Preventing healthcare-associated infection by sharing research, evidence and best practice
Publication date: Available online 12 December 2018Source: Journal of Hospital InfectionAuthor(s): J. Gray, G. Winzor, N. Mahdia, B. Oppenheim, A. Johnston (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 12, 2018 Category: Infectious Diseases Source Type: research

Analysis of awareness and knowledge about Mycobacterium chimaera invasive infections among doctors and medical students
Publication date: Available online 10 December 2018Source: Journal of Hospital InfectionAuthor(s): Y. Ortiz-Martínez, C. Galindo-Regino, E. Salcedo-Rodríguez, H.J. Rojas-Moreno, M.L. Beltrán-Avilez (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 11, 2018 Category: Infectious Diseases Source Type: research

The method used to dry washed hands affects the number and type of transient and residential bacteria remaining on the skin
Publication date: Available online 8 December 2018Source: Journal of Hospital InfectionAuthor(s): Reinier Mutters, Sarah L. WarnesSummaryBackgroundWidespread antibiotic resistance has led to fears that we are entering a pre-antibiotic era and the relatively simple premise of hand washing to reduce transfer of bacteria and viruses has never been more important. Much of the emphasis has been on handwashing technique, type of soap and maintaining compliance but effective drying of the hands is just as important.AimTo compare the efficacy of drying washed hands with a jet air dryer or paper towels to remove transient bacterial...
Source: Journal of Hospital Infection - December 9, 2018 Category: Infectious Diseases Source Type: research

In-house validation of the cobas Liat influenza A/B and RSV assay for use with gargles, sputa and endotracheal secretions
Publication date: Available online 5 November 2018Source: Journal of Hospital InfectionAuthor(s): E.J. Goldstein, R.N. Gunson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 8, 2018 Category: Infectious Diseases Source Type: research

Complex design of surgical instruments as barrier for cleaning effectiveness, favouring biofilm formation
ConclusionSoil and/or biofilms were evident on complex-design RSIs following 20 cycles of contamination and reprocessing, even using the reference standard method of cleaning. Although the depth gauges could be disassembled, biological residues and biofilm accumulated in its lumen. The current design of these RSIs prevents removal of all biological soil and this may have an adverse effect on patient outcome. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 8, 2018 Category: Infectious Diseases Source Type: research

Prospective investigation of carbapenem-resistant Klebsiella pneumonia transmission among the staff, environment, and patients in five major intensive care units, Beijing
ConclusionsThe contamination of ICU environment and staff’s hands, gloves or gowns is frequent with CRKP patients. Our study also supports the hypothesis that an association between environmental contamination and transmission of CRKP bacteria in ICUs. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 7, 2018 Category: Infectious Diseases Source Type: research

The impact of penicillin allergy records on carbapenem prescribing: an observational retrospective cohort study: Meropenem prescribing associated with penicillin allergy records
This study measured the impact of penicillin allergy labels on meropenem prescribing.Rates of meropenem prescribing were compared between patients with a penicillin allergy record and patients without such a record. Potential confounders were also collected (age, sex, co-morbidity).Of the 21,272 patients with no penicillin allergy 225 (1.06%) were prescribed meropenem, whereas of the 3443 with penicillin allergy 240 (6.97%) were prescribed meropenem.Meropenem prescribing is associated with a patient’s penicillin allergy record. Given that many penicillin allergy records are incorrect, addressing spurious penicillin a...
Source: Journal of Hospital Infection - December 7, 2018 Category: Infectious Diseases Source Type: research

HIV post exposure prophylaxis knowledge among healthcare workers in a hospital from Colombia
Publication date: Available online 7 December 2018Source: Journal of Hospital InfectionAuthor(s): Yeimer Ortiz-Martínez, Keila Mendoza-Borja, Martha L. Beltrán-Avilez, Kevin Vásquez-Rada, Andrea Buelvas-Pérez, María F. Ortega-Gaibao, Jhon Lafaurie-Rojas (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 7, 2018 Category: Infectious Diseases Source Type: research

