The susceptibility of Candida albicans strains to selected anticancer drugs and flucytosine, relevance of the presence of self-splicing intron in 25S rDNA
ConclusionThe antifungal potential of tested substances, especially the simultaneous action of fluorouracil and folinate (combination used in oncology), is encouraging further research. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - December 11, 2018 Category: Biology Source Type: research
Is Aspergillus lateral device ready to implement to the daily practice? The question rising from the new European Invasive Aspergillosis management guideline
Publication date: Available online 4 December 2018Source: Journal de Mycologie MédicaleAuthor(s): G. Metan (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - December 4, 2018 Category: Biology Source Type: research
pages informations
Publication date: December 2018Source: Journal de Mycologie Médicale, Volume 28, Issue 4Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 30, 2018 Category: Biology Source Type: research
Systemic infection with Candida Albicans in breast tumor bearing mice: Cytokines dysregulation and induction of regulatory T cells
ConclusionIt seems that systemic infection with C. albicans could not only induce regulatory T cells but also result in dysregulation of cytokine network and thereby facilitate tumor growth. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 23, 2018 Category: Biology Source Type: research
Subcutaneous phaeohyphomycosis caused by Amesia atrobrunnea in Kuwait
Publication date: Available online 13 November 2018Source: Journal de Mycologie MédicaleAuthor(s): A. Jeragh, S. Ahmad, Z. Khan, R.Y. Tarazi, S. Ajmi, L. Joseph, S. Varghese, S. VayalilAbstractThe recently described genus Amesia encompasses four species but only Amesia atrobrunnea (= Chaetomium atrobrunneum) is known to be pathogenic to humans. Here, we describe a case of subcutaneous phaeohyphomycosis in Kuwait in an apparently immunocompetent patient diagnosed by direct microscopy of the infected tissue and culture. The identity of A. atrobrunnea was established by typical morphological characteristics and by seque...
Source: Journal of Medical Mycology - November 14, 2018 Category: Biology Source Type: research
Murine model of invasive pulmonary Aspergillosis: Follow-up of tissue injury, fungal burden and mortality with distinct elastase production strains
Publication date: Available online 13 November 2018Source: Journal de Mycologie MédicaleAuthor(s): R.L.H. Silva, E. Rosa-Milani, M.O. Brunaldi, C.M.L. MaffeiAbstractTo study invasive pulmonary Aspergillosis (IPA), we depleted neutrophils in mice using the monoclonal antibody anti-Gr-1/Ly-6G. Immunocompetent and neutropenic mice were infected via intratracheal with conidia of Aspergillus fumigatus clinical isolates, characterized as either higher or lower elastase producers. Neutropenic animals exhibited 100% mortality in 5 days, for both strains, and were observed survival curves overlapped, lungs with angioinvasion, rupt...
Source: Journal of Medical Mycology - November 14, 2018 Category: Biology Source Type: research
First case of proven invasive pulmonary infection due to Trichoderma longibrachiatum in a neutropenic patient with acute leukemia
We report in this work the first proven case of invasive pulmonary infection due to T. longibrachiatum in a 69-year-old white male with hematologic malignancy. The patient was successfully treated initially with voriconazole alone followed by a combination of voriconazole and caspofungine. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 27, 2018 Category: Biology Source Type: research
An atypical occurrence of Aspergillosis in leukemic patient: Brief description of a clinical case
Publication date: Available online 23 October 2018Source: Journal de Mycologie MédicaleAuthor(s): L. Pastrone, M.-T. Corsetti, L. Depaoli, S. Sampò, M. Colonna, A. RocchettiAbstractHerein we describe a 43 year-old Caucasian female patient with acute myeloid leukemia that developed an unconventional form of invasive Aspergillosis. For therapeutic reasons, a Groshong-type central venous catheter was positioned. Monitoring the patient's clinical conditions, positive values for C-reactive protein and galactomannan were correlated with a probably Aspergillosis. Surprisingly no pulmonary evidences were observed. Due to worseni...
