Association between excreta management and incidence of extended-spectrum β-lactamase-producing Enterobacteriaceae: role of healthcare workers' knowledge and practices
ConclusionsA positive correlation was found between HCWs' practices for managing excreta and the incidence of ESBL-PE, especially in surgical units. There is an urgent need for development of public health efforts to enhance knowledge and practices of HCWs to better control the spread of multi-drug-resistant bacteria, and these should be integrated within infection control programmes. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 12, 2019 Category: Infectious Diseases Source Type: research

Vancomycin use in surrounding patients during critical illness and risk for persistent colonization with vancomycin-resistant Enterococcus
Publication date: Available online 11 January 2019Source: Journal of Hospital InfectionAuthor(s): Philip Zachariah, Daniel E. FreedbergAbstractThe optimal duration of contact precautions for vancomycin-resistant enterococcus (VRE) colonized patients is uncertain and individual patient characteristics alone may not predict risk of prolonged colonization. Using a cohort of adult patients who underwent testing for VRE at intensive care unit (ICU) admission we tested the association between local (unit-level) vancomycin use and persistent colonization with VRE. Higher unit-level vancomycin use significantly prolonged VRE colon...
Source: Journal of Hospital Infection - January 12, 2019 Category: Infectious Diseases Source Type: research

An evaluation of the electronic reporting system for the enhanced surveillance of carbapenemase-producing Gram-negative bacteria in England
ConclusionThe ERS is the only surveillance system in England with the potential to gather intelligence on important risk factors for CPGNB to inform public health measures to control their spread. Although the ERS captures more information on CPGNB than other surveillance systems, timeliness and completeness of the enhanced data require substantial improvements in order to deliver the desired health benefits. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 12, 2019 Category: Infectious Diseases Source Type: research

Letter to the Editor
Publication date: Available online 12 January 2019Source: Journal of Hospital InfectionAuthor(s): Katie Prescott, Nikunj Mahida, Tim Boswell (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 12, 2019 Category: Infectious Diseases Source Type: research

Impact of penicillin allergy records on carbapenem prescribing: an observational retrospective cohort study
This study measured the impact of penicillin allergy labels on meropenem prescribing. Rates of meropenem prescribing were compared between patients with a penicillin allergy record and patients without such a record. Potential confounders were also collected (i.e. age, sex and co-morbidities). Of the 21,272 patients with no penicillin allergy, 225 (1.06%) were prescribed meropenem, whereas of the 3443 patients with penicillin allergy, 240 (6.97%) were prescribed meropenem. Meropenem prescribing is associated with a patient's penicillin allergy record. Given that many penicillin allergy records are incorrect, addressing spu...
Source: Journal of Hospital Infection - January 11, 2019 Category: Infectious Diseases Source Type: research

Effects of a disinfection device on colonization of sink-drains and patients during a prolonged outbreak with multiresistant Pseudomonas aeruginosa in an ICU
Publication date: Available online 9 January 2019Source: Journal of Hospital InfectionAuthor(s): E. de Jonge, M.G.J. de Boer, E.H.R. van Essen, H.C.M. Dogterom-Ballering, K.E. VeldkampAbstractBackground and aimSink drains in intensive care units are frequently colonized with bacteria such as Pseudomonas aeruginosa. We studied the influence of installing disinfecting devices on sink drains on colonization of sinks and patients in an ICU during a prolonged outbreak of multiresistant P. aeruginosa.MethodsFrom 2010, there was a clonal outbreak of a multidrug resistant P. aeruginosa, (MDR-PA). In April 2013, in ICU subunit A, t...
Source: Journal of Hospital Infection - January 10, 2019 Category: Infectious Diseases Source Type: research

Water-borne infections and warming the sterile water for washing high risk infants on neonatal intensive care units
Publication date: Available online 9 January 2019Source: Journal of Hospital InfectionAuthor(s): B. Cherian, E. Price (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 10, 2019 Category: Infectious Diseases Source Type: research

