Danish experience of meticillin-resistant Staphylococcus aureus eradication with emphasis on nose-throat colonization and supplementary systemic antibiotic treatment
Publication date: Available online 9 September 2019Source: Journal of Hospital InfectionAuthor(s): Ina Sleimann Petersen, Judit Marta Christensen, Anne Bak Zeuthen, Pia Bruun MadsenSummaryThe study-aim was to evaluate the Danish national Board of Health's guidance for treating MRSA carriage focusing on MRSA nose-throat carriage and use of supplementary systemic antibiotics. We analyze results of MRSA eradication treatment of 358 patients, focusing on those with nose (n=58) or throat (n=183) MRSA colonization. We found that the Danish guidance for treating MRSA have greater success for patients with nose colonization (66%) ...
Source: Journal of Hospital Infection - September 11, 2019 Category: Infectious Diseases Source Type: research

Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus
ConclusionXpert SA Nasal Complete for MRSA detection, Xpert C. difficile, and Xpert Norovirus can be used as POCT solely by HCWs in a ward setting. Each assay was used throughout a seven-day/24 h period with potential positive impact on bed management and patient care. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 9, 2019 Category: Infectious Diseases Source Type: research

Antibiotic decision making in surgical intensive care: a qualitative analysis
ConclusionsAntibiotic decision making in the SICU is a complex process involving multiple clinician teams with varying levels of physical proximity to and autonomy over patient cases. This study found that the SICU clinician team has increased physical proximity to patient cases but little autonomy over antibiotic decisions. If these characteristics are not considered, antimicrobial stewardship (AMS) interventions may have diminished success in addressing high levels of the antibiotic use in the SICU. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 8, 2019 Category: Infectious Diseases Source Type: research

Levofloxacin-resistant Stenotrophomonas maltophilia: risk factors and antibiotic susceptibility patterns in hospitalized patients
ConclusionLRSM antibiotic susceptibility patterns revealed multiple-drug resistance, which further limits treatment options for clinicians. To reduce LRSM occurrence, proper use of antibiotics, especially fluoroquinolones, is mandatory. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 8, 2019 Category: Infectious Diseases Source Type: research

Contamination of the water system with Pseudomonas aeruginosa after implementation of antiseptic bathing with a leave-on product
Publication date: Available online 4 September 2019Source: Journal of Hospital InfectionAuthor(s): Andreas Friedrich Wendel, Frauke Mattner (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

A Service Evaluation of Simultaneous near Patient Testing for Influenza, RSV, Clostridium difficle and Norovirus in a UK District General Hospital
ConclusionsLocal GXP testing compared to centralised multiplex PCR testing for IF, NV and CD, demonstrated sensitivities, specificities and NPV between 95% - 100%. Turnaround times were faster, enabling quicker infection prevention and control decision making. In our local setting (WCUH), the GXP demonstrated the potential to reduce NV and IFA/B outbreaks. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Lowbury Lecture 2018. Chlorhexidine-Based Decolonization to Reduce Healthcare-Associated Infections and Multidrug-Resistant Organisms (MDROs): Who, What, Where, When, and Why?
Publication date: Available online 5 September 2019Source: Journal of Hospital InfectionAuthor(s): Susan S. HuangSummaryBody surface decolonization with chlorhexidine bathing and nasal mupirocin has become a simple solution for prevention of healthcare-associated infections. The clinical trial evidence for this practice will be reviewed to understand who benefits from this practice, for what reasons, and at what times. The method of bathing and nasal decolonization will also be discussed as proper application is needed for maximal effectiveness. Finally, the conflict between current effectiveness and future potential for f...
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Detection of methicillin resistant Staphylococcus aureus and carbapenemase-producing enterobacteria in Danish Emergency Departments – evaluation of national screening guidelines
ConclusionThe national screening tools were of limited use since the majority of MRSA and CPE carriers will pass unidentified through the ED, and many patients will be isolated unnecessarily. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: September 2019Source: Journal of Hospital Infection, Volume 103, Issue 1Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Impact of test protocols and material binding on the efficacy of antimicrobial wipes
ConclusionsThe use of different wiping cloth materials may not impact severely on the efficacy of potent disinfectants, despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be at higher risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Service evaluation of alcohol-release door plates: an addition to hand hygiene
Publication date: September 2019Source: Journal of Hospital Infection, Volume 103, Issue 1Author(s): M.H. Wilcox, A. DycheSummaryA service evaluation was designed to examine the effect of installation of alcohol-releasing Surfaceskins doorplates on routine alcohol hand gel hygiene use by healthcare workers. There was an approximate doubling increase in healthcare worker use of alcohol hand gel dispensers following the installation of Surfaceskins doorplates in two operating theatre suites. No evidence was found that Surfaceskins doorplates replaced routine hand hygiene. It is concluded that these devices represent a useful...
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Bacterial cross-infection related to the use of bladeless fans in a clinical setting
Publication date: Available online 3 September 2019Source: Journal of Hospital InfectionAuthor(s): J. Dhanda, J. Gray, H. White (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Reducing Implant Infection in Orthopaedics (RIIiO): Results of a Pilot Study Comparing the Influence of Forced Air and Resistive Fabric Warming Technologies on Post-Operative Infections following Orthopaedic Implant Surgery
We report results of a pilot study in patients over the age of 65 undergoing hemiarthroplasty following fractured neck of femur.AimTo establish the recruitment and data management strategies needed for a full trial comparing post-operative infection rates associated with forced air versus resistive fabric warming.MethodsParticipants were randomised 1:1 in permuted blocks to forced air or resistive fabric warming. Hypothermia was defined as a temperature of
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Clinical impacts of delayed central venous catheter removal according to the severity of comorbidities in patients with candidaemia
ConclusionEarly CVC removal may improve the survival of patients with candidaemia and low CCI scores, but no such protective effect was evident in those with high CCI scores. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2019 Category: Infectious Diseases Source Type: research

