Residual effect of community antimicrobial exposure on risk of hospital onset healthcare-associated Clostridioides difficile infection: a case–control study using national linked data
ConclusionsCommunity antimicrobial exposure is an independent risk factor for HA-CDI and should be considered as part of the risk assessment of patients developing diarrhoea in hospital. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 10, 2019 Category: Infectious Diseases Source Type: research

Incremental clinical and economic burden of suspected respiratory infections due to multi-drug-resistant Pseudomonas aeruginosa in the United States
This study analyzed electronically captured microbiological and outcomes data of patients hospitalized with non-duplicate P. aeruginosa isolates from respiratory sources collected ≥3 days after admission to identify hospital-onset MDR or non-MDR P. aeruginosa per the Centers for Disease Control and Prevention definition. The risk of multi-drug resistance was estimated on mortality, length of stay (LOS), cost, operation gain/loss, and 30-day readmission. A sensitivity analysis was conducted utilizing a cohort with pharmacy data available.FindingsOf 523 MDR and 1381 non-MDR P. aeruginosa cases, unadjusted m...
Source: Journal of Hospital Infection - July 10, 2019 Category: Infectious Diseases Source Type: research

A survey to quantify wet loads after steam sterilization processes in healthcare facilities
Publication date: Available online 24 May 2019Source: Journal of Hospital InfectionAuthor(s): J.P.C.M. van Doornmalen, F. Tessarolo, N. Lapanaitis, K. Henrotin, A. Inglese, H.W. Oussoren, R. Queiroz de SouzaSummaryWet loads after steam sterilization of medical devices in healthcare facilities are unacceptable. However, little is known about their frequency in daily practice. An online survey was distributed via four national sterilization associations, in Australia (Sterilising Research Advisory Council of Australia (Vic), Inc. (VIC SRACA)), Belgium (Vereniging sterilisatie in het ziekenhuis (VSZ)), Italy (Associazione Ita...
Source: Journal of Hospital Infection - July 7, 2019 Category: Infectious Diseases Source Type: research

Seasonal respiratory virus testing in management of adult cystic fibrosis patients
Publication date: Available online 4 July 2019Source: Journal of Hospital InfectionAuthor(s): Sapna Gohil, Bernadette Donaghy, Darren Tature, Julia Kowal, Sarah Lea, Florence YL. Lai, Simon Range, Julian W. Tang (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

Can Real-Time PCR Allow a Faster Recovery of Hospital Activity in Cases of an Incidental Discovery of Carbapenemase-Producing Enterobacteriaceae and Vancomycin-Resistant Enterococci Carriers?
ConclusionsRT-PCR (GeneXpert®) can avoid three weekly rectal samplings needed to rule-out acquisition of CPE/VRE. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

The difficulty in removing biofilms from dry surfaces
This report demonstrates that a Staphylococcus aureus biofilm is significantly harder to remove than dried planktonic bacteria. A single wipe removed>99.9% (>3Log10) of dried planktonic bacteria, whereas only 1.48Log10 of biofilm (96.66%) was removed by a standardised wiping process after 50 wipes. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

Indoor hospital air and the impact of ventilation on bioaerosols: a systematic review
Publication date: Available online 4 July 2019Source: Journal of Hospital InfectionAuthor(s): Rebecca E. Stockwell, Emma L. Ballard, Peter O’Rourke, Luke D. Knibbs, Lidia Morawska, Scott C. BellSummaryHospital-acquired infections (HAI) continue to persist in hospitals, despite the use of increasingly strict infection control precautions. Opportunistic airborne transmission of potentially pathogenic bioaerosols may be one possible reason for this persistence. Therefore, we aimed to systematically review the concentrations and compositions of indoor bioaerosols in different areas within hospitals and the effects of dif...
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

Challenges remain for nosocomial infection control in China
Publication date: Available online 4 July 2019Source: Journal of Hospital InfectionAuthor(s): Chuanxi Fu, Ruiheng Xu (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

Real-time whole genome sequencing to control a Streptococcus pyogenes outbreak at a national orthopaedic hospital
ConclusionThe increased molecular discrimination of WGS confirmed the clustering of these cases and the outbreak was contained. This demonstrates the clinical utility of WGS in managing outbreaks of invasive Streptococcus pyogenes in real-time and we recommend its implementation as a routine clinical service. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 5, 2019 Category: Infectious Diseases Source Type: research