Impact of participation in a surgical site infection surveillance network: results from a large international cohort study
ConclusionIn this large, international cohort study, pooled SSI rates showed a were associated with a stable and sustainable decrease after joining a SSI surveillance network; a causal relationship is possible, although unproven. There was heterogeneity in procedure-specific trends. These findings support the pivotal role of surveillance in reducing infection rates and call for widespread implementation of hospital-based SSI surveillance in high-income countries. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 7, 2018 Category: Infectious Diseases Source Type: research

Association of nurse staffing and nursing workload with ventilator-associated pneumonia and mortality: a prospective, single-center cohort study
ConclusionsLower nurse staffing and increased nursing workload are associated with ventilator-associated pneumonia and mortality, demonstrating that adequate staffing is a prerequisite for the availability and quality of critical care services. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 7, 2018 Category: Infectious Diseases Source Type: research

Are perineal swabs required as part of initial staff screening in healthcare associated Streptococcus pyogenes outbreaks?
Publication date: Available online 5 December 2018Source: Journal of Hospital InfectionAuthor(s): Manjula Meda, Victoria Gentry, Amanda Walker (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 6, 2018 Category: Infectious Diseases Source Type: research

Workplace Vaccination Against Measles In a Teaching Hospital of Rome
Publication date: Available online 6 December 2018Source: Journal of Hospital InfectionAuthor(s): Luca Coppeta, Antonio Pietroiusti, Luca Morucci, Anna Neri, Mariacarmela Ferraro, Andrea Magrini (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 6, 2018 Category: Infectious Diseases Source Type: research

Attributable Clinical and Economic Burden of Carbapenem-Nonsusceptible Gram-Negative Infections in Patients Hospitalized With Complicated Urinary Tract Infections
We examined the clinical and economic burden attributable to Gram-negative carbapenem-nonsusceptible (C-NS; resistant/intermediate) versus carbapenem-susceptible (C-S) infections in 78 United States (US) hospitals.MethodsAll nonduplicate C-NS and C-S urine source isolates were analyzed. A subset had principal diagnosis ICD-9-CM codes denoting cUTI. Collection time (
Source: Journal of Hospital Infection - December 1, 2018 Category: Infectious Diseases Source Type: research

Evaluation of the mechanical cleaning efficacy of dental handpieces
ConclusionManufacturers should optimize the cleaning device parameters, based on the Sinner circle (grouping compensatory parameters which influence the effectiveness of a cleaning process, such as pressure, temperature, time, detergent concentration), to improve cleaning efficacy and enable dental surgeons to ensure the safety. Although PIDTest© are the only tool to provide visual indications on the cleaning efficacy of washer-disinfectors dedicated to handpieces, manufacturers should continue with the development of improved and validated tools to assess cleaning efficacy. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

Are systematic drain tip or drainage fluid cultures predictive of surgical site infections?
ConclusionSystematic cultures of drain tips or drainage fluids appear not to be relevant, because their positive predictive values were low in the prediction of SSI. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

Hepatitis C virus transmission in a Dutch haemodialysis unit: detailed outbreak investigation using NS5A gene sequencing
ConclusionThis study demonstrates that detailed incident recording in combination with state-of-the-art molecular investigations such as sequencing of the NS5A region resulted in unravelling a set of two HCV transmissions that occurred at an haemodialysis unit. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

The overall bioburden by total colony count does not predict presence of pathogens with high clinical relevance in the environment of hospitals and community
ConclusionTCC poorly predicted presence of PHCR, rendering results from environmental sampling with TCC difficult to interpret. MALDI-TOF technique allows identifying large numbers of isolates at low cost from the environment. Further studies on environmental contamination should use MALDI-TOF to identify all grown pathogens for identification. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

