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Journal of Internal Medicine,Volume 283, Issue 3, Page 330-330, March 2018. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Combination therapy strategies for improving PD ‐1 blockade efficacy: A new era in cancer immunotherapy
This article is protected by copyright. All rights reserved. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 26, 2017 Category: Internal Medicine Authors: Partha S. Chowdhury, Kenji Chamoto, Tasuku Honjo Tags: Review Article Source Type: research

Chronic inflammation predicts long ‐term mortality in patients with Raynaud′s phenomenon
ConclusionIn Raynaud's phenomenon, laboratory markers that can be attributed to a chronic inflammatory state independently yield prognostic information in addition to the presence of abnormal nailfold capillaries and ANA. Among all prognostic markers, the hemoglobin concentration is most strongly related to patients’ mortality in Raynaud's phenomenon.This article is protected by copyright. All rights reserved. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 25, 2017 Category: Internal Medicine Authors: Markus Mueller, Michael E. Gschwandtner, Jutta Gamper, Georgiana ‐Aura Giurgea, Hans P. Kiener, Thomas Perkmann, Renate Koppensteiner, Oliver Schlager Tags: Original Article Source Type: research

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Journal of Internal Medicine,Volume 283, Issue 3, Page 293-302, March 2018. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 25, 2017 Category: Internal Medicine Source Type: research

A functional variant in the promoter region regulates the C ‐reactive protein gene and is a potential candidate for increased risk of atrial fibrillation
(Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 19, 2017 Category: Internal Medicine Tags: Corrigendum Source Type: research

Introduction to the symposium ‘Targeted therapy in B‐cell malignancies’
Content List ‐ Read more articles from the symposium: Targeted therapy in B‐cell malignancies. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 19, 2017 Category: Internal Medicine Authors: K. E. Smedby, R. Rosenquist Tags: Introduction Source Type: research

SYMPOSIUM: Targeted therapy in B ‐cell malignancies
(Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 19, 2017 Category: Internal Medicine Tags: Symposium Source Type: research

Issue Information ‐ Editorial Board
(Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 19, 2017 Category: Internal Medicine Tags: Issue Information Source Type: research

Human papillomavirus vaccination of adult women and risk of autoimmune and neurological diseases
ConclusionUnmasking of conditions at vaccination visits is a plausible explanation for the increased risk associated with qHPV in this study because coeliac disease is underdiagnosed in Scandinavian populations. In conclusion, our study of serious adverse event rates in qHPV‐vaccinated and qHPV‐unvaccinated adult women 18–44 years of age did not raise any safety issues of concern. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 18, 2017 Category: Internal Medicine Authors: A. Hviid, H. Svanstr öm, N. M. Scheller, O. Grönlund, B. Pasternak, L. Arnheim‐Dahlström Tags: Original Article Source Type: research

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Journal of Internal Medicine, Ahead of Print. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 17, 2017 Category: Internal Medicine Source Type: research

Involvement of platelet ‐derived growth factor ligands and receptors in tumorigenesis
Abstract Platelet‐derived growth factor (PDGF) isoforms and their receptors have important roles during embryogenesis, particularly in the development of various mesenchymal cell types in different organs. In the adult, PDGF stimulates wound healing and regulates tissue homeostasis. However, overactivity of PDGF signalling is associated with malignancies and other diseases characterized by excessive cell proliferation, such as fibrotic conditions and atherosclerosis. In certain tumours, genetic or epigenetic alterations of the genes for PDGF ligands and receptors drive tumour cell proliferation and survival. Examples inc...
Source: Journal of Internal Medicine - October 17, 2017 Category: Internal Medicine Authors: C. ‐H. Heldin, J. Lennartsson, B. Westermark Tags: Review Source Type: research

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Journal of Internal Medicine,Volume 283, Issue 3, Page 282-292, March 2018. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 16, 2017 Category: Internal Medicine Source Type: research

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Journal of Internal Medicine,Volume 283, Issue 3, Page 314-327, March 2018. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 16, 2017 Category: Internal Medicine Source Type: research

Comparison of Bleeding Risk Scores in Patients with Atrial Fibrillation:Insights from the RE ‐LY Trial
ConclusionsAmong the current clinical bleeding risk scores, the ORBIT score demonstrated the best discrimination and calibration. All the scores demonstrated, to a variable extent, an interaction with bleeding risk associated with dabigatran or warfarin.This article is protected by copyright. All rights reserved. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 16, 2017 Category: Internal Medicine Authors: Marco Proietti, Ziad Hijazi, Ulrika Andersson, Stuart J Connolly, John W Eikelboom, Michael D Ezekowitz, Deirdre A. Lane, Jonas Oldgren, Vanessa Roldan, Salim Yusuf, Lars Wallentin, Tags: Original Source Type: research

Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts
ConclusionAmongst adults, SHyper was associated with increased femoral neck bone loss, potentially contributing to the increased fracture risk. (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - October 16, 2017 Category: Internal Medicine Authors: D. Segna, D. C. Bauer, M. Feller, C. Schneider, H. A. Fink, C. E. Aubert, T. ‐H. Collet, B. R. Costa, K. Fischer, R. P. Peeters, A. R. Cappola, M. R. Blum, H. A. Dorland, J. Robbins, K. Naylor, R. Eastell, A. G. Uitterlinden, F. Rivadeneira Ramirez, A. Tags: Original Article Source Type: research