Variations in antibiotic use across India: multi-centre study through Global Point Prevalence survey
Publication date: Available online 3 June 2019Source: Journal of Hospital InfectionAuthor(s): S.K. Singh, S. Sengupta, R. Antony, S. Bhattacharya, C. Mukhopadhyay, V. Ramasubramanian, A. Sharma, S. Sahu, S. Nirkhiwale, S. Gupta, A. Rohit, S. Sharma, V. Raghavan, P. Barman, S. Sood, D. Mamtora, S. Rengaswamy, A. Arora, H. Goossens, A. VersportenSummaryThe aim of the study was to assess antimicrobial prescribing patterns, and variation in practice, in India. A point prevalence survey (PPS) was conducted in October to December 2017 in 16 tertiary care hospitals across India. The survey included all inpatients receiving an ant...
Source: Journal of Hospital Infection - July 4, 2019 Category: Infectious Diseases Source Type: research

Evaluation of droplet production by a new design of clinical hand wash basin for the healthcare environment
Publication date: Available online 3 July 2019Source: Journal of Hospital InfectionAuthor(s): Samuel Yui, Monika Muzslay, Kush Karia, Bronwen Shuttleworth, Shanom Ali, Natalia Dudzinska, Peter WilsonSummarySplashing from handwash basins may be a source of bacteria in the healthcare environment. A novel splash-reducing basin was assessed for its ability to reduce droplet formation during simulated handwashing. The basin was compared to two conventional basins commonly used in healthcare. Basins were mounted in a test system and tap flushed for 30 seconds with and without handwashing. Droplets were visualised with fluorescen...
Source: Journal of Hospital Infection - July 4, 2019 Category: Infectious Diseases Source Type: research

An outbreak of meticillin-resistant Staphylococcus aureus colonization in a neonatal intensive care unit: use of a case–control study to investigate and control it and lessons learnt
ConclusionsLack of accurate recording of which nurses looked after which infants (and when) made identification of the risk posed by being cared for by particular nurses difficult. If this had been clearer, it may have enabled earlier identification of the colonized nurse, avoiding subsequent cases. This study highlights the benefit of using a case–control study, which showed that most nurses had no association with colonized infants. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 2, 2019 Category: Infectious Diseases Source Type: research

Prevalence and incidence of surgical site infections in the European Union/European Economic Area: how do these measures relate?
ConclusionDue to a lack of accuracy, we recommend using PPS data to estimate SSI incidence only in situations where incidence surveillance of SSIs is not performed, and sufficiently large samples of PPS data are available. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 1, 2019 Category: Infectious Diseases Source Type: research

Epidemiology and health-economic burden of urinary-catheter-associated infection in English NHS hospitals: a probabilistic modelling study
ConclusionsHospital catheter prevention is poised to reap substantial health-economic gains, but community-oriented interventions are needed to target the large burden imposed by community-onset infection. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 29, 2019 Category: Infectious Diseases Source Type: research

Escherichia coli bloodstream infection outcomes and preventability: a six-month prospective observational study
ConclusionsE. coli BSI has an appreciable mortality, with little in the way of modifiable risk factors for mortality or prolonged hospital stay. Attention to urinary catheter use is likely to be the most useful way to reduce the incidence, but current UK reduction targets may be unachievable. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 29, 2019 Category: Infectious Diseases Source Type: research

Preventing hospital onset Escherichia coli bacteraemias: Is hydration the solution?
Publication date: Available online 28 June 2019Source: Journal of Hospital InfectionAuthor(s): Rodric Vian Francis, Tim C. Boswell, Nikunj Mahida (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 29, 2019 Category: Infectious Diseases Source Type: research

The Impact of Dispatching Infectious Diseases Physicians for Infection Control. Interrupted Time Series Analysis (ITSA) on Carbapenem Use and Blood Cultures
Publication date: Available online 26 June 2019Source: Journal of Hospital InfectionAuthor(s): Kentaro Iwata, Naomi Morishita, Yoshimi Sakai, Kazuhisa Doimoto, Masami Nishiwaki (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 26, 2019 Category: Infectious Diseases Source Type: research

A new approach to put isolation precaution guidelines into practice
Publication date: Available online 29 May 2019Source: Journal of Hospital InfectionAuthor(s): B. Olesen, I. Ulriksen, M. Kreiner-Moeller, D. Tomsen, A.-M. Thye (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 25, 2019 Category: Infectious Diseases Source Type: research