Multi-centre study on cultural dimensions and perceived attitudes of nurses towards influenza vaccination uptake
This study explored how cultural values affected Health Belief Model (HBM) components and the influenza vaccine uptake among nurses across three Asian populations using a survey conducted in 2017 (N = 3971). The vaccination coverages were 33.5% (Brunei), 35.6% (Hong Kong) and 69.5% (Singapore). Three HBM components (perceived susceptibility, perceived benefits and cues to action) were positively associated with vaccination. A direct negative link and an indirect positive link via HBM were observed between collectivism and vaccination, whereas a negative indirect link via HBM between power distance and vaccination was obser...
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

Antiseptic efficacies of waterless hand rub, chlorhexidine scrub, and povidone-iodine scrub in surgical settings: a meta-analysis of randomized controlled trials
ConclusionWHRs and CHG exhibited higher antiseptic efficacies than PI. However, additional studies with consistent outcome measurements and accurate grouping are required to obtain comprehensive results. Moreover, preference, compliance, and the cost determine the selection of hand wash products. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 28, 2018 Category: Infectious Diseases Source Type: research

Directly observed hand hygiene – from healthcare workers to patients
Publication date: Available online 27 November 2018Source: Journal of Hospital InfectionAuthor(s): Vincent C.C. Cheng, Shuk-Ching Wong, Sally C.Y. Wong, Kwok-Yung Yuen (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 27, 2018 Category: Infectious Diseases Source Type: research

Implementation of influenza point-of-care-testing and patient-cohorting during a high-incidence season: a retrospective analysis of impact on infection prevention and control and clinical outcomes
Publication date: Available online 22 November 2018Source: Journal of Hospital InfectionAuthor(s): Jonathan Youngs, Benjamin Marshall, Melissa Farragher, Laura Whitney, Stephen Glass, Cassie Pope, Timothy Planche, Peter Riley, David CarringtonSummaryBackgroundDuring high-incidence influenza seasons, a robust infection prevention and control policy is imperative to reduce nosocomial transmission of influenza.AimTo assess the impact of Emergency Department (ED) influenza point-of-care-testing (POCT) and influenza-ward patient-cohorting on infection prevention and control and clinical outcomes.MethodsInfluenza POCT was operat...
Source: Journal of Hospital Infection - November 22, 2018 Category: Infectious Diseases Source Type: research

Hospital-by-Hospital Carbapenem Use in Japan: A Nationwide Ecological Study
ConclusionsThis study determined hospital-by-hospital patterns of carbapenem use in Japan. Because a single predictive model was not appropriate for all hospitals, tailored models are needed to identify hospitals that are heavy users of carbapenem. These findings may serve as a reference to support further research on antibiotic use in healthcare and aid future policies. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 17, 2018 Category: Infectious Diseases Source Type: research

Staphylococcus aureus meningitis in adults: A comparative cohort study of infections caused by methicillin-resistant and methicillin-susceptible strains
Publication date: Available online 16 November 2018Source: Journal of Hospital InfectionAuthor(s): Vicente Pintado, Rosario Pazos, Manuel Enrique Jiménez-Mejías, Azucena Rodríguez-Guardado, Beatriz Díaz-Pollán, Carmen Cabellos, Juan Manuel García-Lechuz, Jaime Lora-Tamayo, Pere Domingo, Elena Muñez, Diego Domingo, Fernando González-Romo, José Antonio Lepe-Jiménez, Carlos Rodríguez-Lucas, Antonio Gil, Iván Pelegrín, Fernando Chaves, Virginia Pomar, Antonio Ramos, Teresa AlarcónSummaryBackgroundStaphylococcus aureus meningitis i...
Source: Journal of Hospital Infection - November 16, 2018 Category: Infectious Diseases Source Type: research