Detection of norovirus in air samples in a non-vomiting patient: implications of testing saliva for norovirus in an immunocompromised host
Publication date: Available online 25 July 2019Source: Journal of Hospital InfectionAuthor(s): V.C.C. Cheng, S-C. Wong, K.H.Y. Chiu, C.C.Y. Yip, S.C.Y. Wong, K-Y. Yuen (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 30, 2019 Category: Infectious Diseases Source Type: research

In-vitro activity of active ingredients of disinfectants against drug-resistant fungi
Publication date: Available online 27 July 2019Source: Journal of Hospital InfectionAuthor(s): R. Stauf, D. Todt, E. Steinmann, P-M. Rath, H. Gabriel, J. Steinmann, F.H.H. BrillSummaryThe biocidal activities of peracetic acid and ethanol were tested against nine clinical fungal isolates and four reference strains. Ethanol was active (≥4.0 log10 reduction) against yeasts at a concentration of 50% v/v and against moulds at 80% v/v. Exposure times in both cases were 1 min. Peracetic acid was active as a 0.25% solution against yeasts and as a 0.5% solution against moulds; exposure times in both cases were 5 min. Compared wi...
Source: Journal of Hospital Infection - August 30, 2019 Category: Infectious Diseases Source Type: research

Approaches to the detection of Clostridioides difficile in the healthcare environment
Publication date: Available online 24 August 2019Source: Journal of Hospital InfectionAuthor(s): R.J. Grainger, N.T. Stevens, H. HumphreysAbstractClostridioides difficile, a spore-forming bacillus, is a major cause of healthcare-associated infection, and can survive for prolonged periods in the inanimate environment. Environmental sampling to detect C. difficile is not routine but may be undertaken as part of outbreak management and during research projects. We conducted a literature search between 1980 and 2018 to review methods for the detection of this pathogen in the environment. There are many acceptable sampling meth...
Source: Journal of Hospital Infection - August 26, 2019 Category: Infectious Diseases Source Type: research

Increased fluid intake for the prevention of urinary tract infection in adults and children in all settings: A systematic review
Publication date: Available online 23 August 2019Source: Journal of Hospital InfectionAuthor(s): Oyebola Fasugba, Brett G. Mitchell, Elizabeth McInnes, Jane Koerner, Allen C. Cheng, Heilok Cheng, Sandy MiddletonSummaryBackgroundNon-antibiotic interventions for urinary tract infection (UTI) prevention have been investigated as a strategy to reduce antibiotic prescribing for UTI and subsequent antibiotic resistance. Increased hydration is widely advocated for preventing UTI; however, evidence for its effectiveness is unknown.AimTo systematically review the published literature on the effectiveness of increased fluid intake a...
Source: Journal of Hospital Infection - August 24, 2019 Category: Infectious Diseases Source Type: research

