Survey of screening methods, rates and policies for the detection of carbapenemase-producing Enterobacteriaceae in English hospitals
Publication date: Available online 7 August 2018Source: Journal of Hospital InfectionAuthor(s): C. Berry, K. Davies, N. Woodford, M. Wilcox, C. ChiltonSummaryMulti-drug-resistant Gram-negative bacteria are of major clinical concern. The increasing prevalence of carbapenemase-producing Enterobacteriaceae (CPE), resistant to all beta-lactams including carbapenems and able to colonize the large intestine, represents a key threat. Rapid, accurate detection of intestinal CPE colonization is critical to minimize transmission, and hence reduce costly, difficult-to-treat CPE infections. There is currently no ‘gold standard&r...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The socio-economic impact of multidrug-resistant nosocomial infections: a qualitative study
Publication date: Available online 29 August 2018Source: Journal of Hospital InfectionAuthor(s): Y. Mo, I. Low, S.K. Tambyah, P.A. TambyahSummaryThe burden of healthcare-associated infections (HCAIs) has traditionally been measured using clinical and economic outcomes. We conducted semi-structured interviews with 18 patients or their caregivers affected by HCAI caused by multidrug-resistant organisms to better understand the human impact of HCAI. Most patients had misconceptions about HCAI and antimicrobial resistance, leading to strong negative feelings towards HCAIs despite positive views of their healthcare providers. C...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Novel colour additive for bleach disinfectant wipes reduces corrosive damage on stainless steel
Publication date: Available online 24 September 2018Source: Journal of Hospital InfectionAuthor(s): Kevin Tyan, Katherine Jin, Jason KangSummaryBleach disinfectant wipes are corrosive to hospital surfaces and equipment. We measured the effect of two widely used bleach wipes, with and without Highlight® colour additive, on stainless steel to both quantify corrosion rate and determine the effect of Highlight® on reducing surface damage caused by bleach wipes. The two bleach wipes alone caused severe corrosion (>5 mpy) while the addition of Highlight® both significantly reduced corrosion rate (
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Timing, diagnosis and treatment of surgical site infections after colonic surgery – Prospective surveillance of 1263 patients
ConclusionOrgan space infections occurred early in the postoperative course, while incisional infections were mostly detected post-discharge over the entire 30-day observation period, emphasizing the importance of proper follow-up using a systematic, complete and independent surveillance program. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Antifungal Activity of Octenidine Dihydrochloride and Ultraviolet-C light against Multidrug-Resistant Candida auris
Publication date: Available online 25 September 2018Source: Journal of Hospital InfectionAuthor(s): Pretty Ponnachan, Vivek Vinod, Unnimaya Pullanhi, Parvathy Varma, Sanjeev Singh, Raja Biswas, Anil KumarAbstractOutbreaks due to multidrug-resistant Candida auris have emerged as a large threat to modern medicine. Since skin colonization and environmental contamination have been identified as a precursor for outbreaks, we evaluated the antifungal activity of ultraviolet-C light using mercury vapor lamp with a peak emission of 254±2 nm and octenidine dihydrochloride against C. auris clinical isolates. Octenidine dihydr...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The role of the environment in the spread of healthcare associated infections
Publication date: Available online 26 September 2018Source: Journal of Hospital InfectionAuthor(s): A.P.R. Wilson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

