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A novel AVPR2 gene mutation of X-linked congenital nephrogenic diabetes insipidus in an Asian pedigree
Polyuria and polydipsia are the characteristics of congenital nephrogenic diabetes insipidus (CNDI). Approximately 90% of all patients with CNDI have X-linked hereditary disease, which is due to a mutation of the arginine vasopressin receptor 2 (AVPR2) gene. This case report describes a 54-year-old male with polyuria and polydipsia and several male members of his pedigree who had the same symptoms. The proband was diagnosed with diabetes insipidus using a water-deprivation and arginine vasopressin stimulation test. Genomic DNA from the patient and his family members was extracted and the AVPR2 gene was sequenced. A novel m...
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Guo, W.-H., Li, Q., Wei, H.-Y., Lu, H.-Y., Qu, H.-Q., Zhu, M. Tags: Case Report Source Type: research
Evaluation of the anticoagulant effect and timing of the concomitant use of S-1 and warfarin
Conclusions
These findings suggest that the timing of WF use in relation to S-1 chemotherapy might not be an important factor for PT-INR, although the low patient numbers included in the study should be taken into consideration. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Suzuki, S., Ikegawa, K., Yamamoto, K., Saito, S. Tags: Clinical Note Source Type: research
Incidence and characteristics of hepatitis E virus infection in children in Assiut, Upper Egypt
Conclusions
HEV is a significant cause of AVH among children in Upper Egypt. Contamination of drinking water appears to be a major source of infection. Screening for HEV should be considered in all Egyptian children with AVH. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Hasan, G., Assiri, A., Marzuuk, N., Daef, E., Abdelwahab, S., Ahmed, A., Mohamad, I., Al-Eyadhy, A., Alhaboob, A., Temsah, M.-H. Tags: Clinical Reports Source Type: research
Relationship between bone mineral density and dietary intake of {beta}-carotene, vitamin C, zinc and vegetables in postmenopausal Korean women: a cross-sectional study
Conclusion
In postmenopausal Korean women, β-carotene, vitamin C, zinc and sodium intakes were positively associated with bone mass. Furthermore, frequency of vegetable consumption was positively associated with femoral neck and total hip T-scores. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Kim, D. E., Cho, S. H., Park, H. M., Chang, Y. K. Tags: Clinical Reports Source Type: research
Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors
Conclusions
Kidney diseases in the elderly have distinctive characteristics. Requirement for RRT was associated with poor prognosis in the elderly with biopsy-proven kidney diseases. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Chen, Y., Li, P., Cui, C., Yuan, A., Zhang, K., Yu, C. Tags: Clinical Reports Source Type: research
Ramipril + amlodipine and ramipril + hydrochlorothiazide fixed-dose combinations in relation to patient adherence
Conclusion
Ramipril + amlodipine had significantly higher 1-year treatment adherence than ramipril + hydrochlorothiazide in patients with hypertension. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Simonyi, G., Ferenci, T., Alföldi, S., Farsang, C. Tags: Clinical Reports Source Type: research
Alleviated negative rather than positive attentional bias in patients with depression in remission: an eye-tracking study
Conclusions
This present study showed that the negative attentional bias of RD patients was successfully eased, but their positive attentional bias was still insufficient. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Li, M., Lu, S., Wang, G., Feng, L., Fu, B., Zhong, N. Tags: Research Reports Source Type: research
Comparison of saddle, lumbar epidural and caudal blocks on anal sphincter tone: A prospective, randomized study
Conclusions
Saddle block was more effective than lumbar epidural or caudal block for depressing anal sphincter tone. No differences were detected between lumbar epidural and caudal blocks. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Shon, Y.-J., Huh, J., Kang, S.-S., Bae, S.-K., Kang, R.-A., Kim, D.-K. Tags: Research Reports Source Type: research
Evaluation of a liquid culture system in the detection of mycobacteria at an antituberculosis institution in China; A retrospective study
Conclusions
The M960 system had better diagnostic capability than L–J culture. Clinical value may be maximized by combining results from both methods. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Zhao, P., Yu, Q., Chen, L., Zhang, M. Tags: Research Reports Source Type: research
The effect and mechanism of action of metformin on in vitro FaDu cell proliferation
Conclusions
Metformin significantly inhibited FaDu cell proliferation, possibly via downregulation of miR-21-5p and upregulation of PDCD4. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Sun, R., Ma, X., Cai, X., Pan, X., Liu, D. Tags: Research Reports Source Type: research
Incidence of insulin resistance and diabetes in patients with portosystemic shunts without liver dysfunction
Conclusions
Patients with chronic HSJ and PSS without liver dysfunction had a high incidence of IR and diabetes. The study showed that PSS and IR are related and therefore patients with PSS should be screened for IR and vice versa. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Li, Y., Yang, G., Qiang, J., Cai, S., Zhou, H. Tags: Research Reports Source Type: research
Impact of urethral catheterization on uroflow during pressure-flow study
Conclusion
Urethral catheterization adversely impacts uroflow in patients with benign prostatic hyperplasia, female stress incontinence, spinal injury or spina bifida. Free uroflowmetry should be performed before pressure-flow study. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Zhu, B. S., Jiang, H. C., Li, Y. Tags: Research Reports Source Type: research
Differential knee skin temperature following total knee arthroplasty and its relationship with serum indices and outcome: A prospective study
Conclusions
Differential knee skin temperature elevation 12 months post-TKA may be a normal surgical response. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Zeng, Y., Feng, W., Qi, X., Li, J., Chen, J., Lu, L., Deng, P., Zeng, J., Li, F. Tags: Research Reports Source Type: research
Effect-site concentration of remifentanil for smooth inhalational induction with desflurane
Conclusion
Prior administration of remifentanil could provide smooth inhalational induction with desflurane in a stepwise increment. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Yoo, J. Y., Lee, S. Y., Jeong, H. W., Park, H. B., Chae, Y. J. Tags: Research Reports Source Type: research
Cell-free DNA increase over first 48 hours in emergency intensive care unit predicts fatal outcome in patients with shock
Conclusions
Increased circulating cf-DNA levels in EICU patients with shock are associated with risk of death and measuring cf-DNA change over 48 h improves risk prediction. The present study suggests that cf-DNA may serve as a viable plasma biomarker of mortality risk in EICU patients with shock. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - October 8, 2016 Category: Research Authors: Xia, D. L., Zhang, H., Luo, Q. L., Zhang, A. F., Zhu, L. X. Tags: Research Reports Source Type: research