Bundled skin antiseptic preparation for complex cardiac implantable electronic device infection – a propensity score matching cohort study
ConclusionsBundled skin antiseptic preparation is an effective and widely applicable strategy for decreasing infection risk after a complex CIED implantation. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 24, 2019 Category: Infectious Diseases Source Type: research

Enterococcus hirae, Enterococcus faecium and Enterococcus faecalis show different sensitivities to typical biocidal agents used for disinfection
ConclusionE. hirae is a suitable species when a bactericidal activity should be determined against enterococci with glutaraldehyde and peracetic acid. E. hirae may not be a suitable species for ethanol or sodium hypochlorite if the bactericidal activity should include the clinical pathogens E. faecium and E. faecalis. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 24, 2019 Category: Infectious Diseases Source Type: research

Cost analysis for electron time-flow taps and point of use filters: a comparison of two methods for Legionnaires' disease prevention in hospital water networks
Publication date: Available online 13 July 2019Source: Journal of Hospital InfectionAuthor(s): M. Totaro, E. De Vita, T. Mariotti, C. Bisordi, S. Giorgi, A. Gallo, A.L. Costa, B. Casini, P. Valentini, G. Privitera, A. Baggiani (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 21, 2019 Category: Infectious Diseases Source Type: research

Top Research Priorities in Healthcare-Associated Infections in the United Kingdom
ConclusionsA priority-setting process using JLA methods and principles involving patients, carers and healthcare professionals was used to identify top 10 priority areas for research related to HCAI. To address these uncertainties basic, translational, clinical, and public health research would be required. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 18, 2019 Category: Infectious Diseases Source Type: research

A Laboratory brucella exposure in a uk hospital: a swiss cheese model?
Publication date: Available online 16 August 2019Source: Journal of Hospital InfectionAuthor(s): Fahima Begum, Charles Tilsed, Alastair McGregor, Gopal Rao (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 18, 2019 Category: Infectious Diseases Source Type: research

VIM carbapenemase-producing Escherichia coli in a residential care home in The Netherlands
ConclusionTo successfully control the outbreak a customized bundled approach was necessary. Current guidelines should be adapted to be suitable for all types of residential care homes and to effectively combat the spread of multi resistant pathogens. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 18, 2019 Category: Infectious Diseases Source Type: research

Bayesian reconstruction of a vancomycin-resistant Enterococcus transmission route using epidemiologic data and genomic variants from whole genome sequencing
ConclusionA Bayesian approach for transmission route reconstruction using epidemiologic data and genomic variants from WGS can be applied in actual VRE outbreaks. This may contribute to the design and implementation of effective infection control measures. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 18, 2019 Category: Infectious Diseases Source Type: research

Development of consensus based international antimicrobial stewardship competencies for undergraduate nurse education
ConclusionThe competency descriptors should be used to direct undergraduate nurse education, and the AMS practices of qualified nurses (including those working in new roles such as Nursing Associates) given the high levels of agreement reached on competency descriptors. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 15, 2019 Category: Infectious Diseases Source Type: research

Contamination of sink drains with carbapenemase-producing Enterobacteriaceae in intensive care units: a concern but don’t worry so much!
Publication date: Available online 13 August 2019Source: Journal of Hospital InfectionAuthor(s): Matthieu Eveillard, Carole Lemarié, Clément Legeay, Catherine Ramont, Laura Onillon, Maxime Corre, Sigismond Lasocki (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 15, 2019 Category: Infectious Diseases Source Type: research

Exogenous acquisition of Pseudomonas aeruginosa in intensive care units: a prospective multicentre study, DYNAPYO study.
Publication date: Available online 13 August 2019Source: Journal of Hospital InfectionAuthor(s): Maïder Coppry, Camille Leroyer, Marion Saly, Anne-Gaëlle Venier, Céline Slekovec, Xavier Bertrand, Sylvie Parer, Serge Alfandari, Emmanuelle Cambau, Bruno Megarbane, Christine Lawrence, Bernard Clair, Alain Lepape, Pierre Cassier, Dominique Trivier, Alexandre Boyer, Hélène Boulestreau, Julien Asselineau, Véronique Dubois, Rodolphe ThiébautSummaryPseudomonas aeruginosa remains one of the most common nosocomial pathogens in intensive care units (ICUs). Although exogenous acquisition ha...
Source: Journal of Hospital Infection - August 14, 2019 Category: Infectious Diseases Source Type: research