The Healthcare Environment and Infection
Publication date: Available online 21 June 2019Source: Journal of Hospital InfectionAuthor(s): James Gray, Phil Orton (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 22, 2019 Category: Infectious Diseases Source Type: research

Impact of a checklist used by pharmacists on hospital antimicrobial use: A patient-level interrupted time series study
ConclusionAn antimicrobial checklist used by ward-based clinical pharmacists did not decreased DOT for all antimicrobials, but decreased DOT-ES and LOT upon its implementation. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 22, 2019 Category: Infectious Diseases Source Type: research

Epidemiology and impact of norovirus outbreaks in Norwegian healthcare institutions, 2005-2018
ConclusionsNorovirus outbreaks in Norwegian HCIs appears to have a substantial impact both hospital and LTCFs all over Norway, especially during the winter months. That up to half of of all cases were healthcare professionals emphasizes is a need for further focus on infection control. Our results suggest that hospitals, affected first, could alert LTCFs in the area in order to prevent further outbreaks. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 22, 2019 Category: Infectious Diseases Source Type: research

Candida auris associated outbreak report from Pakistan: a success story of infection control in ICU of a tertiary care hospital
Publication date: Available online 22 June 2019Source: Journal of Hospital InfectionAuthor(s): Fatima Sana, Wajid Hussain, Gohar Zaman, LuqmanSatti, UmerKhurshid, Muhammad Tahir Khadim (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 22, 2019 Category: Infectious Diseases Source Type: research

‘Off the Rails’: Hospital bed rail design, contamination, and the evaluation of their microbial ecology
This report reviews the evolving structure of hospital beds and bed rails, the possible impact of different design elements on microbial contamination and their role in pathogen transmission. Our findings support the need for clearly defined standardized assessment protocols to accurately assess bedrail and similar patient zone surfaces levels of contamination, as part of environmental hygiene investigations. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 22, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: July 2019Source: Journal of Hospital Infection, Volume 102, Issue 3Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 20, 2019 Category: Infectious Diseases Source Type: research

Ex vivo and in vivo evaluation of residual chlorhexidine gluconate on skin following repetitive exposure to saline and wiping with 2% chlorhexidine gluconate/70% isopropyl alcohol pre-operative skin preparations
ConclusionsThe addition of a film-forming copolymer has the potential to improve the retention of CHG on skin throughout a surgical procedure compared to a water-soluble preparation. This improved retention may lead to better antimicrobial activity. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 20, 2019 Category: Infectious Diseases Source Type: research

Gloved hand disinfection improved hand hygiene before infection prone procedures on a stem cell ward
Publication date: Available online 18 June 2019Source: Journal of Hospital InfectionAuthor(s): Patrick (P) Fehling, Justin (J) Hasenkamp, Steffen (S) Unkel, Ina (I) Thalmann, Sandra (S) Hornig, Lorenz (L) Trümper, Simone (S) ScheithauerSummaryBackgroundHand hygiene compliance even before infection prone procedures (indication 2, “before aseptic tasks”, according to WHO) remains disappointing. The aim of this study was to improve hand hygiene compliance by implementing gloved hand disinfection as a resource-neutral process optimization strategy.MethodsWe performed a three-phase intervention study on a stem ...
Source: Journal of Hospital Infection - June 19, 2019 Category: Infectious Diseases Source Type: research

Incremental Clinical and Economic Burden of Suspected Respiratory Infections due to Multidrug-Resistant Pseudomonas aeruginosa in the United States
Publication date: Available online 19 June 2019Source: Journal of Hospital InfectionAuthor(s): Ying P. Tabak, Sanjay Merchant, Gang Ye, Latha Vankeepuram, Vikas Gupta, Stephen G. Kurtz, Laura A. PuzniakSummaryBackgroundMultidrug resistant (MDR) Pseudomonas aeruginosa can negatively affect patients and hospitals.AimTo evaluate excess mortality and cost burden among patients hospitalized with suspected respiratory infections due to MDR P. aeruginosa versus patients with non-MDR P. aeruginosa in 78 United States (US) hospitals.MethodsWe analyzed electronically captured microbiological and outcomes data of patients hospitalize...
Source: Journal of Hospital Infection - June 19, 2019 Category: Infectious Diseases Source Type: research

Candida auris outbreak on a vascular ward – the unexpected arrival of an anticipated pathogen
Publication date: Available online 17 June 2019Source: Journal of Hospital InfectionAuthor(s): C. O'Connor, T. Bicanic, J. Dave, T.J. Evans, P. Moxey, U. Adamu, D. Shakespeare, M. Cotter (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 18, 2019 Category: Infectious Diseases Source Type: research

