV self-sampling in Japanese women: A feasibility study in a population with limited experience of tampon use
Conclusions Self-sampling was highly acceptable in this population of women. They could perform the test safely unsupervised, but lacked confidence the test has been carried out correctly. Japanese women need to be educated about the accuracy of human papillomavirus self-sampling and further large-scale studies are necessary in non-responders. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Hanley, S. J., Fujita, H., Yokoyama, S., Kunisawa, S., Tamakoshi, A., Dong, P., Kobayashi, N., Watari, H., Kudo, M., Sakuragi, N. Tags: Original Articles Source Type: research

Effectiveness of timed and non-timed second appointments in improving uptake in breast cancer screening
Conclusions Second timed appointments were almost three times as effective as additional open invitation. They should be targeted at women most likely to attend. A randomized study of second timed appointments versus open invitations should be conducted. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Hudson, S., Brazil, D., Teh, W., Duffy, S. W., Myles, J. P. Tags: Original Articles Source Type: research

Audit feedback on reading performance of screening mammograms: An international comparison
Conclusion The purpose, target audience, performance measures included, form and frequency of the audit feedback varied amongst mammographic screening programmes. These variations may provide a basis for those developing and improving such programmes. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Hofvind, S., Bennett, R., Brisson, J., Lee, W., Pelletier, E., Flugelman, A., Geller, B. Tags: Original Articles Source Type: research

A pilot randomized controlled trial of telephone intervention to increase Breast Cancer Screening uptake in socially deprived areas in Scotland (TELBRECS)
Conclusions A simple telephone reminder doubled attendance at breast screening in women from lower socio-demographic areas who had not attended their initial appointment, compared with a reminder letter only (odds ratio 2.12, 95% CI (1.2, 3.8)). However, contacting women proved problematic and there was no additional effect of telephone support or anticipated regret. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Chambers, J. A., Gracie, K., Millar, R., Cavanagh, J., Archibald, D., Cook, A., OCarroll, R. E. Tags: Original Articles Source Type: research

Complications after colonoscopy and surgery in a population-based colorectal cancer screening programme
Conclusions Overall complication rates were acceptable and mortality low; however, the rate of anastomotic leakage after surgery for both adenomas and CRC was higher than expected. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Saraste, D., Martling, A., Nilsson, P. J., Blom, J., Törnberg, S., Hultcrantz, R., Janson, M. Tags: Original Articles Source Type: research

Interval cancers using a quantitative faecal immunochemical test (FIT) for haemoglobin when colonoscopy capacity is limited
Conclusions The IC proportion was similar to that seen with guaiac-based FOBT. The later stage distribution of ICs highlights the benefits of lower f-Hb cut-offs, but with 19.4% of ICs having undetectable f-Hb, some cancers would have been missed, even with drastic reduction in the f-Hb cut-off. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Digby, J., Fraser, C. G., Carey, F. A., Lang, J., Stanners, G., Steele, R. J. Tags: Original Articles Source Type: research

Inborn errors of metabolism detectable by tandem mass spectrometry in Egypt: The first newborn screening pilot study
Conclusions Egypt has one of the highest reported birth prevalence rates for metabolic disorders detectable by tandem mass spectrometry. Early diagnosis and management are crucial for the survival and well-being of affected children. A nationwide NBS programme by tandem mass spectrometry is recommended. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 7, 2016 Category: Epidemiology Authors: Hassan, F. A., El-Mougy, F., Sharaf, S. A., Mandour, I., Morgan, M. F., Selim, L. A., Hassan, S. A., Salem, F., Oraby, A., Girgis, M. Y., Mahmoud, I. G., El-Badawy, A., El-Nekhely, I., Moharam, N., Mehaney, D. A., Elmonem, M. A. Tags: Original Articles Source Type: research