Detection of Hepatitis C virus in an exhumed body identifies the origin of a nosocomial transmission which caused multiple fatal diseases
ConclusionsThis study highlights the value of sequence analysis as a tool for solving medico-legal conflicts. The high court of justice sentenced that a health worker's reuse of a contaminated needle resulted in the nosocomial transmission of HCV. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 9, 2019 Category: Infectious Diseases Source Type: research

Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
Publication date: Available online 16 December 2018Source: Journal of Hospital InfectionAuthor(s): J. Youngs, Y. Iqbal, S. Glass, P. Riley, C. Pope, T. Planche, D. CarringtonSummaryThe cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21st January 2018 to 14th April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in 149 (14.5%) and RSV in 28 (2.7%). When compared against Fast Track Diagnostics Respiratory Pathogens 21 multiplex polymerase chain reaction and Ceph...
Source: Journal of Hospital Infection - January 8, 2019 Category: Infectious Diseases Source Type: research

Nosocomial Mycobacterium tuberculosis transmission by brief casual contact identified using comparative genomics
We report a case of nosocomial transmission of Mycobacterium tuberculosis by brief casual contact. Through routine variable-number tandem-repeat typing in Yamagata Prefecture, Japan, we found that M. tuberculosis clinical isolates from two patients showed indistinguishable genotypes. The patients had an epidemiological relationship of sharing a waiting room in a hospital on the same day. Since comparative genomics detected only two single-nucleotide variants between the isolates, we concluded that recent tuberculosis transmission occurred in the waiting room. These results indicate that the physical separation of infectiou...
Source: Journal of Hospital Infection - January 8, 2019 Category: Infectious Diseases Source Type: research

Nosocomial outbreak of esbl-producing enterobacter cloacae among cardio-thoracic surgical patients: causes and consequences
Publication date: Available online 7 January 2019Source: Journal of Hospital InfectionAuthor(s): A. Noël, C. Vastrade, S. Dupont, M. de Barsy, T.D. Huang, T. Van Maerken, I. Leroux-Roels, B. Delaere, L. Melly, B. Rondelet, C. Dransart, A.S. Dincq, I. Michaux, P. Bogaerts, Y. GlupczynskiAbstractBackgroundEnterobacteriaceae are recognized as leading pathogens of healthcare-associated infections. This is a report describing an investigation of a nosocomial outbreak of extended-spectrum ß-lactamase producing Enterobacter cloacae affecting cardio-thoracic surgery patients in a Belgian academic hospital.MethodsCases w...
Source: Journal of Hospital Infection - January 8, 2019 Category: Infectious Diseases Source Type: research

Prevention of healthcare-associated invasive aspergillosis during hospital construction/renovation works
Publication date: Available online 7 January 2019Source: Journal of Hospital InfectionAuthor(s): Alida Fe Talento, Margaret Fitzgerald, Brendan Redington, Niamh O’Sullivan, Lynda Fenelon, Thomas R. RogersSummaryThe association between healthcare associated invasive aspergillosis and hospital construction/building works is well recognized. This infection can cause significant morbidity and mortality and imposes a substantial burden on the healthcare system. The population of patients at-risk for this opportunistic infection has expanded and multi-triazole drug resistance has emerged globally. Therefore there is a need...
Source: Journal of Hospital Infection - January 7, 2019 Category: Infectious Diseases Source Type: research

The effect of using Fidaxomicin on recurrent Clostridium difficile infection?
Publication date: Available online 4 January 2019Source: Journal of Hospital InfectionAuthor(s): Martin Biggs, Tariq Iqbal, Elisabeth Holden, Victoria Clewer, Mark I. GarveyAbstractFidaxomicin is a macrocyclic antibiotic licensed for treating Clostridium difficile infection (CDI). In the UK, fidaxomicin is often reserved for severe CDI or recurrences. At Queen Elizabeth Hospital Birmingham, all courses of fidaxomicin during 2017/18 were reviewed. Thirty-eight patients received fidaxomicin, of which 64% patients responded to treatment when fidaxomicin was given during the first episode of a mild CDI. Conversely, all patient...
Source: Journal of Hospital Infection - January 5, 2019 Category: Infectious Diseases Source Type: research