Two year analysis of Clostridium difficile ribotypes associated with increased severity
ConclusionsA wide range of C. difficile ribotypes were responsible for C. difficile infection presentations. Although C. difficile-associated mortality has reduced in recent years, expansion of lineages associated with increased severity could herald increases in future mortality. Enhanced surveillance for emerging lineages such as RT220 that are associated with more severe disease is required, with genomic approaches to dissect pathogenicity. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 18, 2019 Category: Infectious Diseases Source Type: research

Candida auris exhibits resilient biofilm characteristics in vitro: implications for environmental persistence
Publication date: Available online 18 June 2019Source: Journal of Hospital InfectionAuthor(s): Bryn Short, Jason Brown, Christopher Delaney, Leighann Sherry, Craig Williams, Gordon Ramage, Ryan KeanAbstractSurfaces within healthcare play a key role in the transmission of drug-resistant pathogens. Candida auris is an emerging multi-drug resistant yeast which has the ability to survive for prolonged periods on environmental surfaces. Here we show that the ability to form cellular aggregates increases survival after 14 days, which coincides with the upregulation of biofilm-associated genes. Additionally, the aggregating strai...
Source: Journal of Hospital Infection - June 18, 2019 Category: Infectious Diseases Source Type: research

Tracking Staphylococcus aureus in the intensive care unit using whole-genome sequencing
This study utilized known staphylococcal epidemiology to track S. aureus between different ecological reservoirs in one 10-bed intensive care unit (ICU).MethodsSelected hand-touch surfaces, staff hands and air were screened systematically 10 times during 10 months, with patients screened throughout the study. S. aureus isolates were subjected to spa typing and epidemiological analyses, followed by whole-genome sequencing to provide single nucleotide polymorphism (SNP) data.ResultsMultiple transmission pathways between patients and reservoirs were investigated. There were 34 transmission events, of which 29 were highly related (
Source: Journal of Hospital Infection - June 17, 2019 Category: Infectious Diseases Source Type: research

Effects of prophylactic use of taurolidine-citrate lock on the number of catheter-related infections in children under 2 years of age undergoing surgery
Publication date: Available online 2 May 2019Source: Journal of Hospital InfectionAuthor(s): M. Łyszkowska, G. Kowalewski, M. Szymczak, D. Polnik, A. Mikołajczyk, P. KalicińskiSummaryCentral venous access poses a risk for the development of catheter-related infections (CRIs). The aim of this study was to evaluate prophylactic use of taurolidine-citrate (T-C) solution on the number of CRIs. Ninety-seven catheters, used in 86 children, were divided at random into two groups: Group T(-) (N=49) underwent standard aseptic procedures, and Group T(+) (N=48) received additional filling of the lines with T-C solution during inte...
Source: Journal of Hospital Infection - June 16, 2019 Category: Infectious Diseases Source Type: research

Managing seasonal influenza in hospitalized patients – without an influenza point-of-care test
Publication date: Available online 21 May 2019Source: Journal of Hospital InfectionAuthor(s): G. Hills, M. Kennedy, O. Ahmed, J.W. Tang (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 16, 2019 Category: Infectious Diseases Source Type: research

Molecular epidemiology study of a nosocomial Moraxella catarrhalis outbreak in a neurological rehabilitation unit
ConclusionThe first M. catarrhalis outbreak involving nine patients of a neurological and trauma rehabilitation centre was reported. Potential transmission pathways were discussed. Comprehensive outbreak analyses insinuated the extension of routine laboratory storage time for defined species. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 14, 2019 Category: Infectious Diseases Source Type: research

Interlaboratory reproducibility of a test method following four-field test methodology to evaluate the susceptibility of Clostridium difficile spores
Publication date: Available online 12 June 2019Source: Journal of Hospital InfectionAuthor(s): Stefanie Gemein, Jürgen Gebel, Bärbel Christiansen, Heike Martiny, Lutz Vossebein, Florian H.H. Brill, Maja Decius, Maren Eggers, Torsten Koburger-Janssen, Maren Meckel, Sebastian Werner, Birgit Hunsinger, Thomas Selhorst, Günter Kampf, Martin ExnerSummarySporicidal surface disinfection is recommended to control transmission of Clostridium difficile in healthcare facilities. EN 17126 provides a method to determine the sporicidal activity in suspension and has been approved as a European standard. In addition, a spo...
Source: Journal of Hospital Infection - June 14, 2019 Category: Infectious Diseases Source Type: research

