Journal of integrative bioinformatics 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.PharmoCo: a graph-based visualization of pharmacogenomic plausibility check reports for clinical decision support systems
J Integr Bioinform. 2023 Dec 28;20(4):20230026. doi: 10.1515/jib-2023-0026. eCollection 2023 Dec 1.ABSTRACTThe first approaches in recent years for the integration of pharmacogenomic plausibility checks into clinical practice show both a promising improvement in the drug therapy safety, but also difficulties in application. One of the difficulties is the meaningful interpretation of the text-based results by the medical practitioner. We propose here as an appropriate and sensible solution to avoid misunderstandings and to include evidence-based, pharmacogenomic recommendations in prescriptions, which should be the graph-ba...
Source: Journal of integrative bioinformatics - December 27, 2023 Category: Bioinformatics Authors: Lena Raupach Cassandra K önigs Source Type: research
PharmoCo: a graph-based visualization of pharmacogenomic plausibility check reports for clinical decision support systems
J Integr Bioinform. 2023 Dec 28. doi: 10.1515/jib-2023-0026. Online ahead of print.ABSTRACTThe first approaches in recent years for the integration of pharmacogenomic plausibility checks into clinical practice show both a promising improvement in the drug therapy safety, but also difficulties in application. One of the difficulties is the meaningful interpretation of the text-based results by the medical practitioner. We propose here as an appropriate and sensible solution to avoid misunderstandings and to include evidence-based, pharmacogenomic recommendations in prescriptions, which should be the graph-based visualizatio...
Source: Journal of integrative bioinformatics - December 27, 2023 Category: Bioinformatics Authors: Lena Raupach Cassandra K önigs Source Type: research
Gene-network based analysis of human placental trophoblast subtypes identifies critical genes as potential targets of therapeutic drugs
J Integr Bioinform. 2023 Dec 22. doi: 10.1515/jib-2023-0011. Online ahead of print.ABSTRACTDuring early pregnancy, extravillous trophoblasts (EVTs) play a crucial role in modifying the maternal uterine environment. Failures in EVT lineage formation and differentiation can lead to pregnancy complications such as preeclampsia, fetal growth restriction, and pregnancy loss. Despite recent advances, our knowledge on molecular and external factors that control and affect EVT development remains incomplete. Using trophoblast organoid in vitro models, we recently discovered that coordinated manipulation of the transforming growth ...
Source: Journal of integrative bioinformatics - December 21, 2023 Category: Bioinformatics Authors: Andreas Ian Lackner J ürgen Pollheimer Paulina Latos Martin Kn öfler Sandra Haider Source Type: research