A quality improvement initiative for improving hospital visitor hand hygiene
Publication date: Available online 4 January 2019Source: Journal of Hospital InfectionAuthor(s): Amy T. Hummel, Karen Vleck, William B. Greenough (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 5, 2019 Category: Infectious Diseases Source Type: research

Can guidelines for the control of multi-drug resistant gram negative organisms be put into practice? A national survey of guideline compliance and comparison of available guidelines
ConclusionThis survey gives an insight into the real life applicability of HPSC guidelines. Survey results are placed in context with a comparison of 5 MDRGNO IPC guidelines. Although core tenets of IPC are standard across guidelines, research into which practices are efficient in reducing MDRGNO transmission while being cost-effective would be worthwhile. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 5, 2019 Category: Infectious Diseases Source Type: research

Implementation of influenza point-of-care testing and patient cohorting during a high-incidence season: a retrospective analysis of impact on infection prevention and control and clinical outcomes
Publication date: Available online 22 November 2018Source: Journal of Hospital InfectionAuthor(s): J. Youngs, B. Marshall, M. Farragher, L. Whitney, S. Glass, C. Pope, T. Planche, P. Riley, D. CarringtonSummaryBackgroundDuring high-incidence influenza seasons, a robust infection prevention and control policy is imperative to reduce nosocomial transmission of influenza.AimTo assess the impact of influenza point-of-care testing (POCT) in an emergency department (ED) and patient cohorting on an influenza ward on infection prevention and control and clinical outcomes.MethodsInfluenza POCT was operational in the study ED from 2...
Source: Journal of Hospital Infection - January 4, 2019 Category: Infectious Diseases Source Type: research

Overall bioburden by total colony count does not predict the presence of pathogens with high clinical relevance in hospital and community environments
ConclusionTCC poorly predicted the presence of PHCR, rendering the results from environmental sampling difficult to interpret. MALDI-TOF enables the identification of large numbers of isolates from the environment at low cost. Further studies on environmental contamination should use MALDI-TOF to identify all pathogens grown. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 3, 2019 Category: Infectious Diseases Source Type: research

Are perineal swabs required as part of initial staff screening in healthcare-associated Streptococcus pyogenes outbreaks?
Publication date: Available online 5 December 2018Source: Journal of Hospital InfectionAuthor(s): M. Meda, V. Gentry, A. Walker (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 3, 2019 Category: Infectious Diseases Source Type: research

Workplace vaccination against measles in a teaching hospital of Rome
Publication date: Available online 6 December 2018Source: Journal of Hospital InfectionAuthor(s): L. Coppeta, A. Pietroiusti, L. Morucci, A. Neri, M. Ferraro, A. Magrini (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - January 3, 2019 Category: Infectious Diseases Source Type: research

Monitoring healthcare associated infections and antimicrobial use at regional level through repeated point prevalence surveys: what can we learn
Publication date: Available online 29 December 2018Source: Journal of Hospital InfectionAuthor(s): L. Arnoldo, C. Smaniotto, D. Celotto, L. Brunelli, R. Cocconi, D. Tignonsini, A. Faruzzo, S. Brusaferro, R. Collazzo, M. Mansutti, F. Martellotta, M. Giacomini, G. Del Ben, C. Vigo, M. Marino, F. Farneti, G. Franca, L. Calligaris, C. Giuliani, R. PerossaSummaryBackgroundHealthcare associated infections (HAIs) surveillance is an essential part of any infection prevention and control programme. Repeated point prevalence surveys (PPS) according to ECDC protocol have been implemented in all Friuli Venezia Giulia (FVG) region (Ita...
Source: Journal of Hospital Infection - December 29, 2018 Category: Infectious Diseases Source Type: research

Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry
ConclusionGiven the lack of articles providing practical cleaning guidance, this review proposes a four-step protocol based on evidence if available, or justified where not. Each step is presented, discussed and risk-assessed. It is likely that a systematic cleaning process would reduce the risk of healthcare-acquired infection for everyone, including outbreaks, in addition to heightened confidence in overall quality of care. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 28, 2018 Category: Infectious Diseases Source Type: research

Acinetobacter - the Trojan Horse of infection Control?
ConclusionIn an outbreak where contact precautions and environmental cleaning are optimal, it is important to give careful consideration to other mechanisms of spread. If there is a failure to do this, it is likely that the true causes of transmission will not be addressed and the problem will recur. We recommend that burns theatres within a burn facility are designed to operate at negative pressure; this is the opposite of normal operating theatre ventilation. Where showers are used, both shower head and hose should be changed after a patient with a resistant organism. The role of non-contact disinfection (e.g. hydrogen p...
Source: Journal of Hospital Infection - December 28, 2018 Category: Infectious Diseases Source Type: research

Application of the Theoretical Domains Framework to identify factors that influence hand hygiene compliance in long-term care
ConclusionsThere are a number of barriers to hand hygiene compliance that persist in long-term care. A behaviour change theory-informed framework such as the TDF can be helpful to identify those barriers. We identified several key behavioural constructs aligned with the TDF that can be targeted when developing novel hand hygiene interventions. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 28, 2018 Category: Infectious Diseases Source Type: research

Reduction of nosocomial bloodstream infections and nosocomial vancomycin-resistant Enterococcus faecium on an intensive care unit after introduction of antiseptic octenidine-based bathing
ConclusionThe epidemiology of emerging VRE appeared as a complex mix of admitted cases and transmissions in small clusters, challenging infection control measures. The implementation of universal octenidine-based bathing combined with a standardized washing regime led to a significant reduction in nosocomial VRE. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 25, 2018 Category: Infectious Diseases Source Type: research

Identifying hospital acquired infections using retrospective record review from the Irish National Adverse Events Study (INAES) and European point prevalence survey case definitions
ConclusionRetrospective record review is an accurate source of information on HAI incidence, preventability and impact that complements PPS prevalence rates. HAI adverse events result in higher costs to the healthcare system than other adverse events. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 25, 2018 Category: Infectious Diseases Source Type: research

Food for thought. Malnutrition risk associated with increased risk of healthcare-associated infection
Publication date: Available online 25 December 2018Source: Journal of Hospital InfectionAuthor(s): F. Fitzpatrick, M. Skally, C. O’Hanlon, M. Foley, J. Houlihan, L. Gaughan, O. Smith, B. Moore, S. Cunneen, E. Sweeney, B. Dinesh, K. O’Connell, E. Smyth, H. Humphreys, K. BurnsSummaryBackgroundInfection and malnutrition are interconnected. UK and Irish guidelines recommend the Malnutrition Universal Screening Tool (MUST) for nutritional risk screening. Patients with a MUST score of ≥2 are considered at high risk of malnutrition and referral for nutritional assessment is recommended.AimTo explore the association...
Source: Journal of Hospital Infection - December 25, 2018 Category: Infectious Diseases Source Type: research

Acetic acid as a decontamination method for carbapenemase-producing Enterobacteriaceae colonized sink drains in an ICU and its effect on CPE infections
ConclusionOur method of decontaminating sink drains with acetic acid, is a valuable alternative to other methods like heated sinks and water-free care, especially when other options are not feasible in the near term. Acetic acid is cheap, widely available, effective and manageable from a safety and technical point of view. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 21, 2018 Category: Infectious Diseases Source Type: research

Preoperative Mechanical and Oral Antibiotic Bowel Preparation to Reduce Infectious Complications of Colorectal Surgery – The Need for Updated Guidelines
ConclusionsFew UK and European colorectal surgeons use mechanical and oral antibiotic bowel preparation, despite evidence of its efficacy in reducing infectious complications. The influence of ERAS pathways and UK and European guidelines may explain this. In contradiction to the UK and Europe, North American guidelines recommend incorporating MBP/OAB, into ERAS programmes. We suggest future UK and European guidelines incorporate MBP/OABP into the ERAS pathway. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 21, 2018 Category: Infectious Diseases Source Type: research

