The First Case of Fingernail Onychomycosis Due to Neoscytalidium novaehollandiae, Molecular Identification and Antifungal Susceptibility
Publication date: Available online 20 December 2019Source: Journal de Mycologie MédicaleAuthor(s): Gh.R. Shokoohi, S. Ansari, A. Abolghazi, M. Gramishoar, S. Nouripour-Sisakht, H. Mirhendi, K. MakimuraAbstractOnychomycosis is considered a fungal nail infection caused mainly by dermatophytes, yeasts and non-dermatophyte molds including dematiaceous fungi. Onychomycosis caused by non-dermatophyte molds is a health problem in the medical environment as the patients frequently return to outpatient clinics seeking new therapeutic modalities. Here, we report the first case of onychomycosis caused by a black fungus, Neoscytalidi...
Source: Journal of Medical Mycology - December 21, 2019 Category: Biology Source Type: research
Cryptococcus and cryptococcosis in Iran during 1969–2019: A systematic review and meta-analysis
ConclusionsGiven the significant risk of Cryptococcus species for susceptible humans, mainly HIV-infected patients, it seems quite necessary to adopt concrete preventive strategies to pinpoint the environmental habitats of this yeast. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - December 19, 2019 Category: Biology Source Type: research
Efficacy of miltefosine therapy against subcutaneous experimental pythiosis in rabbits
This study indicates that miltefosine has limited efficacy against pythiosis and furthers in vitro and in vivo studies are necessary to determine the possible potential of this drug in the treatment of pythiosis. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - December 17, 2019 Category: Biology Source Type: research
Unusual extra-podal fungal mycetoma with black grains in a Senegalese child
We report an exceptional case of cervical fungal mycetoma that occurred in a 13-year-old Senegalese child. He consulted for a cervico-submandibular tumefaction with multiple sinuses and black grains discharge evolving since 6 years, associated to laryngeal dyspnoea. Mycological examination with culture isolated Madurella mycetomatis. Cervical CT Scan showed bone and soft tissue invasion. Terbinafine alone was administered. During the evolution, tracheotomy was performed following the aggravation of the laryngeal disorders. Death from severe sepsis occurred after 8 months of evolution. The particularities of our case are th...
Source: Journal of Medical Mycology - December 10, 2019 Category: Biology Source Type: research
A case report of catheter-related bloodstream infection due to Trichosporon coremiiforme in a patient with secondary neutropenia to HIV
Publication date: Available online 6 December 2019Source: Journal de Mycologie MédicaleAuthor(s): Victoria Monzani, Susana Córdoba, Matías Vivot, Bárbara Arias, Walter Vivot, Wanda Szusz, Patricia Castellaro, Andrea Appendino, Constanza Giselle TavernaAbstractHere, we describe an invasive infection due to Trichosporon coremiiforme in an HIV positive patient with neutropenia. The strain was first erroneously identified as Trichosporon asahii by conventional methods, but correctly identified by mass spectrometry using matrix-assisted laser desorption/ionization time-of-flight technology (MALDI-TOF MS) and ribosomal DNA s...
Source: Journal of Medical Mycology - December 7, 2019 Category: Biology Source Type: research
Cerebral phaeohyphomycosis due to Cladophialophora bantiana in a French Guianese child
We report a case of cerebral phaeohyphomycosis, a fungal brain infection due to a dark (dematiaceous) fungi in a 6-year-old French Guyanese boy. The child presented fever and drowsiness due to several paraventricular brain abscesses. Neurological surgeries were performed to reduce intracranial hypertension and to obtain abscess biopsies. Mycological cultures of intraoperative samples led to the diagnosis of cerebral phaeohyphomycosis due to Cladophialophora bantiana. The patient neurological status deteriorated and remained critical after several weeks of combination antifungal therapy with voriconazole 8 mg/kg/day, liposo...
Source: Journal of Medical Mycology - December 7, 2019 Category: Biology Source Type: research
Exploring the molecular mechanism of azole resistance in Aspergillus fumigatus
Publication date: Available online 6 December 2019Source: Journal de Mycologie MédicaleAuthor(s): Peiying Chen, Juan Liu, Meihua Zeng, Hong SangAbstractAspergillus infections are increasingly recognized as a global health problem because of limited antifungal drugs and occurrence of azole resistance worldwide. More cyp51-mediated and non-cyp51-mediated mechanisms of azole resistance have been identified in clinical and laboratory studies in recent years with applications of molecular biotechnology including next-generation sequencing, reverse genetics and so on. In this review, current research on the molecular mechanisms...
Source: Journal of Medical Mycology - December 7, 2019 Category: Biology Source Type: research
Cryptococcus and cryptococcosis in Iran during 1969-2019: A systematic review and meta-analysis
Conclusions: Given the significant risk of Cryptococcus species for susceptible humans, mainly HIV-infected patients, it seems quite necessary to adopt concrete preventive strategies to pinpoint the environmental habitats of this yeast. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - December 7, 2019 Category: Biology Source Type: research
Editorial Board
Publication date: December 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 4Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 29, 2019 Category: Biology Source Type: research
Contents
Publication date: December 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 4Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 29, 2019 Category: Biology Source Type: research
Antifungal resistance in dermatophytes: Emerging problem and challenge for the medical community
Publication date: December 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 4Author(s): M. Monod (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 29, 2019 Category: Biology Source Type: research
Page informations
Publication date: December 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 4Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 29, 2019 Category: Biology Source Type: research
Sporotrichosis caused by Sporothrix brasiliensis in Argentina: Case report, molecular identification and in vitro susceptibility pattern to antifungal drugs
ConclusionsThis study contributed to the molecular epidemiology of Sporothrix species in Argentina and the characterization of the in vitro susceptibility pattern of S. brasiliensis isolates recovered from a cat and two humans involved in this case of zoonotic sporotrichosis. Bearing in mind the “One Health” concept, the experience described in the present study highlights the need for future strategies for sporotrichosis treatment, control and prevention. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - November 13, 2019 Category: Biology Source Type: research
Carbohydrate hitched imidazoles as agents for the disruption of fungal cell membrane
Publication date: Available online 7 November 2019Source: Journal de Mycologie MédicaleAuthor(s): Deepa Deswal, Pratibha Shukla, Chandra Sourabh Azad, Anudeep Kumar NarulaAbstractThe fungal diseases represent an increasing global health burden and have transformed from a rare curiosity to the leading cause of human mortality. The present manuscript reports the antifungal potential of two novel compounds possessing a carbohydrate and an imidazole moiety. Antifungal susceptibility test determined the growth inhibition potential of the synthesized compounds against Aspergillus niger 9689 and it was observed that compounds D ...
Source: Journal of Medical Mycology - November 9, 2019 Category: Biology Source Type: research
Thymus vulgaris essential oil and thymol inhibit biofilms and interact synergistically with antifungal drugs against drug resistant strains of Candida albicans and Candida tropicalis
Publication date: Available online 7 November 2019Source: Journal de Mycologie MédicaleAuthor(s): Huma Jafri, Iqbal AhmadABSTRACTRole of biofilm in disease development and enhance tolerance to antifungal drugs among Candida species has necessitated search for new anti-fungal treatment strategy. Interference in pathogenic biofilm development by new antifungal compounds is considered as an attractive anti-infective strategy. Therefore, the objective of this study was to evaluate Thymus vulgaris essential oil and its major active compound, thymol for their potential to inhibit and eradicate biofilms alone and in combination ...
Source: Journal of Medical Mycology - November 9, 2019 Category: Biology Source Type: research