Circulation of a community healthcare-associated multiply-resistant meticillin-resistant Staphylococcus aureus lineage in South Yorkshire identified by whole genome sequencing
ConclusionGenomic and epidemiological analyses indicate community-based transmission of a multiply resistant MRSA clone within South Yorkshire introduced around 2012–2013, prior to the detection of a spatial–temporal cluster associated with a distinct risk group. Surveillance data indicate continued circulation. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 11, 2019 Category: Infectious Diseases Source Type: research

Sink drain contamination with extended-spectrum-beta-lactamase-producing Enterobacteriaceae (ESBLE) in intensive care units: strong correlation to the ESBLE colonization pressure in patients but not same species
Publication date: Available online 10 August 2019Source: Journal of Hospital InfectionAuthor(s): C. Lemarié, C. Legeay, S. Lasocki, R.Mahieu, A. Kouatchet, L. Bahier, L. Onillon, M. Corre, M. Kempf, M. EveillardSummarySink drains (SD) of six intensive care units (ICUs) were sampled for screening contamination with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLE). A high prevalence (59.4%) of SD contamination was observed. Analyzing the data by ICU, the ratio “number of ESBLE species isolated in SD/total number of SD sampled” was strongly correlated (Spearman coefficient, 0.87; P = .0...
Source: Journal of Hospital Infection - August 11, 2019 Category: Infectious Diseases Source Type: research

Prion disease and recommended procedures for flexible endoscope reprocessing – review of policies worldwide and proposal for a simplified approach
Publication date: Available online 10 August 2019Source: Journal of Hospital InfectionAuthor(s): Günter Kampf, Michael Jung, Miranda Suchomel, Philippe Saliou, Helen Griffiths, Margreet C. VosSummarySeveral guidelines recommend specific treatments for endoscopes, procedures of quarantine for endoscopes or additional treatments for the endoscope washer disinfector (EWD) in suspected or confirmed cases of CJD or vCJD but vary in many details. We therefore reviewed guidelines on reprocessing flexible endoscopes after use in patients with suspected or confirmed prion disease. In addition, a literature search was done on M...
Source: Journal of Hospital Infection - August 11, 2019 Category: Infectious Diseases Source Type: research

Effect of Chlorhexidine bathing on colonization or infection with Acinetobacter baumannii-a systematic review and meta-analysis
Publication date: Available online 9 August 2019Source: Journal of Hospital InfectionAuthor(s): Cheng-Yi Fan, Wan-Ting Lee, Tzu-Chun Hsu, Cheng-Han Lee, Shiao-Pei Wang, Wen-Shan Chen, Chien-Hua Huang, Chien-Chang LeeSummaryBackgrounds: Healthcare-associated infections (HAI) caused by multidrug-resistant Gram-negative bacteria (MDRGNB) have increased prevalence in intensive care units (ICUs). A common strategy to prevent HAI is bathing patients with chlorhexidine gluconate (CHG). However, the effectiveness of CHG bathing against multidrug-resistant Acinetobacter baumannii (MDRAB) is still controversial.AimTo perform a syste...
Source: Journal of Hospital Infection - August 11, 2019 Category: Infectious Diseases Source Type: research

S. Dewar et al. Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus
ConclusionXpert SA Nasal Complete for MRSA detection, Xpert C. difficile, and Xpert Norovirus can be used as POCT solely by HCWs in a ward setting. Each assay was used throughout a seven-day/24 h period with potential positive impact on bed management and patient care. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 11, 2019 Category: Infectious Diseases Source Type: research

Difficulty in removing biofilm from dry surfaces
This report demonstrates that a Staphylococcus aureus biofilm is significantly more difficult to remove than dried planktonic bacteria. A single wiping action removed>99.9% (>3 log10) of dried planktonic bacteria, whereas only 1.4 log10 of biofilm (96.66%) was removed by 50 wiping actions with a standardized wiping process. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 9, 2019 Category: Infectious Diseases Source Type: research