Effect of using ceiling-mounted systems for imaging in hybrid operating rooms on the level of colony-forming units during surgery
ConclusionsA ceiling-mounted imaging system in combination with a UDF system can result in cfu levels near the surgical wound and at the instrument table that are well below the threshold value of 10 cfu/m3 during surgery. If the instrument table is not positioned directly under the UDF system, the cfu level is higher. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Bacterial load and pathogenic species on healthcare personnel attire: implications of alcohol hand-rub use, profession, and time of duty
Publication date: Available online 26 October 2018Source: Journal of Hospital InfectionAuthor(s): A. Ambrosch, K. Wahrburg, F. KlawonnSummaryBackgroundSince hand hygiene might prevent the risk of bacterial transmission from healthcare personnel attire (HCPA), the present study investigates the effect of alcohol-based hand rub (ABHR) use on bacterial load and pathogenic species on HCPA.MethodsHCPA from doctors and nurses was investigated for bacterial contamination post duty. Samples from distinct areas of HCPA were obtained and analysed for bacterial load and species. A standardized questionnaire was performed regarding ti...
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Effect of disinfectant formulation and organic soil on the efficacy of oxidizing disinfectants against biofilms
This study compared the activity of formulated oxidizing disinfectants with products containing active ingredients against Staphylococcus aureus dry-surface biofilm (DSB) alone.MethodsDSB was grown in the CDC bioreactor with alternating cycles of hydration and dehydration. Disinfectant efficacy was tested before and after treatment with neutral detergent for 30 s, and in the presence or absence of standardized soil. Biofilms were treated for 5 min with peracetic acid (Surfex and Proxitane), hydrogen peroxide (Oxivir and 6% H2O2 solution) and chlorine (Chlorclean and sodium dichloroisocyanurate tablets). Residual biofilm vi...
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Healthcare burden of probable and proven invasive mucormycosis: a multi-centre cost-of-illness analysis of patients treated in tertiary care hospitals between 2003 and 2016
Publication date: Available online 10 November 2018Source: Journal of Hospital InfectionAuthor(s): S.M. Heimann, M.J.G.T. Vehreschild, O.A. Cornely, W.J. Heinz, B. Grüner, G. Silling, J. Kessel, D. Seidel, J.J. VehreschildSummaryBackgroundInvasive mucormycosis (IM) is a rare invasive fungal infection with a high mortality rate. However, data concerning the clinical and economic burden of IM are scarce.AimTo evaluate the direct treatment costs and additional expenditures of patients with IM.MethodsA retrospective cost-of-illness analysis of cases with IM extracted from FungiScope – Global Registry for Emerging Fu...
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: January 2019Source: Journal of Hospital Infection, Volume 101, Issue 1Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Healthcare-associated infections: the hallmark of Middle East respiratory syndrome coronavirus with review of the literature
Publication date: January 2019Source: Journal of Hospital Infection, Volume 101, Issue 1Author(s): J.A. Al-Tawfiq, P.G. AuwaerterSummaryMiddle East respiratory syndrome coronavirus (MERS-CoV) is capable of causing acute respiratory illness. Laboratory-confirmed MERS-CoV cases may be asymptomatic, have mild disease, or have a life-threatening infection with a high case fatality rate. There are three patterns of transmission: sporadic community cases from presumed non-human exposure, family clusters arising from contact with an infected family index case, and healthcare-acquired infections among patients and from patients to...
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Establishing nationally representative central line-associated bloodstream infection surveillance data for paediatric patients in Greece
ConclusionNationally representative CLABSI rates were determined for paediatric patients. These data could be used to benchmark and serve as baseline data for the design and evaluation of infection control and antimicrobial stewardship interventions. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Multi-centre point-prevalence survey of hospital-acquired infections in Ghana
ConclusionA low HAI burden was found compared with findings from other low- and middle-income countries. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Bacteriology and cefuroxime resistance in endophthalmitis following cataract surgery before and after the introduction of prophylactic intracameral cefuroxime: a retrospective single-centre study
Publication date: January 2019Source: Journal of Hospital Infection, Volume 101, Issue 1Author(s): E. Friling, P. MontanSummaryBackgroundIntracameral cefuroxime as prophylaxis against postoperative endophthalmitis (POE) following cataract surgery was introduced in 1996 at St Erik Eye Hospital. Soon after the introduction of intracameral cefuroxime, the rate of POE fell dramatically and a shift in the aetiology was noticed.AimTo analyse bacteriology and susceptibility to cefuroxime before and after the introduction of intracameral cefuroxime.MethodsAll culture-proven cases of endophthalmitis at St Erik Eye Hospital after ca...
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Sepsis programme successes are responsible for the increased detection of bacteraemia
ConclusionSuccess in one area (sepsis management) conflicts with ‘failure’ in reducing E. coli bacteraemia. It is argued that targets need to be considered carefully in the light of all available information, which have currently set the National Health Service up to fail. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 20, 2018 Category: Infectious Diseases Source Type: research

