Role of antimicrobial restrictions in bacterial resistance control: a systematic literature review
ConclusionThe presumably effective restrictive strategies rely mainly on inadequately tested hypotheses and low-quality evidence. Therefore, systematic, high-quality research is needed to confirm and expand comprehension of the subject so that the most successful policies are employed in the field. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 7, 2019 Category: Infectious Diseases Source Type: research

Does improved management of asymptomatic bacteriuria in pregnant women prevent Escherichia coli bloodstream infections?
Publication date: Available online 12 October 2019Source: Journal of Hospital InfectionAuthor(s): J. Dhanda, J. Gray, E. Knox, A. Bashir (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 7, 2019 Category: Infectious Diseases Source Type: research

Alteration of antibiotic regimen as an additional control measure in suspected multi-drug-resistant Enterobacter cloacae outbreak in a neonatal intensive care unit
ConclusionsAltering the antibiotic regimen with regard to selection pressure may be considered as part of an intervention bundle to rapidly control the emergence of MDR-GNB in suspected outbreak situations in the NICU. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 5, 2019 Category: Infectious Diseases Source Type: research

Alcohol-based hand rub and influenza A: the danger of publishing a flawed study with no clinical relevance
Publication date: Available online 10 October 2019Source: Journal of Hospital InfectionAuthor(s): A. Peters, E. Frat, A. Iten, J. Sauser, M. Schibler, D. Pittet (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 5, 2019 Category: Infectious Diseases Source Type: research

Unsafe small clinics cause new human immunodeficiency virus outbreaks in Pakistan
Publication date: Available online 10 October 2019Source: Journal of Hospital InfectionAuthor(s): B.A. Khan, L. Cheng, A.A. Khan, H. Ahmed (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 5, 2019 Category: Infectious Diseases Source Type: research

Global Point Prevalence Survey (Global-PPS) of Antimicrobial Consumption in Brazilian Hospitals
ConclusionsWe observed a high prevalence of antibiotic use in the 18 Brazilian hospitals. The antibiotics were prescribed mainly empirically. Intravenous broad-spectrum antibiotics were the most frequent antimicrobials used, showing that reinforcement of de-escalation strategy is needed. The Global-PPS data can be very useful for monitoring stewardship programmes and intervention. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - November 1, 2019 Category: Infectious Diseases Source Type: research

Mobile phones as fomites for potential pathogens in hospitals: microbiome analysis reveals hidden contaminants
ConclusionThis study reinforces the need to consider infection-control policies to mitigate the potential risks associated with the increased use of smartphones in clinical environments, and highlights the limitations of culture-based methods for environmental swabbing. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 30, 2019 Category: Infectious Diseases Source Type: research

HCV and HIV epidemics among small clinics staff in Pakistan: a possible future scenario
Publication date: Available online 28 October 2019Source: Journal of Hospital InfectionAuthor(s): Aves Ahmed Khan, Bilal Ahmed Khan, Haris Ahmed (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 30, 2019 Category: Infectious Diseases Source Type: research

Genetics, epidemiology, and clinical manifestations of multidrug-resistant Acinetobacter baumannii
Publication date: Available online 4 October 2019Source: Journal of Hospital InfectionAuthor(s): P. NasrSummaryAcinetobacter baumannii infections have become an emerging health concern in hospitals across the world and are often associated with nosocomial infections with poorer clinical outcomes in patients with prolonged hospital stay. Management of infections involves prompt identification of the infecting strain, isolating the source of infection, and proper choice of antibiotic regimen. However, resistance to first-line antimicrobial drugs, combined with a lack of equally effective alternatives, complicates the treatme...
Source: Journal of Hospital Infection - October 26, 2019 Category: Infectious Diseases Source Type: research

A survey of the implementation status of selected infection control strategies in neonatal intensive care units in Japan
ConclusionInfection prevention and control practices regarding active pathogen surveillance cultures and the use of barrier precautions varied widely in Japanese neonatal units. National guidelines and evidence-based recommendations are needed to rationalize and standardize current infection prevention and control practices in neonatal units in Japan. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2019 Category: Infectious Diseases Source Type: research

Letter to the editor on ‘Primary prevention of Clostridioides difficile infection with combination probiotics’
Publication date: Available online 19 October 2019Source: Journal of Hospital InfectionAuthor(s): Takahiko Nagamine (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 21, 2019 Category: Infectious Diseases Source Type: research