Interlaboratory reproducibility of a test method following 4-field test methodology to evaluate the susceptibility of Clostridium difficile spores
Publication date: Available online 12 June 2019Source: Journal of Hospital InfectionAuthor(s): Stefanie Gemein, Jürgen Gebel, Katrin Steinhauer, Bärbel Christiansen, Heike Martiny, Bernhard Meyer, Christiane Ostermeyer, Hans-Joachim Rödger, Lutz Vossebein, Lars Paßvogel, Florian H.H. Brill, Maja Decius, Maren Eggers, Torsten Koburger-Janssen, Maren Meckel, Heike Vogelsang, Sebastian Werner, Birgit Hunsinger, Thomas Selhorst, Günter KampfSummarySporicidal surface disinfection is recommended to control transmission of Clostridium difficile in healthcare facilities. EN 17126 provides a method to dete...
Source: Journal of Hospital Infection - June 13, 2019 Category: Infectious Diseases Source Type: research

Analysis of Acinetobacter baumannii survival in liquid media and on solid matrices as well as effect of disinfectants
ConclusionThe ability to persist for long periods on different surfaces, mimicking those usually found in hospitals, along with A. baumannii's capacity to survive after a disinfection process may account for the recurrent outbreaks in intensive care units. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 9, 2019 Category: Infectious Diseases Source Type: research

Dissemination of NDM-1 carbapenemase-producer Providencia stuartii strains in Romanian hospitals: a multicentre study
Publication date: Available online 27 April 2019Source: Journal of Hospital InfectionAuthor(s): S. Molnár, M.M.M. Flonta, A. Almaş, M. Buzea, M. Licker, M. Rus, A. Földes, E. SzékelySummarySeveral Romanian hospitals have noted increasing isolation of Providencia stuartii strains in recent years, with an alarming rate of carbapenem resistance. In order to provide molecular epidemiological data regarding their dissemination, 77 P. stuartii strains collected from five hospitals located in different regions of Romania were analysed. All strains harboured IncA/C plasmid, and 67 carried the blaNDM-1 gene...
Source: Journal of Hospital Infection - June 9, 2019 Category: Infectious Diseases Source Type: research

Evaluation of surgical site infection antibiotic prophylaxis among patients receiving antibiotics for active infection
Publication date: Available online 8 June 2019Source: Journal of Hospital InfectionAuthor(s): Cynthia T. Nguyen, Claire M. Reuter, Tracy Hudson, Julius Li (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 9, 2019 Category: Infectious Diseases Source Type: research

Community prevalence of carbapenemase-producing organisms in East London
ConclusionTo date, there have been no studies investigating the prevalence of CPOs in the UK community. Given the high-risk patient population served by Barts Health NHS Trust, it is reassuring that the prevalence observed here was low. However, it should be highlighted that travel to countries not previously categorized as high risk may also pose a threat. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 8, 2019 Category: Infectious Diseases Source Type: research

Residual effect of community antimicrobial exposure on risk of hospital onset healthcare associated Clostridioides difficile infection: a case-control study using national linked data
ConclusionsCommunity antimicrobial exposure is an independent risk factor for HA-CDI and should be considered as part of the risk assessment of patients developing diarrhoea in hospital. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - June 5, 2019 Category: Infectious Diseases Source Type: research

Variations In Antibiotic Use Across India – Multicentre Study Through Global Point Prevalence Survey
Publication date: Available online 3 June 2019Source: Journal of Hospital InfectionAuthor(s): Sanjeev K. Singh, Sharmila Sengupta, Remya Antony, Sanjay Bhattacharya, Chiranjay Mukhopadhyay, V. Ramasubramanian, Anita Sharma, Suneeta Sahu, .Suhas Nirkhiwale, Dr.Sweta Gupta, Anusha Rohit, Sunil Sharma, Vaidehi Raghavan, Purabi Barman, Smita Sood, Dhruv Mamtora, Sukhanya Rengaswamy, Anita Arora, Herman Goossens, Ann VersportenSummaryThe aim of the study was to assess antimicrobial prescribing patterns, and variation in practice, in India. A point prevalence survey (PPS) was conducted in Oct-Dec 2017 in 16 tertiary care hospita...
Source: Journal of Hospital Infection - June 4, 2019 Category: Infectious Diseases Source Type: research

