The impact of infections on the onset of contrast-associated acute kidney injury in patients with cirrhosis
All authors declare no conflict of interest regarding this project (Table 1b). (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 3, 2024 Category: Gastroenterology Authors: Tammo L. Tergast, Benjamin Maasoumy Tags: Letter to the Editor Source Type: research

Predicting risk of chronic liver disease in Chinese adults: external validation of the CLivD score
Chronic liver disease (CLD), including cirrhosis and liver cancer, accounts for 9.5 million deaths globally in 2017, one third of which occurred in China.1 Non-alcoholic fatty liver disease (NAFLD) alongside its metabolic risk factors has become a major risk factor for CLD.2 Based on easily accessible risk factors, the CLivD score, a simple model to predict future risk of CLD, has been developed and validated in European populations.3 This model can be used to identify individuals at high risk who could benefit from lifestyle interventions and should be referred for further liver assessment. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 3, 2024 Category: Gastroenterology Authors: Yuanjie Pang, Fredrik Åberg, Zhengming Chen, Liming Li, Christiana Kartsonaki, the China Kadoorie Biobank Collaborative Group Tags: Letter to the Editor Source Type: research

Evaluation and comparison of risk-based and universal HCV screening programs
Conceptualization, AT; CLC; Methodology, AT; Data curation, AT; Formal analysis, AT; Software, AT; Validation, AT; CLC; Writing-original draft, AT; Writing-review&editing, AT; CLC; Supervision, CLC. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 3, 2024 Category: Gastroenterology Authors: L. Alexa Thompson, Carmen L. Charlton Tags: Letter to the Editor Source Type: research

Acknowledging our reviewers
Good and timely peer review is absolutely essential for the success of the Journal of Hepatology. We are therefore extremely grateful for the support of so many colleagues who have dedicated their time this year. These reviewers have evaluated the research that was submitted to the journal and shared their insights about the papers strengths and weaknesses. This has both enabled us to make the right editorial decisions and helped our authors to further improve their work. Out of necessity, the role of the reviewer is anonymous and therefore, may go unnoticed at times. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Tags: Acknowledgement Source Type: research

Unusual early post-transplant hepatic dysfunction
A 61-year-old woman underwent liver transplantation from a brain-dead donor in February 2023 due to decompensated alcohol-related cirrhosis. The surgery was performed using the piggy-back technique with standard anastomoses, during which she required noradrenaline perfusion for haemodynamic instability, which was discontinued within the first 24 hours. The cold ischaemia time was 7.25 hours, and the warm ischaemia time was 53 minutes. The transaminase peak occurred on post-transplant Day 1 (alanine aminotransferase 832 IU/ml, aspartate aminotransferase 637 IU/ml, bilirubin 1.08 mg/dl, gamma glutamyltransferase 75 IU/ml, al...
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Authors: Fernando D íaz-Fontenla, Aránzazu Caballero-Marcos, Isabel Peligros, Jose Luis Vicario Moreno, Magdalena Salcedo Tags: What Is Your Diagnosis? Source Type: research

Editorial Board
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

Looking for exciting research to be presented at EASL Congress 2024! Submit your abstract by 16 January.
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

Register with early fees for the EASL Liver Cancer Summit!
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

Let ’s unite Hepatology! Become an EASL member today and discover your benefits
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

Get ready for the EASL Studio season 6!
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

Contents
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

JHEP at a glance (January 2024)
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Source Type: research

From the Editor ’s Desk...
In this study, Campion and coworkers aimed to evaluate the incidence and the predisposing factors of acute kidney injury (AKI) in patients with cirrhosis undergoing contrast-enhanced CT (CECT). The authors found that the incidence of AKI was not significantly increased in patients with cirrhosis undergoing CECT. Moreover, the presence of concomitant infections was the only independent predictive factor of ICM-related AKI. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 1, 2024 Category: Gastroenterology Authors: Patrizia Burra, Frank Tacke, Vlad Ratziu, Stefan Zeuzem, Bruno Sangro, Paolo Angeli Tags: From the Editor's Desk Source Type: research

IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction
The liver is one of the organs most commonly affected by metastasis. The presence of liver metastasis is reported to be responsible for an immunosuppressive microenvironment and diminished immunotherapy efficacy. Here, we aimed to investigate the role of IL-10 in liver metastasis formation and decipher its therapeutic potential in affecting immunotherapy effectiveness. (Source: Journal of Hepatology)
Source: Journal of Hepatology - December 29, 2023 Category: Gastroenterology Authors: Ahmad Mustafa Shiri, Tao Zhang, Tanja Bedke, Dimitra E. Zazara, Lilan Zhao, J öran Lücke, Morsal Sabihi, Antonella Fazio, Siwen Zhang, Daniele V.F. Tauriello, Eduard Batlle, Babett Steglich, Jan Kempski, Theodora Agalioti, Mikołaj Nawrocki, Yang Xu, Kr Tags: Research Article Source Type: research

Reply to: “Incorporating AFP-L3 and DCP in selecting patients with hepatocellular carcinoma for liver transplantation: What are the optimal criteria?”
We thank Sha et  al.1 for their insightful letter on our study,2 wherein we demonstrated that Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) and des-carboxy prothrombin (DCP) were strong predictors of post-transplant hepatocellular carcinoma (HCC) recurrence. (Source: Journal of Hepatology)
Source: Journal of Hepatology - December 26, 2023 Category: Gastroenterology Authors: Joshua S. Norman, Neil Mehta Tags: Letter to the Editor Source Type: research