A point prevalence study to determine the inpatient rate of carbapenemase-producing organisms at a large London NHS Trust
ConclusionThe overall prevalence of CPOs at Barts Health Trust was 3.1%, comprising NDM and OXA-48-type carbapenemases, which is in line with other London-based studies. Renal patients and the elderly had the highest burden of CPOs, whereas previous hospitalization and foreign travel were associated with an increased risk of CPO carriage. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Long-term endemic situation caused by a linezolid- and methicillin-resistant clone of Staphylococcus epidermidis in a tertiary hospital
ConclusionAn ST2 LZD- and methicillin-resistant clone was established in the whole hospital, not only in the ICU but also in wards where LZD consumption is low. This highlights the need to implement and maintain infection control measures as well as antimicrobial stewardship programs in all hospital units, to preserve the efficacy of LZD. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Lessons learnt from influenza POCT implementation in an acute medical unit
Publication date: November 2019Source: Journal of Hospital Infection, Volume 103, Issue 3Author(s): M.I. Garvey, M. Biggs, V. Reddy-Kolanu, H. Flavell, A. Wallett, E. Holden (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: November 2019Source: Journal of Hospital Infection, Volume 103, Issue 3Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Effect of chlorhexidine bathing on colonization or infection with Acinetobacter baumannii: a systematic review and meta-analysis
Publication date: November 2019Source: Journal of Hospital Infection, Volume 103, Issue 3Author(s): C.-Y. Fan, W.-T. Lee, T.-C. Hsu, C.-H. Lee, S.-P. Wang, W.-S. Chen, C.-H. Huang, C.-C. LeeSummaryHealthcare-associated infections (HAIs) caused by multi-drug-resistant Gram-negative bacteria (MDRGNB) have increased prevalence in intensive care units (ICUs). A common strategy to prevent HAIs is bathing patients with chlorhexidine gluconate (CHG). However, the effectiveness of CHG bathing against multidrug-resistant Acinetobacter baumannii (MDRAB) is still controversial. The aim of this study was to perform a systematic review...
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Burden of surgical site infections in the Netherlands: cost analyses and disability-adjusted life years
Publication date: November 2019Source: Journal of Hospital Infection, Volume 103, Issue 3Author(s): M.B.G. Koek, T.I.I. van der Kooi, F.C.A. Stigter, P.T. de Boer, B. de Gier, T.E.M. Hopmans, S.C. de Greeff, J. Entius, J.C.M. Diederen, E.H. Groenendijk, L. Nolles, K.P. Jalink-Olthof, B.J.H. den Broeder, H.G.M. BlaauwgeersSummaryBackgroundSurgical site infections (SSIs) are associated with morbidity, mortality and costs.AimTo identify the burden of (deep) SSIs in costs and disability-adjusted life years (DALYs) following colectomy, mastectomy and total hip arthroplasty (THA) in the Netherlands.MethodsA retrospective cost-an...
Source: Journal of Hospital Infection - October 19, 2019 Category: Infectious Diseases Source Type: research

Getting the timing right: is it worthwhile to vaccinate long-stay hospital inpatients to prevent influenza?
Publication date: Available online 11 September 2019Source: Journal of Hospital InfectionAuthor(s): E. Skelly, M. Skally, M. Foley, L. Gaughan, F. Duffy, K. Burns, H. Humphreys, F. Fitzpatrick (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 18, 2019 Category: Infectious Diseases Source Type: research

The conundrum of ultraclean air, deep infections, and artificial joint replacement
Publication date: Available online 26 September 2019Source: Journal of Hospital InfectionAuthor(s): H. Humphreys, P. Hoffman (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 18, 2019 Category: Infectious Diseases Source Type: research

The drugs don’t work: evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance
Publication date: Available online 16 October 2019Source: Journal of Hospital InfectionAuthor(s): Rabia Ahmed, Amreen Bashir, James E.P. Brown, Jonathan A.G. Cox, Anthony C. Hilton, Charlotte E. Hilton, Peter A. Lambert, Eirini Theodosiou, Jonathan Q. Tritter, Samuel J. Watkin, Tony WorthingtonSummaryIncreased public awareness of antimicrobial resistance (AMR) is a key component of effective antimicrobial stewardship strategies. Educational theatre combined with an expert panel was used to engage the public about AMR through delivery of a play entitled “The drugs don’t work”. Audience knowledge and unders...
Source: Journal of Hospital Infection - October 17, 2019 Category: Infectious Diseases Source Type: research