Lessons learnt from influenza POCT implementation in an AMU
Publication date: Available online 6 August 2019Source: Journal of Hospital InfectionAuthor(s): Mark I. Garvey, Martin Biggs, Vinay Reddy-Kolanu, Hayley Flavell, Amy Wallett, Elisabeth Holden (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 7, 2019 Category: Infectious Diseases Source Type: research

Adaptation and implementation of the ARK (Antibiotic Review Kit) Intervention to safely and substantially reduce antibiotic use in hospitals: A feasibility study
Publication date: Available online 5 August 2019Source: Journal of Hospital InfectionAuthor(s): E.L.A. Cross, K. Sivyer, J. Islam, M. Santillo, F. Mowbray, T.E.A. Peto, A.S. Walker, L. Yardley, M.J. LlewelynStructured summaryBackgroundAntimicrobial stewardship initiatives in secondary care depend on clinicians undertaking antibiotic prescription reviews but decisions to limit antibiotic treatment at review are complex.AimTo assess the feasibility and acceptability of implementing ARK (Antibiotic Review Kit), a behaviour change intervention made up of four components (brief online tool, prescribing decision aid, regular dat...
Source: Journal of Hospital Infection - August 7, 2019 Category: Infectious Diseases Source Type: research

Barriers and opportunities experienced by staff when implementing infection prevention and control guidelines during labour and delivery in health care facilities in Nigeria
ConclusionSafe childbirth and postnatal care require comprehensive adherence to hand hygiene protocols and the use of disposable personal protective equipment. Financial, equipment, and human resource constraints are obstacles to effective implementation of IPC in labour and delivery wards in our study site. Recommended interim measures include the introduction of champions to systematise step-down trainings and to monitor and provide feedback at facility level. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 5, 2019 Category: Infectious Diseases Source Type: research

Epidemiology and impact of norovirus outbreaks in Norwegian healthcare institutions, 2005–2018
ConclusionsNorovirus outbreaks in Norwegian HCIs appears to have a substantial impact on both hospital and LTCFs all over Norway, especially during the winter months. That up to half of all cases were healthcare professionals emphasizes a need for further focus on infection control. Our results suggest that hospitals, affected first, could alert LTCFs in the area in order to prevent further outbreaks. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 4, 2019 Category: Infectious Diseases Source Type: research

Can real-time polymerase chain reaction allow a faster recovery of hospital activity in cases of an incidental discovery of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant Enterococci carriers?
ConclusionsThe use of RT-PCR (GeneXpert®) can avoid the three-weekly rectal samplings needed to rule-out acquisition of CPE/VRE. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 4, 2019 Category: Infectious Diseases Source Type: research

Novel photodynamic coatings reduce the bioburden on near-patient surface thereby reducing the risk for onward pathogen transmission – a field study in two hospitals
Publication date: Available online 29 July 2019Source: Journal of Hospital InfectionAuthor(s): A. Eichner, T. Holzmann, D. Eckl, F. Zeman, M. Koller, M. Huber, S. Pemmerl, W. Schneider-Brachert, W. BäumlerSummaryBackgroundNear-patient surfaces in hospitals are recognized as a source for healthcare-acquired infections. Such surfaces act as reservoirs for microbial contamination by which pathogens can be transmitted from colonized or infected patients to susceptible patients. Routine disinfection of surfaces results only in a temporal elimination of pathogens and recontamination inevitably occurs shortly between two con...
Source: Journal of Hospital Infection - July 30, 2019 Category: Infectious Diseases Source Type: research

How to carry out microbiological sampling of healthcare environment surfaces? A review of current evidence
ConclusionAvailable literature on sampling methods demonstrated deficits with potential improvements for future research. Many of the studies included in the review were laboratory based and not undertaken in the real hospital environment where sampling recoveries could be affected by the many variables present in a clinical environment. It was therefore difficult to draw overall conclusions, however some recommendations for the design of routine protocols for surface sampling of healthcare environments can be made. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 30, 2019 Category: Infectious Diseases Source Type: research

Local outbreak of extended spectrum beta lactamase SHV2a producing Pseudomonas aeruginosa reveals the emergence of a new specific sub-lineage of the international ST235 high risk clone
ConclusionsAmong the ST235 P. aeruginosa strains, a sub-lineage sharing a common genetic background and harbouring the blaSHV2a extended-spectrum beta-lactamase seems to emerge from different locations, yielding secondary local outbreaks. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 30, 2019 Category: Infectious Diseases Source Type: research

