In vitro antidermatophytic activity and cytotoxicity of extracts derived from medicinal plants and marine algae
ConclusionsThe medicinal plant extracts exhibited stronger antidermatophytic activity compared to the algae extracts. The leaves of R. excelsa and S. myrtifolium are potential sources of new antidermatophytic agents against Trichophyton spp. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 28, 2018 Category: Biology Source Type: research
Statistical versus artificial intelligence -based modeling for the optimization of antifungal activity against Fusarium oxysporum using Streptomyces sp. strain TN71
Publication date: Available online 26 July 2018Source: Journal de Mycologie MédicaleAuthor(s): S. Smaoui, K. Ennouri, A. Chakchouk-Mtibaa, I. Sellem, K. Bouchaala, I. Karray-Rebai, L. MellouliAbstractA Streptomyces sp. strain TN71 was isolated from Tunisian Saharan soil and selected for its antimicrobial activity against phytopathogenic fungi. In an attempt to increase its anti–Fusarium oxysporum activity, GYM + S (glucose, yeast extract, malt extract and starch) culture medium was selected out of five different production media. Plackett–Burman design (PBD) was used to select yeast extract, malt extract and...
Source: Journal of Medical Mycology - July 27, 2018 Category: Biology Source Type: research
In vitro activity of antifungal combinations against planktonic and sessile cells of Candida albicans isolated from medical devices in an intensive care department
ConclusionThe obtained results showed that the combination of amphotericin B with either caspofungin or voriconazole can be used as a new strategy for management of systemic mycoses associated to medical devices. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 19, 2018 Category: Biology Source Type: research
Candida auris: An emerging drug resistant yeast – A mini-review
Publication date: Available online 17 July 2018Source: Journal de Mycologie MédicaleAuthor(s): A.L. Bidaud, A. Chowdhary, E. DannaouiAbstractCandida auris is an emerging fungal pathogen responsible for nosocomial invasive infection outbreaks on five continents. Large healthcare-related outbreaks of C. auris infection and colonization have been reported from different countries. Whole genome sequence analysis identified strong phylogeographic C. auris clades specific to particular geographical areas suggesting transmission of particular clades within countries. However, the mode of transmission within the healthcare envi...
Source: Journal of Medical Mycology - July 18, 2018 Category: Biology Source Type: research
Environmental and molecular study of fungal flora in asthmatic patients
Publication date: March 2018Source: Journal de Mycologie Médicale, Volume 28, Issue 1Author(s): H. Trablesi, I. Hadrich, S. Neji, N. Fendri, D. Ghorbel, F. Makni, H. Ayadi, S. Kammoun, A. AyadiSummaryThe aim of the present study was to investigate the epidemiological and fungal environmental profile in asthmatic patients. We conducted a prospective study involving 49 patients with allergic asthma. One hundred and forty-five clinical samples and 289 environmental samples were performed. Only 30 patients accepted to participate to the environmental study at their home. For specific IgE antibodies, ELISA assay was conducted ...
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
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Publication date: March 2018Source: Journal de Mycologie Médicale, Volume 28, Issue 1Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Les intertrigos interorteils impliquant Fusarium spp. à Dakar (Sénégal)
ConclusionL’IIO à Fusarium chez un sujet sain nécessite une surveillance régulière car toute diminution ultérieure des défenses immunitaires pourrait entraîner une dissémination hématogène mortelle.SummaryIntroductionFungal interdigital tinea pedis (ITP) is a common pathology mainly due to dermatophytes and yeasts. Fusarium sp. is rarely incriminated in the genesis of intertrigo. In Dakar, a recent study conducted in 2016 on fungal ITP showed that Fusarium were more involved in the etiology of ITP than dermatophytes, coming just after yeasts dominated by Candida. Following this, we wanted to draw attention to t...
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Analysis on clinical characteristics and drug resistance of Candida parapsilosis bloodstream infections in West China Hospital, China, from 2012 to 2015
ConclusionIn summary, elders and newborns were more vulnerable to C. parapsilosis infections. C. parapsilosis was found frequently as pathogens leading to BSI in patients admitted to ICU and departments of surgery and often causing a high mortality rate. C. parapsilosis rarely showed drug resistance at present, so common antifungal drugs could be used for treatment. Recommendations for using of antifungal drugs focused on paying close attention to possible drug resistance trend. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Saccharomyces cerevisiae fungemia after probiotic treatment in an intensive care unit patient
We present two fungemia cases in an intensive care unit following probiotic treatment containing S. boulardii. We are warning the safety of probiotic treatment in critically ill patients. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Une ulcération cutanée due à Rhodotorula mucilaginosa chez un enfant immunodéprimé
Publication date: March 2018Source: Journal de Mycologie Médicale, Volume 28, Issue 1Author(s): H. Tligui, W. Oudaina, S. El Ftouh, F. Madda, L. HesseissenRésuméLes infections cutanées humaines dues à Rhodotorula spp. sont rarement décrites dans la littérature. Cet agent pathogène émergent est responsable d’affections cutanées aussi bien chez l’immunocompétent que l’immunodéprimé. Dans le présent cas, une infection cutanée due à Rhodotorula mucilaginosa était décrite chez un enfant ayant un rétinoblastome. Le diagnostic était basé sur l’examen cytologique et clinique. L’examen cytologique a m...
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Disseminated histoplasmosis diagnosed in the bone marrow of an HIV-infected patient: First case imported in Tunisia
We report a first case of disseminated histoplasmosis in a 34-year-old woman, infected with human immunodeficiency virus (HIV), originating from Ivory Coast and living in Tunisia for 4 years. She was complaining from fever, chronic diarrhoea and pancytopenia. The Histoplasma capsulatum var. capsulatum was identified by direct microscopic examination of the bone marrow. She was treated by Amphotericin B, relayed by itraconazole. Even though a regression of symptoms and normalization of blood cell count (BCC), the patient died in a respiratory distress related to CMV hypoxemic pneumonia. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Chronic mucocutaneous candidiasis, a case study and literature review
Publication date: March 2018Source: Journal de Mycologie Médicale, Volume 28, Issue 1Author(s): A.R. Khosravi, P. Mansouri, Z. Saffarian, G. Vahedi, D. NikaeinAbstractChronic mucocutaneous candidiasis (CMC) is a clinically heterogeneous disease. Some immunologic and hormonal abnormalities have been associated with CMC. The factors that predispose host to CMC infection could be autosomal or acquisitive. The disease usually occurs in childhood. Here, we reviewed the published literature on chronic mucocutaneous candidiasis and a four years old girl is presented with CMC. She had a history of recurrent thrush and otomycosis ...
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Necessity to identify the causative agent for appropriate treatment in fungal corneal ulcer: an in vitro study
ConclusionIdentification of causative fungi is necessary before antifungal treatment. Lowest voriconazole MIC promotes its use as 1st line drug. Comparative higher natamycin MIC, especially against Aspergillus species, warns clinician to have MIC in each case of a non-responding fungal corneal ulcer. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
In vitro antifungal activity of cassia fistula extracts against fluconazole resistant strains of Candida species from HIV patients
ConclusionThe present study reports the antifungal activity of various extracts of Cassia fistula for the first time against fluconazole resistant Candida isolates. We can conclude that the polyphenolic compound gallic acid is a potent natural antifungal agent. Further research is needed to assess the pharmacokinetic property. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Prevalence of vulvovaginal candidiasis in pregnancy at three health centers in Burkina Faso
ConclusionsThis study revealed a high prevalence of non-C. albicans species. The syndromic management guidelines for VVC in Burkina Faso will be revised to include a specific protocol for pregnant women. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