Source: Journal of Medical Mycology - October 24, 2018 Category: Biology Source Type: research
Aspergillus fumigatus conidia stimulate lung epithelial cells (TC-1 JHU-1) to produce IL-12, IFNγ, IL-13 and IL-17 cytokines: Modulatory effect of propolis extract
This study was designed to evaluate the effect of A. fumigatus conidia on IL-12, IFNγ, IL-13 and IL-17 release from mouse LECs and to investigate the effect of propolis on cytokines modulation. Cells were divided to two groups, one was exposed to 3 × 104 conidia of Aspergillus fumigatus and another group was treated by propolis (25 μg/mL) as well as exposed to A. fumigatus conidia. Cytokines IL-13, IL-12, IFNγ and IL-17 were measured at times 0, 6 and 12 hours after exposure using ELISA assay. The results indicated that A. fumigatus could increase the release of the cytokines with IL-13 and IL-17...
Source: Journal of Medical Mycology - October 23, 2018 Category: Biology Source Type: research
MALDI-TOF MS identification of Malassezia species isolated from patients with pityriasis versicolor at the seafarers’ medical service in Dakar, Senegal
Publication date: Available online 16 October 2018Source: Journal de Mycologie MédicaleAuthor(s): K. Diongue, O. Kébé, M.D. Faye, D. Samb, M.A. Diallo, M. Ndiaye, M.C. Seck, A.S. Badiane, S. Ranque, D. NdiayeAbstractPityriasis versicolor (PV) is a superficial mycosis caused by yeast of the genus Malassezia. The most common isolated Malassezia species in PV lesions differ among M. furfur, M. globosa and M. sympodialis. We purpose to determine the distribution of Malassezia species in PV patients at the seafarers’ medical service in Dakar, Senegal and to examine whether any association between identified Malassezia spec...
Source: Journal of Medical Mycology - October 17, 2018 Category: Biology Source Type: research
Tacrolimus, not triamcinolone acetonide, interacts synergistically with itraconazole, terbinafine, bifonazole, and amorolfine against clinical dermatophyte isolates
ConclusionsCompared with TRI, TAC showed better synergy when combined with antifungal agents, especially topical TRB and BIZ, against dermatophyte isolates. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 16, 2018 Category: Biology Source Type: research
Molecular epidemiology of environmental Cryptococcus species isolates based on amplified fragment length polymorphism
ConclusionMore research efforts should be employed to isolate C. gattii species complex from environmental niches in Iran and provide additional evidence related to novel molecular types. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 13, 2018 Category: Biology Source Type: research
The little story of the Journal de Mycologie Médicale/Journal of Medical Mycology
Publication date: Available online 24 September 2018Source: Journal de Mycologie MédicaleAuthor(s): J.-M. Bastide (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 5, 2018 Category: Biology Source Type: research
Molecular characterization of Aspergilli isolated from outdoor air
Publication date: Available online 3 October 2018Source: Journal de Mycologie MédicaleAuthor(s): S. Aghaei-Gharehbolagh, M. Shams-Ghahfarokhi, S. Amanloo, M. Razzaghi-AbyanehAbstractUbiquitous airborne conidia of the genus Aspergillus are responsible for a diverse group of human disorders from allergy to life treating invasive aspergillosis and mycotoxicoses. The aim of this study was to determine the population structure of Aspergillus isolated from outdoor air in Tehran by comparing the nucleotide sequences of ITS region and the PCR-RFLP molecular method. Internal transcribed spacer domains of 47 Aspergillus spp. were a...
Source: Journal of Medical Mycology - October 5, 2018 Category: Biology Source Type: research
Mucormycosis outbreak due to Rhizopus microsporus after arthroscopic anterior cruciate ligament reconstruction surgery evaluated by RAPD and MALDI-TOF Mass spectrometry
ConclusionsThe established genetic/mass spectra relatedness between the three post-surgery isolates suggests that these cases may be considered a healthcare-associated mucormycosis outbreak. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - September 22, 2018 Category: Biology Source Type: research