A qualitative study of the factors impacting Antimicrobial Stewardship program delivery in regional and remote hospitals
ConclusionAMS program delivery in regional hospitals is influenced by factors that are not present in major-city hospitals. These findings provide a strong basis for the development of specific strategies to support regional hospitals to implement sustainable AMS programs. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Impact of test protocols and material binding on antimicrobial wipes efficacy
ConclusionsThe use of different wiping cloth materials might not impact severely on the efficacy of potent disinfectants despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be more at risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Why volume matters - Implications of applied volume of alcohol-based disinfectants for infection prevention
Publication date: Available online 28 September 2018Source: Journal of Hospital InfectionAuthor(s): Katrin Steinhauer, Hans-Joachim Rödger, Karin Teckemeyer, Bärbel Christiansen, Jürgen Gebel, Heike Martiny, Bernhard Meyer, Christiane Ostermeyer, Lutz Vossebein (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Implementation of infection control bundles in intensive care units: which parameters are applicable in low-to-middle income countries?
Publication date: Available online 29 September 2018Source: Journal of Hospital InfectionAuthor(s): E. Alp, J. Rello (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Strategies to improve hand hygiene compliance among healthcare workers in adult intensive care units: a mini systematic review
ConclusionAvailable data suggest that multi-modal interventions are effective in raising the compliance to a ‘plateau’ level but not up to the desired standard. Methodologically appropriate trials of combined interventions could enhance the evidence about interventions to improve hand hygiene compliance among ICU staff. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The handwash station: friend or fiend?
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): M.J. WeinbrenSummaryHandwashing is a key barrier to cross-infection performed at a handwash station (HWS, an interface between water and drainage systems). Widespread and often uncritical placement/design and use of HWSs is not without attendant risks. Recognition of the associated hazards went unheeded for over 45 years despite warnings in the literature, until the neonatal outbreak of pseudomonas in Belfast in 2012 forced change. Minimizing risk requires a holistic approach beyond the mere testing of water from the outlet o...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Sustained improvement in hand hygiene compliance using a multi-modal improvement programme at a Swiss multi-site regional hospital
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): A. Staines, P. Vanderavero, B. Duvillard, P. Deriaz, P. Erard, F. Kundig, C. Juillet, O. ClercSummaryBackgroundEvidence of sustained improvement in hand hygiene compliance at the institutional level is scarce.AimTo assess the impact and sustainability of a hospital-wide improvement programme on hand hygiene compliance of staff.MethodsAnalysis of trends of hand hygiene compliance for all clinical staff, measured through direct observation by trained observers, within a 450-bed multi-centre teaching hospital in the county of Ne...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Feasibility of a real-time hand hygiene notification machine learning system in outpatient clinics
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): R. Geilleit, Z.Q. Hen, C.Y. Chong, A.P. Loh, N.L. Pang, G.M. Peterson, K.C. Ng, A. Huis, D.F. de KorneSummaryBackgroundVarious technologies have been developed to improve hand hygiene (HH) compliance in inpatient settings; however, little is known about the feasibility of machine learning technology for this purpose in outpatient clinics.AimTo assess the effectiveness, user experiences, and costs of implementing a real-time HH notification machine learning system in outpatient clinics.MethodsIn our mixed methods study, a mult...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Effect of an exfoliating skincare regimen on the numbers of epithelial squames on the skin of operating theatre staff, studied by surface microscopy
ConclusionsFurther work is required to demonstrate how this effect correlates with dispersion of skin particles in a cleanroom, and subsequently in live operating theatre studies. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Evaluation of ozonated water using ASTM E1174 for standardized testing of handwash formulations for healthcare personnel
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): K. Nakamura, K. Saito, J. Kashiwazaki, T. Aoyagi, K. Arai, Y. Hara, S. Kobari, H. Mori, K. Ohashi, Y. Takano, M. Kaku, K. KanemitsuSummaryRemoval of bacteria by handwashing with ozonated water was evaluated using the ASTM E1174 standard test method. Thirty healthy volunteers were assigned randomly to three groups: ozonated water, antimicrobial soap and water, and non-antimicrobial soap and water. A 3 log10 cfu reduction was achieved by washing hands with ozonated water or antimicrobial soap and water. However, ozonated w...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Obstetric competence and compliance with surgical hand antisepsis prior to elective and emergency surgical procedures: a closed-loop audit
Publication date: October 2018Source: Journal of Hospital Infection, Volume 100, Issue 2Author(s): R. Ooi, A. Griffiths (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The last days of smallpox: tragedy in Birmingham, M. Pallen. Independently published (2018), 337 pp. £11.99
Publication date: Available online 2 October 2018Source: Journal of Hospital InfectionAuthor(s): A.M. Walker (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The validity of adenosine triphosphate measurement in detecting endoscope contamination
Publication date: Available online 6 August 2018Source: Journal of Hospital InfectionAuthor(s): C.E. McCafferty, D. Abi-Hanna, M.J. Aghajani, G.T. Micali, I. Lockart, K. Vickery, I.B. Gosbell, S.O. JensenSummaryBackgroundEndoscopic procedures are vital to gastrointestinal disease diagnosis and management, but risk infection transmission. In Australia, endoscopes undergo monthly-to-quarterly microbiological testing, to prevent patient infection. Endoscopes are used more frequently, meaning contamination may not be detected by this surveillance before infection transmission occurs.AimTo evaluate the use of adenosine triphosp...
Source: Journal of Hospital Infection - September 22, 2018 Category: Infectious Diseases Source Type: research