Dr SWB Newsom (1932–2018)
Publication date: Available online 16 November 2018Source: Journal of Hospital InfectionAuthor(s): Richard Newsom, David Shanson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 16, 2018 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Nosocomial ventriculitis caused by a meticillin- and linezolid-resistant clone of Staphylococcus epidermidis in neurosurgical patients
ConclusionThe high ratio of linezolid consumption in the ICU (7.72–8.10 defined daily dose/100 patient-days) could have selected this resistant clone, which has probably become endemic in the ICU where it could have colonized admitted patients. Infection control and antimicrobial stewardship interventions are essential to prevent the dissemination of this difficult-to-treat pathogen, and to preserve the therapeutic efficacy of linezolid. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Prevention of deep sternal wound infection in cardiac surgery: a literature review
ConclusionThis study identified several measures that prevent DSWI after cardiac surgery that are not frequently applied in current practice. It is recommended that the guidelines on prevention of surgical site infection in cardiac surgery should be updated. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Effect of chlorhexidine skin disinfection and retrosternal gentamicin sponge on post-sternotomy mediastinitis: results from a prospective controlled registry of 2340 patients
ConclusionPreoperative skin disinfection with IPA–CHG is superior to only IPA, and it should be recommended. The addition of a retrosternal gentamicin-releasing sponge further reduces the rate of mediastinitis. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Response to Kaier et al. regarding ‘Estimating the additional costs of surgical site infections’
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): M. Ohno, Y. Shimada, M. Satoh, S. Hori (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Respiratory syncytial virus burden among adults during flu season: an underestimated pathology
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): M. Kestler, P. Muñoz, M. Mateos, D. Adrados, E. BouzaSummaryBackgroundInformation on the role of respiratory syncytial virus (RSV) in adult patients with influenza-like syndrome is scarce.AimTo assess the clinical characteristics of RSV in adult patients with respiratory manifestations during a regular influenza season.MethodsProspective study in a tertiary Spanish hospital from December 2015 to February 2016. The study population included only adult patients with either community-acquired or hospital/healthcare-assoc...
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Outbreak reports
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): J. Gray (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Outbreak of invasive group A streptococcus: investigations using agar settle plates detect perineal shedding from a healthcare worker
ConclusionThis is the first outbreak report demonstrating the use of settle plates in a GAS outbreak investigation on a medical ward, to identify the likely source of the outbreak. Based on this report we recommend that both throat and perineal sites should be sampled if HCW screening is undertaken during an outbreak of GAS. Fabric, soft furnishings should be excluded from clinical areas as well as any adjacent offices because pathogenic bacteria such as GAS may contaminate this environment. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Recommendations for the successful control of a large outbreak of vancomycin-resistant Enterococcus faecium in a non-endemic hospital setting
ConclusionInfection control measures according to international guidelines were insufficient to expose the outbreak to its full extent and control it. Its full extent only became apparent after sustained hospital-wide screening. Successful control of this hospital-wide VRE outbreak was feasible, but required great effort. Final containment and eradication of the epidemic clones was achieved by environmental decontamination with hydrogen peroxide vapour, strict isolation precautions, a VRE quarantine ward and antimicrobial stewardship. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Recurrent outbreaks caused by the same Salmonella enterica serovar Infantis clone in a German rehabilitation oncology clinic from 2002 to 2009
ConclusionsThis study demonstrated important details of hospital-specific epidemiological processes, and alludes to a long-term reservoir of an epidemic clone of S. enterica serovar Infantis either in a backyard flock of poultry or in an inanimate kitchen reservoir. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Utility of MALDI-TOF mass spectrometry in an outbreak investigation of acute endophthalmitis following intravitreal injection
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): A. Angrup, S. Krishnamoorthi, M. Biswal, V. Gautam, P. Ray, A. Agarwal, M.R. Dogra, R. Singh, D. Katoch, V. GuptaSummaryBevacizumab, a recombinant humanized monoclonal antibody to inhibit tumour angiogenesis, is available for off-label use for treating choroidal neovascularization. Outbreaks have been reported after use of this drug, either because of contamination during manufacturing or the practice of multiple doses being administered from a single vial to different patients. In our institute we investigated one endophtha...
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Outbreak of Burkholderia cepacia bacteraemia in a tertiary care centre due to contaminated ultrasound probe gel
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): V.R. Yamunadevi, V. Ramasubramanian, P. Senthur Nambi, P. Samundeewari, N. Ramakrishnan (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Reducing adult cardiac surgical site infections and the economic impact of using multidisciplinary collaboration
Publication date: December 2018Source: Journal of Hospital Infection, Volume 100, Issue 4Author(s): L. Chiwera, N. Wigglesworth, C. McCoskery, G. Lucchese, W. NewsholmeSummaryBackgroundCardiac surgical site infections (SSIs) have devastating consequences and present several challenges for patients and healthcare providers. Adult cardiac SSI surveillance commenced in 2009 at our hospitals, Guy's & St Thomas' NHS Foundation Trust, London, as a patient safety initiative amid reported increased incidence of SSIs. Before this time, infection incidence was unclear because data collection was not standardized.AimTo standardiz...
Source: Journal of Hospital Infection - November 15, 2018 Category: Infectious Diseases Source Type: research

