Greatly increased giant platelets mimicking blasts in flow cytometric analysis from a patient with primary myelofibrosis
(Source: Journal of Hematopathology)
Source: Journal of Hematopathology - March 1, 2018 Category: Pathology Source Type: research
A case of very rare co-occurrence of POEMS syndrome and JAK2 V617F positive MPN
(Source: Journal of Hematopathology)
Source: Journal of Hematopathology - February 17, 2018 Category: Pathology Source Type: research
Greatly increased giant platelets mimicking blasts in flow cytometric analysis from a patient with primary myelofibrosis
(Source: Journal of Hematopathology)
Source: Journal of Hematopathology - February 7, 2018 Category: Pathology Source Type: research
Primary lymphomatous presentation of hairy cell leukemia as osteolytic vertebral lesions: a case report
AbstractHairy cell leukemia (HCL) is a rare and indolent mature B cell neoplasm. Most patients with HCL have excellent response to purine analogs and BRAF inhibitors. Therefore, it is clinically important to identify and differentiate HCL from other B cell neoplasms. HCL is predominantly found in the peripheral blood, bone marrow, or spleen. HCL presenting initially or solely in unusual sites is extremely rare (approximately ten or fewer). We hereby report a unique case of HCL presenting as vertebral osteolytic and epidural mass lesions without bone marrow, spleen, or peripheral blood involvement. The patient was a 53-year...
Source: Journal of Hematopathology - February 6, 2018 Category: Pathology Source Type: research
Isolated central nervous system post-transplant lymphoproliferative disorder in a pediatric patient: a case report with pathobiological perspective
We present a case of an 8-year-old male with a prior history of a kidney transplant who developed and ICNS-PTLD. We highlight the pathobiology and diagnostic features with a brief review of the literature on these rare cases. There is a complex interplay between CD30, Epstein Barr Virus and MYC as part of lymphocyte transformation leading to PTLD. In the appropriate clinical setting, CD30 and EBV positivity along with normal MYC expression are highly predictive of CNS-PTLD over a Primary CNS lymphoma. ICNS-PTLD has only been rarely reported in children. The faithful diagnosis is necessary for prognostication and to accrue ...
Source: Journal of Hematopathology - December 29, 2017 Category: Pathology Source Type: research