Molecular Epidemiology of an Outbreak of Human Parainfluenza Virus 3 Among Oncology Patients
Publication date: Available online 26 July 2019Source: Journal of Hospital InfectionAuthor(s): Emily S. Bailey, Erica Lobaugh-Jin, Becky Smith, Christopher Sova, Joey Misuraca, Nancy Henshaw, Gregory C. GrayAbstractA hospital outbreak of human parainfluenza virus type 3 in hematologic oncology patients is described in 12 patients over a 4-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggests that both community acquired and nosocomially transmitted infections occurred during this outbreak. Molecular analysis of HPIV-3 isolates indicated that a chain of transmission occurred among multiple patie...
Source: Journal of Hospital Infection - July 27, 2019 Category: Infectious Diseases Source Type: research

In vitro activity of active ingredients of disinfectants against drug-resistant fungi
Publication date: Available online 27 July 2019Source: Journal of Hospital InfectionAuthor(s): Raphael Stauf, Daniel Todt, Eike Steinmann, Peter-Michael Rath, Henrik Gabriel, Joerg Steinmann, Florian H.H. BrillSummaryThe biocidal activities of peracetic acid and ethanol were tested against nine clinical fungal isolates and four reference strains. Ethanol was active (≥ 4.0 log10-reduction) against yeasts at a concentration of 50 % v/v and against moulds at 80 % v/v. Exposure times in both cases were 1 min. Peracetic acid was active as a 0.25 % solution against yeasts and as a 0.5 % solution against moulds; exposure times...
Source: Journal of Hospital Infection - July 27, 2019 Category: Infectious Diseases Source Type: research

Detection of norovirus in air samples in patient without vomiting: implication of saliva testing for norovirus in immunocompromised host
Publication date: Available online 25 July 2019Source: Journal of Hospital InfectionAuthor(s): Vincent C.C. Cheng, Shuk-Ching Wong MNurs, Kelvin H.Y. Chiu, Cyril C.Y. Yip, Sally C.Y. Wong, Kwok-Yung Yuen (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 26, 2019 Category: Infectious Diseases Source Type: research

Evaluation of droplet production by a new design of clinical handwash basin for the healthcare environment
Publication date: Available online 3 July 2019Source: Journal of Hospital InfectionAuthor(s): S. Yui, M. Muzslay, K. Karia, B. Shuttleworth, S. Ali, N. Dudzinska, P. WilsonSummarySplashing from handwash basins may be a source of bacteria in the healthcare environment. A novel splash-reducing basin was assessed for its ability to reduce droplet formation during simulated handwashing. The basin was compared to two conventional basins commonly used in healthcare. Basins were mounted in a test system and tap flushed for 30-s with and without handwashing. Droplets were visualized with fluorescent dye. With conventional basins,&...
Source: Journal of Hospital Infection - July 26, 2019 Category: Infectious Diseases Source Type: research

Burden of Surgical Site Infections in The Netherlands: Cost analyses and Disability Adjusted Life Years
ConclusionDepending on the type of surgery, SSIs cause a significant burden; economically as well as expressed in loss of years in full health. This underlines the importance of appropriate infection prevention and control measures. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 20, 2019 Category: Infectious Diseases Source Type: research

Two-year analysis of Clostridium difficile ribotypes associated with increased severity
ConclusionsA wide range of C. difficile ribotypes were responsible for C. difficile infection presentations. Although C. difficile-associated mortality has reduced in recent years, expansion of lineages associated with increased severity could herald increases in future mortality. Enhanced surveillance for emerging lineages such as RT220 that are associated with more severe disease is required, with genomic approaches to dissect pathogenicity. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 19, 2019 Category: Infectious Diseases Source Type: research

Preventing hospital-onset Escherichia coli bacteraemia: is hydration the solution?
Publication date: Available online 28 June 2019Source: Journal of Hospital InfectionAuthor(s): R.V. Francis, T.C. Boswell, N. Mahida (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 19, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: August 2019Source: Journal of Hospital Infection, Volume 102, Issue 4Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - July 19, 2019 Category: Infectious Diseases Source Type: research