Broad-spectrum antibiotic prescriptions are discontinued unevenly throughout the week
This study suggests that broad-spectrum antibiotics tend to be continued over weekends or holidays and discontinued thereafter; this is likely to be due to behavioural factors beyond medical indications, and needs to be addressed in future antimicrobial stewardship initiatives. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 18, 2018 Category: Infectious Diseases Source Type: research

Observation study of water outlet design from a cross-infection/user perspective: time for a radical re-think?
ConclusionsAlthough handwashing is a key barrier to cross-infection, poor selection and incorrect use of outlet undermines its effectiveness. Design and incorrect instalment further compromise the intended means of operation of elbow levers. Of equal concern is that this risk mostly goes unrecognized. There is an opportunity to improve handwashing safety, but it requires engagement across a broad stratum from Government Departments of Health and manufacturers down to the user. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 18, 2018 Category: Infectious Diseases Source Type: research

Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system
Publication date: Available online 18 December 2018Source: Journal of Hospital InfectionAuthor(s): P. Aranega Bou, R.P. George, N.Q. Verlander, S. Paton, A. Bennett, G. Moore, TRACE Investigators‘ GroupSummaryBackgroundHospital sinks, waste traps and drains can harbour carbapenem-resistant Enterobacteriaceae (CRE).AimTo investigate the dispersal of CRE from sinks in which water delivered from the tap flows directly into the drain and from clinical handwash basins with the drain at the rear. The effect of fast and slow drainage rates was also assessed.MethodsWaste traps, known to be colonised with CRE, were taken from...
Source: Journal of Hospital Infection - December 18, 2018 Category: Infectious Diseases Source Type: research

Implementation of the cobas® Liat® influenza point-of-care-test into an Emergency Department during a high-incidence season: a retrospective evaluation following real-world implementation
Publication date: Available online 16 December 2018Source: Journal of Hospital InfectionAuthor(s): Jonathan Youngs, Yasser Iqbal, Stephen Glass, Peter Riley, Cassie Pope, Timothy Planche, David CarringtonSummaryThe cobas® Liat® influenza A/B & RSV assay (Liat) was used in the adult Emergency Department of a large London Hospital from 21/1/18-14/4/18. Influenza was detected in 308/1027 (30%) of samples tested; influenza A in 157 (15.3%) and influenza B in 149 (14.5%) and RSV in 28 (2.7%). When compared against Fast Track Diagnostics Respiratory Pathogens 21 multiplex PCR and Cepheid Xpert® Xpress Flu/RSV ass...
Source: Journal of Hospital Infection - December 16, 2018 Category: Infectious Diseases Source Type: research