Reduction of turnaround time for non-tuberculous mycobacteria detection in heater-cooler units by propidium monoazide real-time PCR
Publication date: Available online 16 October 2019Source: Journal of Hospital InfectionAuthor(s): Savina Ditommaso, Monica Giacomuzzi, Gabriele Memoli, Rossana Cavallo, Antonio Curtoni, Maria Avolio, Carlo Silvestre, Carla M. ZottiSummaryBackgroundInvasive non-tuberculous mycobacteria (NTM) infections are emerging worldwide in patients undergoing open-chest cardiac bypass surgery exposed to contaminated heater-cooler units (HCUs). Although this outbreak has been investigated by culturing bacteria isolated from HCU aerosol and water samples, these conventional methods have low-analytic sensitivity, high rates of sample cont...
Source: Journal of Hospital Infection - October 17, 2019 Category: Infectious Diseases Source Type: research

Detection of meticillin-resistant Staphylococcus aureus and carbapenemase-producing Enterobacteriaceae in Danish emergency departments – evaluation of national screening guidelines
ConclusionThe national screening tools were of limited use as the majority of MRSA and CPE carriers passed unidentified through the EDs, and many patients were isolated unnecessarily. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 16, 2019 Category: Infectious Diseases Source Type: research

Trends in prevalence of healthcare-associated infections and antimicrobial use in hospitals in the Netherlands: 10 years of national point-prevalence surveys
ConclusionRepeated PPS data from 2007 to 2016 show a decrease in the prevalence of patients with HCAI with onset during hospitalization, and a stable prevalence of patients with HCAI at admission. The adjusted OR of 0.97 for HCAI during hospitalization indicates a true reduction in prevalence of approximately 3% per year. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 16, 2019 Category: Infectious Diseases Source Type: research

Antimicrobial stewardship intervention: optimizing antibiotic treatment in hospitalized patients with reported antibiotic allergy
ConclusionThis antimicrobial stewardship intervention can be used to provide patients with reported antibiotic allergy labels with the preferred antibiotic treatment and to de-label them after uneventful re-exposure to the antibiotic agent. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 15, 2019 Category: Infectious Diseases Source Type: research

Does improved management of asymptomatic bateriuria in pregnant women prevent E. coli bloodstream infections?
Publication date: Available online 12 October 2019Source: Journal of Hospital InfectionAuthor(s): Jaspreet Dhanda, James Gray, Ellen Knox, Amreen Bashir (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2019 Category: Infectious Diseases Source Type: research

Variable impact of an antimicrobial stewardship programme in three intensive care units: time-series analysis of 2012-2017 surveillance data
ConclusionIn real life conditions and with the same antimicrobial stewardship programme (AMSP) led by a single team, impact of PPRF was heterogeneous between ICUs. Factors driving impact of AMSP should be further assessed in comparable settings through real life data, to target where they could prove cost-effective. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 11, 2019 Category: Infectious Diseases Source Type: research

Unsafe small clinics practices causing new HIV outbreaks in Pakistan
Publication date: Available online 10 October 2019Source: Journal of Hospital InfectionAuthor(s): Bilal Ahmed Khan, Longsheng Cheng, Aves Ahmed Khan, Haris Ahmed (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 11, 2019 Category: Infectious Diseases Source Type: research

Handwashing sinks as the source of transmission of ST16 carbapenem-resistant Klebsiella pneumoniae, an international high-risk clone, in ICU
This study highlights sinks as an important source of multidrug-resistant organisms. Sink management including prohibition of disposal body fluid and daily disinfection with chlorine curbed the transmission. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 11, 2019 Category: Infectious Diseases Source Type: research

Alcohol-based handrub and Influenza A: the danger of publishing a flawed study with no clinical relevance
Publication date: Available online 10 October 2019Source: Journal of Hospital InfectionAuthor(s): Alexandra Peters, Ellen Frat, Anne Iten, Julien Sauser, Manuel Schibler, Didier Pittet (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 11, 2019 Category: Infectious Diseases Source Type: research

Transmission of multidrug-resistant Gram-negative bacteria from colonized mothers to their infants: a systematic review and meta-analysis
ConclusionsThis systematic review strongly supports MDR- and/or ESBL Enterobacteriaceae transmission from colonized mothers to their infants, with subsequent infant colonization. The risk factors contributing to transmission of MDR-GNB between colonized mothers and their infants warrants further research. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 9, 2019 Category: Infectious Diseases Source Type: research

Genetics, Epidemiology and Clinical Manifestations of Multidrug-Resistant Acinetobacter baumannii
Publication date: Available online 4 October 2019Source: Journal of Hospital InfectionAuthor(s): Payman NasrSummaryAcinetobacter baumannii infections have become an emerging health concern in hospitals across the world and are often associated with nosocomial infections with poorer clinical outcomes in patients with prolonged hospital stay. Management of infections involves prompt identification of the infecting strain, isolating the source of infection, and proper choice of antibiotic regimen. However, resistance to first-line antimicrobial drugs, combined with a lack of equally effective alternatives, complicates the tre...
Source: Journal of Hospital Infection - October 5, 2019 Category: Infectious Diseases Source Type: research