Is malnutrition associated with orthopaedic infections? A single-centre pilot evaluation
Publication date: Available online 13 November 2018Source: Journal of Hospital InfectionAuthor(s): N. Guanziroli, D. Hannouche, I. Uçkay (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 14, 2018 Category: Infectious Diseases Source Type: research

Observation study of water outlet design from a cross infection / user perspective; time for a radical re-think?
ConclusionAlthough hand washing is a key barrier to cross infection poor selection and incorrect use of outlet undermines its effectiveness. Design and incorrect instalment further compromise the intended means of operation of elbow levers. Of equal concern is this risk mostly goes unrecognised. There is an opportunity to improve hand washing safety but it requires engagement across a broad stratum from Government Departments of Health and manufacturers down to the user. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 14, 2018 Category: Infectious Diseases Source Type: research

Instrument cleanliness and protein misfolding disorders
Publication date: Available online 10 November 2018Source: Journal of Hospital InfectionAuthor(s): R. Salmon (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 11, 2018 Category: Infectious Diseases Source Type: research

Microbial water quality management of dental unit water lines at a dental school
This study reports the microbial load of the water from DUWLs of a large dental school over time. The water quality of 231 dental chairs was tested three times over 1.5 years; 175 DUWLs at student clinics and 56 DUWLs at staff clinics. DUWLs at the staff clinics met the Dutch requirement of 100 cfu/ml. An increasing amount of DUWLs at the student clinics complied with this requirement, indicating that the local protocols were adequate, but that the compliance can be improved. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 11, 2018 Category: Infectious Diseases Source Type: research

Broad-spectrum antibiotic prescriptions are unevenly discontinued throughout the week
This study suggested that the broad-spectrum antibiotics tend to be continued over weekends or holidays and discontinued thereafter, probably due to behavioural factors beyond medical indications that need to be addressed in future antimicrobial stewardship initiatives. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 11, 2018 Category: Infectious Diseases Source Type: research

Healthcare Burden of Probable and Proven Invasive Mucormycosis: A Multicenter Cost-of-Illness Analysis of Patients Treated in Tertiary Care Hospitals between 2003 – 2016
Publication date: Available online 10 November 2018Source: Journal of Hospital InfectionAuthor(s): Sebastian M. Heimann, Maria J.G.T. Vehreschild, Oliver A. Cornely, Werner J. Heinz, Beate Grüner, Gerda Silling, Johanna Kessel, Danila Seidel, Jörg Janne VehreschildAbstractBackgroundInvasive mucormycosis (IM) is a rare invasive fungal infection with high mortality rates. However, data concerning the clinical and economic burden of IM are scarce.AimTo evaluate the direct treatment costs and additional expenditures of patients with IM.MethodsWe performed a retrospective cost-of-illness analysis of cases with IM extr...
Source: Journal of Hospital Infection - November 11, 2018 Category: Infectious Diseases Source Type: research