Vagino-rectal colonisation and maternal-neonatal transmission of Enterobacteriaceae producing extended-spectrum beta-lactamases or carbapenemases: a cross-sectional study
Publication date: Available online 22 September 2018Source: Journal of Hospital InfectionAuthor(s): Carlos Jiménez-Rámila, Lorena López-Cerero, Ma Valle Aguilar Martín, Consuelo Vera Martín, Lara Serrano, Álvaro Pascual, Jesús Rodríguez-Baño.AbstractWe studied the prevalence and risk factors for colonization with ESBL-and carbapenemase-producing Enterobacteriaceae (ESBL-E, CPE) in 815 mothers and 800 newborns using a cross-sectional design; 59 women and 13 neonates were colonized by ESBL-E (prevalence [95% confidence interval], 6.7% [5.2-8.7] and 1.6 [0.7-2.5],...
Source: Journal of Hospital Infection - September 22, 2018 Category: Infectious Diseases Source Type: research

A survey on current knowledge, practice and beliefs related to preoperative antimicrobial decolonization regimens for prevention of surgical site infections among Austrian surgeons
ConclusionPreoperative decolonization seems to be performed in Austrian hospitals on a routine basis. However, this measure is implemented using a variety of modalities, antimicrobial compounds, and staff. Since our survey also demonstrated that those who are better informed about preoperative decolonization are also those who are more convinced of the usefulness of the preventive measure, future activities should not only focus on generating more comparable studies in this field, but should also include targeted education. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 21, 2018 Category: Infectious Diseases Source Type: research

Reply to Abbas et al-a response to “Infection prevention: Is copper the new gold?”
Publication date: Available online 20 September 2018Source: Journal of Hospital InfectionAuthor(s): J. Butler (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 21, 2018 Category: Infectious Diseases Source Type: research

Trends in mortality following Clostridium difficile infection in Scotland, 2010–2016: a retrospective cohort and case–control study
Publication date: Available online 25 July 2018Source: Journal of Hospital InfectionAuthor(s): A. Banks, E.K. Moore, J. Bishop, J.E. Coia, D. Brown, H. Mather, C. WiuffSummaryBackgroundNational surveillance of Clostridium difficile infection (CDI) in Scotland enables the monitoring of trends in incidence rates but not mortality.AimTo assess factors associated with mortality for all CDI cases aged ≥15 years in Scotland between 2010 and 2016.MethodsAll CDI cases aged ≥15 years in Scotland between 2010 and 2016 were linked to hospital admission and mortality datasets. Logistic regression was used to assess factors assoc...
Source: Journal of Hospital Infection - September 19, 2018 Category: Infectious Diseases Source Type: research

Clostridium difficile-related hospitalizations and risk factors for in-hospital mortality in Spain between 2001 and 2015
ConclusionCDI-related hospitalization rates are increasing, with a high burden in costs, although IHM decreased in recent years. Factors associated with IHM should be considered in the strategies for the prevention and management of CDI. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 19, 2018 Category: Infectious Diseases Source Type: research

Introduction to the joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) faecal microbiota transplant guidelines
Publication date: Available online 18 September 2018Source: Journal of Hospital InfectionAuthor(s): Benjamin H. Mullish, Mohammed Nabil Quraishi, Jonathan P. Segal, Horace R.T. Williams, Simon D. Goldenberg (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 19, 2018 Category: Infectious Diseases Source Type: research