Top research priorities in healthcare-associated infection in the UK
ConclusionsA priority setting process using JLA methods and principles involving patients, carers and healthcare professionals was used to identify the top 10 priority areas for research related to HCAI. Basic, translational, clinical and public health research would be required to address these uncertainties. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2019 Category: Infectious Diseases Source Type: research

Contamination of sink drains with carbapenemase-producing Enterobacteriaceae in intensive care units: a concern but don't worry so much!
Publication date: Available online 9 September 2019Source: Journal of Hospital InfectionAuthor(s): A. Kearney, M.A. Boyle, H. Humphreys (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 3, 2019 Category: Infectious Diseases Source Type: research

Invasive Pulmonary Aspergillosis: Comparative Analysis in Cancer Patients with Underlying Haematologic Malignancies Versus Solid Tumors
Publication date: Available online 1 October 2019Source: Journal of Hospital InfectionAuthor(s): Rita Wilson Dib, Melissa C. Khalil, Johny Fares, Ray Y. Hachem, Ying Jiang, Anne-Marie Chaftari, Issam I. RaadSummaryBackgroundInvasive pulmonary aspergillosis (IPA) is commonly associated with haematologic malignancies but also occurs with solid tumors.AimComparing the diagnostic approaches and therapeutic outcomes for IPA between patients with haematologic malignancies and solid cancers.MethodsWe conducted a retrospective study evaluating consecutive cases of proven and probable IPA from 2004 to 2016. We included patients>...
Source: Journal of Hospital Infection - October 2, 2019 Category: Infectious Diseases Source Type: research

Mobile phones as fomites for potential pathogens in hospitals: microbiome analysis reveals hidden contaminants
ConclusionThis study reinforces the need to consider infection control policies to mitigate the potential risks associated with the increased use of smartphones in clinical environments, and highlights the limitations of culture-based methods for environmental swabbing. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 2, 2019 Category: Infectious Diseases Source Type: research

Development of consensus-based international antimicrobial stewardship competencies for undergraduate nurse education
ConclusionThe competency descriptors should be used to direct undergraduate nurse education and the antimicrobial stewardship practices of qualified nurses (including those working in new roles such as Nursing Associates) due to the high levels of agreement reached on competency descriptors. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 1, 2019 Category: Infectious Diseases Source Type: research

A service evaluation of simultaneous near-patient testing for influenza, respiratory syncytial virus, Clostridium difficile and norovirus in a UK district general hospital
ConclusionsLocal GXP testing compared to centralized multiplex PCR testing for IF, NV and CD, demonstrated sensitivities, specificities and NPV between 95% and 100%. Turnaround times were faster, enabling quicker infection prevention and control decision making. In our local setting (WCUH), the GXP demonstrated the potential to reduce NV and IFA/B outbreaks. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 1, 2019 Category: Infectious Diseases Source Type: research

Impact of an Empiric Therapy Guide on Antibiotic Prescribing in the Emergency Department
Publication date: Available online 30 September 2019Source: Journal of Hospital InfectionAuthor(s): Kayla M. Galanter, Jackie Ho (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 1, 2019 Category: Infectious Diseases Source Type: research

A survey on the implementation status of selected infection control strategies in neonatal intensive care units in Japan
ConclusionInfection prevention and control practices regarding active pathogen surveillance cultures and the use of barrier precautions varied widely in Japanese neonatal units. National guidelines and evidence-based recommendations are needed to rationalize and standardize current infection prevention and control practices in neonatal units in Japan. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 28, 2019 Category: Infectious Diseases Source Type: research

The conundrum of ultraclean air, deep infections and artificial joint replacement
Publication date: Available online 26 September 2019Source: Journal of Hospital InfectionAuthor(s): H. Humphreys, P. Hoffman (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 28, 2019 Category: Infectious Diseases Source Type: research

Infectious complications in patients receiving ticagrelor or clopidogrel before coronary artery bypass grafting
Publication date: Available online 26 September 2019Source: Journal of Hospital InfectionAuthor(s): Magnus Dalén, Fausto BiancariSummaryThe antiplatelet agent ticagrelor has recently been found to have bactericidal activity demonstrated in vitro and in a in vivo mouse model, which warrant further clinical investigations. The aim of this study was to evaluate infectious complications after coronary artery bypass grafting in patients preoperatively treated with ticagrelor or clopidogrel. In a multicenter trial, all adult patients who were preoperatively treated with ticagrelor or clopidogrel prior to isolated primary ...
Source: Journal of Hospital Infection - September 28, 2019 Category: Infectious Diseases Source Type: research