Norovirus Recovery from Floors and Air after Different Decontamination Protocols
Publication date: Available online 2 June 2019Source: Journal of Hospital InfectionAuthor(s): Caroline L. Ciofi-Silva, Camila Q.M. Bruna, Rita D.C. Carmona, Alda G.C.D. Almeida, Fabiana C.P. dos Santos, Natalia M. Inada, Vanderlei S. Bagnato, Kazuko U. GrazianoSummaryBackgroundThe dispersal of airborne norovirus (NoV) particles from the floor after faecal or vomit contamination is a challenge for infection control, as this pathogen is infectious at low doses. Therefore, it is imperative to establish a safe protocol for floor decontamination.AimTo assess the presence of residual NoV-GII particles on floor and airborne parti...
Source: Journal of Hospital Infection - June 3, 2019 Category: Infectious Diseases Source Type: research

Letter to the Editor
Publication date: Available online 29 May 2019Source: Journal of Hospital InfectionAuthor(s): Bente Olesen, Inge Ulriksen, Mikkel Kreiner-Moeller, Dorthe Tomsen, Anne-Marie Thye (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - May 31, 2019 Category: Infectious Diseases Source Type: research

Working Party Guidance on the control of multi-resistant Acinetobacter outbreaks
Publication date: Available online 29 May 2019Source: Journal of Hospital InfectionAuthor(s): Barry Cookson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - May 29, 2019 Category: Infectious Diseases Source Type: research

Continuous Monitoring of Aerial Bioburden within Intensive Care Isolation Rooms and Identification of ‘High Risk’ Activities
ConclusionPeaks in airborne contamination showed a direct relation to an increase in activity levels. This study provides first clear evidence of the extent of variability in microbial airborne levels over 24-hour periods in ICU isolation rooms and directly correlates microbial load to ward activity. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - May 29, 2019 Category: Infectious Diseases Source Type: research

Mitigation of microbial contamination from waste water and aerosolization by sink design
ConclusionsLimiting microbial contamination is critical for the control of nosocomial infections of in-room sinks, which provide a major source of contamination. Our experimental sink studies document that regular ozonated water rinsing of the sink surface, decontamination of p-trap water, and UV decontamination of surfaces limits microbial aerosolization and surface contamination, with potential to decrease patient exposure and reduce hospital acquired infections. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - May 29, 2019 Category: Infectious Diseases Source Type: research

A survey to quantify wet loads after steam sterilisation processes in healthcare facilities
Publication date: Available online 24 May 2019Source: Journal of Hospital InfectionAuthor(s): Josephus P.C.M. van Doornmalen, Francesco Tessarolo, Nicole Lapanaitis, Krist Henrotin, Agostino Inglese, Harry Oussoren, Rafael Queiroz de SouzaSummaryWet loads after steam sterilisation of medical devices in health care facilities are unacceptable. However, little is known about their frequency in daily practice. Via four national sterilisation associations, in Australia (VIC SRACA), Belgium (VSZ), Italy (AIOS), and the Netherlands (VDSMH), an online survey was distributed. 78% of 125 hospital sterilisation facilities recognised...
Source: Journal of Hospital Infection - May 25, 2019 Category: Infectious Diseases Source Type: research

An Outbreak of MRSA colonisation in a Neonatal intensive care unit: use of a case control study to investigate and control it and lessons learned
We describe the investigation and management of an MRSA outbreak on a neonatal intensive care unit (NICU) and the lessons learnt.Study designOutbreak report and case-control study.Study setting and participants: The study was conducted in a 40-cot NICU in a tertiary referral hospital and included all infants colonised/infected with gentamicin-resistant MRSA.InterventionsStandard infection control measures including segregation of infants, barrier precautions, enhanced cleaning, assessment of staff practice including hand hygiene, and increased MRSA screening of infants were implemented. Continued MRSA acquisitions led to s...
Source: Journal of Hospital Infection - May 25, 2019 Category: Infectious Diseases Source Type: research

Escherichia coli bloodstream infection outcomes and preventability; a 6 month prospective observational study
ConclusionsE. coli BSI has an appreciable mortality, with little in the way of modifiable risk factors for mortality or prolonged hospital stay. Attention to urinary catheter use is likely to be the most useful way to reduce the incidence, but current UK reduction targets may be unachievable. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - May 23, 2019 Category: Infectious Diseases Source Type: research