Surgical instruments complex design as barrier for cleaning effectiveness, favouring biofilm formation
ConclusionSoil and/or biofilms were evident on complex-design RSI following 20 cycles of contamination and reprocessing, even using the gold standard method of cleaning. Although the depth gauges could be disassembled, biological residues and biofilm accumulated in its lumen. The current design of these RSI prevents removal of all biological soil and this may have an adverse effect on patient outcome. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 11, 2018 Category: Infectious Diseases Source Type: research

Factors that impact on the burden of Escherichia coli bacteraemia: Multivariable regression analysis of 2011-2015 data from West London
ConclusionsMultidrug resistance, increased age, and comorbidities were the main drivers of adverse outcome. The overall incidence of E. coli bacteraemia and the incidence of cases that were antibiotic-resistant increased over time. The increase in bacteraemia was predominantly driven by an increase in community-onset infections, and initiatives aimed at prevention of these cases should be a major focus for attempts to reduce the quantitative burden of E. coli infection. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 6, 2018 Category: Infectious Diseases Source Type: research

In-house validation of the cobas Liat Influenza A/B & RSV assay for use with gargles, sputa and endotracheal secretions
Publication date: Available online 5 November 2018Source: Journal of Hospital InfectionAuthor(s): Emily Jane Goldstein, Rory N. Gunson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 6, 2018 Category: Infectious Diseases Source Type: research

Reduction of Nosocomial Blood Stream infections and Nosocomial Vancomycin Resistant Enterococcus faecium on an Intensive Care Unit After Introduction of Antiseptic Octenidine-based Bathing
ConclusionThe epidemiology of emerging VRE appeared as a complex mix of admitted cases and transmissions in small clusters, challenging infection control measures. The implementation of universal octenidine-based bathing combined with a standardised washing regime led to a significant reduction of nosocomial VRE. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 6, 2018 Category: Infectious Diseases Source Type: research

Successful control of the first OXA-48 and/or NDM carbapenemase-producing Klebsiella pneumoniae outbreak in Slovenia 2014–2016
ConclusionInitial standard control measures failed to prevent the outbreak. Once the problem had been recognized, strict infection control measures and the education of healthcare workers contributed to the successful control of the outbreak. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 4, 2018 Category: Infectious Diseases Source Type: research

Effects of the application of Vitamin E and silicone dressings vs Conventional dressings on incisional surgical site infection in elective laparoscopic colorectal surgery: A prospective randomized clinical trial
Publication date: Available online 3 November 2018Source: Journal of Hospital InfectionAuthor(s): Jaime Ruiz-Tovar, Carolina Llavero, Mercedes Perez-Lopez, Andres Garcia-MarinAbstractIntroductionThe aim of this study was to evaluate the effect on incisional surgical site infection (SSI) of conventional wound dressing vs vitamin E-silicone dressing in patients undergoing elective colorectal laparoscopic surgery.Patients and MethodsA prospective, randomized study was performed. Patients were randomly assigned into 2 groups: those patients undergoing a vitamin E-silicone containing dressing (E-Sil) and those using a conventio...
Source: Journal of Hospital Infection - November 3, 2018 Category: Infectious Diseases Source Type: research

Control strategy for carbapenemase-producing Enterobacteriaceae in nursing homes: Perspectives inspired from three outbreaks
Publication date: Available online 30 October 2018Source: Journal of Hospital InfectionAuthor(s): C. Legeay, R. Hue, C. Berton, H. Cormier, R. Chenouard, S. Corvec, G. BirgandSummaryThree outbreaks of carbapenemase-producing Enterobacteriaceae (CPE) in three nursing homes in western France were retrospectively assessed. In all, ten cases of colonization or infection with CPE were detected upon admission in neighbouring hospitals. Antibiotic consumption or high frailty was infrequent among them. Nursing homes should be included in a regional strategy to limit CPE spread. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 31, 2018 Category: Infectious Diseases Source Type: research