Whole genome sequencing reveals a prolonged and spatially spread nosocomial outbreak of PVL positive MRSA (USA300)
ConclusionWGS helped to reveal an outbreak that otherwise might have stayed undetected. Nonetheless, epidemiological investigation is needed to trace the nosocomial transmission. The role of personal communication in infection control cannot be underemphasised. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 19, 2018 Category: Infectious Diseases Source Type: research

Post-exposure prophylaxis for Middle East respiratory syndrome in Healthcare workers
Publication date: Available online 18 September 2018Source: Journal of Hospital InfectionAuthor(s): So Yeon Park, Jin Seo Lee, Jun Seong Son, Jae-Hoon Ko, Kyong Ran Peck, Younghee Jung, Heung Jeong Woo, Young Soo Joo, Joong Sik Eom, Hyejin ShiSummaryAn effective post-exposure prophylaxis (PEP) strategy may limit the spread of infection. However, there is no consensus regarding PEP for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. We assessed the efficacy of ribavirin and lopinavir/ritonavir as PEP for healthcare workers (HCWs) exposed to patients with severe MERS-CoV pre-isolation pneumonia. We assesse...
Source: Journal of Hospital Infection - September 19, 2018 Category: Infectious Diseases Source Type: research

Ten intriguing article titles from the pages of the Journal of Hospital Infection
Publication date: Available online 3 August 2018Source: Journal of Hospital InfectionAuthor(s): J. Gray (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

Reply to ‘Searching for the best agent for antibiotic prophylaxis in patients undergoing transcatheter aortic valve implantation’
Publication date: Available online 29 August 2018Source: Journal of Hospital InfectionAuthor(s): M. Gallouche, P. Pavese, I. Pierre, M.R. Mallaret, J.P. Stahl, C. Landelle (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

Impact of hand sanitizer format (gel/foam/liquid) and dose amount on its sensory properties and acceptability for improving hand hygiene compliance
ConclusionThe 1.5 mL dose yielded the most acceptable properties with no extreme negative consequences. The foam provided the benefits of both the liquid and gel and combined them into a more widely acceptable format that may lead to greater hand hygiene compliance. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

Differences in Molecular Epidemiology of Staphylococcus aureus and Escherichia coli in Nursing Home Residents and People in Unassisted Living Situations
ConclusionThe molecular diversity of bacteria found within different forms of accommodation was within the same range. Hospital quality hygiene might have contributed to the absence of homogenization of the molecular diversity within the nursing home group. Diabetes mellitus might have played a role in a patient selection characterized by advanced age. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

The value of a hospital-wide point prevalence survey of carbapenemase-producing Enterobacterales; low level prevalence confirmed
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): J. Cafferkey, M. Skally, C. Finn, S. Donlon, M. Fitzpatrick, K. Burns, K. O’Connell, F. Fitzpatrick, E. Smyth, H. Humphreys (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

First Antibiotic Awareness Week Nationwide Initiative in Lebanon: Knowledge, Attitude and Practice towards Antibiotics
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): Sarah Al Omari, Hiba Al Mir, Sara Wrayde, Sabah Merhabi, Ibaa Dhaybi, Sabah Jamal, Mira Chahine, Reem Bayaa, Fatima Tourba, Houda Tantawi, Ahmad Al Atrouni, Khaled El Omari, Omar Ayash, Nina Saadallah Zeidan, Hassan Mallat, Fouad Dabboussi, Monzer Hamze, Marwan Osman, Sarah Al Omari, Hiba Al MirAbstractAntibiotic resistance is a major global health threat increasing treatment failures and medical costs. One of the most common causes contributing to the spread of ABR is self-medication. The public, as well as workers in clini...
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

Hand Hygiene in hospitals: Anatomy of a revolution
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): Thibaud Vermeil, Alexandra Peters, Claire Kilpatick, Daniela Pires, Benedetta Allegranzi, Didier PittetAbstractHealthcare-associated infections (HAI) affect hundreds of millions of individuals worldwide. Performing hand hygiene is widely accepted as a key strategy of infection prevention and control (IPC) to prevent HAI, as healthcare workers’ contaminated hands are the vehicle most often implicated in the cross-transmission of pathogens in healthcare. In the last 20 years, a paradigm shift has occurred in hand hygiene...
Source: Journal of Hospital Infection - September 18, 2018 Category: Infectious Diseases Source Type: research