Association between excreta management and extended-spectrum β-lactamase producing Enterobacteriaceae incidence rate: Role of health-care worker’s knowledge and practices
ConclusionsHCWs’ practices for managing excreta positively correlated with ESBL-PE incidence, especially in surgical units. Public health efforts to enhance knowledge and practices of HCWs urgently need to be developed and integrated, within infection control programs, to better control the spread of multidrug-resistant bacteria. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 15, 2018 Category: Infectious Diseases Source Type: research

What are the main drivers for public policies to prevent healthcare-associated infections?
Publication date: Available online 13 December 2018Source: Journal of Hospital InfectionAuthor(s): Maria Clara Padoveze, Cassimiro Nogueira, Judith Tanner, Stephen Timmons (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 14, 2018 Category: Infectious Diseases Source Type: research

Staphylococcus aureus meningitis in adults: A comparative cohort study of infections caused by meticillin-resistant and meticillin-susceptible strains
Publication date: Available online 16 November 2018Source: Journal of Hospital InfectionAuthor(s): V. Pintado, R. Pazos, M.E. Jiménez-Mejías, A. Rodríguez-Guardado, B. Díaz-Pollán, C. Cabellos, J.M. García-Lechuz, J. Lora-Tamayo, P. Domingo, E. Muñez, D. Domingo, F. González-Romo, J.A. Lepe-Jiménez, C. Rodríguez-Lucas, A. Gil, I. Pelegrín, F. Chaves, V. Pomar, A. Ramos, T. AlarcónSummaryBackgroundStaphylococcus aureus meningitis is an uncommon nosocomial infection usually associated with neurosurgical procedures, but spontaneous infections ...
Source: Journal of Hospital Infection - December 13, 2018 Category: Infectious Diseases Source Type: research

Preventing healthcare-associated infection by sharing research, evidence and best practice
Publication date: Available online 12 December 2018Source: Journal of Hospital InfectionAuthor(s): J. Gray, G. Winzor, N. Mahdia, B. Oppenheim, A. Johnston (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 12, 2018 Category: Infectious Diseases Source Type: research

Analysis of awareness and knowledge about Mycobacterium chimaera invasive infections among doctors and medical students
Publication date: Available online 10 December 2018Source: Journal of Hospital InfectionAuthor(s): Y. Ortiz-Martínez, C. Galindo-Regino, E. Salcedo-Rodríguez, H.J. Rojas-Moreno, M.L. Beltrán-Avilez (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 11, 2018 Category: Infectious Diseases Source Type: research

The method used to dry washed hands affects the number and type of transient and residential bacteria remaining on the skin
Publication date: Available online 8 December 2018Source: Journal of Hospital InfectionAuthor(s): Reinier Mutters, Sarah L. WarnesSummaryBackgroundWidespread antibiotic resistance has led to fears that we are entering a pre-antibiotic era and the relatively simple premise of hand washing to reduce transfer of bacteria and viruses has never been more important. Much of the emphasis has been on handwashing technique, type of soap and maintaining compliance but effective drying of the hands is just as important.AimTo compare the efficacy of drying washed hands with a jet air dryer or paper towels to remove transient bacterial...
Source: Journal of Hospital Infection - December 9, 2018 Category: Infectious Diseases Source Type: research

In-house validation of the cobas Liat influenza A/B and RSV assay for use with gargles, sputa and endotracheal secretions
Publication date: Available online 5 November 2018Source: Journal of Hospital InfectionAuthor(s): E.J. Goldstein, R.N. Gunson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 8, 2018 Category: Infectious Diseases Source Type: research

Complex design of surgical instruments as barrier for cleaning effectiveness, favouring biofilm formation
ConclusionSoil and/or biofilms were evident on complex-design RSIs following 20 cycles of contamination and reprocessing, even using the reference standard method of cleaning. Although the depth gauges could be disassembled, biological residues and biofilm accumulated in its lumen. The current design of these RSIs prevents removal of all biological soil and this may have an adverse effect on patient outcome. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - December 8, 2018 Category: Infectious Diseases Source Type: research