VIM-carbapenemase-producing Escherichia coli in a residential care home in The Netherlands
ConclusionA customized bundled approach was needed to control the outbreak successfully. Current guidelines should be adapted to be suitable for all types of residential care homes in order to combat the spread of multi-resistant pathogens effectively. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 26, 2019 Category: Infectious Diseases Source Type: research

Bundled skin antiseptic preparation for complex cardiac implantable electronic device infection: a propensity-score matching cohort study
ConclusionBundled skin antiseptic preparation is an effective and widely applicable strategy for decreasing infection risk after a complex CIED implantation. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 26, 2019 Category: Infectious Diseases Source Type: research

Association of malnutrition with surgical site infections following spinal surgeries: systematic review and meta-analysis
ConclusionsMalnutrition is associated with increased risk of developing SSI after spinal surgery. Further high-quality research is warranted to investigate whether improvement of preoperative nutritional status can decrease SSI rates. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 26, 2019 Category: Infectious Diseases Source Type: research

Extended-spectrum β-lactamase Enterobacteriaceae (ESBLE) in intensive care units: strong correlation with the ESBLE colonization pressure in patients but not same species
Publication date: Available online 10 August 2019Source: Journal of Hospital InfectionAuthor(s): C. Lemarié, C. Legeay, S. Lasocki, R. Mahieu, A. Kouatchet, L. Bahier, L. Onillon, M. Corre, M. Kempf, M. EveillardSummarySink drains of six intensive care units (ICUs) were sampled for screening contamination with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLE). A high prevalence (59.4%) of sink drain contamination was observed. Analysing the data by ICU, the ratio ‘number of ESBLE species isolated in sink drains/total number of sink drains sampled’ was highly correlated (Spearman coe...
Source: Journal of Hospital Infection - September 25, 2019 Category: Infectious Diseases Source Type: research

Comparing mask fit and usability of traditional and nanofibre N95 filtering facepiece respirators before and after nursing procedures
Publication date: Available online 20 September 2019Source: Journal of Hospital InfectionAuthor(s): Lorna LK. Suen, Yue Ping Guo, Suki SK. Ho, Cypher H. Au-Yeung, Simon LamBackgroundThe reliability of N95 filtering facepiece respirators (FFRs) depends on correct fitting. The perceived usability of FFR is equally important because discomfort during usage may affect compliance. Body movements during nursing procedures may also increase the risk of face seal leakage.AimTo evaluate the mask fit and usability of the best fit 3M N95 FFRs and nanofibre N95 FFR before and after nursing procedures. The physical properties of these ...
Source: Journal of Hospital Infection - September 22, 2019 Category: Infectious Diseases Source Type: research

Evaluation of a web-based tool for labelling potential hospital outbreaks: a mixed methods study
ConclusionThe interactive web application was both usable and useful for infection control practitioners. Its implementation in routine practice could help professionals to identify potential outbreaks while creating data to train automated detection algorithms. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 22, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: October 2019Source: Journal of Hospital Infection, Volume 103, Issue 2Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 22, 2019 Category: Infectious Diseases Source Type: research

Chlorhexidine-based decolonization to reduce healthcare-associated infections and multidrug-resistant organisms (MDROs): Who, What, Where, When, and Why?
Publication date: Available online 5 September 2019Source: Journal of Hospital InfectionAuthor(s): S.S. HuangSummaryBody surface decolonization with chlorhexidine bathing and nasal mupirocin has become a simple solution for prevention of healthcare-associated infections. The clinical trial evidence for this practice will be reviewed to understand who benefits from this practice, for what reasons, and at what times. The method of bathing and nasal decolonization will also be discussed as proper application is needed for maximal effectiveness. Finally, the conflict between current effectiveness and future potential for fueli...
Source: Journal of Hospital Infection - September 20, 2019 Category: Infectious Diseases Source Type: research

The Role of Antimicrobial Restrictions in Bacterial Resistance Control: A Systematic Literature Review
ConclusionThe presumably effective restrictive strategies rely mostly on inadequately tested hypotheses and low-quality evidence. Therefore, systematic, high-quality research is needed to confirm and expand our comprehension of the subject so that the most successful policies are actually employed on the field. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 20, 2019 Category: Infectious Diseases Source Type: research