Successful termination of sustained transmission of resident MRSA following extensive NICU refurbishment: an intervention study
ConclusionWe report successful termination of sustained transmission of endemic strains of MRSA from our neonatal unit following complete unit redesign and refurbishment. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 14, 2018 Category: Infectious Diseases Source Type: research

Prevalence of healthcare-associated infections in Dutch nursing homes: follow-up 2010–2017
Publication date: Available online 25 August 2018Source: Journal of Hospital InfectionAuthor(s): A. Eikelenboom-Boskamp, K. Saris, M. van Loosbroek, M.I.J. Drabbe, F. de Jongh, J.W.D. de Jong, P.G.M. Boom-Poels, A. VossSummaryFollowing the first point-prevalence study in Dutch nursing homes conducted each November from 2007 to 2009, we conducted a follow-up point-prevalence study of healthcare-associated infections (HCAIs) each November from 2010 to 2017. Similar methods and criteria were used. Resident characteristics were recorded, data collection was performed by the attending elderly care physicians via an online surve...
Source: Journal of Hospital Infection - September 12, 2018 Category: Infectious Diseases Source Type: research

An outbreak of multidrug-resistant Pseudomonas aeruginosa in a burns service in the North of England: challenges of infection prevention and control in a complex setting
ConclusionPreventing infection transmission in specialist burns services is highly challenging, and it may not always be possible to identify and eradicate the reservoirs of infection for P. aeruginosa outbreaks. Our study supports the literature, providing additional evidence that inanimate, common contact surfaces play an important role in nosocomial transmission of P. aeruginosa. These surfaces should either be decontaminated efficiently between patient contacts or be single patient use. Enhanced vigilance is crucial, and, with strict adherence to infection prevention and control procedures, it is possible to ...
Source: Journal of Hospital Infection - September 12, 2018 Category: Infectious Diseases Source Type: research

Make economics your friend
Publication date: Available online 11 September 2018Source: Journal of Hospital InfectionAuthor(s): N. GravesSummaryIn this essay I define the discipline of economics and say why it's useful. I review methods for measuring economic outcomes relevant to those working to prevent infections, and review how decision-makers should use the information to help choose the best among competing programmes. I finish by arguing that good economics can improve the amount of health gained from an infection prevention service working under conditions of scarce resources. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 12, 2018 Category: Infectious Diseases Source Type: research

Challenging biocide tolerance with antiseptic stewardship
Publication date: Available online 11 September 2018Source: Journal of Hospital InfectionAuthor(s): G. Kampf (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 12, 2018 Category: Infectious Diseases Source Type: research

Environmental contamination by bacteria in hospital washrooms according to hand-drying method: a multi-centre study
Publication date: Available online 10 July 2018Source: Journal of Hospital InfectionAuthor(s): E. Best, P. Parnell, J. Couturier, F. Barbut, A. Le Bozec, L. Arnoldo, A. Madia, S. Brusaferro, M.H. WilcoxSummaryBackgroundHand hygiene is a fundamental component of infection prevention, but few studies have examined whether hand-drying method affects the risk of dissemination of potential pathogens.AimTo perform a multi-centre, internal-crossover study comparing bacterial contamination levels in washrooms with hand-drying by either paper towels (PT) or jet air dryer (JAD; Dyson).MethodsA total of 120 sampling sessions occurred...
Source: Journal of Hospital Infection - September 7, 2018 Category: Infectious Diseases Source Type: research

Hospital Surface Contamination with antimicrobial-resistant gram-negative organisms in Tanzanian regional and tertiary hospitals: The need to improve environmental cleaning
Publication date: Available online 7 September 2018Source: Journal of Hospital InfectionAuthor(s): Nyambura Moremi, Heike Claus, Vitus Silago, Pardon Kabage, Reuben Abednego, Mecky Matee, Ulrich Vogel, Stephen E. Mshana (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 7, 2018 Category: Infectious Diseases Source Type: research

