Reply to “The impact of infections on the onset of contrast-associated acute kidney injury in patients with cirrhosis”
None. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 31, 2024 Category: Gastroenterology Authors: Daniela Campion, Gian Paolo Caviglia, Carlo Alessandria Tags: Letter to the Editor Source Type: research

An in-depth exploration of new clinical and prognostic characteristics of decompensated liver cirrhosis patterns
I would like to share my ideas on the publication “A new clinical and prognostic characterization of the patterns of decompensation of cirrhosis.” Marta Tonon et al. recruited a total of 617 outpatients with cirrhosis from two Italian tertiary centers (Padua and Milan) from January 2003 to June 2021 and followed prospectively until the end of t he study, death or liver transplantation.1 It is the first investigation into the role of non-acute decompensation (NAD) in patients with liver cirrhosis, which is both timely and of great significance. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 31, 2024 Category: Gastroenterology Authors: Zhongxing Ning Tags: Letter to the Editor Source Type: research

Reply to: “ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort”
We thank Dr. Krawczyk and his colleagues for the interest in our work and for the efforts to validate the role of AT-rich interaction domain 3A (ARID3A) in primary biliary cholangitis (PBC) using a large Central European cohort.1 (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 30, 2024 Category: Gastroenterology Authors: Ruqi Tang, You Li, Ruiling Chen, Xiong Ma Tags: Letter to the Editor Source Type: research

Genetic cholestasis in children and adults
Bile is produced in hepatocytes and flows to the duodenum. Cholestasis can ensue when there is either a reduction in bile flow or obstruction at any level. Proteins, including nuclear receptors, hepatobiliary transporters and structural proteins, are vital for the transport of biliary constituents and maintenance of the stability of the canalicular membrane and tight  junctions. Variants in genes encoding these proteins have been implicated in the pathogenesis of cholestasis, predominantly intrahepatic cholestasis with retention of bile acids within the liver. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 30, 2024 Category: Gastroenterology Authors: Jeremy S. Nayagam, Rosa Miquel, Richard J. Thompson, Deepak Joshi Tags: Hepatology Snapshot Source Type: research

Reply to “ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort”
We thank Dr. Krawczyk and his colleagues for the interest in our work and for the efforts to validate the role of (AT-Rich Interaction Domain 3A) ARID3A in primary biliary cholangitis (PBC) using a large Central European cohort1. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 30, 2024 Category: Gastroenterology Authors: Ruqi Tang, You Li, Ruiling Chen, Xiong Ma Tags: Letter to the Editor Source Type: research

JHEP at a glance (February 2024)
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 26, 2024 Category: Gastroenterology Source Type: research

Clinical profiles and mortality rates are similar for metabolic dysfunction-associated steatotic liver disease and non-alcoholic fatty liver disease
Metabolic dysfunction associated steatotic liver disease (MASLD) has replaced nonalcoholic fatty liver disease (NAFLD). Concern remains whether the evidence generated under NAFLD definition can be used for MASLD. We compared the clinical profile and outcomes of NAFLD to MASLD using tertiary-care and population-based data. (Source: Journal of Hepatology)
Source: Journal of Hepatology - January 26, 2024 Category: Gastroenterology Authors: Zobair M. Younossi, James M. Paik, Maria Stepanova, Janus Ong, Saleh Alqahtani, Linda Henry Tags: Research Article Source Type: research

A rare cause of liver fibrosis in an adult patient
A 41-year-old male, with a BMI of 27.2 kg/m2 and no alcohol consumption for the past 10 years, was referred by the GP to our Liver Unit with the suspicion of non-alcoholic fatty liver disease (NAFLD). The patient underwent a Fibroscan (special ultrasound technology that measures liver stiffness and fatty changes) with a result of 14.7 kPa (normal range: 4-7 kPa). His liver function tests have been persistently normal since presentation with alanine aminotransferase of 41 U/L (N 10-50 U/L), aspartate aminotransferase of 31 U/L (N 10-50 U/L), alkaline phosphatase of 118 U/L (N 0-29 U/L), serum urea of 7.3 mmol/L (N 2.1-7.1) ...
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Authors: Hiroshi Silva, Ji Jade King, Douglas Thorburn, Tu Vinh Luong Tags: What Is Your Diagnosis? Source Type: research

Editorial Board
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

Submit your late-breaker abstract for the EASL Congress 2024 between 27 March - 10 April.
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

Register now for the EASL Liver Cancer Summit 2024!
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

Let ’s unite Hepatology! Become an EASL member today and discover your benefits
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

EASL is supporting six major EU-funded projects on the liver. Discover them!
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

Contents
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research

JHEP at a glance (Month 20XX)
(Source: Journal of Hepatology)
Source: Journal of Hepatology - January 25, 2024 Category: Gastroenterology Source Type: research