Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditis elegans
Publication date: Available online 18 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Ruofeng Tang, Xin Wang, Junxiang Zhou, Fengxia Zhang, Shan Zhao, Qiwen Gan, Liyuan Zhao, Fengyang Wang, Qian Zhang, Jie Zhang, Guodong Wang, Chonglin Yang (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - April 16, 2020 Category: Genetics & Stem Cells Source Type: research

Severe cases of BCGosis-susceptible PID identified by next-generation sequencing: Implications for adjustment of BCG vaccination timing in China
Publication date: Available online 30 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Gang Liu, Haijuan Xiao, Linlin Liu, Lingyun Guo, Ruolan Guo, Xuyun Hu, Chanjuan Hao, Jingang Gui, Weiwei Jiao, Fang Xu, Adong Shen, Wei Li (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 31, 2020 Category: Genetics & Stem Cells Source Type: research

Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naïve CD4+ T cells
Publication date: Available online 25 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Anne-Marie Madore, Lucile Pain, Anne-Marie Boucher-Lafleur, Andréanne Morin, Jolyane Meloche, Marie-Michelle Simon, Bing Ge, Tony Kwan, Warren A. Cheung, Tomi Pastinen, Catherine Laprise (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 27, 2020 Category: Genetics & Stem Cells Source Type: research

Two homologous INDOLE-3-ACETAMIDE (IAM) HYDRALASE genes are required for the auxin effects of IAM in Arabidopsis
Publication date: Available online 19 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Yangbin Gao, Xinhau Dai, Yuki Aoi, Yumiko Takebayashi, Liping Yang, Xiaorui Guo, Qiwei Zeng, Hanchuanzhi Yu, Hiroyuki Kasahara, Yunde Zhao (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 21, 2020 Category: Genetics & Stem Cells Source Type: research

Drosophila P75 safeguards oogenesis by preventing H3K9me2 spreading
Publication date: Available online 19 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Kun Dou, Yanchao Liu, Yingpei Zhang, Chenhui Wang, Ying Huang, ZZ Zhao Zhang (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 21, 2020 Category: Genetics & Stem Cells Source Type: research

Clinical utility of whole genome sequencing for the detection of mitochondrial genome mutations
Publication date: Available online 19 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Ammar Husami, Jesse Slone, Jenice Brown, Meghan Bromwell, C. Alexander Valencia, Taosheng Huang (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 21, 2020 Category: Genetics & Stem Cells Source Type: research

The proline synthesis enzyme P5CS forms cytoophidia in Drosophila
Publication date: Available online 19 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Bo Zhang, Ömür Y. Tastan, Xian Zhou, Chen-Jun Guo, Xuyang Liu, Aaron Thind, Huan-Huan Hu, Suwen Zhao, Ji-Long Liu (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 20, 2020 Category: Genetics & Stem Cells Source Type: research

Porcine reproductive and respiratory syndrome virus (PRRSV) inhibition with engineered Cas13d
Publication date: Available online 17 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Guo Li, Xinjie Wang, Yajing Liu, Xinyuan Lv, Guanglei Li, Chengcheng Zhao, Dandan Wang, Xingxu Huang, Xiaoxiang Hu (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 18, 2020 Category: Genetics & Stem Cells Source Type: research

Defective arginine metabolism impairs mitochondrial homeostasis in C. elegans
Publication date: Available online 18 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Ruofeng Tang, Xin Wang, Junxiang Zhou, Fengxia Zhang, Shan Zhao, Qiwen Gan, Liyuan Zhao, Fengyang Wang, Qian Zhang, Jie Zhang, Guodong Wang, Chonglin Yang (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 18, 2020 Category: Genetics & Stem Cells Source Type: research

Identification of potential cross-protective epitope between a new type of coronavirus (2019-nCoV) and severe acute respiratory syndrome virus
Publication date: Available online 30 January 2020Source: Journal of Genetics and GenomicsAuthor(s): Tianyi Qiu, Tiantian Mao, Yuan Wang, Mengdi Zhou, Jingxuan Qiu, Jianwei Wang, Jianqing Xu, Zhiwei Cao (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 12, 2020 Category: Genetics & Stem Cells Source Type: research

Single-cell RNA sequencing identifies novel cell types in Drosophila blood
Publication date: Available online 9 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Yulong Fu, Xiaohu Huang, Peng Zhang, Joyce van de Leemput, Zhe Han (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 9, 2020 Category: Genetics & Stem Cells Source Type: research

Lessons from expanded potential of embryonic stem cells: Moving towards totipotency
Publication date: Available online 7 March 2020Source: Journal of Genetics and GenomicsAuthor(s): Rongrong Le, Yixin Huang, Anqi Zhao, Shaorong Gao (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - March 8, 2020 Category: Genetics & Stem Cells Source Type: research

Structural and immunogenomic insights into B-cell receptor activation
Publication date: Available online 9 January 2020Source: Journal of Genetics and GenomicsAuthor(s): Yangyang Feng, Yu Wang, Shaocun Zhang, Kabeer Haneef, Wanli Liu (Source: Journal of Genetics and Genomics)
Source: Journal of Genetics and Genomics - February 26, 2020 Category: Genetics & Stem Cells Source Type: research

Both combinatorial K4me0-K36me3 marks on sister histone H3s of a nucleosome are required for Dnmt3a-Dnmt3L mediated de novo DNA methylation
Publication date: Available online 21 February 2020Source: Journal of Genetics and GenomicsAuthor(s): Ting Gong, Xin Gu, Yuting Liu, Zhen Zhou, Lingli Zhang, Yang Wen, Weili Zhong, Guoliang Xu, Jin-Qiu ZhouAbstractA nucleosome contains two copies of each histone H2A, H2B, H3 and H4. Histone H3 K4me0 and K36me3 are two key chromatin marks for de novo DNA methylation catalyzed by DNA methyltransferases in mammals. However, it remains unclear whether K4me0 and K36me3 marks on both sister histone H3s regulate de novo DNA methylation independently or cooperatively. Here, taking advantage of the bivalent histone H3 system in yea...
Source: Journal of Genetics and Genomics - February 21, 2020 Category: Genetics & Stem Cells Source Type: research

Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance
Publication date: Available online 19 February 2020Source: Journal of Genetics and GenomicsAuthor(s): Adam F. Johnson, Jie Hou, Hua Yang, Xiaowen Shi, Chen Chen, Md Soliman Islam, Tieming Ji, Jianlin Cheng, James A. BirchlerAbstractAneuploidy has profound effects on an organism, typically more so than polyploidy, and the basis of this contrast is not fully understood. A dosage series of the maize long arm of chromosome 1 (1L) was used to compare relative global gene expression in different types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene ...
Source: Journal of Genetics and Genomics - February 20, 2020 Category: Genetics & Stem Cells Source Type: research