Desiccation tolerance is associated with Staphylococcus aureus hypertransmissibility, resistance and infection development in the operating room
ConclusionsIncreased desiccation tolerance is associated with intraoperative transmission of S. aureus ST 5 isolates that are linked to postoperative infection. Future work should determine whether attenuation of desiccation-tolerant, intraoperative ST 5 strains can impact the incidence of healthcare-associated infections. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 6, 2018 Category: Infectious Diseases Source Type: research

Bacterial Colonisation of Bladeless Electrical Fans
Publication date: Available online 5 September 2018Source: Journal of Hospital InfectionAuthor(s): Layth Alsaffar, Lindsey Osbourne, Nathan Thomas Bourne (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 6, 2018 Category: Infectious Diseases Source Type: research

Does simultaneous bilateral total joint arthroplasty increase deep infection risk compared to staged surgeries? A Meta-Analysis
ConclusionSBTJA does not increase the risk of subsequent PJI compared to StBTJA. Further studies are needed to provide higher quality evidence to evaluate the 2 modes of procedures. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 5, 2018 Category: Infectious Diseases Source Type: research

The local hospital milieu and healthcare-associated vancomycin-resistant enterococcus acquisition
ConclusionVRE colonization pressure was the most important risk factor for healthcare-associated VRE acquisition, regardless of VRE importation pressure. Interventions seeking to reduce VRE acquisition should focus on minimizing transmission between patients with known VRE and the local hospital environment. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 2, 2018 Category: Infectious Diseases Source Type: research

Efficacy of Antibiotic Prophylaxis against ventilator-associated pneumonia
Publication date: Available online 1 September 2018Source: Journal of Hospital InfectionAuthor(s): Nasrinsadat Mirtalaei, Aliasghar Farazi, Mohsen Ebrahimi Monfared, Abolfazl JokarAbstractVentilator-associated pneumonia (VAP) is one of the most important problems of intensive care units. 84 neurologic patients with acute stroke (Glasgow Coma Score ≤ 8) were entered into a double-blind clinical trial. Patients in the intervention group received piperacillin-tazobactam 4g/0.5g at the time of intubation and 12 hours later. The incidences of early-onset (within 4 days of intubation) and late-onset VAP were 9.2 and 26.9 epis...
Source: Journal of Hospital Infection - September 2, 2018 Category: Infectious Diseases Source Type: research

Fast update of undetected Mycobacterium chimaera infections to reveal unsuspected cases
Publication date: Available online 1 September 2018Source: Journal of Hospital InfectionAuthor(s): Fermín Acosta, Laura Pérez-Lago, María Jesús Ruiz Serrano, Mercedes Marín, Thomas A. Kohl, Nuria Lozano, Stefan Niemann, Maricela Valerio, María Olmedo, María Jesús Pérez-Granda, María Rosario Pérez Pérez, Emilio Bouza, Patricia Muñoz, Darío García de ViedmaSummaryMycobacterium chimaera is involved in a worldwide-alert owing to contaminated heater–cooler-units. We implemented an RT-PCR–based procedure to survey...
Source: Journal of Hospital Infection - September 2, 2018 Category: Infectious Diseases Source Type: research

Interventions to decrease short-term peripheral venous catheter-related bloodstream infections: impact on incidence and mortality
ConclusionsSurveillance, implementation of a multi-modal strategy and periodical assessment of healthcare workers' adherence to hospital guidelines led to a sustained reduction in PVCR-BSIs. This reduction had a major impact on S. aureus BSI rates and associated mortality. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 31, 2018 Category: Infectious Diseases Source Type: research

Season, weather and predictors of healthcare-associated Gram-negative bloodstream infections: a case-only study
ConclusionWarm seasons and daily temperature impact on the aetiology of GNB-BSI, even in models adjusted for usual risk factors. One possible explanation for these findings is that seasonality of healthcare-associated pathogens is intrinsic to micro-organisms, and not associated with comorbidities, procedures or use of antimicrobials. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - August 31, 2018 Category: Infectious Diseases Source Type: research